Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100777003 | . | A | C | CCDS5711.1:NM_000602.4:c.728tAc>tCc_NP_000593.1:p.243Y>S | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | TYR | A:243 | A:243 | 72.0 | 0.313 | E | -88.8 | 135.1 | 72.0 | 0.313 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | TYR | A:220 | A:220 | 102.0 | 0.443 | E | -85.4 | 126.5 | 102.0 | 0.443 | 0.0 |
HOH |
6.310 |
CD2 |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | TYR | A:220 | A:220 | 130.0 | 0.565 | E | -87.4 | 146.3 | 130.0 | 0.565 | 0.0 |
HOH |
3.047 |
N |
O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | TYR | A:224 | A:220 | 100.0 | 0.435 | E | -98.9 | 147.7 | 100.0 | 0.435 | 0.0 |
HOH |
5.589 |
OH |
O |
||
| TYR | B:224 | B:220 | 106.0 | 0.461 | E | -91.5 | 143.4 | NA | NA | NA | |||||||||||||
| TYR | C:224 | C:220 | 115.0 | 0.5 | E | -102.2 | 140.7 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | TYR | A:220 | A:220 | 114.0 | 0.496 | E | -84.0 | 149.2 | 114.0 | 0.496 | 0.0 |
RIP HOH |
7.567 2.720 |
CA O |
O3 O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | TYR | A:220 | A:220 | 143.0 | 0.622 | E | -84.8 | 144.0 | 143.0 | 0.622 | 0.0 |
HOH |
5.651 |
O |
O |
||
| TYR | B:220 | B:220 | 137.0 | 0.596 | E | -88.9 | 143.7 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | TYR | A:220 | A:220 | 122.0 | 0.53 | E | -78.9 | 143.0 | 122.0 | 0.53 | 0.0 |
HOH |
2.651 |
O |
O |
||
| TYR | B:220 | B:220 | 120.0 | 0.522 | E | -79.4 | 141.2 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | TYR | A:220 | A:220 | 75.0 | 0.326 | E | -123.9 | 166.7 | 19.0 | 0.083 | 0.243 |
B:None:0.243 |
HOH |
2.663 |
OH |
O |
|
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | TYR | A:220 | A:220 | 119.0 | 0.517 | E | -86.1 | 138.8 | 119.0 | 0.517 | 0.0 |
HOH |
2.807 |
O |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | TYR | A:220 | A:220 | 74.0 | 0.322 | E | -116.2 | 163.1 | 17.0 | 0.074 | 0.248 |
B:None:0.248 |
HOH |
2.902 |
O |
O |
|
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | TYR | A:220 | A:243 | 124.0 | 0.539 | E | -85.9 | 146.4 | 124.0 | 0.539 | 0.0 |
FUC |
6.759 |
CE2 |
O3 |
||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | TYR | A:233 | A:220 | 134.0 | 0.583 | E | -91.6 | 144.6 | 134.0 | 0.583 | 0.0 |
HOH |
2.019 |
H |
O |
||
| TYR | B:233 | B:220 | 128.0 | 0.557 | E | -91.8 | 138.1 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | TYR | A:220 | A:220 | 112.0 | 0.487 | E | -108.6 | 117.9 | 112.0 | 0.487 | 0.0 | ||||||
| TYR | B:220 | B:220 | 112.0 | 0.487 | E | -108.0 | 117.4 | NA | NA | NA | |||||||||||||
| TYR | C:220 | C:220 | 115.0 | 0.5 | E | -107.0 | 117.1 | NA | NA | NA | |||||||||||||
| TYR | D:220 | D:220 | 112.0 | 0.487 | E | -107.7 | 115.9 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | TYR | A:220 | A:220 | 135.0 | 0.587 | E | -78.7 | 135.1 | 135.0 | 0.587 | 0.0 |
HOH |
2.872 |
OH |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | TYR | A:220 | I:220 | 108.0 | 0.47 | E | -105.2 | 141.7 | 108.0 | 0.47 | 0.0 | ||||||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | TYR | A:220 | A:220 | 125.0 | 0.543 | E | -80.3 | 136.3 | 60.0 | 0.261 | 0.282 |
I:None:0.283 |
HOH |
5.659 |
OH |
O |
|
| TYR | B:220 | B:220 | 131.0 | 0.57 | E | -77.5 | 126.0 | NA | NA | NA | |||||||||||||
| TYR | C:220 | C:220 | 134.0 | 0.583 | E | -87.7 | 134.1 | NA | NA | NA | |||||||||||||
| TYR | D:220 | D:220 | 123.0 | 0.535 | E | -81.6 | 126.2 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | TYR | A:220 | A:220 | 107.0 | 0.465 | E | -98.9 | 129.7 | 107.0 | 0.465 | 0.0 |
HOH |
4.623 |
CD2 |
O |
||
| TYR | B:220 | B:220 | 120.0 | 0.522 | E | -74.9 | 147.7 | NA | NA | NA | |||||||||||||
| TYR | C:220 | C:220 | 126.0 | 0.548 | E | -79.1 | 140.9 | NA | NA | NA | |||||||||||||
| TYR | D:220 | D:220 | 130.0 | 0.565 | E | -86.9 | 138.4 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | TYR | A:220 | I:220 | 121.0 | 0.526 | E | -79.6 | 145.5 | 106.0 | 0.461 | 0.065 |
B:Q5SWW8:0.065 |
HOH |
2.692 |
O |
O |
|
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | TYR | A:220 | A:220 | 94.0 | 0.409 | E | -99.6 | 146.4 | 94.0 | 0.409 | 0.0 | ||||||
| TYR | B:220 | B:220 | 137.0 | 0.596 | E | -71.1 | 139.2 | NA | NA | NA | |||||||||||||
| TYR | C:220 | C:220 | 86.0 | 0.374 | E | -100.6 | 139.9 | NA | NA | NA | |||||||||||||
| TYR | D:220 | D:220 | 117.0 | 0.509 | E | -73.1 | 136.8 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | TYR | A:220 | A:220 | 82.0 | 0.357 | E | -84.8 | 133.8 | 82.0 | 0.357 | 0.0 |
HOH |
2.912 |
O |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | TYR | A:220 | A:220 | 69.0 | 0.3 | E | -105.4 | 155.3 | 27.0 | 0.117 | 0.183 |
B:None:0.183 |
HOH |
2.846 |
N |
O |
|
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | TYR | A:220 | A:220 | 96.0 | 0.417 | E | -106.9 | 129.7 | 30.0 | 0.13 | 0.287 |
B:None:0.287 |
HOH |
2.971 |
N |
O |
|
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | TYR | A:220 | A:220 | 129.0 | 0.561 | E | -73.4 | 145.4 | 129.0 | 0.561 | 0.0 |
HOH |
2.684 |
O |
O |
||
| TYR | B:220 | B:220 | 110.0 | 0.478 | E | -107.5 | 142.8 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | TYR | A:218 | A:220 | 112.0 | 0.487 | E | -92.0 | 133.7 | 112.0 | 0.487 | 0.0 | ||||||
| TYR | B:218 | B:220 | 114.0 | 0.496 | E | -86.9 | 141.8 | 114.0 | 0.496 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | TYR | A:217 | A:220 | 133.0 | 0.578 | E | -76.0 | 141.6 | 133.0 | 0.578 | 0.0 |
HOH |
4.042 |
CG |
O |
||
| TYR | B:217 | B:220 | 127.0 | 0.552 | E | -79.5 | 145.0 | NA | NA | NA | |||||||||||||
| TYR | C:217 | C:220 | 119.0 | 0.517 | E | -103.9 | 137.2 | NA | NA | NA | |||||||||||||
| TYR | D:217 | D:220 | 131.0 | 0.57 | E | -101.2 | 139.3 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | TYR | A:217 | A:220 | 135.0 | 0.587 | E | -74.8 | 142.8 | 135.0 | 0.587 | 0.0 |
HOH |
2.618 |
O |
O |
||
| TYR | B:217 | B:220 | 26.0 | NA | E | -99.2 | 135.6 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | TYR | A:216 | A:220 | 108.0 | 0.47 | E | -107.7 | 133.9 | 108.0 | 0.47 | 0.0 | ||||||
| TYR | B:216 | B:220 | 128.0 | 0.557 | E | -70.0 | 148.9 | NA | NA | NA | |||||||||||||
| TYR | C:216 | C:220 | 107.0 | 0.465 | E | -103.0 | 143.3 | NA | NA | NA | |||||||||||||
| TYR | D:216 | D:220 | 133.0 | 0.578 | E | -81.2 | 148.0 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | TYR | A:215 | I:220 | 117.0 | 0.509 | B | -100.9 | 131.7 | 117.0 | 0.509 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | TYR | A:220 | A:238 | 112.0 | 0.487 | E | -95.4 | 130.1 | 112.0 | 0.487 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | GLU | A:220 | A:220 | 90.0 | 0.474 | E | -87.1 | 144.6 | 90.0 | 0.474 | 0.0 |
HOH |
2.690 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | TYR | A:243 | A:243 | 129.0 | 0.561 | E | -74.7 | 142.8 | |