Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100777032 | . | G | A | CCDS5711.1:NM_000602.4:c.757Ggg>Agg_NP_000593.1:p.253G>R | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | GLY | A:253 | A:253 | 18.0 | 0.24 | T | -92.5 | -7.2 | 18.0 | 0.24 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | GLY | A:230 | A:230 | 15.0 | 0.2 | T | -78.6 | -11.7 | 15.0 | 0.2 | 0.0 |
HOH |
2.703 |
O |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | GLY | A:230 | A:230 | 19.0 | 0.253 | T | -90.1 | -4.5 | 19.0 | 0.253 | 0.0 |
DMS HOH |
9.707 2.802 |
N O |
O O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | GLY | A:234 | A:230 | 6.0 | 0.08 | T | -77.0 | -8.3 | 6.0 | 0.08 | 0.0 |
HOH |
3.113 |
CA |
O |
||
| GLY | B:234 | B:230 | 6.0 | 0.08 | T | -83.1 | -9.6 | NA | NA | NA | |||||||||||||
| GLY | C:234 | C:230 | 4.0 | 0.053 | T | -70.5 | -18.2 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | GLY | A:230 | A:230 | 5.0 | 0.067 | T | -82.8 | -7.2 | 5.0 | 0.067 | 0.0 |
NAG HOH |
8.687 3.279 |
C CA |
O3 O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | GLY | A:230 | A:230 | 31.0 | 0.413 | T | 109.6 | -23.5 | 31.0 | 0.413 | 0.0 | ||||||
| GLY | B:230 | B:230 | 42.0 | 0.56 | T | 108.9 | -24.3 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | GLY | A:230 | A:230 | 9.0 | 0.12 | T | -77.1 | -6.0 | 9.0 | 0.12 | 0.0 |
HOH |
3.015 |
CA |
O |
||
| GLY | B:230 | B:230 | 46.0 | 0.613 | T | 120.8 | -10.6 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | GLY | A:230 | A:230 | 51.0 | 0.68 | T | 105.1 | -18.6 | 51.0 | 0.68 | 0.0 |
HOH |
6.538 |
O |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | GLY | A:230 | A:230 | 21.0 | 0.28 | T | -67.7 | -11.1 | 21.0 | 0.28 | 0.0 |
HOH |
4.819 |
N |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | GLY | A:230 | A:230 | 53.0 | 0.707 | T | 104.0 | -16.9 | 53.0 | 0.707 | 0.0 | ||||||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | GLY | A:230 | A:253 | 65.0 | 0.867 | G | 59.8 | 3.7 | 65.0 | 0.867 | 0.0 |
NAG |
8.948 |
C |
O3 |
||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | GLY | A:243 | A:230 | 10.0 | 0.133 | T | -76.4 | -15.4 | 10.0 | 0.133 | 0.0 |
HOH |
2.545 |
HA3 |
O |
||
| GLY | B:243 | B:230 | 10.0 | 0.133 | T | -73.4 | -15.7 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | GLY | A:230 | A:230 | 59.0 | 0.787 | G | 61.7 | 13.3 | 59.0 | 0.787 | 0.0 | ||||||
| GLY | B:230 | B:230 | 59.0 | 0.787 | G | 61.2 | 12.6 | NA | NA | NA | |||||||||||||
| GLY | C:230 | C:230 | 60.0 | 0.8 | G | 61.7 | 15.8 | NA | NA | NA | |||||||||||||
| GLY | D:230 | D:230 | 61.0 | 0.813 | G | 60.4 | 13.5 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | GLY | A:230 | A:230 | 61.0 | 0.813 | G | 69.9 | 12.2 | 61.0 | 0.813 | 0.0 |
HOH |
3.587 |
CA |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:230 | I:230 | 62.0 | 0.827 | G | 71.7 | 4.3 | 62.0 | 0.827 | 0.0 | ||||||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | GLY | A:230 | A:230 | 63.0 | 0.84 | G | 75.6 | 11.1 | 63.0 | 0.84 | 0.0 | ||||||
| GLY | B:230 | B:230 | 64.0 | 0.853 | G | 71.2 | 13.5 | NA | NA | NA | |||||||||||||
| GLY | C:230 | C:230 | 68.0 | 0.907 | G | 72.2 | 12.0 | NA | NA | NA | |||||||||||||
| GLY | D:230 | D:230 | 63.0 | 0.84 | G | 69.4 | 12.7 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | GLY | A:230 | A:230 | 58.0 | 0.773 | G | 79.3 | 2.1 | 58.0 | 0.773 | 0.0 |
HOH |
3.159 |
O |
O |
||
| GLY | B:230 | B:230 | 63.0 | 0.84 | G | 85.0 | -14.8 | NA | NA | NA | |||||||||||||
| GLY | C:230 | C:230 | 57.0 | 0.76 | T | 88.7 | 1.5 | NA | NA | NA | |||||||||||||
| GLY | D:230 | D:230 | 71.0 | 0.947 | G | 75.2 | 1.5 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | GLY | A:230 | I:230 | 32.0 | 0.427 | G | 70.7 | 1.3 | 32.0 | 0.427 | 0.0 |
HOH |
3.462 |
CA |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | GLY | A:230 | A:230 | 57.0 | 0.76 | G | 77.1 | 3.5 | 57.0 | 0.76 | 0.0 | ||||||
| GLY | B:230 | B:230 | 69.0 | 0.92 | G | 72.9 | -3.0 | NA | NA | NA | |||||||||||||
| GLY | C:230 | C:230 | 57.0 | 0.76 | G | 79.8 | -2.8 | NA | NA | NA | |||||||||||||
| GLY | D:230 | D:230 | 59.0 | 0.787 | G | 81.4 | 4.2 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | GLY | A:230 | A:230 | 10.0 | 0.133 | T | -78.7 | -12.5 | 10.0 | 0.133 | 0.0 |
HOH |
2.888 |
O |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | GLY | A:230 | A:230 | 62.0 | 0.827 | T | 115.3 | -14.7 | 62.0 | 0.827 | 0.0 | ||||||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | GLY | A:230 | A:230 | 34.0 | 0.453 | S | -95.8 | 122.6 | 34.0 | 0.453 | 0.0 | ||||||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | GLY | A:230 | A:230 | 40.0 | 0.533 | T | -62.1 | -7.3 | 40.0 | 0.533 | 0.0 |
HOH |
4.883 |
N |
O |
||
| GLY | B:230 | B:230 | 60.0 | 0.8 | G | 68.8 | 3.7 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | GLY | A:228 | A:230 | 60.0 | 0.8 | G | 96.2 | -20.3 | 60.0 | 0.8 | 0.0 | ||||||
| GLY | B:228 | B:230 | 58.0 | 0.773 | G | 86.0 | -10.7 | 58.0 | 0.773 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | GLY | A:227 | A:230 | 65.0 | 0.867 | G | 72.7 | 11.5 | 65.0 | 0.867 | 0.0 |
HOH |
9.688 |
N |
O |
||
| GLY | B:227 | B:230 | 63.0 | 0.84 | G | 70.3 | 9.4 | NA | NA | NA | |||||||||||||
| GLY | C:227 | C:230 | 65.0 | 0.867 | G | 74.9 | 2.2 | NA | NA | NA | |||||||||||||
| GLY | D:227 | D:230 | 61.0 | 0.813 | G | 70.1 | 10.2 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | GLY | A:227 | A:230 | 62.0 | 0.827 | G | 79.9 | 6.3 | 62.0 | 0.827 | 0.0 |
HOH |
4.664 |
C |
O |
||
| GLY | B:227 | B:230 | 64.0 | 0.853 | G | 67.3 | 2.8 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | GLY | A:226 | A:230 | 60.0 | 0.8 | G | 71.1 | -2.5 | 60.0 | 0.8 | 0.0 | ||||||
| GLY | B:226 | B:230 | 59.0 | 0.787 | T | 83.9 | -13.2 | NA | NA | NA | |||||||||||||
| GLY | C:226 | C:230 | 62.0 | 0.827 | G | 76.8 | -5.4 | NA | NA | NA | |||||||||||||
| GLY | D:226 | D:230 | 51.0 | 0.68 | T | 89.5 | -18.2 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | GLY | A:225 | I:230 | 59.0 | 0.787 | G | 69.5 | 7.7 | 59.0 | 0.787 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | GLY | A:230 | A:248 | 13.0 | 0.173 | T | -84.2 | -16.1 | 13.0 | 0.173 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | GLY | A:230 | A:230 | 21.0 | 0.28 | S | 86.2 | -162.6 | 21.0 | 0.28 | 0.0 |
HOH |
2.914 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | GLY | A:253 | A:253 | 45.0 | 0.6 | T | 92.9 | 0.3 | |