Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100777036 | . | A | C | CCDS5711.1:NM_000602.4:c.761gAc>gCc_NP_000593.1:p.254D>A | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | ASP | A:254 | A:254 | 97.0 | 0.647 | S | 68.9 | 7.3 | 97.0 | 0.647 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | ASP | A:231 | A:231 | 98.0 | 0.653 | S | 60.2 | 20.8 | 98.0 | 0.653 | 0.0 |
HOH |
2.999 |
O |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | ASP | A:231 | A:231 | 93.0 | 0.62 | S | 58.8 | 23.7 | 93.0 | 0.62 | 0.0 |
DMS HOH |
6.746 2.889 |
OD1 O |
C2 O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | ASP | A:235 | A:231 | 109.0 | 0.727 | S | 69.9 | 5.1 | 109.0 | 0.727 | 0.0 |
HOH |
3.371 |
N |
O |
||
| ASP | B:235 | B:231 | 98.0 | 0.653 | S | 69.4 | 15.4 | NA | NA | NA | |||||||||||||
| ASP | C:235 | C:231 | 97.0 | 0.647 | S | 67.5 | 12.8 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | ASP | A:231 | A:231 | 98.0 | 0.653 | S | 66.9 | 9.8 | 98.0 | 0.653 | 0.0 |
NAG HOH |
4.396 3.370 |
OD1 N |
O3 O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ASP | A:231 | A:231 | 110.0 | 0.733 | S | 68.3 | 31.1 | 110.0 | 0.733 | 0.0 | ||||||
| ASP | B:231 | B:231 | 123.0 | 0.82 | S | 72.3 | 20.6 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ASP | A:231 | A:231 | 97.0 | 0.647 | S | 60.0 | 24.7 | 97.0 | 0.647 | 0.0 |
HOH |
3.328 |
N |
O |
||
| ASP | B:231 | B:231 | 112.0 | 0.747 | S | 55.4 | 32.8 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | ASP | A:231 | A:231 | 113.0 | 0.753 | S | 54.2 | 36.0 | 113.0 | 0.753 | 0.0 |
HOH |
7.349 |
C |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | ASP | A:231 | A:231 | 106.0 | 0.707 | S | 69.4 | 5.5 | 106.0 | 0.707 | 0.0 |
HOH |
3.819 |
OD2 |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | ASP | A:231 | A:231 | 103.0 | 0.687 | S | 60.2 | 23.5 | 103.0 | 0.687 | 0.0 | ||||||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | ASP | A:231 | A:254 | 73.0 | 0.487 | G | 72.9 | 20.5 | 73.0 | 0.487 | 0.0 |
NAG |
4.579 |
OD2 |
O3 |
||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | ASP | A:244 | A:231 | 106.0 | 0.707 | S | 71.9 | 6.1 | 106.0 | 0.707 | 0.0 |
HOH |
2.493 |
HA |
O |
||
| ASP | B:244 | B:231 | 103.0 | 0.687 | S | 67.9 | 12.2 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | ASP | A:231 | A:231 | 75.0 | 0.5 | G | 49.8 | 17.6 | 75.0 | 0.5 | 0.0 | ||||||
| ASP | B:231 | B:231 | 76.0 | 0.507 | G | 51.0 | 16.6 | NA | NA | NA | |||||||||||||
| ASP | C:231 | C:231 | 77.0 | 0.513 | G | 48.3 | 15.1 | NA | NA | NA | |||||||||||||
| ASP | D:231 | D:231 | 77.0 | 0.513 | G | 50.8 | 17.4 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | ASP | A:231 | A:231 | 72.0 | 0.48 | G | 64.9 | 9.4 | 72.0 | 0.48 | 0.0 |
HOH |
4.387 |
C |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:231 | I:231 | 63.0 | 0.42 | G | 68.0 | 12.6 | 63.0 | 0.42 | 0.0 | ||||||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | ASP | A:231 | A:231 | 74.0 | 0.493 | G | 56.3 | 11.9 | 74.0 | 0.493 | 0.0 |
HOH |
8.455 |
OD1 |
O |
||
| ASP | B:231 | B:231 | 74.0 | 0.493 | G | 58.5 | 2.3 | NA | NA | NA | |||||||||||||
| ASP | C:231 | C:231 | 56.0 | 0.373 | G | 59.1 | 0.5 | NA | NA | NA | |||||||||||||
| ASP | D:231 | D:231 | 75.0 | 0.5 | G | 53.6 | 14.7 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | ASP | A:231 | A:231 | 70.0 | 0.467 | G | 60.6 | 21.4 | 70.0 | 0.467 | 0.0 |
HOH |
4.231 |
O |
O |
||
| ASP | B:231 | B:231 | 75.0 | 0.5 | G | 68.9 | 14.4 | NA | NA | NA | |||||||||||||
| ASP | C:231 | C:231 | 83.0 | 0.553 | S | 56.4 | 5.7 | NA | NA | NA | |||||||||||||
| ASP | D:231 | D:231 | 74.0 | 0.493 | G | 69.6 | 10.5 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | ASP | A:231 | I:231 | 69.0 | 0.46 | G | 70.2 | 11.7 | 69.0 | 0.46 | 0.0 |
HOH |
2.556 |
O |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | ASP | A:231 | A:231 | 78.0 | 0.52 | G | 68.0 | 14.4 | 78.0 | 0.52 | 0.0 | ||||||
| ASP | B:231 | B:231 | 67.0 | 0.447 | G | 68.6 | 9.1 | NA | NA | NA | |||||||||||||
| ASP | C:231 | C:231 | 66.0 | 0.44 | G | 71.5 | 15.5 | NA | NA | NA | |||||||||||||
| ASP | D:231 | D:231 | 73.0 | 0.487 | G | 70.1 | 2.7 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | ASP | A:231 | A:231 | 100.0 | 0.667 | S | 64.7 | 18.1 | 100.0 | 0.667 | 0.0 |
HOH |
2.782 |
OD2 |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ASP | A:231 | A:231 | 116.0 | 0.773 | S | 61.6 | 18.0 | 116.0 | 0.773 | 0.0 | ||||||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ASP | A:231 | A:231 | 124.0 | 0.827 | T | -50.7 | -22.1 | 124.0 | 0.827 | 0.0 |
HOH |
8.510 |
OD1 |
O |
||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | ASP | A:231 | A:231 | 72.0 | NA | S | 66.6 | -0.2 | 72.0 | NA | NA |
HOH |
5.789 |
O |
O |
||
| ASP | B:231 | B:231 | 70.0 | 0.467 | G | 61.4 | 17.3 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | ASP | A:229 | A:231 | 69.0 | 0.46 | G | 71.9 | 24.9 | 69.0 | 0.46 | 0.0 | ||||||
| ASP | B:229 | B:231 | 69.0 | 0.46 | G | 68.0 | 24.4 | 69.0 | 0.46 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ASP | A:228 | A:231 | 61.0 | 0.407 | G | 58.6 | 12.7 | 61.0 | 0.407 | 0.0 |
HOH |
8.950 |
OD2 |
O |
||
| ASP | B:228 | B:231 | 64.0 | 0.427 | G | 58.8 | 23.3 | NA | NA | NA | |||||||||||||
| ASP | C:228 | C:231 | 74.0 | 0.493 | G | 59.0 | 31.0 | NA | NA | NA | |||||||||||||
| ASP | D:228 | D:231 | 79.0 | 0.527 | G | 56.0 | 24.7 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ASP | A:228 | A:231 | 81.0 | 0.54 | G | 55.9 | 28.2 | 81.0 | 0.54 | 0.0 |
HOH |
4.241 |
N |
O |
||
| ASP | B:228 | B:231 | 70.0 | 0.467 | G | 64.9 | 17.6 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | ASP | A:227 | A:231 | 75.0 | 0.5 | G | 65.1 | 21.2 | 75.0 | 0.5 | 0.0 | ||||||
| ASP | B:227 | B:231 | 81.0 | 0.54 | S | 62.5 | -1.7 | NA | NA | NA | |||||||||||||
| ASP | C:227 | C:231 | 69.0 | 0.46 | G | 67.9 | 18.4 | NA | NA | NA | |||||||||||||
| ASP | D:227 | D:231 | 78.0 | 0.52 | S | 75.9 | -9.1 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | ASP | A:226 | I:231 | 83.0 | 0.553 | G | 55.3 | 23.2 | 83.0 | 0.553 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | ASP | A:231 | A:249 | 96.0 | 0.64 | S | 60.2 | 15.1 | 91.0 | 0.607 | 0.033 |
B:P05121:0.033 |
|||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | ASP | A:231 | A:231 | 140.0 | 0.933 | S | -134.3 | 23.4 | 140.0 | 0.933 | 0.0 |
HOH |
2.582 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | ASP | A:254 | A:254 | 74.0 | 0.493 | S | 60.4 | 8.2 | |