Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100777114 . A C CCDS5711.1:NM_000602.4:c.839cAg>cCg_NP_000593.1:p.280Q>P Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 GLN A:280 A:280 104.0 0.578 H -85.9 -24.9 104.0 0.578 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 GLN A:257 A:257 103.0 0.572 H -71.5 -39.0 103.0 0.572 0.0 HOH
 2.853
 NE2
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 GLN A:257 A:257 113.0 0.628 H -61.2 -41.5 113.0 0.628 0.0 HOH
 2.684
 NE2
 O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 GLN A:261 A:257 71.0 0.394 H -70.4 -34.1 71.0 0.394 0.0 HOH
 4.615
 CB
 O
GLN B:261 B:257 70.0 0.389 H -66.2 -35.4 NA NA NA
GLN C:261 C:257 75.0 0.417 H -64.9 -36.9 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 GLN A:257 A:257 126.0 0.7 H -67.9 -39.9 126.0 0.7 0.0 NAG
NAG
RIP
HOH
 6.787
6.485
9.450
2.938
 O
OE1
O
N
 O7
C3
C1
O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 GLN A:257 A:257 112.0 0.622 H -62.9 -44.4 112.0 0.622 0.0 HOH
 3.190
 N
 O
GLN B:257 B:257 106.0 0.589 H -74.5 -31.3 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 GLN A:257 A:257 107.0 0.594 H -69.5 -39.2 107.0 0.594 0.0 ZN
HOH
 4.550
3.075
 CG
CG
 ZN
O
GLN B:257 B:257 113.0 0.628 H -68.3 -40.7 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 GLN A:257 A:257 94.0 0.522 H -65.0 -41.2 94.0 0.522 0.0 HOH
 2.526
 OE1
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 GLN A:257 A:257 125.0 0.694 H -69.6 -37.2 125.0 0.694 0.0 HOH
 4.882
 N
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 GLN A:257 A:257 119.0 0.661 H -69.2 -40.4 118.0 0.656 0.005 B:None:0.006
 HOH
 4.827
 N
 O
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 GLN A:257 A:280 109.0 0.606 H -62.9 -42.0 109.0 0.606 0.0 NAG
NAG
BMA
BMA
FUC
HOH
 6.507
5.658
7.816
8.639
9.621
3.921
 OE1
NE2
NE2
CG
O
NE2
 O7
O6
O2
O6
C1
O
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 GLN A:270 A:257 137.0 0.761 H -75.2 -36.0 137.0 0.761 0.0 HOH
 1.924
 HE21
 O
GLN B:270 B:257 142.0 0.789 H -63.4 -37.0 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 GLN A:257 A:257 122.0 0.678 H -68.9 -54.3 122.0 0.678 0.0
GLN B:257 B:257 125.0 0.694 H -67.9 -56.7 NA NA NA
GLN C:257 C:257 122.0 0.678 H -69.1 -53.7 NA NA NA
GLN D:257 D:257 124.0 0.689 H -68.0 -56.0 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 GLN A:257 A:257 120.0 0.667 H -60.6 -56.7 120.0 0.667 0.0 HOH
 4.962
 N
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 GLN A:257 I:257 131.0 0.728 H -84.0 -8.6 131.0 0.728 0.0 HOH
 2.611
 OE1
 O
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 GLN A:257 A:257 136.0 0.756 H -71.8 -38.8 136.0 0.756 0.0
GLN B:257 B:257 113.0 0.628 H -72.8 -35.9 NA NA NA
GLN C:257 C:257 112.0 0.622 H -60.8 -42.1 NA NA NA
GLN D:257 D:257 107.0 0.594 H -70.2 -37.1 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 GLN A:257 A:257 139.0 0.772 H -75.0 -18.4 139.0 0.772 0.0 HOH
 3.153
 N
 O
GLN B:257 B:257 139.0 0.772 H -77.0 -34.4 NA NA NA
GLN C:257 C:257 117.0 0.65 H -71.2 -28.8 NA NA NA
GLN D:257 D:257 122.0 0.678 H -64.4 -33.5 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 GLN A:257 I:257 100.0 0.556 H -68.3 -30.6 100.0 0.556 0.0 HOH
 2.423
 NE2
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 GLN A:257 A:257 105.0 0.583 H -61.8 -37.9 105.0 0.583 0.0
GLN B:257 B:257 133.0 0.739 H -68.5 -37.1 NA NA NA
GLN C:257 C:257 110.0 0.611 H -63.5 -36.4 NA NA NA
GLN D:257 D:257 126.0 0.7 H -64.9 -39.7 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 GLN A:257 A:257 117.0 0.65 H -65.6 -42.3 117.0 0.65 0.0 HOH
 6.357
 O
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 GLN A:257 A:257 102.0 0.567 H -65.9 -47.7 102.0 0.567 0.0 HOH
 5.043
 N
 O
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 GLN A:257 A:257 124.0 0.689 H -49.5 -43.1 116.0 0.644 0.045 B:None:0.044
 HOH
 9.194
 OE1
 O
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 GLN A:257 A:257 81.0 NA H -61.5 -42.8 81.0 NA NA HOH
 2.888
 O
 O
GLN B:257 B:257 116.0 0.644 H -70.6 -33.4 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 GLN A:255 A:257 104.0 0.578 H -68.7 -41.2 104.0 0.578 0.0
GLN B:255 B:257 102.0 0.567 H -64.9 -43.9 102.0 0.567 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 GLN A:254 A:257 126.0 0.7 H -71.9 -45.0 126.0 0.7 0.0 HOH
 4.119
 CG
 O
GLN B:254 B:257 135.0 0.75 H -67.2 -43.0 NA NA NA
GLN C:254 C:257 131.0 0.728 H -67.6 -35.6 NA NA NA
GLN D:254 D:257 121.0 0.672 H -67.0 -32.9 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 GLN A:254 A:257 146.0 0.811 H -65.1 -46.4 146.0 0.811 0.0 HOH
 4.593
 NE2
 O
GLN B:254 B:257 113.0 0.628 H -63.5 -36.4 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 GLN A:253 A:257 120.0 0.667 H -64.3 -40.7 120.0 0.667 0.0
GLN B:253 B:257 98.0 0.544 H -69.9 -46.3 NA NA NA
GLN C:253 C:257 139.0 0.772 H -68.1 -39.9 NA NA NA
GLN D:253 D:257 123.0 0.683 H -68.1 -44.6 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 GLN A:252 I:257 126.0 0.7 H -67.4 -26.0 126.0 0.7 0.0
9pai 1 P05121 99.71 0.0 X-RAY
 1999-03-19 GLN A:257 A:275 109.0 0.606 H -72.0 -46.2 109.0 0.606 0.0
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 GLU A:257 A:257 76.0 0.4 H -63.9 -42.6 76.0 0.4 0.0 HOH
 3.094
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 GLN A:280 A:280 92.0 0.511 H -67.0 -47.5