Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100777150 | . | T | A | CCDS5711.1:NM_000602.4:c.875cTg>cAg_NP_000593.1:p.292L>Q | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | LEU | A:292 | A:292 | 61.0 | 0.359 | E | -103.5 | 154.9 | 61.0 | 0.359 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | LEU | A:269 | A:269 | 70.0 | 0.412 | E | -124.0 | 145.6 | 70.0 | 0.412 | 0.0 |
HOH |
3.606 |
CB |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | LEU | A:269 | A:269 | 68.0 | 0.4 | E | -134.2 | 157.7 | 68.0 | 0.4 | 0.0 |
DMS HOH |
7.680 3.501 |
O CD1 |
C1 O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | LEU | A:273 | A:269 | 58.0 | 0.341 | E | -144.1 | 150.3 | 58.0 | 0.341 | 0.0 |
HOH |
3.906 |
CD2 |
O |
||
| LEU | B:273 | B:269 | 54.0 | 0.318 | E | -126.6 | 147.6 | NA | NA | NA | |||||||||||||
| LEU | C:273 | C:269 | 54.0 | 0.318 | E | -122.5 | 150.6 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | LEU | A:269 | A:269 | 59.0 | 0.347 | E | -132.2 | 147.4 | 59.0 | 0.347 | 0.0 |
NAG HOH |
7.722 3.654 |
N CD1 |
C8 O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | LEU | A:269 | A:269 | 55.0 | 0.324 | E | -132.6 | 133.2 | 55.0 | 0.324 | 0.0 |
HOH |
7.387 |
O |
O |
||
| LEU | B:269 | B:269 | 57.0 | 0.335 | E | -133.5 | 146.0 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | LEU | A:269 | A:269 | 55.0 | 0.324 | E | -148.3 | 141.8 | 55.0 | 0.324 | 0.0 |
HOH |
7.545 |
N |
O |
||
| LEU | B:269 | B:269 | 57.0 | 0.335 | E | -112.4 | 145.6 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | LEU | A:269 | A:269 | 53.0 | 0.312 | E | -100.4 | 144.4 | 53.0 | 0.312 | 0.0 |
HOH |
6.389 |
CD2 |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | LEU | A:269 | A:269 | 51.0 | 0.3 | E | -121.8 | 139.5 | 51.0 | 0.3 | 0.0 |
HOH |
3.898 |
CD1 |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | LEU | A:269 | A:269 | 41.0 | 0.241 | E | -124.9 | 141.6 | 41.0 | 0.241 | 0.0 | ||||||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | LEU | A:269 | A:292 | 60.0 | 0.353 | E | -153.9 | 144.9 | 60.0 | 0.353 | 0.0 |
NAG |
7.905 |
N |
O7 |
||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | LEU | A:282 | A:269 | 58.0 | 0.341 | E | -137.5 | 147.3 | 58.0 | 0.341 | 0.0 |
HOH |
4.257 |
HA |
O |
||
| LEU | B:282 | B:269 | 57.0 | 0.335 | E | -135.4 | 141.1 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | LEU | A:269 | A:269 | 52.0 | 0.306 | E | -140.3 | 142.8 | 52.0 | 0.306 | 0.0 | ||||||
| LEU | B:269 | B:269 | 51.0 | 0.3 | E | -138.4 | 143.9 | NA | NA | NA | |||||||||||||
| LEU | C:269 | C:269 | 51.0 | 0.3 | E | -138.7 | 143.3 | NA | NA | NA | |||||||||||||
| LEU | D:269 | D:269 | 52.0 | 0.306 | E | -138.2 | 143.7 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | LEU | A:269 | A:269 | 88.0 | 0.518 | E | -122.0 | 145.4 | 88.0 | 0.518 | 0.0 |
HOH |
2.704 |
O |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | LEU | A:269 | I:269 | 45.0 | 0.265 | E | -129.8 | 142.3 | 26.0 | 0.153 | 0.112 |
B:P00750:0.112 |
HOH |
7.218 |
C |
O |
|
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | LEU | A:269 | A:269 | 52.0 | 0.306 | E | -128.6 | 144.8 | 3.0 | 0.018 | 0.288 |
I:None:0.288 |
HOH |
6.736 |
CD1 |
O |
|
| LEU | B:269 | B:269 | 57.0 | 0.335 | E | -123.7 | 133.8 | NA | NA | NA | |||||||||||||
| LEU | C:269 | C:269 | 58.0 | 0.341 | E | -133.9 | 140.2 | NA | NA | NA | |||||||||||||
| LEU | D:269 | D:269 | 54.0 | 0.318 | E | -126.7 | 141.0 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | LEU | A:269 | A:269 | 40.0 | 0.235 | E | -118.6 | 139.9 | 40.0 | 0.235 | 0.0 |
HOH |
3.243 |
CD1 |
O |
||
| LEU | B:269 | B:269 | 40.0 | 0.235 | E | -117.2 | 132.2 | NA | NA | NA | |||||||||||||
| LEU | C:269 | C:269 | 56.0 | 0.329 | E | -129.1 | 133.4 | NA | NA | NA | |||||||||||||
| LEU | D:269 | D:269 | 42.0 | 0.247 | E | -103.4 | 131.4 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | LEU | A:269 | I:269 | 48.0 | 0.282 | E | -134.5 | 143.3 | 40.0 | 0.235 | 0.047 |
B:Q5SWW8:0.047 |
HOH |
4.011 |
CD1 |
O |
|
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | LEU | A:269 | A:269 | 52.0 | 0.306 | E | -122.2 | 145.9 | 52.0 | 0.306 | 0.0 | ||||||
| LEU | B:269 | B:269 | 56.0 | 0.329 | E | -125.3 | 137.2 | NA | NA | NA | |||||||||||||
| LEU | C:269 | C:269 | 53.0 | 0.312 | E | -140.7 | 145.2 | NA | NA | NA | |||||||||||||
| LEU | D:269 | D:269 | 52.0 | 0.306 | E | -105.3 | 143.9 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | LEU | A:269 | A:269 | 62.0 | 0.365 | E | -129.0 | 141.0 | 62.0 | 0.365 | 0.0 |
HOH |
4.309 |
CD1 |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | LEU | A:269 | A:269 | 54.0 | 0.318 | E | -141.7 | 144.2 | 54.0 | 0.318 | 0.0 |
HOH |
6.472 |
CD1 |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | LEU | A:269 | A:269 | 59.0 | 0.347 | E | -127.4 | 145.7 | 59.0 | 0.347 | 0.0 |
HOH |
7.362 |
N |
O |
||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | LEU | A:269 | A:269 | 75.0 | 0.441 | E | -123.2 | 139.5 | 75.0 | 0.441 | 0.0 |
HOH |
3.379 |
CD1 |
O |
||
| LEU | B:269 | B:269 | 40.0 | 0.235 | E | -125.7 | 143.4 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | LEU | A:267 | A:269 | 57.0 | 0.335 | E | -124.3 | 144.2 | 57.0 | 0.335 | 0.0 | ||||||
| LEU | B:267 | B:269 | 57.0 | 0.335 | E | -130.2 | 141.3 | 57.0 | 0.335 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | LEU | A:266 | A:269 | 51.0 | 0.3 | E | -134.4 | 139.1 | 51.0 | 0.3 | 0.0 |
HOH |
3.696 |
CD2 |
O |
||
| LEU | B:266 | B:269 | 48.0 | 0.282 | E | -121.2 | 136.5 | NA | NA | NA | |||||||||||||
| LEU | C:266 | C:269 | 51.0 | 0.3 | E | -129.0 | 139.6 | NA | NA | NA | |||||||||||||
| LEU | D:266 | D:269 | 50.0 | 0.294 | E | -128.3 | 138.3 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | LEU | A:266 | A:269 | 53.0 | 0.312 | E | -125.3 | 141.0 | 53.0 | 0.312 | 0.0 |
HOH |
4.692 |
CD1 |
O |
||
| LEU | B:266 | B:269 | 49.0 | 0.288 | E | -122.4 | 142.1 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | LEU | A:265 | A:269 | 53.0 | 0.312 | E | -129.6 | 141.9 | 53.0 | 0.312 | 0.0 | ||||||
| LEU | B:265 | B:269 | 56.0 | 0.329 | E | -129.4 | 150.8 | NA | NA | NA | |||||||||||||
| LEU | C:265 | C:269 | 65.0 | 0.382 | E | -122.3 | 143.6 | NA | NA | NA | |||||||||||||
| LEU | D:265 | D:269 | 58.0 | 0.341 | E | -126.6 | 138.6 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | LEU | A:264 | I:269 | 45.0 | 0.265 | E | -113.1 | 145.5 | 21.0 | 0.124 | 0.141 |
B:P00750:0.141 |
|||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | LEU | A:269 | A:287 | 63.0 | 0.371 | E | -114.2 | 146.3 | 63.0 | 0.371 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | LEU | A:269 | A:269 | 70.0 | 0.412 | E | -153.8 | 150.8 | 70.0 | 0.412 | 0.0 |
HOH |
6.886 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | LEU | A:292 | A:292 | 53.0 | 0.312 | E | -122.5 | 145.0 | |