Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100778825 | . | G | A | CCDS5711.1:NM_000602.4:c.950gGa>gAa_NP_000593.1:p.317G>E | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | GLY | A:317 | A:317 | 36.0 | 0.48 | T | 120.5 | 6.4 | 36.0 | 0.48 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | GLY | A:294 | A:294 | 34.0 | 0.453 | T | 103.5 | -4.7 | 34.0 | 0.453 | 0.0 |
HOH |
2.991 |
O |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | GLY | A:294 | A:294 | 37.0 | 0.493 | T | 108.0 | -11.6 | 37.0 | 0.493 | 0.0 |
HOH |
2.843 |
O |
O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | GLY | A:298 | A:294 | 34.0 | 0.453 | T | 108.0 | -10.0 | 34.0 | 0.453 | 0.0 |
HOH |
4.697 |
O |
O |
||
| GLY | B:298 | B:294 | 35.0 | 0.467 | T | 107.6 | -5.6 | NA | NA | NA | |||||||||||||
| GLY | C:298 | C:294 | 34.0 | 0.453 | T | 92.7 | 0.7 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | GLY | A:294 | A:294 | 35.0 | 0.467 | T | 95.1 | 0.6 | 35.0 | 0.467 | 0.0 |
HOH |
2.652 |
O |
O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | GLY | A:294 | A:294 | 34.0 | 0.453 | T | 108.6 | -27.7 | 34.0 | 0.453 | 0.0 |
HOH |
3.337 |
CA |
O |
||
| GLY | B:294 | B:294 | 39.0 | 0.52 | T | 84.0 | 16.3 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | GLY | A:294 | A:294 | 37.0 | 0.493 | T | 97.0 | -4.0 | 37.0 | 0.493 | 0.0 |
HOH |
3.322 |
CA |
O |
||
| GLY | B:294 | B:294 | 33.0 | 0.44 | T | 109.1 | -28.3 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | GLY | A:294 | A:294 | 37.0 | 0.493 | T | 100.0 | -3.8 | 37.0 | 0.493 | 0.0 |
HOH |
3.313 |
CA |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | GLY | A:294 | A:294 | 36.0 | 0.48 | T | 98.3 | -1.2 | 36.0 | 0.48 | 0.0 |
HOH |
2.977 |
O |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | GLY | A:294 | A:294 | 36.0 | 0.48 | T | 93.7 | -4.1 | 36.0 | 0.48 | 0.0 |
HOH |
8.916 |
O |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | GLY | A:294 | A:317 | 34.0 | 0.453 | T | 109.4 | -12.7 | 34.0 | 0.453 | 0.0 | ||||||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | GLY | A:307 | A:294 | 32.0 | 0.427 | T | 113.5 | 9.1 | 32.0 | 0.427 | 0.0 |
HOH |
2.578 |
HA3 |
O |
||
| GLY | B:307 | B:294 | 37.0 | 0.493 | T | 111.2 | -2.4 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | GLY | A:294 | A:294 | 36.0 | 0.48 | T | 100.7 | -35.5 | 36.0 | 0.48 | 0.0 | ||||||
| GLY | B:294 | B:294 | 36.0 | 0.48 | T | 102.6 | -37.3 | NA | NA | NA | |||||||||||||
| GLY | C:294 | C:294 | 36.0 | 0.48 | T | 100.8 | -36.2 | NA | NA | NA | |||||||||||||
| GLY | D:294 | D:294 | 35.0 | 0.467 | T | 102.2 | -37.5 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | GLY | A:294 | A:294 | 34.0 | 0.453 | T | 97.1 | -1.5 | 34.0 | 0.453 | 0.0 |
HOH |
3.285 |
CA |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:294 | I:294 | 37.0 | 0.493 | T | 94.0 | 39.1 | 37.0 | 0.493 | 0.0 |
HOH |
9.772 |
O |
O |
||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | GLY | A:294 | A:294 | 41.0 | 0.547 | T | 75.9 | 7.6 | 41.0 | 0.547 | 0.0 | ||||||
| GLY | B:294 | B:294 | 34.0 | 0.453 | T | 114.7 | -15.4 | NA | NA | NA | |||||||||||||
| GLY | C:294 | C:294 | 39.0 | 0.52 | T | 89.1 | -4.8 | NA | NA | NA | |||||||||||||
| GLY | D:294 | D:294 | 36.0 | 0.48 | T | 111.1 | -9.2 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | GLY | A:294 | A:294 | 39.0 | 0.52 | T | 101.5 | 6.8 | 39.0 | 0.52 | 0.0 |
HOH |
2.842 |
O |
O |
||
| GLY | B:294 | B:294 | 36.0 | 0.48 | T | 84.5 | -2.3 | NA | NA | NA | |||||||||||||
| GLY | C:294 | C:294 | 35.0 | 0.467 | T | 94.8 | -10.3 | NA | NA | NA | |||||||||||||
| GLY | D:294 | D:294 | 38.0 | 0.507 | T | 100.0 | 3.8 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | GLY | A:294 | I:294 | 36.0 | 0.48 | T | 104.2 | -0.5 | 36.0 | 0.48 | 0.0 |
HOH |
2.756 |
O |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | GLY | A:294 | A:294 | 34.0 | 0.453 | T | 97.6 | 3.1 | 34.0 | 0.453 | 0.0 | ||||||
| GLY | B:294 | B:294 | 36.0 | 0.48 | T | 93.9 | -14.1 | NA | NA | NA | |||||||||||||
| GLY | C:294 | C:294 | 38.0 | 0.507 | T | 92.9 | 4.7 | NA | NA | NA | |||||||||||||
| GLY | D:294 | D:294 | 35.0 | 0.467 | T | 106.0 | -10.9 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | GLY | A:294 | A:294 | 38.0 | 0.507 | T | 91.2 | -3.2 | 38.0 | 0.507 | 0.0 |
HOH |
3.958 |
CA |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | GLY | A:294 | A:294 | 36.0 | 0.48 | T | 101.5 | -5.1 | 36.0 | 0.48 | 0.0 |
HOH |
2.494 |
O |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | GLY | A:294 | A:294 | 35.0 | 0.467 | T | 104.8 | -4.9 | 35.0 | 0.467 | 0.0 | ||||||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | GLY | A:294 | A:294 | 35.0 | 0.467 | T | 100.4 | -0.5 | 35.0 | 0.467 | 0.0 |
HOH |
2.817 |
O |
O |
||
| GLY | B:294 | B:294 | 36.0 | 0.48 | T | 104.4 | -0.7 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | GLY | A:292 | A:294 | 36.0 | 0.48 | T | 97.7 | 4.4 | 36.0 | 0.48 | 0.0 | ||||||
| GLY | B:292 | B:294 | 35.0 | 0.467 | T | 100.8 | -1.4 | 35.0 | 0.467 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | GLY | A:291 | A:294 | 34.0 | 0.453 | T | 119.3 | -23.8 | 34.0 | 0.453 | 0.0 |
HOH |
5.142 |
O |
O |
||
| GLY | B:291 | B:294 | 34.0 | 0.453 | T | 111.2 | -30.2 | NA | NA | NA | |||||||||||||
| GLY | C:291 | C:294 | 38.0 | 0.507 | T | 109.9 | 1.6 | NA | NA | NA | |||||||||||||
| GLY | D:291 | D:294 | 36.0 | 0.48 | T | 110.4 | -23.2 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | GLY | A:291 | A:294 | 35.0 | 0.467 | T | 89.7 | 2.5 | 35.0 | 0.467 | 0.0 |
HOH |
2.653 |
O |
O |
||
| GLY | B:291 | B:294 | 37.0 | 0.493 | T | 102.4 | -1.4 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | GLY | A:290 | A:294 | 39.0 | 0.52 | T | 109.6 | -13.9 | 39.0 | 0.52 | 0.0 | ||||||
| GLY | B:290 | B:294 | 36.0 | 0.48 | T | 99.4 | -10.4 | NA | NA | NA | |||||||||||||
| GLY | C:290 | C:294 | 35.0 | 0.467 | T | 112.6 | -5.7 | NA | NA | NA | |||||||||||||
| GLY | D:290 | D:294 | 36.0 | 0.48 | T | 92.5 | -9.7 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | GLY | A:289 | I:294 | 47.0 | 0.627 | T | 99.7 | 42.2 | 47.0 | 0.627 | 0.0 | ||||||
| 9pai | 1 | P05121 | 99.71 | 0.0 |
X-RAY |
1999-03-19 | GLY | A:294 | A:312 | 36.0 | 0.48 | T | 109.3 | -24.7 | 36.0 | 0.48 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | GLY | A:294 | A:294 | 39.0 | 0.52 | T | 97.4 | 17.7 | 39.0 | 0.52 | 0.0 |
HOH |
2.875 |
O |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | GLY | A:317 | A:317 | 38.0 | 0.507 | T | 90.6 | 1.0 | |