Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100778843 . G A CCDS5711.1:NM_000602.4:c.968aGa>aAa_NP_000593.1:p.323R>K Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 ARG A:323 A:323 103.0 0.458 S -91.8 115.4 103.0 0.458 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 ARG A:300 A:300 85.0 0.378 S -95.8 117.8 85.0 0.378 0.0 HOH
 2.957
 NH1
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 ARG A:300 A:300 111.0 0.493 -102.6 116.2 111.0 0.493 0.0 HOH
 2.483
 NH1
 O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 ARG A:304 A:300 88.0 0.391 S -106.4 120.3 88.0 0.391 0.0 HOH
 3.894
 CA
 O
ARG B:304 B:300 99.0 0.44 -98.4 132.3 NA NA NA
ARG C:304 C:300 113.0 0.502 S -90.8 144.3 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 ARG A:300 A:300 95.0 0.422 -97.2 123.1 95.0 0.422 0.0 HOH
 7.457
 O
 O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 ARG A:300 A:300 93.0 0.413 S -97.9 121.5 93.0 0.413 0.0 HOH
 2.695
 NE
 O
ARG B:300 B:300 87.0 0.387 -106.5 118.7 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 ARG A:300 A:300 93.0 0.413 S -95.6 122.8 93.0 0.413 0.0 HOH
 3.270
 NE
 O
ARG B:300 B:300 89.0 0.396 S -87.1 120.5 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 ARG A:300 A:300 74.0 0.329 S -114.2 119.8 27.0 0.12 0.209 C:None:0.209
 HOH
 3.469
 CG
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 ARG A:300 A:300 49.0 NA S -104.9 119.7 49.0 NA NA HOH
 3.534
 CG
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 ARG A:300 A:300 84.0 0.373 S -107.4 126.7 35.0 0.156 0.217 C:None:0.218
 HOH
 3.452
 CB
 O
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 ARG A:300 A:323 92.0 0.409 -112.9 108.5 92.0 0.409 0.0 HOH
 5.159
 N
 O
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 ARG A:313 A:300 118.0 0.524 -99.7 112.4 118.0 0.524 0.0 HOH
 2.747
 HE
 O
ARG B:313 B:300 118.0 0.524 -91.5 112.1 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 ARG A:300 A:300 97.0 0.431 S -93.5 123.9 97.0 0.431 0.0
ARG B:300 B:300 98.0 0.436 -92.0 123.7 NA NA NA
ARG C:300 C:300 98.0 0.436 S -92.8 123.8 NA NA NA
ARG D:300 D:300 97.0 0.431 -92.9 124.0 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 ARG A:300 A:300 136.0 0.604 S -95.4 114.7 136.0 0.604 0.0 HOH
 3.256
 CD
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 ARG A:300 I:300 118.0 0.524 -97.4 134.4 118.0 0.524 0.0 HOH
 7.983
 C
 O
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 ARG A:300 A:300 112.0 0.498 S -88.3 134.9 112.0 0.498 0.0
ARG B:300 B:300 125.0 0.556 S -83.0 125.9 NA NA NA
ARG C:300 C:300 101.0 0.449 S -82.0 142.4 NA NA NA
ARG D:300 D:300 96.0 0.427 S -84.3 144.1 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 ARG A:300 A:300 121.0 0.538 -110.1 132.7 121.0 0.538 0.0 HOH
 2.803
 NH2
 O
ARG B:300 B:300 102.0 0.453 -100.7 121.3 NA NA NA
ARG C:300 C:300 83.0 0.369 -85.9 117.7 NA NA NA
ARG D:300 D:300 134.0 0.596 -99.8 129.6 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 ARG A:300 I:300 89.0 0.396 S -95.8 119.8 89.0 0.396 0.0 HOH
 3.980
 CG
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 ARG A:300 A:300 91.0 0.404 S -110.0 121.3 91.0 0.404 0.0
ARG B:300 B:300 61.0 0.271 -107.7 124.7 NA NA NA
ARG C:300 C:300 107.0 0.476 -117.4 116.5 NA NA NA
ARG D:300 D:300 97.0 0.431 -107.5 117.0 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 ARG A:300 A:300 110.0 0.489 S -97.7 121.1 110.0 0.489 0.0 HOH
 5.387
 N
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 ARG A:300 A:300 67.0 0.298 S -114.5 124.9 25.0 0.111 0.187 C:None:0.187
 HOH
 3.258
 CD
 O
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 ARG A:300 A:300 73.0 0.324 S -117.0 125.2 73.0 0.324 0.0 HOH
 9.968
 NH1
 O
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 ARG A:300 A:300 64.0 NA S -113.4 118.9 64.0 NA NA HOH
 3.510
 CD
 O
ARG B:300 B:300 70.0 0.311 -123.6 117.8 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 ARG A:298 A:300 92.0 0.409 S -88.5 129.6 92.0 0.409 0.0
ARG B:298 B:300 91.0 0.404 S -92.2 127.4 91.0 0.404 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 ARG A:297 A:300 76.0 0.338 S -75.1 129.8 76.0 0.338 0.0 HOH
 6.869
 CB
 O
ARG B:297 B:300 87.0 0.387 -85.7 127.4 NA NA NA
ARG C:297 C:300 137.0 0.609 S -76.2 138.3 NA NA NA
ARG D:297 D:300 155.0 0.689 S -71.7 136.2 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 ARG A:297 A:300 74.0 0.329 S -101.2 123.2 74.0 0.329 0.0 HOH
 5.380
 N
 O
ARG B:297 B:300 93.0 0.413 S -113.7 119.4 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 ARG A:296 A:300 94.0 0.418 S -111.9 120.6 94.0 0.418 0.0
ARG B:296 B:300 80.0 0.356 S -97.1 118.2 NA NA NA
ARG C:296 C:300 96.0 0.427 -108.4 118.8 NA NA NA
ARG D:296 D:300 85.0 0.378 -106.2 115.3 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 ARG A:295 I:300 27.0 NA S -144.8 44.7 27.0 NA NA
9pai 1 P05121 99.71 0.0 X-RAY
 1999-03-19 ARG A:300 A:318 107.0 0.476 S -80.1 128.6 107.0 0.476 0.0
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 SER A:300 A:300 27.0 0.235 -102.2 124.0 27.0 0.235 0.0 HOH
 2.552
 OG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 ARG A:323 A:323 110.0 0.489 -112.9 114.0