Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100780320 | . | A | C | CCDS5711.1:NM_000602.4:c.1126Atc>Ctc_NP_000593.1:p.376I>L | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | ILE | A:376 | A:376 | 73.0 | 0.417 | -140.3 | 144.1 | 73.0 | 0.417 | 0.0 | |||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | ILE | A:353 | A:353 | 71.0 | 0.406 | -100.3 | 135.1 | 71.0 | 0.406 | 0.0 |
HOH |
2.912 |
N |
O |
|||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | ILE | A:353 | A:353 | 76.0 | 0.434 | -116.8 | 139.8 | 76.0 | 0.434 | 0.0 |
DMS HOH |
4.565 3.020 |
CG1 N |
C2 O |
|||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | ILE | A:357 | A:353 | 95.0 | 0.543 | -110.6 | 141.1 | 95.0 | 0.543 | 0.0 |
HOH |
3.041 |
N |
O |
|||
| ILE | B:357 | B:353 | 90.0 | 0.514 | -114.5 | 140.7 | NA | NA | NA | ||||||||||||||
| ILE | C:357 | C:353 | 103.0 | 0.589 | -136.6 | 135.5 | NA | NA | NA | ||||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | ILE | A:353 | A:353 | 55.0 | 0.314 | E | -111.1 | 118.0 | 55.0 | 0.314 | 0.0 |
HOH |
2.761 |
N |
O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ILE | A:353 | A:353 | 51.0 | 0.291 | E | -108.0 | 119.8 | 51.0 | 0.291 | 0.0 |
HOH |
3.059 |
O |
O |
||
| ILE | B:353 | B:353 | 39.0 | 0.223 | E | -108.0 | 121.4 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | ILE | A:353 | A:353 | 38.0 | 0.217 | E | -114.9 | 109.4 | 38.0 | 0.217 | 0.0 |
HOH |
3.143 |
O |
O |
||
| ILE | B:353 | B:353 | 32.0 | 0.183 | E | -117.4 | 110.5 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | ILE | A:353 | A:353 | 36.0 | 0.206 | E | -112.4 | 116.7 | 36.0 | 0.206 | 0.0 | ||||||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | ILE | A:353 | A:353 | 36.0 | 0.206 | E | -109.8 | 117.5 | 36.0 | 0.206 | 0.0 |
HOH |
2.805 |
N |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | ILE | A:353 | A:353 | 45.0 | 0.257 | E | -105.2 | 113.8 | 45.0 | 0.257 | 0.0 | ||||||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | ILE | A:353 | A:376 | 53.0 | 0.303 | E | -114.5 | 111.6 | 53.0 | 0.303 | 0.0 | ||||||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | ILE | A:366 | A:353 | 37.0 | 0.211 | E | -99.6 | 117.1 | 37.0 | 0.211 | 0.0 |
HOH |
2.078 |
H |
O |
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| ILE | B:366 | B:353 | 40.0 | 0.229 | E | -111.4 | 113.5 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | ILE | A:353 | A:353 | 38.0 | 0.217 | E | -107.7 | 109.9 | 38.0 | 0.217 | 0.0 | ||||||
| ILE | B:353 | B:353 | 41.0 | 0.234 | E | -107.4 | 111.3 | NA | NA | NA | |||||||||||||
| ILE | C:353 | C:353 | 41.0 | 0.234 | E | -107.8 | 109.8 | NA | NA | NA | |||||||||||||
| ILE | D:353 | D:353 | 39.0 | 0.223 | E | -108.0 | 110.7 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | ILE | A:353 | A:353 | 58.0 | 0.331 | E | -116.3 | 115.9 | 58.0 | 0.331 | 0.0 |
HOH |
3.714 |
CD1 |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:353 | I:353 | 39.0 | 0.223 | E | -106.3 | 138.9 | 39.0 | 0.223 | 0.0 |
GOL HOH |
7.461 7.247 |
CD1 CG1 |
O3 O |
||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | ILE | A:353 | A:353 | 42.0 | 0.24 | E | -112.6 | 120.0 | 42.0 | 0.24 | 0.0 |
HOH |
8.220 |
N |
O |
||
| ILE | B:353 | B:353 | 44.0 | 0.251 | E | -102.4 | 118.5 | NA | NA | NA | |||||||||||||
| ILE | C:353 | C:353 | 47.0 | 0.269 | E | -112.8 | 114.1 | NA | NA | NA | |||||||||||||
| ILE | D:353 | D:353 | 45.0 | 0.257 | E | -106.4 | 116.6 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | ILE | A:353 | A:353 | 37.0 | 0.211 | E | -92.4 | 124.5 | 37.0 | 0.211 | 0.0 |
HOH |
3.308 |
N |
O |
||
| ILE | B:353 | B:353 | 71.0 | 0.406 | E | -120.7 | 122.2 | NA | NA | NA | |||||||||||||
| ILE | C:353 | C:353 | 45.0 | 0.257 | E | -106.6 | 106.7 | NA | NA | NA | |||||||||||||
| ILE | D:353 | D:353 | 18.0 | 0.103 | E | -100.7 | 113.8 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | ILE | A:353 | I:353 | 42.0 | 0.24 | E | -106.8 | 118.7 | 42.0 | 0.24 | 0.0 |
HOH |
3.214 |
N |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | ILE | A:353 | A:353 | 34.0 | 0.194 | E | -98.5 | 118.6 | 34.0 | 0.194 | 0.0 | ||||||
| ILE | B:353 | B:353 | 46.0 | 0.263 | E | -113.0 | 102.6 | NA | NA | NA | |||||||||||||
| ILE | C:353 | C:353 | 37.0 | 0.211 | E | -104.4 | 112.0 | NA | NA | NA | |||||||||||||
| ILE | D:353 | D:353 | 42.0 | 0.24 | E | -113.7 | 109.7 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | ILE | A:353 | A:353 | 46.0 | 0.263 | E | -102.4 | 115.7 | 46.0 | 0.263 | 0.0 |
HOH |
2.609 |
O |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ILE | A:353 | A:353 | 49.0 | 0.28 | E | -110.1 | 120.1 | 49.0 | 0.28 | 0.0 |
HOH |
2.765 |
O |
O |
||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | ILE | A:353 | A:353 | 23.0 | 0.131 | E | -104.1 | 109.5 | 23.0 | 0.131 | 0.0 | ||||||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | ILE | A:353 | A:353 | 61.0 | 0.349 | E | -109.4 | 114.1 | 61.0 | 0.349 | 0.0 |
HOH |
2.868 |
N |
O |
||
| ILE | B:353 | B:353 | 39.0 | 0.223 | E | -114.4 | 110.4 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | ILE | A:351 | A:353 | 43.0 | 0.246 | E | -107.5 | 110.2 | 43.0 | 0.246 | 0.0 | ||||||
| ILE | B:351 | B:353 | 43.0 | 0.246 | E | -114.6 | 110.3 | 43.0 | 0.246 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ILE | A:350 | A:353 | 50.0 | 0.286 | E | -99.7 | 116.8 | 50.0 | 0.286 | 0.0 |
HOH |
6.476 |
O |
O |
||
| ILE | B:350 | B:353 | 43.0 | 0.246 | E | -96.6 | 116.7 | NA | NA | NA | |||||||||||||
| ILE | C:350 | C:353 | 41.0 | 0.234 | E | -105.5 | 111.5 | NA | NA | NA | |||||||||||||
| ILE | D:350 | D:353 | 43.0 | 0.246 | E | -113.5 | 126.2 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | ILE | A:350 | A:353 | 35.0 | 0.2 | E | -104.5 | 119.0 | 35.0 | 0.2 | 0.0 |
HOH |
2.949 |
N |
O |
||
| ILE | B:350 | B:353 | 34.0 | 0.194 | E | -102.4 | 110.8 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | ILE | A:349 | A:353 | 28.0 | 0.16 | E | -100.1 | 108.3 | 28.0 | 0.16 | 0.0 | ||||||
| ILE | B:349 | B:353 | 33.0 | 0.189 | E | -106.3 | 113.9 | NA | NA | NA | |||||||||||||
| ILE | C:349 | C:353 | 29.0 | 0.166 | E | -102.1 | 107.9 | NA | NA | NA | |||||||||||||
| ILE | D:349 | D:353 | 34.0 | 0.194 | E | -107.4 | 112.0 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | ILE | A:348 | I:353 | 48.0 | 0.274 | E | -107.9 | 125.9 | 48.0 | 0.274 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | VAL | A:353 | A:353 | 53.0 | 0.342 | -102.7 | 139.2 | 53.0 | 0.342 | 0.0 |
HOH |
4.703 |
O |
O |
|||
| 9pai | 2 | P05121 | 100.0 | 6e-16 |
X-RAY |
1999-03-19 | ILE | B:7 | B:371 | 85.0 | 0.486 | -99.4 | 139.2 | 22.0 | 0.126 | 0.36 |
A:P05121:0.36 |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | ILE | A:376 | A:376 | 47.0 | 0.269 | E | -104.7 | 119.2 | |