Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100780350 . C A CCDS5711.1:NM_000602.4:c.1156Cgg>Agg_NP_000593.1:p.386R>R Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 ARG A:386 A:386 21.0 0.093 E -127.2 150.0 21.0 0.093 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 ARG A:363 A:363 12.0 0.053 E -138.2 142.8 12.0 0.053 0.0 HOH
 2.722
 NE
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 ARG A:363 A:363 22.0 0.098 E -134.5 142.0 22.0 0.098 0.0 DMS
HOH
 4.937
2.893
 NH2
NH1
 C1
O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 ARG A:367 A:363 13.0 0.058 E -135.4 126.4 13.0 0.058 0.0 HOH
 4.445
 NH2
 O
ARG B:367 B:363 13.0 0.058 E -138.8 137.9 NA NA NA
ARG C:367 C:363 13.0 0.058 E -115.9 137.3 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 ARG A:363 A:363 20.0 0.089 E -131.6 140.3 20.0 0.089 0.0 NAG
NAG
HOH
 8.895
8.860
2.919
 NH2
NH1
NE
 O7
O6
O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 ARG A:363 A:363 14.0 0.062 E -123.3 135.9 14.0 0.062 0.0 HOH
 2.935
 NE
 O
ARG B:363 B:363 17.0 0.076 E -132.7 129.8 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 ARG A:363 A:363 17.0 0.076 E -131.8 134.3 17.0 0.076 0.0 ZN
HOH
 9.056
2.833
 NH2
NE
 ZN
O
ARG B:363 B:363 13.0 0.058 E -111.9 138.4 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 ARG A:363 A:363 15.0 0.067 E -131.2 141.5 15.0 0.067 0.0 HOH
 4.812
 NH2
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 ARG A:363 A:363 16.0 0.071 E -122.6 138.3 16.0 0.071 0.0 HOH
 2.769
 NE
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 ARG A:363 A:363 17.0 0.076 E -136.8 135.9 17.0 0.076 0.0 HOH
 4.694
 NH2
 O
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 ARG A:363 A:386 19.0 0.084 E -112.3 140.7 19.0 0.084 0.0 NAG
 6.071
 NH2
 O6
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 ARG A:376 A:363 20.0 0.089 E -128.8 136.2 20.0 0.089 0.0 HOH
 1.986
 HE
 O
ARG B:376 B:363 18.0 0.08 E -136.8 137.7 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 ARG A:363 A:363 12.0 0.053 E -124.3 150.1 12.0 0.053 0.0
ARG B:363 B:363 12.0 0.053 E -125.9 150.3 NA NA NA
ARG C:363 C:363 12.0 0.053 E -123.1 149.9 NA NA NA
ARG D:363 D:363 13.0 0.058 E -123.9 150.2 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 ARG A:363 A:363 22.0 0.098 E -109.9 134.9 22.0 0.098 0.0 HOH
 3.496
 NE
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 ARG A:363 I:363 25.0 0.111 E -136.7 155.4 25.0 0.111 0.0 HOH
 5.788
 NH2
 O
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 ARG A:363 A:363 18.0 0.08 E -114.1 139.6 18.0 0.08 0.0
ARG B:363 B:363 17.0 0.076 E -120.2 137.7 NA NA NA
ARG C:363 C:363 22.0 0.098 E -114.4 144.7 NA NA NA
ARG D:363 D:363 18.0 0.08 E -112.7 143.6 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 ARG A:363 A:363 14.0 0.062 E -131.6 145.4 14.0 0.062 0.0 HOH
 2.796
 NH1
 O
ARG B:363 B:363 20.0 0.089 E -129.4 160.6 NA NA NA
ARG C:363 C:363 22.0 0.098 E -121.9 144.4 NA NA NA
ARG D:363 D:363 17.0 0.076 E -128.9 153.0 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 ARG A:363 I:363 23.0 0.102 E -126.0 151.4 23.0 0.102 0.0 HOH
 3.127
 NH2
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 ARG A:363 A:363 23.0 0.102 E -121.0 151.1 23.0 0.102 0.0
ARG B:363 B:363 25.0 0.111 E -116.3 155.9 NA NA NA
ARG C:363 C:363 29.0 0.129 E -121.8 146.1 NA NA NA
ARG D:363 D:363 27.0 0.12 E -117.6 153.6 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 ARG A:363 A:363 17.0 0.076 E -121.4 142.0 17.0 0.076 0.0 HOH
 5.621
 NH1
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 ARG A:363 A:363 17.0 0.076 E -134.3 125.9 17.0 0.076 0.0
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 ARG A:363 A:363 17.0 0.076 E -127.2 134.2 17.0 0.076 0.0
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 ARG A:363 A:363 7.0 0.031 E -127.4 136.0 7.0 0.031 0.0 HOH
 2.878
 NE
 O
ARG B:363 B:363 29.0 0.129 E -117.2 135.0 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 ARG A:361 A:363 22.0 0.098 E -120.1 145.2 22.0 0.098 0.0
ARG B:361 B:363 22.0 0.098 E -120.3 148.5 22.0 0.098 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 ARG A:360 A:363 25.0 0.111 E -105.1 140.2 25.0 0.111 0.0
ARG B:360 B:363 30.0 0.133 E -120.8 138.5 NA NA NA
ARG C:360 C:363 28.0 0.124 E -114.3 138.9 NA NA NA
ARG D:360 D:363 40.0 0.178 E -108.7 139.8 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 ARG A:360 A:363 23.0 0.102 E -121.9 137.3 23.0 0.102 0.0 HOH
 2.991
 NE
 O
ARG B:360 B:363 34.0 0.151 E -113.8 136.4 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 ARG A:359 A:363 16.0 0.071 E -120.5 141.5 16.0 0.071 0.0
ARG B:359 B:363 19.0 0.084 E -131.4 146.2 NA NA NA
ARG C:359 C:363 21.0 0.093 E -114.7 137.6 NA NA NA
ARG D:359 D:363 28.0 0.124 E -117.6 138.9 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 ARG A:358 I:363 20.0 0.089 E -139.0 139.4 20.0 0.089 0.0
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 ARG A:363 A:363 10.0 0.044 E -128.6 133.8 10.0 0.044 0.0 HOH
 2.801
 NH2
 O
9pai 2 P05121 100.0 6e-16 X-RAY
 1999-03-19 ARG B:17 B:381 130.0 0.578 E -140.9 162.3 16.0 0.071 0.507 A:P05121:0.507

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 ARG A:386 A:386 28.0 0.124 E -116.8 139.1