Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 100780359 | . | C | A | CCDS5711.1:NM_000602.4:c.1165Ccc>Acc_NP_000593.1:p.389P>T | Homo sapiens serpin family E member 1 (SERPINE1), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1c5g | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
1999-12-17 | PRO | A:389 | A:389 | 69.0 | 0.476 | T | -53.6 | -46.0 | 69.0 | 0.476 | 0.0 | ||||||
| 1dvn | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2000-09-13 | PRO | A:366 | A:366 | 76.0 | 0.524 | T | -58.3 | -35.9 | 76.0 | 0.524 | 0.0 |
HOH |
3.228 |
O |
O |
||
| 1lj5 | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2002-05-08 | PRO | A:366 | A:366 | 64.0 | 0.441 | T | -59.1 | -26.1 | 64.0 | 0.441 | 0.0 |
DMS HOH |
3.677 2.705 |
O O |
C1 O |
||
| 4aqh | 1 | P05121 | 100.0 | 0.0 |
X-RAY |
2012-11-28 | PRO | A:370 | A:366 | 84.0 | 0.579 | T | -59.1 | -33.9 | 84.0 | 0.579 | 0.0 |
HOH |
3.488 |
O |
O |
||
| PRO | B:370 | B:366 | 84.0 | 0.579 | T | -64.3 | -23.4 | NA | NA | NA | |||||||||||||
| PRO | C:370 | C:366 | 74.0 | 0.51 | T | -55.1 | -42.1 | NA | NA | NA | |||||||||||||
| 1a7c | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
1999-03-23 | PRO | A:366 | A:366 | 74.0 | 0.51 | T | -59.7 | -40.3 | 74.0 | 0.51 | 0.0 |
NAG HOH |
9.734 4.338 |
N CB |
C6 O |
||
| 3q02 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | PRO | A:366 | A:366 | 89.0 | 0.614 | T | -58.9 | -33.8 | 89.0 | 0.614 | 0.0 |
HOH |
9.422 |
N |
O |
||
| PRO | B:366 | B:366 | 64.0 | 0.441 | T | -62.7 | -39.2 | NA | NA | NA | |||||||||||||
| 3q03 | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2011-06-22 | PRO | A:366 | A:366 | 79.0 | 0.545 | T | -52.9 | -38.0 | 79.0 | 0.545 | 0.0 |
HOH |
3.052 |
O |
O |
||
| PRO | B:366 | B:366 | 67.0 | 0.462 | T | -54.8 | -44.2 | NA | NA | NA | |||||||||||||
| 6gwn | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-01-01 | PRO | A:366 | A:366 | 93.0 | 0.641 | T | -69.0 | -43.0 | 93.0 | 0.641 | 0.0 |
HOH |
5.626 |
CG |
O |
||
| 6zrv | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2020-08-26 | PRO | A:366 | A:366 | 94.0 | 0.648 | T | -65.2 | -34.0 | 94.0 | 0.648 | 0.0 |
HOH |
5.629 |
O |
O |
||
| 7aqg | 1 | P05121 | 99.74 | 0.0 |
X-RAY |
2021-02-24 | PRO | A:366 | A:366 | 85.0 | 0.586 | T | -59.5 | -38.4 | 85.0 | 0.586 | 0.0 |
HOH |
8.999 |
C |
O |
||
| 3r4l | 1 | P05121 | 99.47 | 0.0 |
X-RAY |
2011-11-02 | PRO | A:366 | A:389 | 87.0 | 0.6 | T | -52.0 | -39.8 | 87.0 | 0.6 | 0.0 |
NAG |
9.236 |
N |
O6 |
||
| 3cvm | 1 | P05121 | 98.69 | 0.0 |
X-RAY |
2008-08-19 | PRO | A:379 | A:366 | 42.0 | 0.29 | T | -63.1 | -30.3 | 42.0 | 0.29 | 0.0 |
HOH |
3.052 |
HB3 |
O |
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| PRO | B:379 | B:366 | 38.0 | 0.262 | T | -65.2 | -22.4 | NA | NA | NA | |||||||||||||
| 1b3k | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
1999-12-11 | PRO | A:366 | A:366 | 78.0 | 0.538 | T | -59.0 | -54.8 | 78.0 | 0.538 | 0.0 | ||||||
| PRO | B:366 | B:366 | 76.0 | 0.524 | T | -58.6 | -55.5 | NA | NA | NA | |||||||||||||
| PRO | C:366 | C:366 | 77.0 | 0.531 | T | -58.7 | -56.2 | NA | NA | NA | |||||||||||||
| PRO | D:366 | D:366 | 77.0 | 0.531 | T | -59.0 | -55.4 | NA | NA | NA | |||||||||||||
| 1oc0 | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2003-06-19 | PRO | A:366 | A:366 | 91.0 | 0.628 | T | -65.8 | -26.5 | 91.0 | 0.628 | 0.0 |
HOH |
4.308 |
CG |
O |
||
| 5brr | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:366 | I:366 | 88.0 | 0.607 | T | -56.8 | -41.9 | 88.0 | 0.607 | 0.0 |
HOH |
5.174 |
O |
O |
||
| 6i8s | 1 | P05121 | 98.94 | 0.0 |
X-RAY |
2019-02-13 | PRO | A:366 | A:366 | 84.0 | 0.579 | T | -64.3 | -24.1 | 84.0 | 0.579 | 0.0 | ||||||
| PRO | B:366 | B:366 | 78.0 | 0.538 | T | -62.7 | -31.7 | NA | NA | NA | |||||||||||||
| PRO | C:366 | C:366 | 76.0 | 0.524 | T | -64.4 | -21.3 | NA | NA | NA | |||||||||||||
| PRO | D:366 | D:366 | 77.0 | 0.531 | T | -69.8 | -20.8 | NA | NA | NA | |||||||||||||
| 1dvm | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2000-09-06 | PRO | A:366 | A:366 | 77.0 | 0.531 | T | -59.5 | -36.4 | 77.0 | 0.531 | 0.0 |
HOH |
3.461 |
CG |
O |
||
| PRO | B:366 | B:366 | 88.0 | 0.607 | T | -60.0 | -19.4 | NA | NA | NA | |||||||||||||
| PRO | C:366 | C:366 | 75.0 | 0.517 | T | -76.2 | 2.0 | NA | NA | NA | |||||||||||||
| PRO | D:366 | D:366 | 75.0 | 0.517 | T | -57.3 | -45.4 | NA | NA | NA | |||||||||||||
| 3pb1 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2010-12-29 | PRO | A:366 | I:366 | 79.0 | 0.545 | T | -65.9 | -34.2 | 79.0 | 0.545 | 0.0 |
HOH |
3.445 |
N |
O |
||
| 4ic0 | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2013-12-11 | PRO | A:366 | A:366 | 77.0 | 0.531 | T | -76.4 | -16.1 | 77.0 | 0.531 | 0.0 | ||||||
| PRO | B:366 | B:366 | 81.0 | 0.559 | T | -51.5 | -31.3 | NA | NA | NA | |||||||||||||
| PRO | C:366 | C:366 | 81.0 | 0.559 | T | -67.8 | -24.5 | NA | NA | NA | |||||||||||||
| PRO | D:366 | D:366 | 83.0 | 0.572 | T | -57.4 | -33.1 | NA | NA | NA | |||||||||||||
| 3eox | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2009-02-17 | PRO | A:366 | A:366 | 38.0 | 0.262 | T | -64.5 | -22.6 | 38.0 | 0.262 | 0.0 |
HOH |
2.676 |
O |
O |
||
| 6gwp | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | PRO | A:366 | A:366 | 90.0 | 0.621 | T | -56.7 | -54.6 | 90.0 | 0.621 | 0.0 | ||||||
| 6gwq | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2020-01-01 | PRO | A:366 | A:366 | 69.0 | 0.476 | T | -68.3 | -18.0 | 69.0 | 0.476 | 0.0 | ||||||
| 7aqf | 1 | P05121 | 98.68 | 0.0 |
X-RAY |
2021-02-17 | PRO | A:366 | A:366 | 59.0 | 0.407 | T | -57.9 | -33.8 | 59.0 | 0.407 | 0.0 |
HOH |
2.809 |
O |
O |
||
| PRO | B:366 | B:366 | 93.0 | 0.641 | T | -56.6 | -29.0 | NA | NA | NA | |||||||||||||
| 1db2 | 1 | P05121 | 98.67 | 0.0 |
X-RAY |
1999-11-10 | PRO | A:364 | A:366 | 83.0 | 0.572 | T | -47.4 | -44.8 | 83.0 | 0.572 | 0.0 | ||||||
| PRO | B:364 | B:366 | 79.0 | 0.545 | T | -51.8 | -38.4 | 79.0 | 0.545 | 0.0 | |||||||||||||
| 4g8o | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | PRO | A:363 | A:366 | 83.0 | 0.572 | T | -61.5 | -30.7 | 83.0 | 0.572 | 0.0 | ||||||
| PRO | B:363 | B:366 | 88.0 | 0.607 | T | -65.5 | -31.1 | NA | NA | NA | |||||||||||||
| PRO | C:363 | C:366 | 72.0 | 0.497 | T | -66.8 | -27.0 | NA | NA | NA | |||||||||||||
| PRO | D:363 | D:366 | 72.0 | 0.497 | T | -67.3 | -20.3 | NA | NA | NA | |||||||||||||
| 4g8r | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-12-25 | PRO | A:363 | A:366 | 78.0 | 0.538 | T | -63.9 | -37.4 | 78.0 | 0.538 | 0.0 |
HOH |
4.153 |
O |
O |
||
| PRO | B:363 | B:366 | 82.0 | 0.566 | T | -63.9 | -23.4 | NA | NA | NA | |||||||||||||
| 3ut3 | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2013-02-06 | PRO | A:362 | A:366 | 90.0 | 0.621 | T | -53.9 | -28.7 | 90.0 | 0.621 | 0.0 | ||||||
| PRO | B:362 | B:366 | 79.0 | 0.545 | T | -55.7 | -32.1 | NA | NA | NA | |||||||||||||
| PRO | C:362 | C:366 | 82.0 | 0.566 | T | -62.3 | -27.7 | NA | NA | NA | |||||||||||||
| PRO | D:362 | D:366 | 75.0 | 0.517 | T | -58.8 | -14.6 | NA | NA | NA | |||||||||||||
| 5zlz | 1 | P05121 | 98.93 | 0.0 |
X-RAY |
2019-04-03 | PRO | A:361 | I:366 | 85.0 | 0.586 | T | -62.3 | -12.3 | 85.0 | 0.586 | 0.0 | ||||||
| 3lw2 | 1 | P22777 | 80.75 | 0.0 |
X-RAY |
2010-04-07 | PRO | A:366 | A:366 | 71.0 | 0.49 | T | -53.4 | -37.1 | 71.0 | 0.49 | 0.0 |
HOH |
3.872 |
CG |
O |
||
| 9pai | 2 | P05121 | 100.0 | 6e-16 |
X-RAY |
1999-03-19 | PRO | B:20 | B:384 | 117.0 | 0.807 | T | -49.1 | -48.5 | 72.0 | 0.497 | 0.31 |
A:P05121:0.31 |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05121-f1 | 1 | P05121 | 100.0 | 0.0 | PRO | A:389 | A:389 | 84.0 | 0.579 | T | -62.1 | -41.0 | |