Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 100780714 . G A CCDS5711.1:NM_000602.4:c.1200atG>atA_NP_000593.1:p.400M>I Homo sapiens serpin family E member 1 (SERPINE1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1c5g 1 P05121 100.0 0.0 X-RAY
 1999-12-17 MET A:400 A:400 48.0 0.259 E -65.2 153.2 48.0 0.259 0.0
1dvn 1 P05121 100.0 0.0 X-RAY
 2000-09-13 MET A:377 A:377 19.0 0.103 E -49.7 120.1 19.0 0.103 0.0 HOH
 3.033
 N
 O
1lj5 1 P05121 100.0 0.0 X-RAY
 2002-05-08 MET A:377 A:377 24.0 0.13 E -56.0 133.1 24.0 0.13 0.0 HOH
 2.765
 O
 O
4aqh 1 P05121 100.0 0.0 X-RAY
 2012-11-28 MET A:381 A:377 42.0 0.227 E -50.3 121.5 42.0 0.227 0.0 HOH
 6.065
 O
 O
MET B:381 B:377 33.0 0.178 E -37.7 116.9 NA NA NA
MET C:381 C:377 39.0 0.211 E -43.4 128.3 NA NA NA
1a7c 1 P05121 99.74 0.0 X-RAY
 1999-03-23 MET A:377 A:377 13.0 0.07 S -89.6 -23.3 13.0 0.07 0.0 HOH
 4.281
 CE
 O
3q02 1 P05121 99.74 0.0 X-RAY
 2011-06-22 MET A:377 A:377 8.0 0.043 S -97.6 -25.3 8.0 0.043 0.0 CL
 4.306
 CE
 CL
MET B:377 B:377 11.0 0.059 S -94.9 -26.4 NA NA NA
3q03 1 P05121 99.74 0.0 X-RAY
 2011-06-22 MET A:377 A:377 8.0 0.043 S -86.7 -24.3 8.0 0.043 0.0 CL
HOH
 4.189
4.151
 CE
SD
 CL
O
MET B:377 B:377 11.0 0.059 S -86.0 -29.1 NA NA NA
6gwn 1 P05121 99.74 0.0 X-RAY
 2020-01-01 MET A:377 A:377 10.0 0.054 S -88.4 -29.5 10.0 0.054 0.0 HOH
 2.632
 O
 O
6zrv 1 P05121 99.74 0.0 X-RAY
 2020-08-26 MET A:377 A:377 11.0 0.059 S -94.7 -28.2 11.0 0.059 0.0 HOH
 2.810
 O
 O
7aqg 1 P05121 99.74 0.0 X-RAY
 2021-02-24 MET A:377 A:377 13.0 0.07 S -83.7 -25.1 13.0 0.07 0.0
3r4l 1 P05121 99.47 0.0 X-RAY
 2011-11-02 MET A:377 A:400 13.0 0.07 S -97.3 -50.0 13.0 0.07 0.0 HOH
 3.842
 CE
 O
3cvm 1 P05121 98.69 0.0 X-RAY
 2008-08-19 MET A:390 A:377 11.0 0.059 S -96.3 -25.0 11.0 0.059 0.0 HOH
 2.426
 HE1
 O
MET B:390 B:377 14.0 0.076 S -100.1 -29.8 NA NA NA
1b3k 1 P05121 98.94 0.0 X-RAY
 1999-12-11 MET A:377 A:377 16.0 0.086 S -91.6 -17.3 16.0 0.086 0.0
MET B:377 B:377 16.0 0.086 S -92.2 -16.6 NA NA NA
MET C:377 C:377 16.0 0.086 S -89.9 -18.3 NA NA NA
MET D:377 D:377 16.0 0.086 S -92.1 -18.6 NA NA NA
1oc0 1 P05121 98.94 0.0 X-RAY
 2003-06-19 MET A:377 A:377 17.0 0.092 S -92.8 -29.6 17.0 0.092 0.0 HOH
 2.758
 O
 O
5brr 1 P05121 98.94 0.0 X-RAY
 2015-09-02 MET A:377 I:377 13.0 0.07 S -85.0 -29.7 13.0 0.07 0.0 HOH
 7.276
 CE
 O
6i8s 1 P05121 98.94 0.0 X-RAY
 2019-02-13 MET A:377 A:377 14.0 0.076 S -82.5 -33.9 14.0 0.076 0.0 HOH
 4.284
 CE
 O
MET B:377 B:377 17.0 0.092 S -83.6 -31.7 NA NA NA
MET C:377 C:377 13.0 0.07 S -84.8 -34.6 NA NA NA
MET D:377 D:377 18.0 0.097 S -90.8 -27.9 NA NA NA
1dvm 1 P05121 98.68 0.0 X-RAY
 2000-09-06 MET A:377 A:377 13.0 0.07 S -88.9 -41.3 13.0 0.07 0.0 HOH
 3.064
 O
 O
MET B:377 B:377 13.0 0.07 S -83.0 -12.7 NA NA NA
MET C:377 C:377 13.0 0.07 S -91.1 -12.9 NA NA NA
MET D:377 D:377 9.0 0.049 S -86.9 -29.0 NA NA NA
3pb1 1 P05121 98.68 0.0 X-RAY
 2010-12-29 MET A:377 I:377 12.0 0.065 -85.9 -26.8 12.0 0.065 0.0 HOH
 2.670
 O
 O
4ic0 1 P05121 98.68 0.0 X-RAY
 2013-12-11 MET A:377 A:377 15.0 0.081 -90.7 -38.2 15.0 0.081 0.0
MET B:377 B:377 12.0 0.065 -93.3 -27.5 NA NA NA
MET C:377 C:377 15.0 0.081 -96.1 -32.4 NA NA NA
MET D:377 D:377 12.0 0.065 -71.1 -33.9 NA NA NA
3eox 1 P05121 98.68 0.0 X-RAY
 2009-02-17 MET A:377 A:377 10.0 0.054 S -82.3 -32.6 10.0 0.054 0.0 HOH
 2.790
 O
 O
6gwp 1 P05121 98.68 0.0 X-RAY
 2020-01-01 MET A:377 A:377 12.0 0.065 S -86.6 -21.4 12.0 0.065 0.0 HOH
 2.659
 O
 O
6gwq 1 P05121 98.68 0.0 X-RAY
 2020-01-01 MET A:377 A:377 11.0 0.059 S -88.2 -20.9 11.0 0.059 0.0 HOH
 6.073
 CE
 O
7aqf 1 P05121 98.68 0.0 X-RAY
 2021-02-17 MET A:377 A:377 11.0 0.059 S -88.0 -22.1 11.0 0.059 0.0 HOH
 2.555
 O
 O
MET B:377 B:377 18.0 0.097 S -91.9 -25.5 NA NA NA
1db2 1 P05121 98.67 0.0 X-RAY
 1999-11-10 MET A:375 A:377 18.0 0.097 S -97.0 -24.2 18.0 0.097 0.0
MET B:375 B:377 17.0 0.092 S -85.3 -24.3 17.0 0.092 0.0
4g8o 1 P05121 98.93 0.0 X-RAY
 2013-12-25 MET A:374 A:377 13.0 0.07 S -96.2 -35.1 13.0 0.07 0.0 EDO
HOH
 7.947
2.667
 CB
O
 O1
O
MET B:374 B:377 12.0 0.065 S -97.0 -28.4 NA NA NA
MET C:374 C:377 18.0 0.097 S -85.3 -32.4 NA NA NA
MET D:374 D:377 20.0 0.108 S -92.3 -33.9 NA NA NA
4g8r 1 P05121 98.93 0.0 X-RAY
 2013-12-25 MET A:374 A:377 15.0 0.081 S -91.1 -28.6 15.0 0.081 0.0 HOH
 2.671
 O
 O
MET B:374 B:377 17.0 0.092 S -93.6 -31.7 NA NA NA
3ut3 1 P05121 98.93 0.0 X-RAY
 2013-02-06 MET A:373 A:377 18.0 0.097 S -95.6 -24.1 18.0 0.097 0.0
MET B:373 B:377 15.0 0.081 S -88.0 -13.0 NA NA NA
MET C:373 C:377 18.0 0.097 S -92.5 -34.0 NA NA NA
MET D:373 D:377 13.0 0.07 S -81.7 -20.7 NA NA NA
5zlz 1 P05121 98.93 0.0 X-RAY
 2019-04-03 MET A:372 I:377 3.0 0.016 S -94.0 -32.4 3.0 0.016 0.0
3lw2 1 P22777 80.75 0.0 X-RAY
 2010-04-07 MET A:377 A:377 13.0 0.07 -109.0 128.4 13.0 0.07 0.0 HOH
 3.679
 CB
 O
9pai 2 P05121 100.0 6e-16 X-RAY
 1999-03-19 MET B:31 B:395 121.0 0.654 S -94.7 -25.5 10.0 0.054 0.6 A:P05121:0.6

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05121-f1 1 P05121 100.0 0.0 MET A:400 A:400 11.0 0.059 S -101.9 -26.5