Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107542204 . T A CCDS5749.1:NM_000108.3:c.140aTa>aAa_NP_000099.2:p.47I>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ILE A:33 A:12 8.0 0.046 E -94.8 109.6 8.0 0.046 0.0 FAD
HOH
 3.670
4.987
 CG2
O
 N1A
O
ILE B:33 B:12 8.0 0.046 E -100.8 119.4 8.0 0.046 0.0 FAD
 3.296
 CG2
 N1A
ILE C:33 C:12 9.0 0.051 E -97.5 109.2 NA NA NA
ILE D:33 D:12 8.0 0.046 E -97.4 108.6 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ILE A:12 A:12 9.0 0.051 E -92.3 116.7 9.0 0.051 0.0 FAD
HOH
 3.805
4.959
 CG2
O
 N1A
O
ILE B:12 B:12 10.0 0.057 E -93.1 112.9 10.0 0.057 0.0 FAD
HOH
 3.441
5.030
 CG2
O
 N1A
O
ILE C:12 C:12 10.0 0.057 E -102.0 117.8 NA NA NA
ILE D:12 D:12 11.0 0.063 E -96.5 106.5 NA NA NA
ILE E:12 E:12 8.0 0.046 E -109.2 120.0 NA NA NA
ILE F:12 F:12 10.0 0.057 E -104.8 107.4 NA NA NA
ILE G:12 G:12 8.0 0.046 E -99.1 121.6 NA NA NA
ILE H:12 H:12 6.0 0.034 E -108.3 105.6 NA NA NA
ILE I:12 I:12 13.0 0.074 E -92.3 101.3 NA NA NA
ILE J:12 J:12 7.0 0.04 E -95.0 119.5 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 9.0 0.051 E -100.4 106.9 9.0 0.051 0.0 FAD
BTB
SO4
HOH
 3.088
8.582
9.269
5.044
 HG23
HG22
HD13
HG21
 N1A
HO6
O3
O
ILE B:34 B:12 9.0 0.051 E -99.9 107.4 9.0 0.051 0.0 FAD
BTB
SO4
HOH
 3.042
8.257
9.457
4.953
 HG23
HG22
HD13
O
 N1A
HO8
O2
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 8.0 0.046 E -101.8 105.0 8.0 0.046 0.0 FAD
SO4
HOH
 3.229
9.298
5.084
 HG23
HD12
O
 N1A
O3
O
ILE B:34 B:12 8.0 0.046 E -103.0 105.3 8.0 0.046 0.0 FAD
SO4
HOH
 3.258
9.486
4.928
 HG23
HG21
O
 N1A
O2
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:12 A:12 9.0 0.051 E -101.9 106.1 9.0 0.051 0.0 SO4
FAD
HOH
 9.894
3.679
5.075
 CD1
CG2
O
 O3
N1A
O
ILE B:12 B:12 9.0 0.051 E -98.5 105.4 9.0 0.051 0.0 FAD
HOH
 3.417
5.034
 CG2
O
 N1A
O
ILE C:12 C:12 9.0 0.051 E -93.4 102.1 NA NA NA
ILE D:12 D:12 8.0 0.046 E -99.1 108.8 NA NA NA
ILE E:12 E:12 10.0 0.057 E -96.3 98.8 NA NA NA
ILE F:12 F:12 8.0 0.046 E -96.2 104.0 NA NA NA
ILE G:12 G:12 9.0 0.051 E -100.0 106.0 NA NA NA
ILE H:12 H:12 11.0 0.063 E -104.6 100.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:12 A:12 8.0 0.046 E -99.9 108.3 8.0 0.046 0.0 SO4
FAD
HOH
 9.687
3.637
5.045
 CD1
CG2
O
 O3
N1A
O
ILE B:12 B:12 8.0 0.046 E -97.2 99.2 8.0 0.046 0.0 SO4
FAD
HOH
 9.923
3.371
5.152
 CD1
CG2
O
 O3
N1A
O
ILE C:12 C:12 9.0 0.051 E -94.9 95.5 NA NA NA
ILE D:12 D:12 8.0 0.046 E -101.6 108.7 NA NA NA
ILE E:12 E:12 9.0 0.051 E -95.8 98.4 NA NA NA
ILE F:12 F:12 8.0 0.046 E -100.8 105.2 NA NA NA
ILE G:12 G:12 8.0 0.046 E -101.7 105.3 NA NA NA
ILE H:12 H:12 8.0 0.046 E -97.3 105.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ILE A:12 A:12 8.0 0.046 E -101.2 104.7 8.0 0.046 0.0 SO4
FAD
HOH
 9.972
3.642
4.935
 CD1
CG2
O
 O3
N1A
O
ILE B:12 B:12 9.0 0.051 E -100.4 107.2 9.0 0.051 0.0 FAD
HOH
 3.630
5.146
 CG2
O
 N1A
O
ILE C:12 C:12 8.0 0.046 E -104.0 106.6 NA NA NA
ILE D:12 D:12 8.0 0.046 E -101.0 106.5 NA NA NA
ILE E:12 E:12 7.0 0.04 E -107.8 105.1 NA NA NA
ILE F:12 F:12 6.0 0.034 E -110.4 100.2 NA NA NA
ILE G:12 G:12 8.0 0.046 E -107.7 110.9 NA NA NA
ILE H:12 H:12 7.0 0.04 E -100.3 112.1 NA NA NA
ILE I:12 I:12 8.0 0.046 E -100.1 95.9 NA NA NA
ILE J:12 J:12 6.0 0.034 E -97.6 107.4 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ILE A:33 A:12 9.0 0.051 E -101.7 105.5 9.0 0.051 0.0 FAD
TRS
HOH
 3.217
8.811
4.969
 HG23
HG22
O
 N1A
O3
O
ILE B:33 B:12 8.0 0.046 E -101.5 106.3 8.0 0.046 0.0 FAD
HOH
 3.113
4.815
 HG21
O
 H62A
O
ILE C:33 C:12 8.0 0.046 E -102.0 105.6 NA NA NA
ILE D:33 D:12 9.0 0.051 E -102.6 104.8 NA NA NA
ILE E:33 E:12 9.0 0.051 E -102.5 106.6 NA NA NA
ILE F:33 F:12 10.0 0.057 E -100.7 107.3 NA NA NA
ILE G:33 G:12 9.0 0.051 E -102.3 106.2 NA NA NA
ILE H:33 H:12 9.0 0.051 E -102.4 106.1 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 8.0 0.046 E -101.8 105.5 8.0 0.046 0.0 FAD
SO4
HOH
 3.134
9.440
5.046
 HG23
HD13
O
 N1A
O3
O
ILE B:34 B:12 9.0 0.051 E -101.4 105.0 9.0 0.051 0.0 FAD
SO4
HOH
 3.153
9.451
4.903
 HG23
HD13
O
 N1A
O1
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ILE A:34 A:12 8.0 0.046 E -101.8 111.3 8.0 0.046 0.0 FAD
GOL
HOH
 3.637
9.357
5.049
 CG2
CD1
O
 N1A
O1
O
ILE B:34 B:12 9.0 0.051 E -105.3 105.5 9.0 0.051 0.0 FAD
HOH
 3.566
5.012
 CG2
O
 N1A
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ILE A:34 A:12 9.0 0.051 E -104.5 106.1 9.0 0.051 0.0 FAD
SO4
HOH
 3.537
9.731
5.108
 CG2
CD1
O
 N1A
O4
O
ILE B:34 B:12 8.0 0.046 E -107.5 105.6 8.0 0.046 0.0 FAD
SO4
HOH
 3.638
9.945
5.031
 CG2
CD1
O
 N1A
O1
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 8.0 0.046 E -100.8 106.5 8.0 0.046 0.0 FAD
SO4
BTB
HOH
 3.217
9.326
8.322
5.040
 HG23
HD13
HG22
O
 N1A
O3
HO6
O
ILE B:34 B:12 9.0 0.051 E -101.0 106.2 9.0 0.051 0.0 FAD
SO4
BTB
HOH
 3.147
9.403
8.433
4.995
 HG21
HD12
HG22
O
 H62A
O2
HO8
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 8.0 0.046 E -100.3 105.9 8.0 0.046 0.0 FAD
SO4
BTB
HOH
 3.236
9.127
8.194
5.067
 HG23
HD12
HG22
O
 N1A
O3
HO8
O
ILE B:34 B:12 9.0 0.051 E -100.2 106.6 9.0 0.051 0.0 FAD
SO4
BTB
HOH
 3.228
9.377
8.399
5.005
 HG23
HG21
HG22
O
 N1A
O1
HO8
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 9.0 0.051 E -103.1 105.6 9.0 0.051 0.0 FAD
SO4
HOH
 3.227
9.306
5.102
 HG23
HD12
HG21
 N1A
O3
O
ILE B:34 B:12 8.0 0.046 E -102.9 105.6 8.0 0.046 0.0 FAD
SO4
HOH
 3.090
9.506
4.992
 HG21
HG21
HG21
 H62A
O2
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:34 A:12 7.0 0.04 E -106.3 105.1 7.0 0.04 0.0 FAD
SO4
HOH
 3.339
9.287
5.243
 HG23
HD12
HG21
 N1A
O4
O
ILE B:34 B:12 9.0 0.051 E -103.8 106.1 9.0 0.051 0.0 FAD
 3.222
 HG22
 C2A
ILE C:34 C:12 8.0 0.046 E -105.0 106.9 NA NA NA
ILE D:34 D:12 8.0 0.046 E -103.2 105.7 NA NA NA
ILE E:34 E:12 9.0 0.051 E -105.6 105.3 NA NA NA
ILE F:34 F:12 8.0 0.046 E -103.6 104.7 NA NA NA
ILE G:34 G:12 9.0 0.051 E -103.5 102.3 NA NA NA
ILE H:34 H:12 8.0 0.046 E -103.7 106.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ILE A:47 A:47 7.0 0.04 E -107.6 108.1