Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107542239 . A C CCDS5749.1:NM_000108.3:c.175Aaa>Caa_NP_000099.2:p.59K>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 LYS A:45 A:24 54.0 0.27 H -63.7 -40.2 7.0 0.035 0.235 B:P09622:0.235
 HOH
 3.101
 NZ
 O
LYS B:45 B:24 46.0 0.23 H -64.4 -46.2 10.0 0.05 0.18 A:P09622:0.18
LYS C:45 C:24 49.0 0.245 H -60.7 -47.4 NA NA NA
LYS D:45 D:24 59.0 0.295 H -73.0 -42.7 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 LYS A:24 A:24 39.0 0.195 H -68.6 -34.1 1.0 0.005 0.19 B:P09622:0.19
LYS B:24 B:24 43.0 0.215 H -51.4 -55.7 3.0 0.015 0.2 A:P09622:0.2
 HOH
 6.283
 O
 O
LYS C:24 C:24 57.0 0.285 H -52.3 -49.4 NA NA NA
LYS D:24 D:24 54.0 0.27 H -85.5 -36.3 NA NA NA
LYS E:24 E:24 59.0 0.295 H -74.4 -41.2 NA NA NA
LYS F:24 F:24 51.0 0.255 H -54.0 -49.0 NA NA NA
LYS G:24 G:24 62.0 0.31 H -65.4 -33.5 NA NA NA
LYS H:24 H:24 54.0 0.27 H -52.9 -49.3 NA NA NA
LYS I:24 I:24 56.0 0.28 H -74.7 -15.7 NA NA NA
LYS J:24 J:24 56.0 0.28 H -55.6 -25.1 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 59.0 0.295 H -62.9 -42.6 4.0 0.02 0.275 B:P09622:0.275
 HOH
 2.069
 HZ2
 O
LYS B:46 B:24 65.0 0.325 H -63.7 -41.0 7.0 0.035 0.29 A:P09622:0.29
 HOH
 2.011
 HZ2
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 70.0 0.35 H -61.9 -43.6 23.0 0.115 0.235 B:P09622:0.235
 1PE
HOH
 1.720
2.566
 HZ3
HZ1
 OH4
O
LYS B:46 B:24 65.0 0.325 H -62.9 -41.3 6.0 0.03 0.295 A:P09622:0.295
 HOH
 2.159
 HZ2
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:24 A:24 59.0 0.295 H -61.5 -46.7 3.0 0.015 0.28 B:P09622:0.28
 HOH
 3.171
 NZ
 O
LYS B:24 B:24 53.0 0.265 H -62.6 -31.0 2.0 0.01 0.255 A:P09622:0.255
 HOH
 2.793
 NZ
 O
LYS C:24 C:24 47.0 0.235 H -62.0 -25.9 NA NA NA
LYS D:24 D:24 57.0 0.285 H -59.2 -46.4 NA NA NA
LYS E:24 E:24 56.0 0.28 H -64.2 -40.7 NA NA NA
LYS F:24 F:24 59.0 0.295 H -58.8 -46.1 NA NA NA
LYS G:24 G:24 60.0 0.3 H -58.9 -44.5 NA NA NA
LYS H:24 H:24 59.0 0.295 H -62.9 -46.6 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:24 A:24 57.0 0.285 H -56.6 -45.9 2.0 0.01 0.275 B:P09622:0.275
 HOH
 3.003
 NZ
 O
LYS B:24 B:24 58.0 0.29 H -61.6 -34.8 2.0 0.01 0.28 A:P09622:0.28
 HOH
 2.601
 NZ
 O
LYS C:24 C:24 57.0 0.285 H -61.2 -37.1 NA NA NA
LYS D:24 D:24 58.0 0.29 H -59.6 -44.6 NA NA NA
LYS E:24 E:24 57.0 0.285 H -61.5 -41.1 NA NA NA
LYS F:24 F:24 55.0 0.275 H -56.9 -44.2 NA NA NA
LYS G:24 G:24 56.0 0.28 H -58.5 -44.1 NA NA NA
LYS H:24 H:24 56.0 0.28 H -61.2 -39.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 LYS A:24 A:24 53.0 0.265 H -62.2 -38.4 5.0 0.025 0.24 B:P09622:0.24
 HOH
 6.686
 O
 O
LYS B:24 B:24 53.0 0.265 H -70.4 -30.7 4.0 0.02 0.245 A:P09622:0.245
 HOH
 3.174
 CE
 O
LYS C:24 C:24 57.0 0.285 H -65.0 -41.1 NA NA NA
LYS D:24 D:24 56.0 0.28 H -59.9 -46.8 NA NA NA
LYS E:24 E:24 58.0 0.29 H -62.0 -40.0 NA NA NA
LYS F:24 F:24 52.0 0.26 H -63.8 -42.8 NA NA NA
LYS G:24 G:24 54.0 0.27 H -65.3 -41.4 NA NA NA
LYS H:24 H:24 59.0 0.295 H -65.2 -41.3 NA NA NA
LYS I:24 I:24 56.0 0.28 H -61.1 -38.9 NA NA NA
LYS J:24 J:24 57.0 0.285 H -67.9 -39.3 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 LYS A:45 A:24 40.0 0.2 H -64.2 -43.6 6.0 0.03 0.17 B:P09622:0.17
LYS B:45 B:24 59.0 0.295 H -66.1 -42.1 4.0 0.02 0.275 A:P09622:0.275
 HOH
 9.191
 HE3
 O
LYS C:45 C:24 63.0 0.315 H -64.8 -42.3 NA NA NA
LYS D:45 D:24 64.0 0.32 H -65.1 -39.1 NA NA NA
LYS E:45 E:24 52.0 0.26 H -64.2 -40.9 NA NA NA
LYS F:45 F:24 51.0 0.255 H -64.4 -42.4 NA NA NA
LYS G:45 G:24 64.0 0.32 H -62.5 -42.5 NA NA NA
LYS H:45 H:24 57.0 0.285 H -63.9 -41.4 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 66.0 0.33 H -62.3 -41.9 22.0 0.11 0.22 B:P09622:0.22
 1PE
HOH
 2.049
2.667
 HZ2
HZ3
 OH5
O
LYS B:46 B:24 62.0 0.31 H -61.7 -39.9 4.0 0.02 0.29 A:P09622:0.29
 HOH
 2.205
 HZ2
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 LYS A:46 A:24 53.0 0.265 H -65.5 -44.5 2.0 0.01 0.255 B:P09622:0.255
 HOH
 2.932
 NZ
 O
LYS B:46 B:24 61.0 0.305 H -65.4 -41.4 2.0 0.01 0.295 A:P09622:0.295
 HOH
 2.570
 NZ
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 LYS A:46 A:24 57.0 0.285 H -67.7 -39.3 2.0 0.01 0.275 B:P09622:0.275
 HOH
 2.771
 NZ
 O
LYS B:46 B:24 57.0 0.285 H -66.1 -42.8 2.0 0.01 0.275 A:P09622:0.275
 HOH
 2.760
 NZ
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 60.0 0.3 H -65.8 -40.5 3.0 0.015 0.285 B:P09622:0.285
 HOH
 2.053
 HZ2
 O
LYS B:46 B:24 61.0 0.305 H -64.8 -40.5 2.0 0.01 0.295 A:P09622:0.295
 HOH
 1.975
 HZ2
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 62.0 0.31 H -65.7 -40.4 4.0 0.02 0.29 B:P09622:0.29
 HOH
 2.190
 HZ2
 O
LYS B:46 B:24 65.0 0.325 H -65.2 -38.2 7.0 0.035 0.29 A:P09622:0.29
 HOH
 2.176
 HZ1
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 59.0 0.295 H -64.5 -40.0 2.0 0.01 0.285 B:P09622:0.285
 HOH
 1.954
 HZ2
 O
LYS B:46 B:24 63.0 0.315 H -64.9 -40.4 2.0 0.01 0.305 A:P09622:0.305
 HOH
 1.911
 HZ3
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:46 A:24 61.0 0.305 H -65.3 -39.3 2.0 0.01 0.295 B:P09622:0.295
 HOH
 2.087
 HZ2
 O
LYS B:46 B:24 52.0 0.26 H -64.3 -37.6 3.0 0.015 0.245 A:P09622:0.245
 HOH
 2.663
 HE3
 O
LYS C:46 C:24 57.0 0.285 H -64.9 -39.5 NA NA NA
LYS D:46 D:24 64.0 0.32 H -65.4 -38.5 NA NA NA
LYS E:46 E:24 53.0 0.265 H -63.0 -39.3 NA NA NA
LYS F:46 F:24 55.0 0.275 H -64.6 -38.9 NA NA NA
LYS G:46 G:24 38.0 0.19 H -66.8 -37.2 NA NA NA
LYS H:46 H:24 53.0 0.265 H -64.9 -39.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:59 A:59 50.0 0.25 H -64.5 -41.4