Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107542249 | . | A | C | CCDS5749.1:NM_000108.3:c.185cAg>cCg_NP_000099.2:p.62Q>P | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLN | A:48 | A:27 | 112.0 | 0.622 | H | -67.4 | -20.9 | 16.0 | 0.089 | 0.533 |
B:P09622:0.533 |
HOH |
2.860 |
OE1 |
O |
|
GLN | B:48 | B:27 | 116.0 | 0.644 | H | -53.5 | -30.9 | 25.0 | 0.139 | 0.505 |
A:P09622:0.506 |
HOH |
9.241 |
NE2 |
O |
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GLN | C:48 | C:27 | 121.0 | 0.672 | H | -55.8 | -28.6 | NA | NA | NA | |||||||||||||
GLN | D:48 | D:27 | 112.0 | 0.622 | H | -68.0 | -20.3 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLN | A:27 | A:27 | 118.0 | 0.656 | H | -50.7 | -24.8 | 30.0 | 0.167 | 0.489 |
B:P09622:0.489 |
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GLN | B:27 | B:27 | 114.0 | 0.633 | H | -74.1 | -11.8 | 30.0 | 0.167 | 0.466 |
A:P09622:0.467 |
HOH |
3.193 |
CA |
O |
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GLN | C:27 | C:27 | 115.0 | 0.639 | H | -55.6 | -21.5 | NA | NA | NA | |||||||||||||
GLN | D:27 | D:27 | 115.0 | 0.639 | H | -66.2 | -27.1 | NA | NA | NA | |||||||||||||
GLN | E:27 | E:27 | 115.0 | 0.639 | H | -72.1 | -13.2 | NA | NA | NA | |||||||||||||
GLN | F:27 | F:27 | 107.0 | 0.594 | H | -72.6 | -10.1 | NA | NA | NA | |||||||||||||
GLN | G:27 | G:27 | 114.0 | 0.633 | H | -75.9 | -13.3 | NA | NA | NA | |||||||||||||
GLN | H:27 | H:27 | 112.0 | 0.622 | H | -47.9 | -20.2 | NA | NA | NA | |||||||||||||
GLN | I:27 | I:27 | 117.0 | 0.65 | T | -58.3 | -30.2 | NA | NA | NA | |||||||||||||
GLN | J:27 | J:27 | 115.0 | 0.639 | T | -66.4 | -9.7 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 115.0 | 0.639 | H | -64.5 | -29.3 | 30.0 | 0.167 | 0.472 |
B:P09622:0.472 |
HOH |
2.696 |
OE1 |
O |
|
GLN | B:49 | B:27 | 114.0 | 0.633 | H | -64.8 | -27.5 | 24.0 | 0.133 | 0.5 |
A:P09622:0.5 |
HOH |
2.727 |
OE1 |
O |
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6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 111.0 | 0.617 | H | -64.5 | -28.5 | 37.0 | 0.206 | 0.411 |
B:P09622:0.411 |
1PE HOH |
2.961 2.789 |
HB3 O |
H121 O |
|
GLN | B:49 | B:27 | 108.0 | 0.6 | H | -64.2 | -27.1 | 23.0 | 0.128 | 0.472 |
A:P09622:0.472 |
HOH |
2.630 |
OE1 |
O |
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1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLN | A:27 | A:27 | 109.0 | 0.606 | H | -67.8 | -19.3 | 22.0 | 0.122 | 0.484 |
B:P09622:0.483 |
HOH |
2.799 |
O |
O |
|
GLN | B:27 | B:27 | 112.0 | 0.622 | T | -63.1 | -11.3 | 24.0 | 0.133 | 0.489 |
A:P09622:0.489 |
HOH |
2.992 |
OE1 |
O |
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GLN | C:27 | C:27 | 112.0 | 0.622 | T | -70.0 | -16.1 | NA | NA | NA | |||||||||||||
GLN | D:27 | D:27 | 110.0 | 0.611 | H | -66.1 | -26.7 | NA | NA | NA | |||||||||||||
GLN | E:27 | E:27 | 110.0 | 0.611 | H | -71.7 | -14.7 | NA | NA | NA | |||||||||||||
GLN | F:27 | F:27 | 111.0 | 0.617 | H | -63.8 | -26.8 | NA | NA | NA | |||||||||||||
GLN | G:27 | G:27 | 111.0 | 0.617 | H | -73.4 | -22.7 | NA | NA | NA | |||||||||||||
GLN | H:27 | H:27 | 115.0 | 0.639 | H | -59.8 | -17.6 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLN | A:27 | A:27 | 116.0 | 0.644 | H | -63.8 | -26.7 | 22.0 | 0.122 | 0.522 |
B:P09622:0.522 |
HOH |
2.674 |
O |
O |
|
GLN | B:27 | B:27 | 112.0 | 0.622 | H | -66.0 | -18.5 | 26.0 | 0.144 | 0.478 |
A:P09622:0.478 |
HOH |
2.627 |
OE1 |
O |
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GLN | C:27 | C:27 | 111.0 | 0.617 | H | -61.9 | -19.4 | NA | NA | NA | |||||||||||||
GLN | D:27 | D:27 | 115.0 | 0.639 | H | -61.4 | -31.5 | NA | NA | NA | |||||||||||||
GLN | E:27 | E:27 | 117.0 | 0.65 | H | -63.0 | -25.7 | NA | NA | NA | |||||||||||||
GLN | F:27 | F:27 | 111.0 | 0.617 | H | -62.8 | -32.2 | NA | NA | NA | |||||||||||||
GLN | G:27 | G:27 | 111.0 | 0.617 | H | -65.3 | -24.7 | NA | NA | NA | |||||||||||||
GLN | H:27 | H:27 | 113.0 | 0.628 | H | -60.2 | -24.9 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLN | A:27 | A:27 | 110.0 | 0.611 | H | -63.2 | -13.3 | 26.0 | 0.144 | 0.467 |
B:P09622:0.467 |
HOH |
2.681 |
O |
O |
|
GLN | B:27 | B:27 | 103.0 | 0.572 | T | -74.3 | -5.4 | 23.0 | 0.128 | 0.444 |
A:P09622:0.444 |
HOH |
2.729 |
OE1 |
O |
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GLN | C:27 | C:27 | 111.0 | 0.617 | H | -64.0 | -25.7 | NA | NA | NA | |||||||||||||
GLN | D:27 | D:27 | 115.0 | 0.639 | H | -67.3 | -25.8 | NA | NA | NA | |||||||||||||
GLN | E:27 | E:27 | 110.0 | 0.611 | H | -65.4 | -32.6 | NA | NA | NA | |||||||||||||
GLN | F:27 | F:27 | 115.0 | 0.639 | H | -69.3 | -18.5 | NA | NA | NA | |||||||||||||
GLN | G:27 | G:27 | 112.0 | 0.622 | H | -58.5 | -23.0 | NA | NA | NA | |||||||||||||
GLN | H:27 | H:27 | 111.0 | 0.617 | H | -70.0 | -22.4 | NA | NA | NA | |||||||||||||
GLN | I:27 | I:27 | 114.0 | 0.633 | H | -64.5 | -19.3 | NA | NA | NA | |||||||||||||
GLN | J:27 | J:27 | 113.0 | 0.628 | H | -62.8 | -20.5 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLN | A:48 | A:27 | 115.0 | 0.639 | H | -65.2 | -22.3 | 31.0 | 0.172 | 0.467 |
B:P09622:0.467 |
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GLN | B:48 | B:27 | 109.0 | 0.606 | H | -65.5 | -22.6 | 30.0 | 0.167 | 0.439 |
A:P09622:0.439 |
HOH |
9.614 |
O |
O |
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GLN | C:48 | C:27 | 109.0 | 0.606 | H | -64.8 | -22.5 | NA | NA | NA | |||||||||||||
GLN | D:48 | D:27 | 108.0 | 0.6 | H | -65.2 | -21.7 | NA | NA | NA | |||||||||||||
GLN | E:48 | E:27 | 113.0 | 0.628 | H | -65.0 | -21.1 | NA | NA | NA | |||||||||||||
GLN | F:48 | F:27 | 115.0 | 0.639 | H | -64.6 | -22.1 | NA | NA | NA | |||||||||||||
GLN | G:48 | G:27 | 107.0 | 0.594 | H | -66.6 | -23.3 | NA | NA | NA | |||||||||||||
GLN | H:48 | H:27 | 111.0 | 0.617 | H | -65.2 | -23.4 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 115.0 | 0.639 | H | -63.5 | -29.1 | 39.0 | 0.217 | 0.422 |
B:P09622:0.422 |
1PE HOH |
2.531 2.703 |
HB3 OE1 |
H161 O |
|
GLN | B:49 | B:27 | 112.0 | 0.622 | H | -64.3 | -27.4 | 21.0 | 0.117 | 0.505 |
A:P09622:0.506 |
HOH |
2.713 |
OE1 |
O |
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5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLN | A:49 | A:27 | 111.0 | 0.617 | H | -67.8 | -23.9 | 23.0 | 0.128 | 0.489 |
B:P09622:0.489 |
HOH |
2.693 |
OE1 |
O |
|
GLN | B:49 | B:27 | 109.0 | 0.606 | H | -65.7 | -29.1 | 23.0 | 0.128 | 0.478 |
A:P09622:0.478 |
HOH |
2.771 |
OE1 |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLN | A:49 | A:27 | 110.0 | 0.611 | H | -65.0 | -28.1 | 21.0 | 0.117 | 0.494 |
B:P09622:0.494 |
HOH |
2.678 |
OE1 |
O |
|
GLN | B:49 | B:27 | 114.0 | 0.633 | H | -61.5 | -31.2 | 23.0 | 0.128 | 0.505 |
A:P09622:0.506 |
HOH |
2.766 |
OE1 |
O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 111.0 | 0.617 | H | -67.5 | -25.2 | 23.0 | 0.128 | 0.489 |
B:P09622:0.489 |
HOH |
2.694 |
O |
O |
|
GLN | B:49 | B:27 | 113.0 | 0.628 | H | -67.4 | -24.7 | 21.0 | 0.117 | 0.511 |
A:P09622:0.511 |
HOH |
2.666 |
HG2 |
O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 113.0 | 0.628 | H | -62.9 | -29.0 | 26.0 | 0.144 | 0.484 |
B:P09622:0.483 |
HOH |
2.713 |
OE1 |
O |
|
GLN | B:49 | B:27 | 113.0 | 0.628 | H | -63.1 | -27.9 | 23.0 | 0.128 | 0.5 |
A:P09622:0.5 |
HOH |
2.628 |
O |
O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 111.0 | 0.617 | H | -61.7 | -27.9 | 21.0 | 0.117 | 0.5 |
B:P09622:0.5 |
HOH |
2.597 |
OE1 |
O |
|
GLN | B:49 | B:27 | 112.0 | 0.622 | H | -61.8 | -27.4 | 23.0 | 0.128 | 0.494 |
A:P09622:0.494 |
HOH |
2.722 |
HG2 |
O |
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6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:49 | A:27 | 114.0 | 0.633 | H | -65.7 | -26.8 | 24.0 | 0.133 | 0.5 |
B:P09622:0.5 |
HOH |
2.721 |
HE21 |
O |
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GLN | B:49 | B:27 | 116.0 | 0.644 | H | -65.0 | -25.7 | 16.0 | 0.089 | 0.555 |
A:P09622:0.556 |
HOH |
1.928 |
HE22 |
O |
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GLN | C:49 | C:27 | 114.0 | 0.633 | H | -65.5 | -27.1 | NA | NA | NA | |||||||||||||
GLN | D:49 | D:27 | 114.0 | 0.633 | H | -67.1 | -25.2 | NA | NA | NA | |||||||||||||
GLN | E:49 | E:27 | 117.0 | 0.65 | H | -67.7 | -28.4 | NA | NA | NA | |||||||||||||
GLN | F:49 | F:27 | 117.0 | 0.65 | H | -66.9 | -26.5 | NA | NA | NA | |||||||||||||
GLN | G:49 | G:27 | 121.0 | 0.672 | H | -68.9 | -30.5 | NA | NA | NA | |||||||||||||
GLN | H:49 | H:27 | 112.0 | 0.622 | H | -67.6 | -26.9 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLN | A:62 | A:62 | 117.0 | 0.65 | H | -64.3 | -30.6 |