Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107542785 . A C CCDS5749.1:NM_000108.3:c.214Aaa>Caa_NP_000099.2:p.72K>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 LYS A:58 A:37 91.0 0.455 -81.5 -28.0 91.0 0.455 0.0 FAD
HOH
 2.875
2.939
 NZ
NZ
 O2B
O
LYS B:58 B:37 88.0 0.44 S -55.4 -35.1 88.0 0.44 0.0 FAD
 2.752
 NZ
 O2B
LYS C:58 C:37 94.0 0.47 -91.4 -25.3 NA NA NA
LYS D:58 D:37 81.0 0.405 -88.0 -17.5 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 LYS A:37 A:37 93.0 0.465 S -69.6 -33.0 93.0 0.465 0.0 FAD
HOH
 3.008
2.495
 N
NZ
 C2A
O
LYS B:37 B:37 88.0 0.44 -69.7 -37.9 88.0 0.44 0.0 FAD
HOH
 3.295
6.145
 CG
CE
 N3A
O
LYS C:37 C:37 81.0 0.405 S -72.6 -39.1 NA NA NA
LYS D:37 D:37 86.0 0.43 -78.2 -19.1 NA NA NA
LYS E:37 E:37 89.0 0.445 -69.9 -22.6 NA NA NA
LYS F:37 F:37 82.0 0.41 -72.0 -27.2 NA NA NA
LYS G:37 G:37 100.0 0.5 S -40.8 -49.9 NA NA NA
LYS H:37 H:37 85.0 0.425 -73.7 -41.4 NA NA NA
LYS I:37 I:37 107.0 0.535 S -60.7 -50.5 NA NA NA
LYS J:37 J:37 83.0 0.415 -84.8 -31.5 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 94.0 0.47 -83.8 -27.1 94.0 0.47 0.0 FAD
BTB
HOH
 2.310
2.103
2.558
 HZ3
HZ2
O
 O2B
O6
O
LYS B:59 B:37 92.0 0.46 -83.4 -25.1 92.0 0.46 0.0 FAD
BTB
HOH
 2.300
1.949
4.301
 HZ2
HZ1
HZ3
 O2B
O8
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 94.0 0.47 -86.3 -23.5 94.0 0.47 0.0 FAD
HOH
 2.381
2.205
 HZ1
HZ3
 O2B
O
LYS B:59 B:37 90.0 0.45 -86.5 -23.7 90.0 0.45 0.0 FAD
HOH
 2.153
2.078
 HZ2
HZ1
 HO2A
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:37 A:37 98.0 0.49 S -80.1 -31.3 98.0 0.49 0.0 FAD
HOH
 3.055
2.686
 NZ
O
 O2B
O
LYS B:37 B:37 90.0 0.45 -81.4 -25.3 90.0 0.45 0.0 FAD
HOH
 3.029
2.690
 CE
NZ
 O2B
O
LYS C:37 C:37 97.0 0.485 S -78.8 -18.9 NA NA NA
LYS D:37 D:37 93.0 0.465 S -76.7 -30.5 NA NA NA
LYS E:37 E:37 91.0 0.455 -67.3 -30.1 NA NA NA
LYS F:37 F:37 89.0 0.445 -80.6 -26.0 NA NA NA
LYS G:37 G:37 95.0 0.475 -83.0 -30.3 NA NA NA
LYS H:37 H:37 89.0 0.445 -75.7 -38.9 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:37 A:37 93.0 0.465 -86.8 -27.5 93.0 0.465 0.0 FAD
HOH
 2.946
3.021
 NZ
NZ
 O2B
O
LYS B:37 B:37 90.0 0.45 -70.5 -31.8 90.0 0.45 0.0 FAD
HOH
 2.967
2.961
 NZ
NZ
 O2B
O
LYS C:37 C:37 92.0 0.46 -73.2 -21.7 NA NA NA
LYS D:37 D:37 89.0 0.445 -84.6 -27.8 NA NA NA
LYS E:37 E:37 89.0 0.445 -75.2 -23.5 NA NA NA
LYS F:37 F:37 87.0 0.435 -79.4 -29.4 NA NA NA
LYS G:37 G:37 92.0 0.46 -83.1 -29.2 NA NA NA
LYS H:37 H:37 85.0 0.425 -83.0 -27.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 LYS A:37 A:37 89.0 0.445 S -82.2 -28.5 89.0 0.445 0.0 FAD
HOH
 3.211
3.118
 NZ
NZ
 O2B
O
LYS B:37 B:37 100.0 0.5 S -78.7 -36.5 100.0 0.5 0.0 FAD
HOH
 3.294
6.333
 NZ
N
 O2B
O
LYS C:37 C:37 89.0 0.445 S -80.7 -26.4 NA NA NA
LYS D:37 D:37 93.0 0.465 S -76.7 -30.7 NA NA NA
LYS E:37 E:37 97.0 0.485 S -83.4 -30.2 NA NA NA
LYS F:37 F:37 91.0 0.455 -84.6 -13.9 NA NA NA
LYS G:37 G:37 94.0 0.47 S -84.7 -32.2 NA NA NA
LYS H:37 H:37 91.0 0.455 S -82.5 -23.5 NA NA NA
LYS I:37 I:37 92.0 0.46 S -73.1 -28.9 NA NA NA
LYS J:37 J:37 94.0 0.47 -79.9 -25.3 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 LYS A:58 A:37 88.0 0.44 -78.0 -34.1 88.0 0.44 0.0 FAD
TRS
HOH
 2.520
2.226
4.684
 HZ2
HZ1
HE3
 O2B
O3
O
LYS B:58 B:37 83.0 0.415 -76.3 -32.1 83.0 0.415 0.0 FAD
HOH
 2.456
4.893
 HZ2
HE3
 HO2A
O
LYS C:58 C:37 88.0 0.44 S -75.4 -33.1 NA NA NA
LYS D:58 D:37 88.0 0.44 -73.2 -32.3 NA NA NA
LYS E:58 E:37 88.0 0.44 S -74.7 -34.8 NA NA NA
LYS F:58 F:37 91.0 0.455 -78.3 -33.4 NA NA NA
LYS G:58 G:37 86.0 0.43 S -75.8 -35.1 NA NA NA
LYS H:58 H:37 94.0 0.47 -76.3 -34.3 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 93.0 0.465 -81.9 -26.5 93.0 0.465 0.0 FAD
HOH
 1.952
2.193
 HZ3
HZ2
 HO2A
O
LYS B:59 B:37 92.0 0.46 -82.2 -25.2 92.0 0.46 0.0 FAD
HOH
 2.015
2.169
 HZ2
HZ1
 HO2A
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 LYS A:59 A:37 93.0 0.465 -86.5 -27.2 93.0 0.465 0.0 FAD
HOH
 3.019
2.743
 NZ
O
 O2B
O
LYS B:59 B:37 91.0 0.455 -77.1 -34.7 91.0 0.455 0.0 FAD
HOH
 3.062
3.088
 NZ
NZ
 O2B
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 LYS A:59 A:37 92.0 0.46 -78.0 -31.7 92.0 0.46 0.0 FAD
HOH
 3.059
2.835
 NZ
O
 O2B
O
LYS B:59 B:37 91.0 0.455 -79.1 -29.1 91.0 0.455 0.0 FAD
HOH
 2.997
3.107
 NZ
NZ
 O2B
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 94.0 0.47 -84.0 -27.1 94.0 0.47 0.0 FAD
BTB
HOH
 2.246
2.029
2.060
 HZ2
HZ1
HZ3
 HO2A
O6
O
LYS B:59 B:37 94.0 0.47 -83.2 -27.4 94.0 0.47 0.0 FAD
BTB
HOH
 2.146
2.191
1.992
 HZ2
HZ1
HZ3
 HO2A
O8
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 95.0 0.475 -84.0 -26.7 95.0 0.475 0.0 FAD
BTB
HOH
 1.995
2.068
2.095
 HZ1
HZ2
HZ3
 HO2A
H71
O
LYS B:59 B:37 94.0 0.47 -84.1 -25.3 94.0 0.47 0.0 FAD
BTB
HOH
 2.158
2.034
3.391
 HZ2
HZ1
HB2
 HO2A
O8
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 92.0 0.46 -84.6 -29.4 92.0 0.46 0.0 FAD
HOH
 2.380
2.081
 HZ1
HZ3
 O2B
O
LYS B:59 B:37 93.0 0.465 -84.5 -30.6 93.0 0.465 0.0 FAD
SO4
HOH
 2.551
5.870
1.951
 HZ1
HZ3
HZ3
 O2B
O1
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:59 A:37 97.0 0.485 -81.1 -26.7 97.0 0.485 0.0 FAD
HOH
 2.212
2.311
 HE3
HZ1
 HO2A
O
LYS B:59 B:37 91.0 0.455 -84.4 -28.5 91.0 0.455 0.0 FAD
HOH
 2.670
7.401
 HD3
O
 C5A
O
LYS C:59 C:37 89.0 0.445 S -78.7 -27.1 NA NA NA
LYS D:59 D:37 96.0 0.48 S -80.7 -29.5 NA NA NA
LYS E:59 E:37 89.0 0.445 S -78.4 -29.5 NA NA NA
LYS F:59 F:37 96.0 0.48 S -78.5 -26.3 NA NA NA
LYS G:59 G:37 88.0 0.44 -79.3 -26.8 NA NA NA
LYS H:59 H:37 90.0 0.45 S -78.1 -24.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:72 A:72 96.0 0.48 -89.2 -21.2