Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107543980 . A C CCDS5749.1:NM_000108.3:c.325Aga>Cga_NP_000099.2:p.109R>R Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ARG A:95 A:74 102.0 0.453 T -98.0 -4.5 4.0 0.018 0.435 B:P09622:0.436
 HOH
 3.025
 NH1
 O
ARG B:95 B:74 97.0 0.431 T -92.9 -1.0 3.0 0.013 0.418 A:P09622:0.418
 HOH
 3.001
 NH1
 O
ARG C:95 C:74 92.0 0.409 T -93.4 1.9 NA NA NA
ARG D:95 D:74 102.0 0.453 G -110.3 7.9 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ARG A:74 A:74 105.0 0.467 T -121.3 28.7 4.0 0.018 0.449 B:P09622:0.449
 HOH
 3.149
 NH2
 O
ARG B:74 B:74 108.0 0.48 T -93.7 1.1 2.0 0.009 0.471 A:P09622:0.471
 HOH
 3.578
 NH1
 O
ARG C:74 C:74 100.0 0.444 T -104.6 -12.2 NA NA NA
ARG D:74 D:74 101.0 0.449 G -99.0 9.8 NA NA NA
ARG E:74 E:74 100.0 0.444 H -109.2 1.8 NA NA NA
ARG F:74 F:74 104.0 0.462 G -101.0 14.6 NA NA NA
ARG G:74 G:74 107.0 0.476 H -82.0 -15.0 NA NA NA
ARG H:74 H:74 104.0 0.462 G -99.7 8.6 NA NA NA
ARG I:74 I:74 111.0 0.493 G -95.7 -8.9 NA NA NA
ARG J:74 J:74 101.0 0.449 G -116.6 10.4 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 103.0 0.458 T -101.4 6.9 5.0 0.022 0.436 B:P09622:0.436
 SO4
HOH
 8.804
2.695
 HH21
HH12
 O4
O
ARG B:96 B:74 103.0 0.458 T -101.9 7.2 4.0 0.018 0.44 A:P09622:0.44
 SO4
HOH
 8.724
2.526
 HH21
HH12
 O1
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 107.0 0.476 T -102.1 7.8 6.0 0.027 0.449 B:P09622:0.449
 SO4
HOH
 8.696
2.681
 HH21
HH12
 O3
O
ARG B:96 B:74 106.0 0.471 T -103.1 8.3 4.0 0.018 0.453 A:P09622:0.453
 SO4
HOH
 8.911
2.426
 HH21
HH12
 O1
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:74 A:74 109.0 0.484 G -109.6 -1.4 5.0 0.022 0.462 B:P09622:0.462
 SO4
HOH
 9.538
2.589
 NH2
NH1
 O3
O
ARG B:74 B:74 99.0 0.44 G -99.7 1.4 6.0 0.027 0.413 A:P09622:0.413
 SO4
HOH
 9.609
2.854
 NH2
NH1
 O3
O
ARG C:74 C:74 98.0 0.436 G -102.9 7.2 NA NA NA
ARG D:74 D:74 113.0 0.502 G -107.4 0.8 NA NA NA
ARG E:74 E:74 106.0 0.471 G -106.2 3.2 NA NA NA
ARG F:74 F:74 115.0 0.511 G -103.9 1.1 NA NA NA
ARG G:74 G:74 107.0 0.476 T -110.3 9.3 NA NA NA
ARG H:74 H:74 100.0 0.444 T -98.8 -1.9 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:74 A:74 110.0 0.489 T -105.6 9.5 3.0 0.013 0.476 B:P09622:0.476
 SO4
HOH
 9.712
2.819
 NH2
NH1
 O3
O
ARG B:74 B:74 106.0 0.471 T -101.7 5.5 6.0 0.027 0.444 A:P09622:0.444
 SO4
HOH
 9.601
2.699
 NH2
NH1
 O3
O
ARG C:74 C:74 103.0 0.458 T -99.4 7.5 NA NA NA
ARG D:74 D:74 117.0 0.52 T -102.3 1.3 NA NA NA
ARG E:74 E:74 109.0 0.484 T -98.3 5.7 NA NA NA
ARG F:74 F:74 113.0 0.502 T -99.6 4.2 NA NA NA
ARG G:74 G:74 115.0 0.511 T -105.4 8.4 NA NA NA
ARG H:74 H:74 107.0 0.476 T -100.5 0.9 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ARG A:74 A:74 102.0 0.453 T -103.0 9.2 4.0 0.018 0.435 B:P09622:0.436
 SO4
HOH
 9.717
3.116
 NH2
NH1
 O1
O
ARG B:74 B:74 112.0 0.498 T -101.9 9.5 4.0 0.018 0.48 A:P09622:0.48
 SO4
HOH
 9.890
3.073
 NH2
NH1
 O4
O
ARG C:74 C:74 102.0 0.453 G -104.3 4.3 NA NA NA
ARG D:74 D:74 105.0 0.467 T -104.6 7.0 NA NA NA
ARG E:74 E:74 109.0 0.484 T -102.5 3.6 NA NA NA
ARG F:74 F:74 100.0 0.444 G -110.2 8.4 NA NA NA
ARG G:74 G:74 103.0 0.458 T -99.7 8.6 NA NA NA
ARG H:74 H:74 102.0 0.453 G -102.8 4.4 NA NA NA
ARG I:74 I:74 111.0 0.493 H -90.9 0.5 NA NA NA
ARG J:74 J:74 107.0 0.476 H -99.3 -6.8 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ARG A:95 A:74 111.0 0.493 T -99.3 6.3 6.0 0.027 0.466 B:P09622:0.467
 HOH
 2.905
 HH12
 O
ARG B:95 B:74 103.0 0.458 T -97.1 6.3 5.0 0.022 0.436 A:P09622:0.436
 HOH
 3.981
 HH21
 O
ARG C:95 C:74 109.0 0.484 T -98.8 6.1 NA NA NA
ARG D:95 D:74 111.0 0.493 T -95.6 6.5 NA NA NA
ARG E:95 E:74 115.0 0.511 T -98.1 7.6 NA NA NA
ARG F:95 F:74 101.0 0.449 T -98.5 8.3 NA NA NA
ARG G:95 G:74 108.0 0.48 T -95.2 7.1 NA NA NA
ARG H:95 H:74 103.0 0.458 T -100.0 8.0 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 92.0 0.409 T -100.0 7.8 4.0 0.018 0.391 B:P09622:0.391
 SO4
HOH
 8.714
6.351
 HH21
HH12
 O3
O
ARG B:96 B:74 90.0 0.4 T -99.5 8.0 1.0 0.004 0.396 A:P09622:0.396
 SO4
HOH
 8.976
2.648
 HH21
HH12
 O1
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ARG A:96 A:74 110.0 0.489 T -96.2 9.7 5.0 0.022 0.467 B:P09622:0.467
 HOH
 3.018
 NH1
 O
ARG B:96 B:74 107.0 0.476 T -100.2 8.5 6.0 0.027 0.449 A:P09622:0.449
 HOH
 2.957
 NH1
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ARG A:96 A:74 106.0 0.471 G -103.5 9.1 3.0 0.013 0.458 B:P09622:0.458
 SO4
HOH
 9.622
3.001
 NH2
NH1
 O3
O
ARG B:96 B:74 106.0 0.471 T -99.0 12.5 4.0 0.018 0.453 A:P09622:0.453
 SO4
SO4
HOH
 8.835
9.760
3.015
 NH2
NH2
NH1
 O4
O2
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 109.0 0.484 T -101.0 7.1 7.0 0.031 0.453 B:P09622:0.453
 SO4
HOH
 8.597
2.624
 HH21
HH12
 O3
O
ARG B:96 B:74 90.0 0.4 T -101.4 7.2 2.0 0.009 0.391 A:P09622:0.391
 SO4
HOH
 8.705
2.608
 HH21
HH12
 O1
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 105.0 0.467 T -100.5 7.8 5.0 0.022 0.445 B:P09622:0.444
 SO4
HOH
 8.835
2.573
 HH21
HH12
 O3
O
ARG B:96 B:74 90.0 0.4 T -102.2 7.3 1.0 0.004 0.396 A:P09622:0.396
 SO4
HOH
 8.700
2.610
 HH21
HH12
 O1
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 108.0 0.48 T -95.4 4.8 6.0 0.027 0.453 B:P09622:0.453
 SO4
HOH
 8.649
2.490
 HH21
HH12
 O3
O
ARG B:96 B:74 91.0 0.404 T -99.4 4.6 2.0 0.009 0.395 A:P09622:0.396
 SO4
HOH
 9.210
2.606
 HH21
HH12
 O2
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:96 A:74 114.0 0.507 T -100.1 11.6 7.0 0.031 0.476 B:P09622:0.476
 SO4
HOH
 9.236
3.463
 HH21
HH12
 O3
O
ARG B:96 B:74 112.0 0.498 T -100.7 9.2 6.0 0.027 0.471 A:P09622:0.471
 SO4
HOH
 9.080
2.834
 HH21
HH12
 O3
O
ARG C:96 C:74 112.0 0.498 G -102.4 10.6 NA NA NA
ARG D:96 D:74 113.0 0.502 T -100.3 10.4 NA NA NA
ARG E:96 E:74 113.0 0.502 G -101.8 12.8 NA NA NA
ARG F:96 F:74 116.0 0.516 T -103.5 17.5 NA NA NA
ARG G:96 G:74 112.0 0.498 T -100.4 12.3 NA NA NA
ARG H:96 H:74 110.0 0.489 G -106.0 8.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ARG A:109 A:109 101.0 0.449 T -103.9 6.4