Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107545408 . G A CCDS5749.1:NM_000108.3:c.343Gaa>Aaa_NP_000099.2:p.115E>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
2011-05-04 GLU A:101 A:80 154.0 0.811 -133.7 106.4 109.0 0.574 0.237 B:P09622:0.237
GLU B:101 B:80 132.0 0.695 -132.1 144.9 94.0 0.495 0.2 A:P09622:0.2
GLU C:101 C:80 118.0 0.621 -147.1 90.1 NA NA NA
GLU D:101 D:80 146.0 0.768 -142.8 140.1 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
2005-11-15 GLU A:80 A:80 128.0 0.674 -127.7 162.8 86.0 0.453 0.221 B:P09622:0.221
GLU B:80 B:80 129.0 0.679 -118.0 138.5 84.0 0.442 0.237 A:P09622:0.237
GLU C:80 C:80 128.0 0.674 -132.2 137.6 NA NA NA
GLU D:80 D:80 149.0 0.784 -142.1 139.0 NA NA NA
GLU E:80 E:80 144.0 0.758 -126.1 127.6 NA NA NA
GLU F:80 F:80 127.0 0.668 -140.7 135.7 NA NA NA
GLU G:80 G:80 145.0 0.763 -149.7 148.8 NA NA NA
GLU H:80 H:80 162.0 0.853 -146.0 152.6 NA NA NA
GLU I:80 I:80 127.0 0.668 -135.6 161.3 NA NA NA
GLU J:80 J:80 132.0 0.695 -142.5 115.9 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
2019-11-20 GLU A:102 A:80 140.0 0.737 -144.1 107.4 116.0 0.611 0.126 B:P09622:0.126
HOH
5.547
OE2
O
GLU B:102 B:80 152.0 0.8 -139.9 105.9 124.0 0.653 0.147 A:P09622:0.147
HOH
2.397
OE2
O
6i4t 1 P09622 99.79 0.0 X-RAY
2019-11-20 GLU A:102 A:80 127.0 0.668 -138.2 110.3 77.0 0.405 0.263 B:P09622:0.263
HOH
7.609
O
O
GLU B:102 B:80 119.0 0.626 -141.3 114.3 75.0 0.395 0.231 A:P09622:0.232
HOH
7.524
O
O
1zmc 1 P09622 99.79 0.0 X-RAY
2005-06-28 GLU A:80 A:80 138.0 0.726 -111.9 130.1 111.0 0.584 0.142 B:P09622:0.142
HOH
6.765
N
O
GLU B:80 B:80 129.0 0.679 -127.1 141.0 106.0 0.558 0.121 A:P09622:0.121
HOH
4.295
O
O
GLU C:80 C:80 127.0 0.668 -135.9 148.0 NA NA NA
GLU D:80 D:80 137.0 0.721 63.4 85.8 NA NA NA
GLU E:80 E:80 129.0 0.679 -151.0 148.5 NA NA NA
GLU F:80 F:80 123.0 0.647 -152.2 128.5 NA NA NA
GLU G:80 G:80 130.0 0.684 -114.6 118.1 NA NA NA
GLU H:80 H:80 129.0 0.679 -135.8 152.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
2005-06-28 GLU A:80 A:80 152.0 0.8 -140.0 104.5 122.0 0.642 0.158 B:P09622:0.158
HOH
6.719
N
O
GLU B:80 B:80 125.0 0.658 -139.0 148.1 91.0 0.479 0.179 A:P09622:0.179
HOH
4.176
O
O
GLU C:80 C:80 141.0 0.742 -143.8 143.4 NA NA NA
GLU D:80 D:80 140.0 0.737 56.3 93.1 NA NA NA
GLU E:80 E:80 130.0 0.684 -141.0 138.9 NA NA NA
GLU F:80 F:80 124.0 0.653 -118.7 111.1 NA NA NA
GLU G:80 G:80 122.0 0.642 -113.0 128.7 NA NA NA
GLU H:80 H:80 138.0 0.726 -138.6 146.8 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
2006-01-17 GLU A:80 A:80 138.0 0.726 -148.5 126.5 115.0 0.605 0.121 B:P09622:0.121
HOH
7.531
O
O
GLU B:80 B:80 136.0 0.716 -141.1 148.0 101.0 0.532 0.184 A:P09622:0.184
HOH
7.326
N
O
GLU C:80 C:80 155.0 0.816 -146.3 137.8 NA NA NA
GLU D:80 D:80 114.0 0.6 -138.9 120.0 NA NA NA
GLU E:80 E:80 143.0 0.753 -142.5 138.6 NA NA NA
GLU F:80 F:80 121.0 0.637 -142.6 137.8 NA NA NA
GLU G:80 G:80 146.0 0.768 -146.2 145.3 NA NA NA
GLU H:80 H:80 120.0 0.632 -124.8 144.9 NA NA NA
GLU I:80 I:80 148.0 0.779 -127.2 163.6 NA NA NA
GLU J:80 J:80 127.0 0.668 -139.3 120.7 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
2018-05-16 GLU A:101 A:80 158.0 0.832 -146.2 134.0 124.0 0.653 0.179 B:P09622:0.179
HOH
9.922
O
O
GLU B:101 B:80 136.0 0.716 -148.2 141.0 101.0 0.532 0.184 A:P09622:0.184
HOH
9.002
C
O
GLU C:101 C:80 136.0 0.716 -148.1 142.2 NA NA NA
GLU D:101 D:80 115.0 0.605 -150.6 138.5 NA NA NA
GLU E:101 E:80 124.0 0.653 -150.4 139.7 NA NA NA
GLU F:101 F:80 137.0 0.721 -150.3 139.4 NA NA NA
GLU G:101 G:80 155.0 0.816 -151.9 141.2 NA NA NA
GLU H:101 H:80 145.0 0.763 -145.3 142.5 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
2019-11-20 GLU A:102 A:80 129.0 0.679 -141.1 117.9 86.0 0.453 0.226 B:P09622:0.226
HOH
6.096
HA
O
GLU B:102 B:80 142.0 0.747 -145.8 118.7 102.0 0.537 0.21 A:P09622:0.211
HOH
4.911
HA
O
5j5z 1 P09622 99.79 0.0 X-RAY
2017-11-15 GLU A:102 A:80 159.0 0.837 -143.3 146.5 123.0 0.647 0.19 B:P09622:0.189
HOH
7.628
O
O
GLU B:102 B:80 131.0 0.689 -143.4 137.8 93.0 0.489 0.2 A:P09622:0.2
HOH
7.690
N
O
6hg8 1 P09622 99.79 0.0 X-RAY
2019-09-04 GLU A:102 A:80 140.0 0.737 -152.8 75.6 103.0 0.542 0.195 B:P09622:0.195
HOH
2.612
OE1
O
GLU B:102 B:80 127.0 0.668 65.8 76.8 109.0 0.574 0.094 A:P09622:0.095
HOH
2.979
CG
O
6i4r 1 P09622 99.79 0.0 X-RAY
2019-11-20 GLU A:102 A:80 130.0 0.684 -136.7 138.3 81.0 0.426 0.258 B:P09622:0.258
HOH
7.319
N
O
GLU B:102 B:80 131.0 0.689 -139.4 140.8 83.0 0.437 0.252 A:P09622:0.253
HOH
7.385
O
O
6i4p 1 P09622 99.79 0.0 X-RAY
2019-11-20 GLU A:102 A:80 124.0 0.653 -147.4 113.0 88.0 0.463 0.19 B:P09622:0.189
HOH
7.735
H
O
GLU B:102 B:80 126.0 0.663 -147.7 114.6 91.0 0.479 0.184 A:P09622:0.184
HOH
7.425
O
O
6i4s 1 P09622 99.79 0.0 X-RAY
2019-11-20 GLU A:102 A:80 139.0 0.732 -143.2 122.6 96.0 0.505 0.227 B:P09622:0.226
HOH
7.595
O
O
GLU B:102 B:80 128.0 0.674 -148.0 123.0 89.0 0.468 0.206 A:P09622:0.205
HOH
7.511
O
O
6i4z 1 P09622 99.79 0.0 X-RAY
2019-11-20 GLU A:102 A:80 132.0 0.695 -147.9 125.3 82.0 0.432 0.263 B:P09622:0.263
GLU B:102 B:80 173.0 0.911 -154.6 136.8 151.0 0.795 0.116 A:P09622:0.116
GLU C:102 C:80 147.0 0.774 -146.2 129.7 NA NA NA
GLU D:102 D:80 139.0 0.732 -149.9 129.9 NA NA NA
GLU E:102 E:80 158.0 0.832 -148.7 131.1 NA NA NA
GLU F:102 F:80 139.0 0.732 -146.6 131.5 NA NA NA
GLU G:102 G:80 156.0 0.821 -145.1 130.3 NA NA NA
GLU H:102 H:80 161.0 0.847 -153.4 136.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 GLU A:115 A:115 131.0 0.689 -140.0 136.7