Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107545408 | . | G | A | CCDS5749.1:NM_000108.3:c.343Gaa>Aaa_NP_000099.2:p.115E>K | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLU | A:101 | A:80 | 154.0 | 0.811 | -133.7 | 106.4 | 109.0 | 0.574 | 0.237 |
B:P09622:0.237 |
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GLU | B:101 | B:80 | 132.0 | 0.695 | -132.1 | 144.9 | 94.0 | 0.495 | 0.2 |
A:P09622:0.2 |
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GLU | C:101 | C:80 | 118.0 | 0.621 | -147.1 | 90.1 | NA | NA | NA | ||||||||||||||
GLU | D:101 | D:80 | 146.0 | 0.768 | -142.8 | 140.1 | NA | NA | NA | ||||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLU | A:80 | A:80 | 128.0 | 0.674 | -127.7 | 162.8 | 86.0 | 0.453 | 0.221 |
B:P09622:0.221 |
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GLU | B:80 | B:80 | 129.0 | 0.679 | -118.0 | 138.5 | 84.0 | 0.442 | 0.237 |
A:P09622:0.237 |
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GLU | C:80 | C:80 | 128.0 | 0.674 | -132.2 | 137.6 | NA | NA | NA | ||||||||||||||
GLU | D:80 | D:80 | 149.0 | 0.784 | -142.1 | 139.0 | NA | NA | NA | ||||||||||||||
GLU | E:80 | E:80 | 144.0 | 0.758 | -126.1 | 127.6 | NA | NA | NA | ||||||||||||||
GLU | F:80 | F:80 | 127.0 | 0.668 | -140.7 | 135.7 | NA | NA | NA | ||||||||||||||
GLU | G:80 | G:80 | 145.0 | 0.763 | -149.7 | 148.8 | NA | NA | NA | ||||||||||||||
GLU | H:80 | H:80 | 162.0 | 0.853 | -146.0 | 152.6 | NA | NA | NA | ||||||||||||||
GLU | I:80 | I:80 | 127.0 | 0.668 | -135.6 | 161.3 | NA | NA | NA | ||||||||||||||
GLU | J:80 | J:80 | 132.0 | 0.695 | -142.5 | 115.9 | NA | NA | NA | ||||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 140.0 | 0.737 | -144.1 | 107.4 | 116.0 | 0.611 | 0.126 |
B:P09622:0.126 |
HOH |
5.547 |
OE2 |
O |
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GLU | B:102 | B:80 | 152.0 | 0.8 | -139.9 | 105.9 | 124.0 | 0.653 | 0.147 |
A:P09622:0.147 |
HOH |
2.397 |
OE2 |
O |
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6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 127.0 | 0.668 | -138.2 | 110.3 | 77.0 | 0.405 | 0.263 |
B:P09622:0.263 |
HOH |
7.609 |
O |
O |
||
GLU | B:102 | B:80 | 119.0 | 0.626 | -141.3 | 114.3 | 75.0 | 0.395 | 0.231 |
A:P09622:0.232 |
HOH |
7.524 |
O |
O |
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1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLU | A:80 | A:80 | 138.0 | 0.726 | -111.9 | 130.1 | 111.0 | 0.584 | 0.142 |
B:P09622:0.142 |
HOH |
6.765 |
N |
O |
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GLU | B:80 | B:80 | 129.0 | 0.679 | -127.1 | 141.0 | 106.0 | 0.558 | 0.121 |
A:P09622:0.121 |
HOH |
4.295 |
O |
O |
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GLU | C:80 | C:80 | 127.0 | 0.668 | -135.9 | 148.0 | NA | NA | NA | ||||||||||||||
GLU | D:80 | D:80 | 137.0 | 0.721 | 63.4 | 85.8 | NA | NA | NA | ||||||||||||||
GLU | E:80 | E:80 | 129.0 | 0.679 | -151.0 | 148.5 | NA | NA | NA | ||||||||||||||
GLU | F:80 | F:80 | 123.0 | 0.647 | -152.2 | 128.5 | NA | NA | NA | ||||||||||||||
GLU | G:80 | G:80 | 130.0 | 0.684 | -114.6 | 118.1 | NA | NA | NA | ||||||||||||||
GLU | H:80 | H:80 | 129.0 | 0.679 | -135.8 | 152.0 | NA | NA | NA | ||||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLU | A:80 | A:80 | 152.0 | 0.8 | -140.0 | 104.5 | 122.0 | 0.642 | 0.158 |
B:P09622:0.158 |
HOH |
6.719 |
N |
O |
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GLU | B:80 | B:80 | 125.0 | 0.658 | -139.0 | 148.1 | 91.0 | 0.479 | 0.179 |
A:P09622:0.179 |
HOH |
4.176 |
O |
O |
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GLU | C:80 | C:80 | 141.0 | 0.742 | -143.8 | 143.4 | NA | NA | NA | ||||||||||||||
GLU | D:80 | D:80 | 140.0 | 0.737 | 56.3 | 93.1 | NA | NA | NA | ||||||||||||||
GLU | E:80 | E:80 | 130.0 | 0.684 | -141.0 | 138.9 | NA | NA | NA | ||||||||||||||
GLU | F:80 | F:80 | 124.0 | 0.653 | -118.7 | 111.1 | NA | NA | NA | ||||||||||||||
GLU | G:80 | G:80 | 122.0 | 0.642 | -113.0 | 128.7 | NA | NA | NA | ||||||||||||||
GLU | H:80 | H:80 | 138.0 | 0.726 | -138.6 | 146.8 | NA | NA | NA | ||||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLU | A:80 | A:80 | 138.0 | 0.726 | -148.5 | 126.5 | 115.0 | 0.605 | 0.121 |
B:P09622:0.121 |
HOH |
7.531 |
O |
O |
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GLU | B:80 | B:80 | 136.0 | 0.716 | -141.1 | 148.0 | 101.0 | 0.532 | 0.184 |
A:P09622:0.184 |
HOH |
7.326 |
N |
O |
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GLU | C:80 | C:80 | 155.0 | 0.816 | -146.3 | 137.8 | NA | NA | NA | ||||||||||||||
GLU | D:80 | D:80 | 114.0 | 0.6 | -138.9 | 120.0 | NA | NA | NA | ||||||||||||||
GLU | E:80 | E:80 | 143.0 | 0.753 | -142.5 | 138.6 | NA | NA | NA | ||||||||||||||
GLU | F:80 | F:80 | 121.0 | 0.637 | -142.6 | 137.8 | NA | NA | NA | ||||||||||||||
GLU | G:80 | G:80 | 146.0 | 0.768 | -146.2 | 145.3 | NA | NA | NA | ||||||||||||||
GLU | H:80 | H:80 | 120.0 | 0.632 | -124.8 | 144.9 | NA | NA | NA | ||||||||||||||
GLU | I:80 | I:80 | 148.0 | 0.779 | -127.2 | 163.6 | NA | NA | NA | ||||||||||||||
GLU | J:80 | J:80 | 127.0 | 0.668 | -139.3 | 120.7 | NA | NA | NA | ||||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLU | A:101 | A:80 | 158.0 | 0.832 | -146.2 | 134.0 | 124.0 | 0.653 | 0.179 |
B:P09622:0.179 |
HOH |
9.922 |
O |
O |
||
GLU | B:101 | B:80 | 136.0 | 0.716 | -148.2 | 141.0 | 101.0 | 0.532 | 0.184 |
A:P09622:0.184 |
HOH |
9.002 |
C |
O |
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GLU | C:101 | C:80 | 136.0 | 0.716 | -148.1 | 142.2 | NA | NA | NA | ||||||||||||||
GLU | D:101 | D:80 | 115.0 | 0.605 | -150.6 | 138.5 | NA | NA | NA | ||||||||||||||
GLU | E:101 | E:80 | 124.0 | 0.653 | -150.4 | 139.7 | NA | NA | NA | ||||||||||||||
GLU | F:101 | F:80 | 137.0 | 0.721 | -150.3 | 139.4 | NA | NA | NA | ||||||||||||||
GLU | G:101 | G:80 | 155.0 | 0.816 | -151.9 | 141.2 | NA | NA | NA | ||||||||||||||
GLU | H:101 | H:80 | 145.0 | 0.763 | -145.3 | 142.5 | NA | NA | NA | ||||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 129.0 | 0.679 | -141.1 | 117.9 | 86.0 | 0.453 | 0.226 |
B:P09622:0.226 |
HOH |
6.096 |
HA |
O |
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GLU | B:102 | B:80 | 142.0 | 0.747 | -145.8 | 118.7 | 102.0 | 0.537 | 0.21 |
A:P09622:0.211 |
HOH |
4.911 |
HA |
O |
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5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLU | A:102 | A:80 | 159.0 | 0.837 | -143.3 | 146.5 | 123.0 | 0.647 | 0.19 |
B:P09622:0.189 |
HOH |
7.628 |
O |
O |
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GLU | B:102 | B:80 | 131.0 | 0.689 | -143.4 | 137.8 | 93.0 | 0.489 | 0.2 |
A:P09622:0.2 |
HOH |
7.690 |
N |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLU | A:102 | A:80 | 140.0 | 0.737 | -152.8 | 75.6 | 103.0 | 0.542 | 0.195 |
B:P09622:0.195 |
HOH |
2.612 |
OE1 |
O |
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GLU | B:102 | B:80 | 127.0 | 0.668 | 65.8 | 76.8 | 109.0 | 0.574 | 0.094 |
A:P09622:0.095 |
HOH |
2.979 |
CG |
O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 130.0 | 0.684 | -136.7 | 138.3 | 81.0 | 0.426 | 0.258 |
B:P09622:0.258 |
HOH |
7.319 |
N |
O |
||
GLU | B:102 | B:80 | 131.0 | 0.689 | -139.4 | 140.8 | 83.0 | 0.437 | 0.252 |
A:P09622:0.253 |
HOH |
7.385 |
O |
O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 124.0 | 0.653 | -147.4 | 113.0 | 88.0 | 0.463 | 0.19 |
B:P09622:0.189 |
HOH |
7.735 |
H |
O |
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GLU | B:102 | B:80 | 126.0 | 0.663 | -147.7 | 114.6 | 91.0 | 0.479 | 0.184 |
A:P09622:0.184 |
HOH |
7.425 |
O |
O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 139.0 | 0.732 | -143.2 | 122.6 | 96.0 | 0.505 | 0.227 |
B:P09622:0.226 |
HOH |
7.595 |
O |
O |
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GLU | B:102 | B:80 | 128.0 | 0.674 | -148.0 | 123.0 | 89.0 | 0.468 | 0.206 |
A:P09622:0.205 |
HOH |
7.511 |
O |
O |
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6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:102 | A:80 | 132.0 | 0.695 | -147.9 | 125.3 | 82.0 | 0.432 | 0.263 |
B:P09622:0.263 |
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GLU | B:102 | B:80 | 173.0 | 0.911 | -154.6 | 136.8 | 151.0 | 0.795 | 0.116 |
A:P09622:0.116 |
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GLU | C:102 | C:80 | 147.0 | 0.774 | -146.2 | 129.7 | NA | NA | NA | ||||||||||||||
GLU | D:102 | D:80 | 139.0 | 0.732 | -149.9 | 129.9 | NA | NA | NA | ||||||||||||||
GLU | E:102 | E:80 | 158.0 | 0.832 | -148.7 | 131.1 | NA | NA | NA | ||||||||||||||
GLU | F:102 | F:80 | 139.0 | 0.732 | -146.6 | 131.5 | NA | NA | NA | ||||||||||||||
GLU | G:102 | G:80 | 156.0 | 0.821 | -145.1 | 130.3 | NA | NA | NA | ||||||||||||||
GLU | H:102 | H:80 | 161.0 | 0.847 | -153.4 | 136.4 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLU | A:115 | A:115 | 131.0 | 0.689 | -140.0 | 136.7 |