Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107545463 . C A CCDS5749.1:NM_000108.3:c.398gCt>gAt_NP_000099.2:p.133A>D Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ALA A:119 A:98 67.0 0.583 H -65.5 -39.0 40.0 0.348 0.235 B:P09622:0.235
 HOH
 3.272
 N
 O
ALA B:119 B:98 67.0 0.583 H -57.3 -46.8 41.0 0.357 0.226 A:P09622:0.226
 HOH
 8.682
 N
 O
ALA C:119 C:98 67.0 0.583 H -67.4 -46.3 NA NA NA
ALA D:119 D:98 68.0 0.591 H -60.9 -38.7 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ALA A:98 A:98 63.0 0.548 H -63.8 -37.4 39.0 0.339 0.209 B:P09622:0.209
 HOH
 9.044
 C
 O
ALA B:98 B:98 70.0 0.609 H -60.0 -47.0 44.0 0.383 0.226 A:P09622:0.226
 HOH
 7.796
 N
 O
ALA C:98 C:98 69.0 0.6 H -58.6 -33.6 NA NA NA
ALA D:98 D:98 61.0 0.53 H -57.5 -57.2 NA NA NA
ALA E:98 E:98 65.0 0.565 H -71.4 -38.0 NA NA NA
ALA F:98 F:98 68.0 0.591 H -53.1 -56.3 NA NA NA
ALA G:98 G:98 68.0 0.591 H -66.4 -43.8 NA NA NA
ALA H:98 H:98 64.0 0.557 H -52.8 -62.0 NA NA NA
ALA I:98 I:98 67.0 0.583 H -73.8 -26.6 NA NA NA
ALA J:98 J:98 66.0 0.574 H -30.2 -59.7 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 69.0 0.6 H -63.6 -43.8 42.0 0.365 0.235 B:P09622:0.235
 HOH
 2.728
 HB2
 O
ALA B:120 B:98 69.0 0.6 H -63.5 -43.7 43.0 0.374 0.226 A:P09622:0.226
 HOH
 2.868
 HB2
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 68.0 0.591 H -62.8 -42.9 41.0 0.357 0.234 B:P09622:0.235
 HOH
 4.727
 HB3
 O
ALA B:120 B:98 69.0 0.6 H -63.3 -42.0 44.0 0.383 0.217 A:P09622:0.217
 HOH
 4.231
 O
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ALA A:98 A:98 66.0 0.574 H -57.2 -49.2 42.0 0.365 0.209 B:P09622:0.209
 HOH
 2.756
 O
 O
ALA B:98 B:98 66.0 0.574 H -53.6 -53.2 43.0 0.374 0.2 A:P09622:0.2
 HOH
 5.336
 N
 O
ALA C:98 C:98 66.0 0.574 H -51.9 -54.2 NA NA NA
ALA D:98 D:98 67.0 0.583 H -60.7 -47.6 NA NA NA
ALA E:98 E:98 66.0 0.574 H -68.8 -41.7 NA NA NA
ALA F:98 F:98 70.0 0.609 H -65.8 -33.9 NA NA NA
ALA G:98 G:98 67.0 0.583 H -60.0 -39.5 NA NA NA
ALA H:98 H:98 64.0 0.557 H -65.1 -46.2 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ALA A:98 A:98 66.0 0.574 H -60.5 -50.8 41.0 0.357 0.217 B:P09622:0.217
 HOH
 2.795
 O
 O
ALA B:98 B:98 67.0 0.583 H -62.0 -43.0 43.0 0.374 0.209 A:P09622:0.209
 HOH
 5.987
 N
 O
ALA C:98 C:98 69.0 0.6 H -58.2 -39.6 NA NA NA
ALA D:98 D:98 68.0 0.591 H -61.6 -47.0 NA NA NA
ALA E:98 E:98 70.0 0.609 H -61.4 -42.8 NA NA NA
ALA F:98 F:98 68.0 0.591 H -64.1 -37.6 NA NA NA
ALA G:98 G:98 64.0 0.557 H -65.0 -42.6 NA NA NA
ALA H:98 H:98 66.0 0.574 H -65.4 -39.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ALA A:98 A:98 67.0 0.583 H -65.6 -42.2 42.0 0.365 0.218 B:P09622:0.217
 HOH
 3.287
 CA
 O
ALA B:98 B:98 68.0 0.591 H -68.0 -42.9 42.0 0.365 0.226 A:P09622:0.226
 HOH
 4.717
 O
 O
ALA C:98 C:98 67.0 0.583 H -61.0 -40.6 NA NA NA
ALA D:98 D:98 70.0 0.609 H -61.7 -43.8 NA NA NA
ALA E:98 E:98 68.0 0.591 H -59.8 -45.3 NA NA NA
ALA F:98 F:98 67.0 0.583 H -63.8 -45.0 NA NA NA
ALA G:98 G:98 70.0 0.609 H -60.4 -43.4 NA NA NA
ALA H:98 H:98 67.0 0.583 H -63.8 -39.0 NA NA NA
ALA I:98 I:98 67.0 0.583 H -58.6 -45.6 NA NA NA
ALA J:98 J:98 69.0 0.6 H -60.5 -44.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ALA A:119 A:98 66.0 0.574 H -62.9 -41.6 38.0 0.33 0.244 B:P09622:0.243
 HOH
 4.688
 HB3
 O
ALA B:119 B:98 68.0 0.591 H -64.6 -41.8 40.0 0.348 0.243 A:P09622:0.243
ALA C:119 C:98 66.0 0.574 H -65.6 -41.8 NA NA NA
ALA D:119 D:98 69.0 0.6 H -64.0 -41.3 NA NA NA
ALA E:119 E:98 67.0 0.583 H -63.9 -42.3 NA NA NA
ALA F:119 F:98 66.0 0.574 H -62.8 -41.5 NA NA NA
ALA G:119 G:98 67.0 0.583 H -65.3 -43.4 NA NA NA
ALA H:119 H:98 64.0 0.557 H -64.1 -42.9 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 67.0 0.583 H -61.5 -43.8 40.0 0.348 0.235 B:P09622:0.235
 HOH
 5.952
 O
 O
ALA B:120 B:98 70.0 0.609 H -61.9 -43.2 50.0 0.435 0.174 A:P09622:0.174
 HOH
 4.969
 HB3
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ALA A:120 A:98 65.0 0.565 H -62.9 -42.7 39.0 0.339 0.226 B:P09622:0.226
 HOH
 4.553
 O
 O
ALA B:120 B:98 68.0 0.591 H -66.7 -41.6 41.0 0.357 0.234 A:P09622:0.235
 HOH
 3.431
 N
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ALA A:120 A:98 68.0 0.591 H -66.7 -39.9 43.0 0.374 0.217 B:P09622:0.217
 HOH
 3.483
 CA
 O
ALA B:120 B:98 69.0 0.6 H -64.1 -41.9 42.0 0.365 0.235 A:P09622:0.235
 HOH
 2.541
 O
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 66.0 0.574 H -62.3 -42.7 40.0 0.348 0.226 B:P09622:0.226
 HOH
 2.695
 O
 O
ALA B:120 B:98 69.0 0.6 H -62.4 -41.9 42.0 0.365 0.235 A:P09622:0.235
 HOH
 2.803
 HA
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 67.0 0.583 H -61.3 -45.7 40.0 0.348 0.235 B:P09622:0.235
 HOH
 2.798
 HA
 O
ALA B:120 B:98 68.0 0.591 H -60.0 -43.7 42.0 0.365 0.226 A:P09622:0.226
 HOH
 2.930
 HA
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 68.0 0.591 H -63.2 -39.6 42.0 0.365 0.226 B:P09622:0.226
 HOH
 2.670
 HB2
 O
ALA B:120 B:98 69.0 0.6 H -60.6 -40.1 42.0 0.365 0.235 A:P09622:0.235
 HOH
 2.621
 HA
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:120 A:98 67.0 0.583 H -71.1 -36.4 43.0 0.374 0.209 B:P09622:0.209
 SO4
HOH
 9.701
2.875
 O
HB2
 O3
O
ALA B:120 B:98 72.0 0.626 H -68.6 -37.4 48.0 0.417 0.209 A:P09622:0.209
 HOH
 7.719
 O
 O
ALA C:120 C:98 66.0 0.574 H -68.1 -36.9 NA NA NA
ALA D:120 D:98 70.0 0.609 H -69.3 -37.5 NA NA NA
ALA E:120 E:98 69.0 0.6 H -69.4 -36.7 NA NA NA
ALA F:120 F:98 70.0 0.609 H -67.0 -37.1 NA NA NA
ALA G:120 G:98 69.0 0.6 H -69.9 -37.7 NA NA NA
ALA H:120 H:98 72.0 0.626 H -68.1 -36.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ALA A:133 A:133 66.0 0.574 H -63.0 -47.3