Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107545485 . C A CCDS5749.1:NM_000108.3:c.420caC>caA_NP_000099.2:p.140H>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 HIS A:126 A:105 119.0 0.61 H -60.0 -43.3 119.0 0.61 0.0 HOH
 3.985
 CE1
 O
HIS B:126 B:105 121.0 0.621 H -56.1 -29.6 121.0 0.621 0.0 HOH
 3.963
 NE2
 O
HIS C:126 C:105 117.0 0.6 H -53.3 -39.6 NA NA NA
HIS D:126 D:105 100.0 0.513 H -57.9 -44.0 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 HIS A:105 A:105 107.0 0.549 H -69.7 -31.7 107.0 0.549 0.0 HOH
 2.727
 CD2
 O
HIS B:105 B:105 114.0 0.585 H -62.1 -42.9 114.0 0.585 0.0 HOH
 7.462
 O
 O
HIS C:105 C:105 106.0 0.544 H -69.6 -39.6 NA NA NA
HIS D:105 D:105 112.0 0.574 H -50.8 -49.2 NA NA NA
HIS E:105 E:105 113.0 0.579 H -80.0 -39.1 NA NA NA
HIS F:105 F:105 106.0 0.544 H -63.5 -31.7 NA NA NA
HIS G:105 G:105 118.0 0.605 H -68.9 -31.9 NA NA NA
HIS H:105 H:105 117.0 0.6 H -58.3 -36.6 NA NA NA
HIS I:105 I:105 117.0 0.6 H -57.8 -47.0 NA NA NA
HIS J:105 J:105 116.0 0.595 H -82.2 -33.5 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 111.0 0.569 H -66.3 -39.5 111.0 0.569 0.0 HOH
 4.761
 N
 O
HIS B:127 B:105 108.0 0.554 H -65.5 -40.4 108.0 0.554 0.0 HOH
 3.663
 HD2
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 110.0 0.564 H -66.8 -39.8 110.0 0.564 0.0 HOH
 4.843
 N
 O
HIS B:127 B:105 116.0 0.595 H -65.1 -38.7 116.0 0.595 0.0 HOH
 3.444
 HE2
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 HIS A:105 A:105 136.0 0.697 H -69.1 -36.3 136.0 0.697 0.0 HOH
 4.893
 N
 O
HIS B:105 B:105 113.0 0.579 H -67.1 -43.5 113.0 0.579 0.0 HOH
 5.679
 CD2
 O
HIS C:105 C:105 109.0 0.559 H -66.7 -42.3 NA NA NA
HIS D:105 D:105 111.0 0.569 H -66.5 -42.1 NA NA NA
HIS E:105 E:105 109.0 0.559 H -66.7 -35.0 NA NA NA
HIS F:105 F:105 141.0 0.723 H -72.9 -39.2 NA NA NA
HIS G:105 G:105 139.0 0.713 H -65.5 -42.4 NA NA NA
HIS H:105 H:105 101.0 0.518 H -64.9 -39.8 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 HIS A:105 A:105 114.0 0.585 H -66.7 -40.0 114.0 0.585 0.0 HOH
 3.432
 CB
 O
HIS B:105 B:105 117.0 0.6 H -65.4 -39.3 117.0 0.6 0.0 HOH
 5.262
 CD2
 O
HIS C:105 C:105 107.0 0.549 H -62.4 -41.3 NA NA NA
HIS D:105 D:105 117.0 0.6 H -63.3 -43.0 NA NA NA
HIS E:105 E:105 107.0 0.549 H -64.2 -34.4 NA NA NA
HIS F:105 F:105 108.0 0.554 H -62.7 -40.1 NA NA NA
HIS G:105 G:105 110.0 0.564 H -65.0 -41.0 NA NA NA
HIS H:105 H:105 109.0 0.559 H -63.1 -39.6 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 HIS A:105 A:105 117.0 0.6 H -65.7 -38.3 117.0 0.6 0.0 HOH
 6.835
 N
 O
HIS B:105 B:105 122.0 0.626 H -49.9 -38.9 122.0 0.626 0.0 HOH
 7.766
 CB
 O
HIS C:105 C:105 111.0 0.569 H -59.9 -44.8 NA NA NA
HIS D:105 D:105 112.0 0.574 H -58.9 -43.5 NA NA NA
HIS E:105 E:105 109.0 0.559 H -64.4 -41.2 NA NA NA
HIS F:105 F:105 118.0 0.605 H -60.8 -41.2 NA NA NA
HIS G:105 G:105 110.0 0.564 H -56.1 -48.4 NA NA NA
HIS H:105 H:105 116.0 0.595 H -67.5 -37.1 NA NA NA
HIS I:105 I:105 121.0 0.621 H -59.3 -38.2 NA NA NA
HIS J:105 J:105 113.0 0.579 H -65.6 -39.0 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 HIS A:126 A:105 120.0 0.615 H -64.8 -39.5 120.0 0.615 0.0
HIS B:126 B:105 104.0 0.533 H -65.0 -39.9 104.0 0.533 0.0
HIS C:126 C:105 108.0 0.554 H -64.6 -42.1 NA NA NA
HIS D:126 D:105 113.0 0.579 H -65.3 -38.3 NA NA NA
HIS E:126 E:105 114.0 0.585 H -65.1 -39.4 NA NA NA
HIS F:126 F:105 118.0 0.605 H -63.4 -39.6 NA NA NA
HIS G:126 G:105 112.0 0.574 H -64.8 -38.0 NA NA NA
HIS H:126 H:105 115.0 0.59 H -64.7 -39.2 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 109.0 0.559 H -66.6 -41.4 109.0 0.559 0.0 HOH
 2.818
 HB2
 O
HIS B:127 B:105 110.0 0.564 H -66.3 -40.5 110.0 0.564 0.0 HOH
 2.749
 HE1
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 HIS A:127 A:105 125.0 0.641 H -69.1 -39.7 125.0 0.641 0.0 HOH
 5.219
 N
 O
HIS B:127 B:105 98.0 0.503 H -59.3 -46.0 98.0 0.503 0.0 HOH
 3.493
 CD2
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 HIS A:127 A:105 106.0 0.544 H -61.5 -48.7 106.0 0.544 0.0 HOH
 3.297
 CD2
 O
HIS B:127 B:105 103.0 0.528 H -64.3 -40.7 103.0 0.528 0.0 HOH
 2.685
 ND1
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 104.0 0.533 H -68.2 -40.4 104.0 0.533 0.0 HOH
 4.898
 N
 O
HIS B:127 B:105 114.0 0.585 H -64.1 -39.0 114.0 0.585 0.0 HOH
 2.806
 HD2
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 112.0 0.574 H -70.0 -40.1 112.0 0.574 0.0 HOH
 4.838
 N
 O
HIS B:127 B:105 118.0 0.605 H -64.4 -39.7 118.0 0.605 0.0 HOH
 3.344
 HB2
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 129.0 0.662 H -66.0 -42.9 129.0 0.662 0.0 HOH
 4.887
 N
 O
HIS B:127 B:105 114.0 0.585 H -62.3 -43.5 114.0 0.585 0.0 HOH
 3.259
 HE2
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 HIS A:127 A:105 106.0 0.544 H -66.4 -37.8 106.0 0.544 0.0 SO4
HOH
 1.664
2.820
 HD1
HA
 O3
O
HIS B:127 B:105 106.0 0.544 H -65.2 -36.7 103.0 0.528 0.016 A:P09622:0.015
 HOH
 6.608
 H
 O
HIS C:127 C:105 111.0 0.569 H -67.0 -37.9 NA NA NA
HIS D:127 D:105 114.0 0.585 H -65.1 -37.2 NA NA NA
HIS E:127 E:105 139.0 0.713 H -69.9 -38.5 NA NA NA
HIS F:127 F:105 114.0 0.585 H -68.4 -37.7 NA NA NA
HIS G:127 G:105 128.0 0.656 H -70.6 -38.2 NA NA NA
HIS H:127 H:105 122.0 0.626 H -66.5 -38.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 HIS A:140 A:140 118.0 0.605 H -67.0 -46.7