Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107545888 . T A CCDS5749.1:NM_000108.3:c.521aTt>aAt_NP_000099.2:p.174I>N Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ILE A:160 A:139 0.0 0.0 E -133.7 115.0 0.0 0.0 0.0 FAD
HOH
 9.857
9.307
 CD1
CD1
 C2A
O
ILE B:160 B:139 2.0 0.011 E -127.3 123.0 2.0 0.011 0.0
ILE C:160 C:139 0.0 0.0 E -127.0 121.7 NA NA NA
ILE D:160 D:139 0.0 0.0 E -132.4 118.2 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ILE A:139 A:139 0.0 0.0 E -110.6 123.7 0.0 0.0 0.0 FAD
 9.967
 CD1
 N1A
ILE B:139 B:139 0.0 0.0 E -126.0 109.6 0.0 0.0 0.0
ILE C:139 C:139 0.0 0.0 E -125.9 118.6 NA NA NA
ILE D:139 D:139 0.0 0.0 E -131.1 114.3 NA NA NA
ILE E:139 E:139 0.0 0.0 E -109.7 117.5 NA NA NA
ILE F:139 F:139 0.0 0.0 E -103.1 119.6 NA NA NA
ILE G:139 G:139 0.0 0.0 E -113.7 137.8 NA NA NA
ILE H:139 H:139 0.0 0.0 E -132.8 119.5 NA NA NA
ILE I:139 I:139 1.0 0.006 E -141.0 123.1 NA NA NA
ILE J:139 J:139 0.0 0.0 E -125.5 119.3 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -120.7 117.5 0.0 0.0 0.0 FAD
HOH
 8.484
5.664
 HD13
O
 H2A
O
ILE B:161 B:139 0.0 0.0 E -117.8 114.7 0.0 0.0 0.0 FAD
HOH
 8.509
5.853
 HD13
N
 H2A
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -117.4 114.4 0.0 0.0 0.0 FAD
HOH
 8.681
5.807
 HD13
N
 H2A
O
ILE B:161 B:139 0.0 0.0 E -116.6 113.5 0.0 0.0 0.0 FAD
HOH
 8.623
6.396
 HD13
HG23
 H2A
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:139 A:139 0.0 0.0 E -129.4 111.7 0.0 0.0 0.0 FAD
HOH
 9.571
5.764
 CD1
N
 C2A
O
ILE B:139 B:139 1.0 0.006 E -138.6 117.7 1.0 0.006 0.0
ILE C:139 C:139 1.0 0.006 E -133.7 119.4 NA NA NA
ILE D:139 D:139 0.0 0.0 E -126.2 114.6 NA NA NA
ILE E:139 E:139 0.0 0.0 E -129.7 125.3 NA NA NA
ILE F:139 F:139 0.0 0.0 E -130.1 115.1 NA NA NA
ILE G:139 G:139 0.0 0.0 E -134.1 117.0 NA NA NA
ILE H:139 H:139 0.0 0.0 E -121.3 129.8 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:139 A:139 1.0 0.006 E -130.0 114.5 1.0 0.006 0.0 FAD
HOH
 9.836
5.665
 CD1
N
 C2A
O
ILE B:139 B:139 0.0 0.0 E -133.6 116.3 0.0 0.0 0.0 FAD
 9.924
 CD1
 C2A
ILE C:139 C:139 0.0 0.0 E -129.7 116.8 NA NA NA
ILE D:139 D:139 0.0 0.0 E -123.6 115.3 NA NA NA
ILE E:139 E:139 0.0 0.0 E -121.9 126.1 NA NA NA
ILE F:139 F:139 0.0 0.0 E -125.2 116.4 NA NA NA
ILE G:139 G:139 0.0 0.0 E -125.7 118.9 NA NA NA
ILE H:139 H:139 0.0 0.0 E -121.1 126.3 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ILE A:139 A:139 0.0 0.0 E -132.8 117.7 0.0 0.0 0.0 HOH
 8.634
 CG2
 O
ILE B:139 B:139 0.0 0.0 E -130.0 109.9 0.0 0.0 0.0
ILE C:139 C:139 0.0 0.0 E -123.8 122.6 NA NA NA
ILE D:139 D:139 0.0 0.0 E -131.2 119.4 NA NA NA
ILE E:139 E:139 0.0 0.0 E -126.1 118.8 NA NA NA
ILE F:139 F:139 0.0 0.0 E -126.5 127.6 NA NA NA
ILE G:139 G:139 0.0 0.0 E -130.7 118.0 NA NA NA
ILE H:139 H:139 0.0 0.0 E -121.9 126.2 NA NA NA
ILE I:139 I:139 0.0 0.0 E -126.8 117.1 NA NA NA
ILE J:139 J:139 0.0 0.0 E -127.5 122.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ILE A:160 A:139 0.0 0.0 E -123.8 122.8 0.0 0.0 0.0 FAD
HOH
 8.651
8.297
 HD11
HD11
 H2A
O
ILE B:160 B:139 0.0 0.0 E -123.3 122.6 0.0 0.0 0.0 FAD
 8.675
 HD13
 H2A
ILE C:160 C:139 0.0 0.0 E -121.3 123.9 NA NA NA
ILE D:160 D:139 0.0 0.0 E -124.8 124.7 NA NA NA
ILE E:160 E:139 0.0 0.0 E -124.6 120.3 NA NA NA
ILE F:160 F:139 1.0 0.006 E -127.1 125.2 NA NA NA
ILE G:160 G:139 0.0 0.0 E -120.1 120.6 NA NA NA
ILE H:160 H:139 0.0 0.0 E -125.4 123.8 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -117.4 114.8 0.0 0.0 0.0 FAD
HOH
 8.594
5.727
 HD13
N
 H2A
O
ILE B:161 B:139 0.0 0.0 E -116.3 113.4 0.0 0.0 0.0 FAD
HOH
 8.574
7.183
 HD13
O
 H2A
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ILE A:161 A:139 0.0 0.0 E -119.7 124.7 0.0 0.0 0.0 FAD
HOH
 9.766
5.235
 CD1
O
 N1A
O
ILE B:161 B:139 0.0 0.0 E -117.4 119.5 0.0 0.0 0.0 FAD
HOH
 9.715
6.903
 CD1
O
 N1A
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ILE A:161 A:139 0.0 0.0 E -121.5 122.9 0.0 0.0 0.0 FAD
HOH
 9.952
5.345
 CD1
O
 N1A
O
ILE B:161 B:139 0.0 0.0 E -117.1 117.9 0.0 0.0 0.0 FAD
HOH
 9.716
6.839
 CD1
C
 N1A
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -121.7 116.7 0.0 0.0 0.0 FAD
HOH
 8.791
5.553
 HD13
O
 H2A
O
ILE B:161 B:139 0.0 0.0 E -120.3 114.6 0.0 0.0 0.0 FAD
HOH
 8.754
5.394
 HD11
O
 H2A
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -119.4 119.1 0.0 0.0 0.0 FAD
HOH
 8.767
5.516
 HD13
O
 H2A
O
ILE B:161 B:139 0.0 0.0 E -117.8 113.1 0.0 0.0 0.0 FAD
HOH
 8.688
6.533
 HD12
HG23
 H2A
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -119.7 115.7 0.0 0.0 0.0 FAD
HOH
 8.637
5.505
 HD13
O
 H2A
O
ILE B:161 B:139 0.0 0.0 E -116.3 114.5 0.0 0.0 0.0 FAD
HOH
 8.624
5.611
 HD13
O
 H2A
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:161 A:139 0.0 0.0 E -123.3 122.5 0.0 0.0 0.0 FAD
HOH
 9.129
5.361
 HD13
O
 H2A
O
ILE B:161 B:139 2.0 0.011 E -128.4 133.2 2.0 0.011 0.0
ILE C:161 C:139 0.0 0.0 E -122.5 121.1 NA NA NA
ILE D:161 D:139 14.0 0.08 E -121.3 129.2 NA NA NA
ILE E:161 E:139 7.0 0.04 E -124.9 120.7 NA NA NA
ILE F:161 F:139 0.0 0.0 E -122.0 121.1 NA NA NA
ILE G:161 G:139 0.0 0.0 E -121.6 121.7 NA NA NA
ILE H:161 H:139 0.0 0.0 E -123.2 122.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ILE A:174 A:174 0.0 0.0 E -125.3 112.3