Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107545896 . A C CCDS5749.1:NM_000108.3:c.529Aag>Cag_NP_000099.2:p.177K>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
2011-05-04 LYS A:163 A:142 117.0 0.585 E -74.9 -53.0 117.0 0.585 0.0
LYS B:163 B:142 112.0 0.56 E -75.4 -30.0 112.0 0.56 0.0
LYS C:163 C:142 126.0 0.63 E -68.9 -45.5 NA NA NA
LYS D:163 D:142 97.0 0.485 E -77.6 -36.3 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
2005-11-15 LYS A:142 A:142 135.0 0.675 E -80.4 -41.7 135.0 0.675 0.0
LYS B:142 B:142 131.0 0.655 E -67.4 -63.6 131.0 0.655 0.0 HOH
5.941
O
O
LYS C:142 C:142 134.0 0.67 E -75.5 -48.6 NA NA NA
LYS D:142 D:142 128.0 0.64 E -68.8 -34.5 NA NA NA
LYS E:142 E:142 135.0 0.675 E -67.0 -60.6 NA NA NA
LYS F:142 F:142 146.0 0.73 E -69.0 -41.2 NA NA NA
LYS G:142 G:142 123.0 0.615 S -90.0 -3.5 NA NA NA
LYS H:142 H:142 131.0 0.655 E -64.4 -48.0 NA NA NA
LYS I:142 I:142 122.0 0.61 S -100.2 -29.1 NA NA NA
LYS J:142 J:142 149.0 0.745 S -57.2 -68.2 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
2019-11-20 LYS A:164 A:142 132.0 0.66 E -70.1 -51.5 132.0 0.66 0.0 SO4
HOH
5.242
3.344
O
O
O4
O
LYS B:164 B:142 134.0 0.67 E -71.6 -50.4 134.0 0.67 0.0 HOH
3.215
HG3
O
6i4t 1 P09622 99.79 0.0 X-RAY
2019-11-20 LYS A:164 A:142 134.0 0.67 E -72.0 -49.1 134.0 0.67 0.0 HOH
3.509
HZ3
O
LYS B:164 B:142 136.0 0.68 E -71.3 -46.1 136.0 0.68 0.0 HOH
8.236
HA
O
1zmc 1 P09622 99.79 0.0 X-RAY
2005-06-28 LYS A:142 A:142 129.0 0.645 E -68.7 -43.8 129.0 0.645 0.0 HOH
3.411
O
O
LYS B:142 B:142 119.0 0.595 E -81.6 -42.0 119.0 0.595 0.0
LYS C:142 C:142 117.0 0.585 E -76.6 -38.2 NA NA NA
LYS D:142 D:142 128.0 0.64 E -71.9 -36.0 NA NA NA
LYS E:142 E:142 123.0 0.615 E -72.7 -38.4 NA NA NA
LYS F:142 F:142 128.0 0.64 E -69.0 -41.7 NA NA NA
LYS G:142 G:142 129.0 0.645 E -74.8 -38.9 NA NA NA
LYS H:142 H:142 122.0 0.61 E -75.6 -39.5 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
2005-06-28 LYS A:142 A:142 136.0 0.68 E -71.9 -41.8 136.0 0.68 0.0 HOH
3.206
O
O
LYS B:142 B:142 114.0 0.57 E -75.1 -43.8 114.0 0.57 0.0
LYS C:142 C:142 122.0 0.61 E -71.0 -47.9 NA NA NA
LYS D:142 D:142 129.0 0.645 E -69.2 -46.4 NA NA NA
LYS E:142 E:142 124.0 0.62 E -72.6 -38.2 NA NA NA
LYS F:142 F:142 130.0 0.65 E -68.4 -46.2 NA NA NA
LYS G:142 G:142 127.0 0.635 E -70.0 -43.6 NA NA NA
LYS H:142 H:142 127.0 0.635 E -69.8 -50.7 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
2006-01-17 LYS A:142 A:142 134.0 0.67 E -74.0 -48.2 134.0 0.67 0.0 HOH
5.524
NZ
O
LYS B:142 B:142 130.0 0.65 E -74.6 -30.7 130.0 0.65 0.0
LYS C:142 C:142 127.0 0.635 E -68.5 -48.9 NA NA NA
LYS D:142 D:142 126.0 0.63 E -67.2 -42.6 NA NA NA
LYS E:142 E:142 123.0 0.615 E -73.5 -44.6 NA NA NA
LYS F:142 F:142 131.0 0.655 E -57.2 -55.4 NA NA NA
LYS G:142 G:142 127.0 0.635 E -72.4 -44.6 NA NA NA
LYS H:142 H:142 129.0 0.645 E -66.0 -49.9 NA NA NA
LYS I:142 I:142 121.0 0.605 E -65.9 -41.6 NA NA NA
LYS J:142 J:142 124.0 0.62 E -66.3 -51.4 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
2018-05-16 LYS A:163 A:142 126.0 0.63 E -71.1 -45.5 126.0 0.63 0.0
LYS B:163 B:142 138.0 0.69 E -71.2 -43.3 138.0 0.69 0.0
LYS C:163 C:142 131.0 0.655 E -75.3 -46.3 NA NA NA
LYS D:163 D:142 133.0 0.665 E -66.1 -45.2 NA NA NA
LYS E:163 E:142 134.0 0.67 E -66.2 -49.2 NA NA NA
LYS F:163 F:142 124.0 0.62 E -72.0 -44.0 NA NA NA
LYS G:163 G:142 134.0 0.67 E -73.9 -42.9 NA NA NA
LYS H:163 H:142 118.0 0.59 E -73.9 -42.3 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
2019-11-20 LYS A:164 A:142 127.0 0.635 E -70.4 -48.8 127.0 0.635 0.0 HOH
3.300
O
O
LYS B:164 B:142 135.0 0.675 E -70.6 -47.4 135.0 0.675 0.0 HOH
8.237
HA
O
5j5z 1 P09622 99.79 0.0 X-RAY
2017-11-15 LYS A:164 A:142 129.0 0.645 E -61.6 -52.1 129.0 0.645 0.0 HOH
3.968
N
O
LYS B:164 B:142 129.0 0.645 E -68.6 -47.8 129.0 0.645 0.0 HOH
3.985
N
O
6hg8 1 P09622 99.79 0.0 X-RAY
2019-09-04 LYS A:164 A:142 134.0 0.67 E -63.6 -51.7 134.0 0.67 0.0 SO4
HOH
5.228
3.121
O
O
O4
O
LYS B:164 B:142 133.0 0.665 E -73.3 -41.7 133.0 0.665 0.0 HOH
3.028
O
O
6i4r 1 P09622 99.79 0.0 X-RAY
2019-11-20 LYS A:164 A:142 136.0 0.68 E -67.8 -48.4 136.0 0.68 0.0 HOH
3.120
O
O
LYS B:164 B:142 135.0 0.675 E -69.1 -46.6 135.0 0.675 0.0 HOH
3.102
O
O
6i4p 1 P09622 99.79 0.0 X-RAY
2019-11-20 LYS A:164 A:142 132.0 0.66 E -67.9 -49.1 132.0 0.66 0.0 SO4
HOH
5.180
3.100
O
HB3
O3
O
LYS B:164 B:142 134.0 0.67 E -69.2 -49.9 134.0 0.67 0.0 HOH
3.320
HG3
O
6i4s 1 P09622 99.79 0.0 X-RAY
2019-11-20 LYS A:164 A:142 142.0 0.71 E -71.3 -50.1 142.0 0.71 0.0 HOH
3.226
HG3
O
LYS B:164 B:142 140.0 0.7 E -69.8 -48.1 140.0 0.7 0.0 HOH
3.127
HE3
O
6i4z 1 P09622 99.79 0.0 X-RAY
2019-11-20 LYS A:164 A:142 132.0 0.66 E -74.3 -39.6 132.0 0.66 0.0 HOH
2.293
HZ1
O
LYS B:164 B:142 132.0 0.66 E -73.3 -42.8 132.0 0.66 0.0 HOH
3.550
HZ2
O
LYS C:164 C:142 134.0 0.67 E -74.7 -40.4 NA NA NA
LYS D:164 D:142 149.0 0.745 E -72.0 -40.6 NA NA NA
LYS E:164 E:142 132.0 0.66 E -71.9 -38.7 NA NA NA
LYS F:164 F:142 134.0 0.67 E -72.1 -39.5 NA NA NA
LYS G:164 G:142 131.0 0.655 E -72.1 -39.0 NA NA NA
LYS H:164 H:142 135.0 0.675 E -71.5 -39.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:177 A:177 129.0 0.645 E -70.0 -47.1