Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107545930 . C A CCDS5749.1:NM_000108.3:c.563aCt>aAt_NP_000099.2:p.188T>N Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 THR A:174 A:153 35.0 0.25 -78.6 118.7 35.0 0.25 0.0 BME
FAD
HOH
 6.066
9.093
2.816
 N
N
O
 O1
C8M
O
THR B:174 B:153 28.0 0.2 -81.1 114.0 28.0 0.2 0.0 BME
FAD
 5.382
8.996
 N
N
 C1
C8M
THR C:174 C:153 34.0 0.243 -80.6 112.9 NA NA NA
THR D:174 D:153 32.0 0.229 -74.1 118.4 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 THR A:153 A:153 34.0 0.243 -72.2 122.5 34.0 0.243 0.0 FAD
HOH
 9.535
5.471
 N
N
 C8M
O
THR B:153 B:153 33.0 0.236 -74.5 115.8 33.0 0.236 0.0 FAD
HOH
 9.653
2.786
 N
O
 C8M
O
THR C:153 C:153 33.0 0.236 -61.3 117.2 NA NA NA
THR D:153 D:153 32.0 0.229 -85.0 116.8 NA NA NA
THR E:153 E:153 33.0 0.236 -77.3 112.9 NA NA NA
THR F:153 F:153 29.0 0.207 -89.1 122.0 NA NA NA
THR G:153 G:153 32.0 0.229 E -86.0 119.3 NA NA NA
THR H:153 H:153 32.0 0.229 -75.9 130.3 NA NA NA
THR I:153 I:153 34.0 0.243 -76.5 108.9 NA NA NA
THR J:153 J:153 32.0 0.229 -65.9 115.6 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 THR A:175 A:153 34.0 0.243 -83.4 116.8 34.0 0.243 0.0 FAD
BTB
SO4
HOH
 7.550
7.175
6.007
2.037
 H
N
HG23
HG1
 HM83
HO1
O3
O
THR B:175 B:153 32.0 0.229 -83.8 119.1 32.0 0.229 0.0 FAD
BTB
HOH
 7.647
8.105
1.868
 H
N
HG1
 HM82
HO1
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:175 A:153 33.0 0.236 -80.7 120.0 33.0 0.236 0.0 FAD
HOH
 7.677
1.886
 H
HG1
 HM83
O
THR B:175 B:153 33.0 0.236 -80.9 122.5 33.0 0.236 0.0 FAD
HOH
 7.810
2.873
 H
O
 HM82
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 THR A:153 A:153 34.0 0.243 -80.2 125.5 34.0 0.243 0.0 FAD
NAD
HOH
 8.822
4.265
4.814
 N
OG1
N
 C8M
O2D
O
THR B:153 B:153 34.0 0.243 -78.4 115.4 34.0 0.243 0.0 FAD
NAD
HOH
 9.058
7.121
2.880
 N
OG1
O
 C8M
O1A
O
THR C:153 C:153 31.0 0.221 -84.5 116.8 NA NA NA
THR D:153 D:153 30.0 0.214 -83.3 116.0 NA NA NA
THR E:153 E:153 34.0 0.243 -91.7 135.5 NA NA NA
THR F:153 F:153 32.0 0.229 -80.6 125.2 NA NA NA
THR G:153 G:153 34.0 0.243 -83.5 120.3 NA NA NA
THR H:153 H:153 30.0 0.214 -88.9 123.3 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 THR A:153 A:153 36.0 0.257 -83.6 120.0 36.0 0.257 0.0 FAD
NAI
HOH
 8.819
6.734
2.707
 N
N
OG1
 C8M
O2N
O
THR B:153 B:153 30.0 0.214 -89.0 117.7 30.0 0.214 0.0 FAD
NAI
HOH
 8.896
6.769
2.682
 N
N
O
 C8M
O2N
O
THR C:153 C:153 32.0 0.229 -92.7 117.9 NA NA NA
THR D:153 D:153 32.0 0.229 -85.4 116.4 NA NA NA
THR E:153 E:153 32.0 0.229 -87.8 122.2 NA NA NA
THR F:153 F:153 32.0 0.229 -83.6 125.6 NA NA NA
THR G:153 G:153 34.0 0.243 -89.0 121.8 NA NA NA
THR H:153 H:153 31.0 0.221 -86.7 121.7 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 THR A:153 A:153 33.0 0.236 -79.6 113.5 33.0 0.236 0.0 FAD
HOH
 8.755
2.379
 N
OG1
 C8M
O
THR B:153 B:153 33.0 0.236 -84.6 115.2 33.0 0.236 0.0 FAD
HOH
 8.883
2.860
 N
O
 C8M
O
THR C:153 C:153 32.0 0.229 -81.8 121.6 NA NA NA
THR D:153 D:153 32.0 0.229 -85.1 117.6 NA NA NA
THR E:153 E:153 35.0 0.25 -92.7 117.3 NA NA NA
THR F:153 F:153 34.0 0.243 -88.3 124.2 NA NA NA
THR G:153 G:153 36.0 0.257 -89.0 117.2 NA NA NA
THR H:153 H:153 33.0 0.236 -81.9 116.3 NA NA NA
THR I:153 I:153 35.0 0.25 -86.8 122.0 NA NA NA
THR J:153 J:153 34.0 0.243 -85.3 122.0 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 THR A:174 A:153 35.0 0.25 -79.1 119.9 35.0 0.25 0.0 FAD
TRS
HOH
 8.019
9.009
4.778
 H
N
H
 HM81
N
O
THR B:174 B:153 32.0 0.229 -83.2 115.3 32.0 0.229 0.0 FAD
HOH
 7.759
2.903
 H
O
 HM81
O
THR C:174 C:153 32.0 0.229 -82.5 117.7 NA NA NA
THR D:174 D:153 39.0 0.279 -81.4 115.5 NA NA NA
THR E:174 E:153 33.0 0.236 -80.7 116.0 NA NA NA
THR F:174 F:153 31.0 0.221 -80.4 114.7 NA NA NA
THR G:174 G:153 32.0 0.229 -80.7 117.7 NA NA NA
THR H:174 H:153 36.0 0.257 -81.1 116.5 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:175 A:153 32.0 0.229 -81.4 119.5 32.0 0.229 0.0 FAD
HOH
 7.718
1.976
 H
HG1
 HM83
O
THR B:175 B:153 32.0 0.229 -82.8 120.2 32.0 0.229 0.0 FAD
HOH
 7.798
2.873
 H
O
 HM82
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 THR A:175 A:153 34.0 0.243 -78.5 119.9 34.0 0.243 0.0 FAD
HOH
 9.147
2.674
 N
OG1
 C8M
O
THR B:175 B:153 30.0 0.214 -83.1 123.7 30.0 0.214 0.0 FAD
HOH
 9.156
2.581
 N
OG1
 C8M
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 THR A:175 A:153 37.0 0.264 -79.5 118.0 37.0 0.264 0.0 FAD
HOH
 9.026
2.726
 N
OG1
 C8M
O
THR B:175 B:153 33.0 0.236 -88.6 122.8 33.0 0.236 0.0 FAD
SO4
HOH
 9.163
7.783
2.582
 N
OG1
OG1
 C8M
O1
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:175 A:153 33.0 0.236 -81.4 120.6 33.0 0.236 0.0 FAD
BTB
HOH
 7.878
7.482
1.947
 H
N
HG1
 HM81
HO1
O
THR B:175 B:153 32.0 0.229 -81.0 120.7 32.0 0.229 0.0 FAD
BTB
HOH
 7.973
7.492
1.935
 H
N
HG1
 HM82
HO4
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:175 A:153 33.0 0.236 -82.4 117.8 33.0 0.236 0.0 FAD
BTB
HOH
 7.887
7.307
1.952
 H
N
HG1
 HM81
HO3
O
THR B:175 B:153 32.0 0.229 -84.0 119.7 32.0 0.229 0.0 FAD
BTB
HOH
 8.058
7.455
1.922
 H
N
HG1
 HM83
HO4
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:175 A:153 33.0 0.236 -84.1 118.3 33.0 0.236 0.0 FAD
SO4
HOH
 7.671
5.936
1.947
 H
HG23
HG1
 HM83
O1
O
THR B:175 B:153 32.0 0.229 -83.8 118.5 32.0 0.229 0.0 FAD
SO4
HOH
 7.990
5.957
2.050
 H
N
HG1
 HM82
O4
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:175 A:153 33.0 0.236 -82.9 121.9 33.0 0.236 0.0 FAD
HOH
 7.734
1.842
 H
HG1
 HM83
O
THR B:175 B:153 21.0 0.15 -88.1 115.0 21.0 0.15 0.0 FAD
 7.597
 H
 HM83
THR C:175 C:153 33.0 0.236 -83.6 120.3 NA NA NA
THR D:175 D:153 26.0 0.186 -88.3 118.7 NA NA NA
THR E:175 E:153 31.0 0.221 -85.0 120.5 NA NA NA
THR F:175 F:153 39.0 0.279 -87.4 119.1 NA NA NA
THR G:175 G:153 26.0 0.186 -89.2 119.5 NA NA NA
THR H:175 H:153 34.0 0.243 -85.6 119.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 THR A:188 A:188 36.0 0.257 -76.4 117.5