Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107546718 . G A CCDS5749.1:NM_000108.3:c.589Gaa>Aaa_NP_000099.2:p.197E>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 GLU A:183 A:162 78.0 0.411 S 50.0 32.2 78.0 0.411 0.0 BME
FAD
HOH
 8.322
9.976
3.802
 OE2
OE2
O
 O1
C8M
O
GLU B:183 B:162 80.0 0.421 S 36.6 46.8 80.0 0.421 0.0 BME
HOH
 8.267
5.836
 OE2
C
 C2
O
GLU C:183 C:162 84.0 0.442 S 50.4 28.4 NA NA NA
GLU D:183 D:162 84.0 0.442 S 53.3 24.5 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 GLU A:162 A:162 77.0 0.405 S 62.8 21.1 77.0 0.405 0.0 HOH
 6.903
 OE2
 O
GLU B:162 B:162 70.0 0.368 S 60.6 28.0 70.0 0.368 0.0 HOH
 5.428
 OE1
 O
GLU C:162 C:162 82.0 0.432 S 63.2 18.0 NA NA NA
GLU D:162 D:162 78.0 0.411 S 56.3 35.7 NA NA NA
GLU E:162 E:162 80.0 0.421 S 55.5 48.8 NA NA NA
GLU F:162 F:162 72.0 0.379 S 66.4 15.8 NA NA NA
GLU G:162 G:162 85.0 0.447 S 62.4 39.0 NA NA NA
GLU H:162 H:162 81.0 0.426 S 49.8 45.8 NA NA NA
GLU I:162 I:162 81.0 0.426 S 54.9 45.3 NA NA NA
GLU J:162 J:162 73.0 0.384 S 42.2 25.6 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 84.0 0.442 S 57.1 23.8 84.0 0.442 0.0 FAD
BTB
HOH
 9.444
6.884
2.631
 OE2
OE2
O
 HM82
H72
O
GLU B:184 B:162 83.0 0.437 S 56.0 24.9 83.0 0.437 0.0 FAD
BTB
HOH
 9.522
7.110
3.458
 OE2
OE2
O
 HM83
HO1
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 83.0 0.437 S 52.9 26.1 83.0 0.437 0.0 FAD
HOH
 9.613
2.802
 OE2
HB3
 HM81
O
GLU B:184 B:162 84.0 0.442 S 51.3 29.4 84.0 0.442 0.0 FAD
HOH
 9.754
3.882
 OE2
O
 HM81
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:162 A:162 80.0 0.421 S 52.1 29.2 80.0 0.421 0.0 FAD
HOH
 9.999
6.356
 OE2
OE2
 C8M
O
GLU B:162 B:162 77.0 0.405 S 59.9 17.2 77.0 0.405 0.0 FAD
HOH
 9.801
6.335
 OE2
N
 C8M
O
GLU C:162 C:162 82.0 0.432 S 53.5 18.6 NA NA NA
GLU D:162 D:162 83.0 0.437 S 53.0 29.5 NA NA NA
GLU E:162 E:162 79.0 0.416 S 56.0 29.9 NA NA NA
GLU F:162 F:162 74.0 0.389 S 64.1 26.6 NA NA NA
GLU G:162 G:162 70.0 0.368 S 66.6 27.5 NA NA NA
GLU H:162 H:162 78.0 0.411 S 62.5 24.8 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:162 A:162 83.0 0.437 S 55.5 18.5 83.0 0.437 0.0 FAD
HOH
 9.833
6.387
 OE2
OE2
 C8M
O
GLU B:162 B:162 79.0 0.416 S 52.9 17.3 79.0 0.416 0.0 FAD
HOH
 9.798
3.497
 OE2
O
 C8M
O
GLU C:162 C:162 80.0 0.421 S 49.2 22.7 NA NA NA
GLU D:162 D:162 83.0 0.437 S 59.4 18.5 NA NA NA
GLU E:162 E:162 80.0 0.421 S 54.6 27.2 NA NA NA
GLU F:162 F:162 78.0 0.411 S 57.6 25.9 NA NA NA
GLU G:162 G:162 78.0 0.411 S 62.0 19.6 NA NA NA
GLU H:162 H:162 78.0 0.411 S 51.8 26.0 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 GLU A:162 A:162 81.0 0.426 S 64.2 21.4 81.0 0.426 0.0 FAD
HOH
 9.981
3.267
 OE2
O
 C8M
O
GLU B:162 B:162 78.0 0.411 S 60.9 33.9 78.0 0.411 0.0 FAD
HOH
 9.876
3.768
 OE2
O
 C8M
O
GLU C:162 C:162 82.0 0.432 S 53.3 24.5 NA NA NA
GLU D:162 D:162 83.0 0.437 S 59.6 24.5 NA NA NA
GLU E:162 E:162 82.0 0.432 S 61.1 31.2 NA NA NA
GLU F:162 F:162 84.0 0.442 S 58.4 28.6 NA NA NA
GLU G:162 G:162 84.0 0.442 S 57.1 27.7 NA NA NA
GLU H:162 H:162 80.0 0.421 S 56.0 28.1 NA NA NA
GLU I:162 I:162 78.0 0.411 S 55.8 27.2 NA NA NA
GLU J:162 J:162 82.0 0.432 S 48.9 23.9 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 GLU A:183 A:162 84.0 0.442 S 56.8 22.4 84.0 0.442 0.0 FAD
TRS
HOH
 9.632
8.344
3.680
 OE2
OE2
O
 HM83
N
O
GLU B:183 B:162 75.0 0.395 S 58.9 27.8 75.0 0.395 0.0 FAD
HOH
 9.704
3.634
 OE2
O
 HM82
O
GLU C:183 C:162 82.0 0.432 S 56.3 24.8 NA NA NA
GLU D:183 D:162 83.0 0.437 S 56.0 25.7 NA NA NA
GLU E:183 E:162 84.0 0.442 S 57.3 26.5 NA NA NA
GLU F:183 F:162 79.0 0.416 S 58.3 26.0 NA NA NA
GLU G:183 G:162 85.0 0.447 S 56.8 23.4 NA NA NA
GLU H:183 H:162 76.0 0.4 S 56.6 28.8 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 84.0 0.442 S 54.2 26.2 84.0 0.442 0.0 FAD
HOH
 9.656
3.594
 OE2
O
 HM82
O
GLU B:184 B:162 83.0 0.437 S 54.2 27.2 83.0 0.437 0.0 FAD
HOH
 9.676
3.737
 OE2
O
 HM81
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 GLU A:184 A:162 84.0 0.442 S 57.6 27.8 84.0 0.442 0.0 HOH
 2.680
 O
 O
GLU B:184 B:162 81.0 0.426 S 61.9 26.7 81.0 0.426 0.0 HOH
 2.606
 OE2
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 GLU A:184 A:162 85.0 0.447 S 55.4 27.2 85.0 0.447 0.0 HOH
 2.662
 O
 O
GLU B:184 B:162 84.0 0.442 S 55.0 27.8 84.0 0.442 0.0 HOH
 2.559
 OE2
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 85.0 0.447 S 57.8 23.0 85.0 0.447 0.0 FAD
BTB
HOH
 9.576
6.902
2.659
 OE2
OE2
O
 HM83
H12
O
GLU B:184 B:162 83.0 0.437 S 56.1 24.0 83.0 0.437 0.0 FAD
BTB
HOH
 9.681
7.165
2.713
 OE2
OE2
OE2
 HM83
H42
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 85.0 0.447 S 55.3 23.8 85.0 0.447 0.0 FAD
BTB
HOH
 9.627
6.424
2.795
 OE2
OE2
O
 HM82
O6
O
GLU B:184 B:162 81.0 0.426 S 55.0 22.6 81.0 0.426 0.0 FAD
BTB
HOH
 9.751
7.232
3.393
 OE2
OE2
O
 HM81
H42
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 81.0 0.426 S 58.7 23.4 81.0 0.426 0.0 FAD
HOH
 9.351
2.688
 OE2
O
 HM82
O
GLU B:184 B:162 82.0 0.432 S 56.5 24.6 82.0 0.432 0.0 FAD
SO4
HOH
 9.724
5.127
2.817
 OE2
OE2
HB3
 HM83
O2
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:184 A:162 82.0 0.432 S 58.7 25.4 82.0 0.432 0.0 FAD
HOH
 9.577
3.686
 OE2
O
 HM82
O
GLU B:184 B:162 78.0 0.411 S 57.5 24.5 78.0 0.411 0.0 FAD
 9.650
 OE2
 HM82
GLU C:184 C:162 85.0 0.447 S 57.2 25.1 NA NA NA
GLU D:184 D:162 83.0 0.437 S 58.7 24.6 NA NA NA
GLU E:184 E:162 66.0 0.347 S 57.9 24.9 NA NA NA
GLU F:184 F:162 85.0 0.447 S 58.8 24.7 NA NA NA
GLU G:184 G:162 88.0 0.463 S 59.1 24.3 NA NA NA
GLU H:184 H:162 85.0 0.447 S 59.0 25.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 GLU A:197 A:197 84.0 0.442 S 58.9 24.4