Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107546761 . A C CCDS5749.1:NM_000108.3:c.632aAa>aCa_NP_000099.2:p.211K>T Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 LYS A:197 A:176 163.0 0.815 S -156.0 156.8 163.0 0.815 0.0 HOH
 2.878
 O
 O
LYS B:197 B:176 162.0 0.81 S -146.5 156.4 162.0 0.81 0.0
LYS C:197 C:176 166.0 0.83 S -144.6 166.3 NA NA NA
LYS D:197 D:176 148.0 0.74 S -158.3 157.2 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 LYS A:176 A:176 148.0 0.74 S -159.0 161.5 148.0 0.74 0.0 HOH
 2.942
 O
 O
LYS B:176 B:176 139.0 0.695 S -153.8 160.9 139.0 0.695 0.0
LYS C:176 C:176 153.0 0.765 S -173.0 156.8 NA NA NA
LYS D:176 D:176 152.0 0.76 S -163.6 138.0 NA NA NA
LYS E:176 E:176 143.0 0.715 S -157.2 146.7 NA NA NA
LYS F:176 F:176 163.0 0.815 S -153.5 146.8 NA NA NA
LYS G:176 G:176 142.0 0.71 S 179.8 159.9 NA NA NA
LYS H:176 H:176 155.0 0.775 S -159.6 158.2 NA NA NA
LYS I:176 I:176 131.0 0.655 S -161.3 148.2 NA NA NA
LYS J:176 J:176 145.0 0.725 S -162.2 150.5 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 159.0 0.795 S -156.1 157.3 159.0 0.795 0.0 HOH
 2.580
 O
 O
LYS B:198 B:176 154.0 0.77 S -154.9 157.9 154.0 0.77 0.0 HOH
 2.787
 O
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 152.0 0.76 S -142.5 158.8 152.0 0.76 0.0 HOH
 2.365
 HZ2
 O
LYS B:198 B:176 165.0 0.825 S -144.3 159.4 165.0 0.825 0.0 HOH
 2.676
 O
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:176 A:176 131.0 0.655 S -154.3 160.7 131.0 0.655 0.0 HOH
 2.664
 O
 O
LYS B:176 B:176 162.0 0.81 S -140.6 144.8 162.0 0.81 0.0 HOH
 7.027
 NZ
 O
LYS C:176 C:176 174.0 0.87 S -138.9 151.8 NA NA NA
LYS D:176 D:176 171.0 0.855 S -136.0 156.1 NA NA NA
LYS E:176 E:176 170.0 0.85 S -163.8 165.5 NA NA NA
LYS F:176 F:176 143.0 0.715 S -150.3 162.3 NA NA NA
LYS G:176 G:176 138.0 0.69 S -143.8 161.5 NA NA NA
LYS H:176 H:176 158.0 0.79 S -164.9 164.1 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:176 A:176 122.0 0.61 S -152.3 160.4 122.0 0.61 0.0 HOH
 2.711
 O
 O
LYS B:176 B:176 166.0 0.83 S -143.3 150.6 166.0 0.83 0.0 HOH
 2.452
 O
 O
LYS C:176 C:176 174.0 0.87 S -139.9 155.9 NA NA NA
LYS D:176 D:176 138.0 0.69 S -158.2 158.3 NA NA NA
LYS E:176 E:176 173.0 0.865 S -146.5 163.9 NA NA NA
LYS F:176 F:176 141.0 0.705 S -152.8 158.7 NA NA NA
LYS G:176 G:176 165.0 0.825 S -142.8 156.0 NA NA NA
LYS H:176 H:176 163.0 0.815 S -143.8 160.6 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 LYS A:176 A:176 161.0 0.805 S -160.1 158.7 161.0 0.805 0.0 HOH
 2.944
 O
 O
LYS B:176 B:176 156.0 0.78 S -159.0 164.2 156.0 0.78 0.0 HOH
 2.714
 O
 O
LYS C:176 C:176 131.0 0.655 S -152.5 160.6 NA NA NA
LYS D:176 D:176 155.0 0.775 S -154.0 153.4 NA NA NA
LYS E:176 E:176 167.0 0.835 S -160.5 161.8 NA NA NA
LYS F:176 F:176 142.0 0.71 S -155.1 161.9 NA NA NA
LYS G:176 G:176 162.0 0.81 S -159.5 162.4 NA NA NA
LYS H:176 H:176 156.0 0.78 S -162.1 159.6 NA NA NA
LYS I:176 I:176 149.0 0.745 S -154.8 157.5 NA NA NA
LYS J:176 J:176 144.0 0.72 S -152.4 153.5 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 LYS A:197 A:176 135.0 0.675 S -144.6 155.6 135.0 0.675 0.0 HOH
 2.229
 HZ3
 O
LYS B:197 B:176 126.0 0.63 S -147.3 158.6 126.0 0.63 0.0 HOH
 2.207
 HZ3
 O
LYS C:197 C:176 150.0 0.75 S -148.6 158.9 NA NA NA
LYS D:197 D:176 140.0 0.7 S -148.3 155.9 NA NA NA
LYS E:197 E:176 167.0 0.835 S -147.2 157.3 NA NA NA
LYS F:197 F:176 127.0 0.635 S -146.9 155.0 NA NA NA
LYS G:197 G:176 132.0 0.66 S -147.5 156.9 NA NA NA
LYS H:197 H:176 142.0 0.71 S -147.6 157.7 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 167.0 0.835 S -151.0 158.4 167.0 0.835 0.0 HOH
 2.676
 O
 O
LYS B:198 B:176 156.0 0.78 S -154.4 157.5 156.0 0.78 0.0 HOH
 2.680
 O
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 LYS A:198 A:176 147.0 0.735 S -153.3 154.4 147.0 0.735 0.0 HOH
 2.645
 O
 O
LYS B:198 B:176 163.0 0.815 S -144.9 158.6 163.0 0.815 0.0 HOH
 3.284
 CB
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 LYS A:198 A:176 156.0 0.78 S -152.0 165.9 156.0 0.78 0.0 HOH
 2.735
 O
 O
LYS B:198 B:176 166.0 0.83 S -151.2 160.5 166.0 0.83 0.0 HOH
 2.625
 O
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 166.0 0.83 S -148.8 157.8 166.0 0.83 0.0 HOH
 2.619
 HE3
 O
LYS B:198 B:176 162.0 0.81 S -150.8 158.1 162.0 0.81 0.0 HOH
 2.620
 HE3
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 166.0 0.83 S -146.5 156.6 166.0 0.83 0.0 HOH
 1.956
 HZ1
 O
LYS B:198 B:176 148.0 0.74 S -150.4 157.6 148.0 0.74 0.0 HOH
 1.825
 HZ3
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 168.0 0.84 S -143.3 157.4 168.0 0.84 0.0 HOH
 2.315
 HE3
 O
LYS B:198 B:176 155.0 0.775 S -148.4 156.5 155.0 0.775 0.0 HOH
 2.543
 HZ1
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:198 A:176 170.0 0.85 S -142.1 149.3 170.0 0.85 0.0 HOH
 2.854
 O
 O
LYS B:198 B:176 150.0 0.75 S -147.3 155.5 150.0 0.75 0.0 HOH
 2.682
 HZ3
 O
LYS C:198 C:176 164.0 0.82 S -147.3 154.7 NA NA NA
LYS D:198 D:176 139.0 0.695 S -146.1 149.1 NA NA NA
LYS E:198 E:176 163.0 0.815 S -140.8 145.8 NA NA NA
LYS F:198 F:176 153.0 0.765 S -146.5 155.4 NA NA NA
LYS G:198 G:176 153.0 0.765 S -139.8 144.9 NA NA NA
LYS H:198 H:176 124.0 0.62 S -150.9 158.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:211 A:211 163.0 0.815 S -149.5 155.6