Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107555951 . G A CCDS5749.1:NM_000108.3:c.685Ggt>Agt_NP_000099.2:p.229G>S Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 GLY A:215 A:194 0.0 0.0 H -62.3 -48.4 0.0 0.0 0.0 BME
FAD
HOH
 8.923
9.595
5.452
 N
N
O
 S2
C7M
O
GLY B:215 B:194 0.0 0.0 H -63.4 -48.6 0.0 0.0 0.0 BME
FAD
HOH
 9.903
9.766
5.294
 N
N
O
 S2
C7M
O
GLY C:215 C:194 0.0 0.0 H -65.0 -36.6 NA NA NA
GLY D:215 D:194 0.0 0.0 H -60.9 -43.0 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 GLY A:194 A:194 0.0 0.0 H -66.1 -39.4 0.0 0.0 0.0 FAD
HOH
 9.139
7.286
 N
O
 C7M
O
GLY B:194 B:194 0.0 0.0 H -71.8 -36.9 0.0 0.0 0.0 FAD
HOH
 9.288
6.146
 N
C
 C7M
O
GLY C:194 C:194 0.0 0.0 H -55.1 -34.0 NA NA NA
GLY D:194 D:194 0.0 0.0 H -51.8 -39.0 NA NA NA
GLY E:194 E:194 0.0 0.0 H -64.6 -38.5 NA NA NA
GLY F:194 F:194 0.0 0.0 H -35.3 -51.7 NA NA NA
GLY G:194 G:194 0.0 0.0 H -53.0 -52.2 NA NA NA
GLY H:194 H:194 0.0 0.0 H -62.3 -34.8 NA NA NA
GLY I:194 I:194 0.0 0.0 H -67.6 -40.8 NA NA NA
GLY J:194 J:194 0.0 0.0 H -64.5 -35.2 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 GLY A:216 A:194 0.0 0.0 H -62.6 -39.4 0.0 0.0 0.0 FAD
HOH
 8.359
5.357
 H
O
 HM73
O
GLY B:216 B:194 0.0 0.0 H -63.2 -39.4 0.0 0.0 0.0 FAD
HOH
 8.395
5.384
 H
O
 HM73
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:216 A:194 0.0 0.0 H -58.4 -41.3 0.0 0.0 0.0 FAD
HOH
 8.836
5.277
 H
O
 HM72
O
GLY B:216 B:194 0.0 0.0 H -59.0 -43.3 0.0 0.0 0.0 FAD
HOH
 8.834
5.518
 H
O
 HM73
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLY A:194 A:194 0.0 0.0 H -54.2 -41.3 0.0 0.0 0.0 FAD
HOH
 9.397
5.748
 N
O
 C7M
O
GLY B:194 B:194 0.0 0.0 H -64.8 -42.3 0.0 0.0 0.0 FAD
HOH
 9.446
7.248
 N
C
 C7M
O
GLY C:194 C:194 0.0 0.0 H -63.7 -38.9 NA NA NA
GLY D:194 D:194 0.0 0.0 H -57.7 -41.6 NA NA NA
GLY E:194 E:194 0.0 0.0 H -56.6 -48.7 NA NA NA
GLY F:194 F:194 0.0 0.0 H -67.2 -43.0 NA NA NA
GLY G:194 G:194 0.0 0.0 H -66.1 -41.1 NA NA NA
GLY H:194 H:194 0.0 0.0 H -57.8 -50.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLY A:194 A:194 0.0 0.0 H -61.9 -38.1 0.0 0.0 0.0 FAD
NAI
HOH
 9.743
9.751
5.522
 N
N
O
 C7M
O1N
O
GLY B:194 B:194 0.0 0.0 H -63.1 -43.4 0.0 0.0 0.0 FAD
NAI
HOH
 9.732
9.778
5.396
 N
N
O
 C7M
O1N
O
GLY C:194 C:194 0.0 0.0 H -61.6 -44.2 NA NA NA
GLY D:194 D:194 0.0 0.0 H -58.5 -37.8 NA NA NA
GLY E:194 E:194 0.0 0.0 H -58.1 -44.0 NA NA NA
GLY F:194 F:194 0.0 0.0 H -62.3 -43.6 NA NA NA
GLY G:194 G:194 0.0 0.0 H -65.3 -36.4 NA NA NA
GLY H:194 H:194 0.0 0.0 H -62.1 -43.5 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 GLY A:194 A:194 0.0 0.0 H -61.6 -46.2 0.0 0.0 0.0 FAD
HOH
 9.565
5.611
 N
O
 C7M
O
GLY B:194 B:194 0.0 0.0 H -68.6 -32.4 0.0 0.0 0.0 FAD
HOH
 9.638
5.427
 N
O
 C7M
O
GLY C:194 C:194 0.0 0.0 H -60.4 -41.5 NA NA NA
GLY D:194 D:194 0.0 0.0 H -65.8 -38.0 NA NA NA
GLY E:194 E:194 0.0 0.0 H -65.0 -37.1 NA NA NA
GLY F:194 F:194 0.0 0.0 H -63.5 -37.3 NA NA NA
GLY G:194 G:194 0.0 0.0 H -66.5 -38.8 NA NA NA
GLY H:194 H:194 0.0 0.0 H -62.6 -43.2 NA NA NA
GLY I:194 I:194 0.0 0.0 H -56.7 -40.8 NA NA NA
GLY J:194 J:194 0.0 0.0 H -56.0 -40.4 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 GLY A:215 A:194 0.0 0.0 H -59.2 -40.1 0.0 0.0 0.0 FAD
HOH
 8.557
5.619
 H
O
 HM71
O
GLY B:215 B:194 0.0 0.0 H -60.1 -39.4 0.0 0.0 0.0 FAD
HOH
 8.833
6.743
 H
H
 HM72
O
GLY C:215 C:194 0.0 0.0 H -59.9 -40.4 NA NA NA
GLY D:215 D:194 0.0 0.0 H -58.5 -40.9 NA NA NA
GLY E:215 E:194 0.0 0.0 H -58.9 -39.6 NA NA NA
GLY F:215 F:194 0.0 0.0 H -58.3 -39.3 NA NA NA
GLY G:215 G:194 0.0 0.0 H -59.8 -41.1 NA NA NA
GLY H:215 H:194 0.0 0.0 H -60.2 -40.2 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:216 A:194 0.0 0.0 H -59.3 -41.8 0.0 0.0 0.0 FAD
HOH
 8.755
5.285
 H
O
 HM73
O
GLY B:216 B:194 0.0 0.0 H -59.3 -42.6 0.0 0.0 0.0 FAD
HOH
 8.762
5.431
 H
O
 HM72
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 GLY A:216 A:194 0.0 0.0 H -62.6 -41.4 0.0 0.0 0.0 FAD
HOH
 9.594
5.446
 N
O
 C7M
O
GLY B:216 B:194 0.0 0.0 H -59.0 -42.9 0.0 0.0 0.0 FAD
HOH
 9.611
5.379
 N
O
 C7M
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 GLY A:216 A:194 0.0 0.0 H -56.8 -41.7 0.0 0.0 0.0 FAD
HOH
 9.830
5.523
 N
O
 C7M
O
GLY B:216 B:194 0.0 0.0 H -53.1 -45.2 0.0 0.0 0.0 FAD
HOH
 9.717
5.455
 N
O
 C7M
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:216 A:194 0.0 0.0 H -59.6 -42.1 0.0 0.0 0.0 FAD
HOH
 8.734
5.375
 H
O
 HM72
O
GLY B:216 B:194 0.0 0.0 H -60.3 -41.1 0.0 0.0 0.0 FAD
HOH
 8.825
5.383
 H
O
 HM71
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:216 A:194 0.0 0.0 H -53.8 -46.0 0.0 0.0 0.0 FAD
HOH
 8.920
5.316
 H
O
 HM73
O
CYS B:216 B:194 2.0 0.015 H -53.8 -48.2 2.0 0.015 0.0 FAD
HOH
 9.019
5.258
 H
O
 HM73
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:216 A:194 0.0 0.0 H -60.5 -40.7 0.0 0.0 0.0 FAD
HOH
 8.902
5.391
 H
O
 HM73
O
GLY B:216 B:194 0.0 0.0 H -61.5 -41.5 0.0 0.0 0.0 FAD
HOH
 8.847
5.305
 H
O
 HM73
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:216 A:194 0.0 0.0 H -60.3 -38.9 0.0 0.0 0.0 FAD
HOH
 8.841
5.350
 H
O
 HM72
O
GLY B:216 B:194 0.0 0.0 H -61.4 -37.6 0.0 0.0 0.0 FAD
HOH
 9.145
5.057
 H
O
 HM73
O
GLY C:216 C:194 0.0 0.0 H -59.6 -37.2 NA NA NA
GLY D:216 D:194 0.0 0.0 H -59.9 -36.9 NA NA NA
GLY E:216 E:194 0.0 0.0 H -59.1 -39.7 NA NA NA
GLY F:216 F:194 0.0 0.0 H -58.8 -38.0 NA NA NA
GLY G:216 G:194 0.0 0.0 H -59.4 -38.7 NA NA NA
GLY H:216 H:194 0.0 0.0 H -60.8 -37.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 GLY A:229 A:229 0.0 0.0 H -60.7 -41.4