Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107556014 | . | G | A | CCDS5749.1:NM_000108.3:c.748Gga>Aga_NP_000099.2:p.250G>R | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLY | A:236 | A:215 | 29.0 | 0.387 | 75.7 | -168.4 | 29.0 | 0.387 | 0.0 |
HOH |
3.050 |
N |
O |
|||
GLY | B:236 | B:215 | 25.0 | 0.333 | 74.1 | -166.2 | 25.0 | 0.333 | 0.0 |
HOH |
3.303 |
C |
O |
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GLY | C:236 | C:215 | 11.0 | 0.147 | 90.1 | -159.1 | NA | NA | NA | ||||||||||||||
GLY | D:236 | D:215 | 26.0 | 0.347 | 93.2 | -155.3 | NA | NA | NA | ||||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLY | A:215 | A:215 | 21.0 | 0.28 | -77.1 | -137.4 | 21.0 | 0.28 | 0.0 |
HOH |
2.712 |
CA |
O |
|||
GLY | B:215 | B:215 | 22.0 | 0.293 | -76.8 | -129.5 | 22.0 | 0.293 | 0.0 |
HOH |
3.525 |
O |
O |
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GLY | C:215 | C:215 | 19.0 | 0.253 | -63.3 | -133.8 | NA | NA | NA | ||||||||||||||
GLY | D:215 | D:215 | 15.0 | 0.2 | -55.7 | -143.7 | NA | NA | NA | ||||||||||||||
GLY | E:215 | E:215 | 17.0 | 0.227 | 80.3 | 172.6 | NA | NA | NA | ||||||||||||||
GLY | F:215 | F:215 | 24.0 | 0.32 | -72.0 | -145.1 | NA | NA | NA | ||||||||||||||
GLY | G:215 | G:215 | 16.0 | 0.213 | -75.5 | -137.8 | NA | NA | NA | ||||||||||||||
GLY | H:215 | H:215 | 19.0 | 0.253 | -68.0 | -130.4 | NA | NA | NA | ||||||||||||||
GLY | I:215 | I:215 | 29.0 | 0.387 | 96.8 | -141.9 | NA | NA | NA | ||||||||||||||
GLY | J:215 | J:215 | 20.0 | 0.267 | -73.8 | -117.4 | NA | NA | NA | ||||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 21.0 | 0.28 | 80.4 | -165.3 | 21.0 | 0.28 | 0.0 |
SO4 HOH |
7.504 2.121 |
O H |
O4 O |
|||
GLY | B:237 | B:215 | 25.0 | 0.333 | 81.1 | -165.7 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
6.920 1.972 |
O H |
O1 O |
||||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 25.0 | 0.333 | 83.6 | -165.3 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
7.068 2.203 |
O H |
O4 O |
|||
GLY | B:237 | B:215 | 25.0 | 0.333 | 84.6 | -166.5 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
6.978 1.962 |
O H |
O1 O |
||||||||||
1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLY | A:215 | A:215 | 15.0 | 0.2 | 80.4 | -160.3 | 15.0 | 0.2 | 0.0 |
SO4 NAD HOH |
6.679 3.806 2.932 |
O CA N |
O3 O2N O |
|||
GLY | B:215 | B:215 | 21.0 | 0.28 | 82.7 | -163.7 | 21.0 | 0.28 | 0.0 |
SO4 NAD HOH |
6.414 3.307 2.761 |
O CA N |
O1 O5D O |
||||||||||
GLY | C:215 | C:215 | 22.0 | 0.293 | 82.0 | -161.5 | NA | NA | NA | ||||||||||||||
GLY | D:215 | D:215 | 21.0 | 0.28 | 82.0 | -154.0 | NA | NA | NA | ||||||||||||||
GLY | E:215 | E:215 | 24.0 | 0.32 | 80.5 | -159.4 | NA | NA | NA | ||||||||||||||
GLY | F:215 | F:215 | 29.0 | 0.387 | 99.3 | -177.8 | NA | NA | NA | ||||||||||||||
GLY | G:215 | G:215 | 18.0 | 0.24 | 71.2 | -165.3 | NA | NA | NA | ||||||||||||||
GLY | H:215 | H:215 | 21.0 | 0.28 | 77.3 | -156.3 | NA | NA | NA | ||||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLY | A:215 | A:215 | 21.0 | 0.28 | 83.3 | -161.8 | 21.0 | 0.28 | 0.0 |
NAI HOH |
4.393 2.939 |
CA N |
O1A O |
|||
GLY | B:215 | B:215 | 26.0 | 0.347 | 84.9 | -166.0 | 26.0 | 0.347 | 0.0 |
NAI HOH |
4.324 2.863 |
CA N |
O1A O |
||||||||||
GLY | C:215 | C:215 | 27.0 | 0.36 | 81.8 | -166.4 | NA | NA | NA | ||||||||||||||
GLY | D:215 | D:215 | 24.0 | 0.32 | 87.0 | -159.9 | NA | NA | NA | ||||||||||||||
GLY | E:215 | E:215 | 24.0 | 0.32 | 76.4 | -169.7 | NA | NA | NA | ||||||||||||||
GLY | F:215 | F:215 | 25.0 | 0.333 | 85.6 | -166.5 | NA | NA | NA | ||||||||||||||
GLY | G:215 | G:215 | 19.0 | 0.253 | 81.7 | -158.4 | NA | NA | NA | ||||||||||||||
GLY | H:215 | H:215 | 26.0 | 0.347 | 79.6 | -168.3 | NA | NA | NA | ||||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLY | A:215 | A:215 | 25.0 | 0.333 | 69.0 | -170.9 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
7.849 3.043 |
O N |
O2 O |
|||
GLY | B:215 | B:215 | 24.0 | 0.32 | 95.5 | -165.3 | 24.0 | 0.32 | 0.0 |
SO4 HOH |
7.212 3.511 |
O CA |
O4 O |
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GLY | C:215 | C:215 | 23.0 | 0.307 | 79.3 | -167.9 | NA | NA | NA | ||||||||||||||
GLY | D:215 | D:215 | 25.0 | 0.333 | 81.3 | -168.4 | NA | NA | NA | ||||||||||||||
GLY | E:215 | E:215 | 21.0 | 0.28 | 81.4 | -169.8 | NA | NA | NA | ||||||||||||||
GLY | F:215 | F:215 | 24.0 | 0.32 | 87.7 | -168.4 | NA | NA | NA | ||||||||||||||
GLY | G:215 | G:215 | 22.0 | 0.293 | 74.9 | -167.3 | NA | NA | NA | ||||||||||||||
GLY | H:215 | H:215 | 19.0 | 0.253 | 77.5 | -167.6 | NA | NA | NA | ||||||||||||||
GLY | I:215 | I:215 | 23.0 | 0.307 | 88.7 | -171.3 | NA | NA | NA | ||||||||||||||
GLY | J:215 | J:215 | 23.0 | 0.307 | 76.8 | -176.6 | NA | NA | NA | ||||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLY | A:236 | A:215 | 24.0 | 0.32 | 88.3 | -167.0 | 24.0 | 0.32 | 0.0 |
HOH |
2.859 |
HA3 |
O |
|||
GLY | B:236 | B:215 | 21.0 | 0.28 | 86.0 | -171.6 | 21.0 | 0.28 | 0.0 |
HOH |
2.173 |
H |
O |
||||||||||
GLY | C:236 | C:215 | 20.0 | 0.267 | 87.5 | -166.8 | NA | NA | NA | ||||||||||||||
GLY | D:236 | D:215 | 26.0 | 0.347 | 85.8 | -167.4 | NA | NA | NA | ||||||||||||||
GLY | E:236 | E:215 | 24.0 | 0.32 | 86.6 | -163.7 | NA | NA | NA | ||||||||||||||
GLY | F:236 | F:215 | 23.0 | 0.307 | 87.7 | -171.5 | NA | NA | NA | ||||||||||||||
GLY | G:236 | G:215 | 20.0 | 0.267 | 86.3 | -165.4 | NA | NA | NA | ||||||||||||||
GLY | H:236 | H:215 | 23.0 | 0.307 | 85.8 | -168.3 | NA | NA | NA | ||||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 24.0 | 0.32 | 81.4 | -165.8 | 24.0 | 0.32 | 0.0 |
SO4 HOH |
7.076 2.085 |
O H |
O4 O |
|||
GLY | B:237 | B:215 | 25.0 | 0.333 | 82.4 | -164.9 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
7.201 2.151 |
O H |
O1 O |
||||||||||
5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLY | A:237 | A:215 | 17.0 | 0.227 | 83.8 | -161.1 | 17.0 | 0.227 | 0.0 |
HOH |
2.785 |
N |
O |
|||
GLY | B:237 | B:215 | 21.0 | 0.28 | 93.3 | -168.5 | 21.0 | 0.28 | 0.0 |
HOH |
3.017 |
N |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLY | A:237 | A:215 | 24.0 | 0.32 | 85.5 | -162.7 | 24.0 | 0.32 | 0.0 |
SO4 HOH |
7.364 2.803 |
O N |
O4 O |
|||
GLY | B:237 | B:215 | 26.0 | 0.347 | 87.1 | -162.8 | 26.0 | 0.347 | 0.0 |
SO4 SO4 HOH |
3.427 6.802 2.892 |
CA O N |
O3 O2 O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 25.0 | 0.333 | 86.2 | -169.3 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
7.606 2.059 |
O H |
O4 O |
|||
GLY | B:237 | B:215 | 27.0 | 0.36 | 86.8 | -170.1 | 27.0 | 0.36 | 0.0 |
SO4 HOH |
7.097 2.084 |
O H |
O1 O |
||||||||||
6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 20.0 | 0.267 | 86.0 | -167.3 | 20.0 | 0.267 | 0.0 |
SO4 HOH |
7.358 1.903 |
O H |
O4 O |
|||
GLY | B:237 | B:215 | 24.0 | 0.32 | 85.8 | -166.8 | 24.0 | 0.32 | 0.0 |
SO4 HOH |
6.981 1.943 |
O H |
O1 O |
||||||||||
6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 26.0 | 0.347 | 90.2 | -167.1 | 26.0 | 0.347 | 0.0 |
SO4 HOH |
7.529 2.080 |
O H |
O3 O |
|||
GLY | B:237 | B:215 | 28.0 | 0.373 | 91.9 | -167.8 | 28.0 | 0.373 | 0.0 |
SO4 HOH |
6.914 2.158 |
O H |
O1 O |
||||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:237 | A:215 | 20.0 | 0.267 | 88.7 | -169.6 | 20.0 | 0.267 | 0.0 |
SO4 HOH |
7.118 2.138 |
O H |
O4 O |
|||
GLY | B:237 | B:215 | 24.0 | 0.32 | 85.2 | -170.1 | 24.0 | 0.32 | 0.0 |
HOH |
2.237 |
H |
O |
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GLY | C:237 | C:215 | 21.0 | 0.28 | 86.6 | -170.0 | NA | NA | NA | ||||||||||||||
GLY | D:237 | D:215 | 24.0 | 0.32 | 86.8 | -171.3 | NA | NA | NA | ||||||||||||||
GLY | E:237 | E:215 | 21.0 | 0.28 | 89.1 | -168.9 | NA | NA | NA | ||||||||||||||
GLY | F:237 | F:215 | 25.0 | 0.333 | 87.4 | -167.9 | NA | NA | NA | ||||||||||||||
GLY | G:237 | G:215 | 22.0 | 0.293 | 90.4 | -168.1 | NA | NA | NA | ||||||||||||||
GLY | H:237 | H:215 | 21.0 | 0.28 | 88.0 | -168.5 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLY | A:250 | A:250 | 21.0 | 0.28 | 93.5 | -160.9 |