Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107556029 . A C CCDS5749.1:NM_000108.3:c.763Atg>Ctg_NP_000099.2:p.255M>L Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 MET A:241 A:220 59.0 0.319 H -46.4 -53.8 59.0 0.319 0.0 NHE
HOH
 9.669
3.624
 O
CB
 O3
O
MET B:241 B:220 54.0 0.292 H -62.7 -46.7 54.0 0.292 0.0 NHE
HOH
 9.678
3.256
 O
N
 O1
O
MET C:241 C:220 52.0 0.281 H -61.9 -48.8 NA NA NA
MET D:241 D:220 52.0 0.281 H -66.6 -43.6 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 MET A:220 A:220 63.0 0.341 H -74.2 -35.3 63.0 0.341 0.0 HOH
 4.615
 SD
 O
MET B:220 B:220 66.0 0.357 H -49.9 -55.0 66.0 0.357 0.0 HOH
 5.521
 N
 O
MET C:220 C:220 90.0 0.486 H -70.5 -42.2 NA NA NA
MET D:220 D:220 65.0 0.351 H -71.8 -31.3 NA NA NA
MET E:220 E:220 65.0 0.351 H -59.7 -48.5 NA NA NA
MET F:220 F:220 69.0 0.373 H -63.2 -45.7 NA NA NA
MET G:220 G:220 54.0 0.292 H -50.6 -50.6 NA NA NA
MET H:220 H:220 60.0 0.324 H -61.6 -30.9 NA NA NA
MET I:220 I:220 70.0 0.378 H -43.1 -60.5 NA NA NA
MET J:220 J:220 86.0 0.465 H -76.7 -37.8 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 MET A:242 A:220 70.0 0.378 H -64.4 -42.1 70.0 0.378 0.0 SO4
HOH
 4.047
3.004
 SD
H
 O3
O
MET B:242 B:220 72.0 0.389 H -65.8 -41.1 72.0 0.389 0.0 SO4
HOH
 4.062
2.812
 HE1
H
 O2
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:242 A:220 55.0 0.297 H -67.4 -39.4 55.0 0.297 0.0 SO4
HOH
 2.869
2.812
 HE1
H
 O3
O
MET B:242 B:220 67.0 0.362 H -67.8 -39.9 67.0 0.362 0.0 SO4
HOH
 4.495
2.838
 SD
H
 O2
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 MET A:220 A:220 62.0 0.335 H -54.8 -46.3 62.0 0.335 0.0 SO4
HOH
 3.932
4.086
 SD
CE
 O3
O
MET B:220 B:220 56.0 0.303 H -54.4 -48.0 56.0 0.303 0.0 SO4
HOH
 4.186
3.720
 CE
N
 O2
O
MET C:220 C:220 53.0 0.286 H -57.8 -42.6 NA NA NA
MET D:220 D:220 72.0 0.389 H -53.0 -45.0 NA NA NA
MET E:220 E:220 57.0 0.308 H -56.9 -50.0 NA NA NA
MET F:220 F:220 64.0 0.346 H -56.7 -43.5 NA NA NA
MET G:220 G:220 54.0 0.292 H -53.7 -44.6 NA NA NA
MET H:220 H:220 61.0 0.33 H -55.8 -52.5 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 MET A:220 A:220 62.0 0.335 H -59.4 -42.4 62.0 0.335 0.0 NAI
HOH
 9.929
3.216
 CE
N
 O3B
O
MET B:220 B:220 57.0 0.308 H -56.9 -43.6 57.0 0.308 0.0 HOH
 3.552
 N
 O
MET C:220 C:220 54.0 0.292 H -59.2 -42.1 NA NA NA
MET D:220 D:220 45.0 0.243 H -59.2 -43.4 NA NA NA
MET E:220 E:220 60.0 0.324 H -57.2 -47.4 NA NA NA
MET F:220 F:220 61.0 0.33 H -56.1 -45.1 NA NA NA
MET G:220 G:220 63.0 0.341 H -54.2 -45.0 NA NA NA
MET H:220 H:220 53.0 0.286 H -57.7 -47.0 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 MET A:220 A:220 59.0 0.319 H -58.4 -49.8 59.0 0.319 0.0 SO4
HOH
 4.020
3.452
 CE
N
 O3
O
MET B:220 B:220 61.0 0.33 H -67.7 -39.9 61.0 0.33 0.0 SO4
HOH
 4.276
5.740
 SD
O
 O4
O
MET C:220 C:220 63.0 0.341 H -61.4 -43.3 NA NA NA
MET D:220 D:220 52.0 0.281 H -56.8 -45.9 NA NA NA
MET E:220 E:220 60.0 0.324 H -63.0 -40.7 NA NA NA
MET F:220 F:220 57.0 0.308 H -64.6 -39.0 NA NA NA
MET G:220 G:220 58.0 0.314 H -56.7 -44.4 NA NA NA
MET H:220 H:220 56.0 0.303 H -60.7 -43.4 NA NA NA
MET I:220 I:220 61.0 0.33 H -58.9 -48.9 NA NA NA
MET J:220 J:220 54.0 0.292 H -53.8 -47.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 MET A:241 A:220 61.0 0.33 H -68.1 -42.2 61.0 0.33 0.0 HOH
 2.541
 H
 O
MET B:241 B:220 56.0 0.303 H -66.4 -42.1 56.0 0.303 0.0 HOH
 2.750
 H
 O
MET C:241 C:220 53.0 0.286 H -66.0 -42.3 NA NA NA
MET D:241 D:220 48.0 0.259 H -67.7 -43.0 NA NA NA
MET E:241 E:220 59.0 0.319 H -66.3 -42.0 NA NA NA
MET F:241 F:220 60.0 0.324 H -67.2 -43.4 NA NA NA
MET G:241 G:220 51.0 0.276 H -66.5 -42.9 NA NA NA
MET H:241 H:220 46.0 0.249 H -66.5 -42.6 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:242 A:220 54.0 0.292 H -66.1 -43.3 54.0 0.292 0.0 SO4
HOH
 4.256
2.863
 HE1
H
 O3
O
MET B:242 B:220 65.0 0.351 H -67.6 -40.9 65.0 0.351 0.0 SO4
HOH
 4.435
2.863
 HE1
H
 O2
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 MET A:242 A:220 48.0 0.259 H -67.2 -45.7 48.0 0.259 0.0 HOH
 3.142
 CE
 O
MET B:242 B:220 69.0 0.373 H -70.1 -41.0 69.0 0.373 0.0 HOH
 3.286
 N
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 MET A:242 A:220 49.0 0.265 H -60.3 -43.7 49.0 0.265 0.0 SO4
HOH
 4.134
3.403
 SD
N
 O3
O
MET B:242 B:220 62.0 0.335 H -64.7 -37.9 62.0 0.335 0.0 SO4
HOH
 4.310
2.693
 SD
SD
 O1
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:242 A:220 73.0 0.395 H -70.5 -38.3 73.0 0.395 0.0 HOH
 5.929
 N
 O
MET B:242 B:220 69.0 0.373 H -67.3 -40.9 69.0 0.373 0.0 HOH
 5.980
 N
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:242 A:220 54.0 0.292 H -66.4 -42.1 54.0 0.292 0.0 HOH
 5.876
 N
 O
MET B:242 B:220 79.0 0.427 H -69.8 -37.7 79.0 0.427 0.0 HOH
 5.986
 N
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:242 A:220 46.0 0.249 H -66.5 -41.9 46.0 0.249 0.0 SO4
HOH
 3.853
2.889
 HE3
H
 O3
O
MET B:242 B:220 55.0 0.297 H -67.3 -40.3 55.0 0.297 0.0 SO4
HOH
 4.458
2.928
 HE1
H
 O1
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:242 A:220 73.0 0.395 H -65.5 -42.7 73.0 0.395 0.0 SO4
HOH
 2.467
2.910
 HE1
H
 O4
O
MET B:242 B:220 75.0 0.405 H -68.3 -44.1 75.0 0.405 0.0 HOH
 2.952
 H
 O
MET C:242 C:220 80.0 0.432 H -66.4 -44.2 NA NA NA
MET D:242 D:220 76.0 0.411 H -68.3 -43.1 NA NA NA
MET E:242 E:220 75.0 0.405 H -66.8 -42.6 NA NA NA
MET F:242 F:220 53.0 0.286 H -68.4 -43.4 NA NA NA
MET G:242 G:220 66.0 0.357 H -67.4 -42.6 NA NA NA
MET H:242 H:220 54.0 0.292 H -68.9 -43.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 MET A:255 A:255 61.0 0.33 H -67.8 -30.0