Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107556053 | . | C | A | CCDS5749.1:NM_000108.3:c.787Cgc>Agc_NP_000099.2:p.263R>S | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | ARG | A:249 | A:228 | 150.0 | 0.667 | H | -58.2 | -46.0 | 150.0 | 0.667 | 0.0 |
NHE HOH |
4.342 3.228 |
NH1 NH1 |
O3 O |
||
ARG | B:249 | B:228 | 154.0 | 0.684 | H | -45.5 | -48.9 | 154.0 | 0.684 | 0.0 |
NHE HOH |
5.198 6.575 |
CD N |
O3 O |
|||||||||
ARG | C:249 | C:228 | 156.0 | 0.693 | H | -52.5 | -51.6 | NA | NA | NA | |||||||||||||
ARG | D:249 | D:228 | 139.0 | 0.618 | H | -45.0 | -55.4 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | ARG | A:228 | A:228 | 159.0 | 0.707 | H | -50.8 | -42.4 | 159.0 | 0.707 | 0.0 |
HOH |
5.973 |
N |
O |
||
ARG | B:228 | B:228 | 128.0 | 0.569 | H | -36.1 | -40.8 | 128.0 | 0.569 | 0.0 |
HOH |
3.143 |
CG |
O |
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ARG | C:228 | C:228 | 114.0 | 0.507 | H | -58.4 | -47.1 | NA | NA | NA | |||||||||||||
ARG | D:228 | D:228 | 128.0 | 0.569 | H | -46.6 | -41.8 | NA | NA | NA | |||||||||||||
ARG | E:228 | E:228 | 152.0 | 0.676 | H | -68.0 | -36.9 | NA | NA | NA | |||||||||||||
ARG | F:228 | F:228 | 111.0 | 0.493 | H | -68.2 | -28.0 | NA | NA | NA | |||||||||||||
ARG | G:228 | G:228 | 115.0 | 0.511 | H | -68.4 | -32.7 | NA | NA | NA | |||||||||||||
ARG | H:228 | H:228 | 124.0 | 0.551 | H | -64.7 | -33.5 | NA | NA | NA | |||||||||||||
ARG | I:228 | I:228 | 105.0 | 0.467 | H | -70.7 | -36.2 | NA | NA | NA | |||||||||||||
ARG | J:228 | J:228 | 108.0 | 0.48 | H | -61.0 | -46.8 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 159.0 | 0.707 | H | -60.6 | -39.2 | 159.0 | 0.707 | 0.0 |
HOH |
2.939 |
HD3 |
O |
||
ARG | B:250 | B:228 | 163.0 | 0.724 | H | -62.6 | -39.0 | 163.0 | 0.724 | 0.0 |
HOH |
2.750 |
HB3 |
O |
|||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 120.0 | 0.533 | H | -58.0 | -40.0 | 120.0 | 0.533 | 0.0 |
HOH |
2.076 |
HH21 |
O |
||
ARG | B:250 | B:228 | 103.0 | 0.458 | H | -57.8 | -41.6 | 103.0 | 0.458 | 0.0 |
HOH |
2.424 |
HH22 |
O |
|||||||||
1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | ARG | A:228 | A:228 | 152.0 | 0.676 | H | -53.0 | -48.3 | 152.0 | 0.676 | 0.0 |
HOH |
6.483 |
N |
O |
||
ARG | B:228 | B:228 | 117.0 | 0.52 | H | -58.8 | -42.6 | 117.0 | 0.52 | 0.0 |
HOH |
3.021 |
O |
O |
|||||||||
ARG | C:228 | C:228 | 116.0 | 0.516 | H | -59.7 | -37.4 | NA | NA | NA | |||||||||||||
ARG | D:228 | D:228 | 126.0 | 0.56 | H | -55.8 | -41.0 | NA | NA | NA | |||||||||||||
ARG | E:228 | E:228 | 113.0 | 0.502 | H | -53.5 | -55.4 | NA | NA | NA | |||||||||||||
ARG | F:228 | F:228 | 142.0 | 0.631 | H | -65.0 | -42.7 | NA | NA | NA | |||||||||||||
ARG | G:228 | G:228 | 156.0 | 0.693 | H | -62.1 | -41.8 | NA | NA | NA | |||||||||||||
ARG | H:228 | H:228 | 146.0 | 0.649 | H | -57.6 | -50.5 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | ARG | A:228 | A:228 | 133.0 | 0.591 | H | -61.9 | -38.5 | 133.0 | 0.591 | 0.0 |
HOH |
4.755 |
O |
O |
||
ARG | B:228 | B:228 | 109.0 | 0.484 | H | -64.8 | -37.9 | 109.0 | 0.484 | 0.0 |
HOH |
2.838 |
O |
O |
|||||||||
ARG | C:228 | C:228 | 126.0 | 0.56 | H | -58.5 | -45.2 | NA | NA | NA | |||||||||||||
ARG | D:228 | D:228 | 150.0 | 0.667 | H | -53.7 | -47.1 | NA | NA | NA | |||||||||||||
ARG | E:228 | E:228 | 140.0 | 0.622 | H | -59.6 | -42.9 | NA | NA | NA | |||||||||||||
ARG | F:228 | F:228 | 141.0 | 0.627 | H | -63.7 | -41.7 | NA | NA | NA | |||||||||||||
ARG | G:228 | G:228 | 192.0 | 0.853 | H | -64.2 | -39.5 | NA | NA | NA | |||||||||||||
ARG | H:228 | H:228 | 124.0 | 0.551 | H | -55.2 | -45.6 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | ARG | A:228 | A:228 | 117.0 | 0.52 | H | -58.1 | -42.3 | 117.0 | 0.52 | 0.0 |
HOH |
2.798 |
O |
O |
||
ARG | B:228 | B:228 | 114.0 | 0.507 | H | -56.7 | -39.3 | 114.0 | 0.507 | 0.0 |
HOH |
3.003 |
O |
O |
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ARG | C:228 | C:228 | 131.0 | 0.582 | H | -62.1 | -44.2 | NA | NA | NA | |||||||||||||
ARG | D:228 | D:228 | 121.0 | 0.538 | H | -61.6 | -43.3 | NA | NA | NA | |||||||||||||
ARG | E:228 | E:228 | 144.0 | 0.64 | H | -58.1 | -48.1 | NA | NA | NA | |||||||||||||
ARG | F:228 | F:228 | 130.0 | 0.578 | H | -60.7 | -38.5 | NA | NA | NA | |||||||||||||
ARG | G:228 | G:228 | 129.0 | 0.573 | H | -57.8 | -41.8 | NA | NA | NA | |||||||||||||
ARG | H:228 | H:228 | 113.0 | 0.502 | H | -60.2 | -39.0 | NA | NA | NA | |||||||||||||
ARG | I:228 | I:228 | 135.0 | 0.6 | H | -64.0 | -39.0 | NA | NA | NA | |||||||||||||
ARG | J:228 | J:228 | 144.0 | 0.64 | H | -58.0 | -44.1 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | ARG | A:249 | A:228 | 106.0 | 0.471 | H | -55.1 | -48.4 | 106.0 | 0.471 | 0.0 |
HOH |
2.507 |
HH22 |
O |
||
ARG | B:249 | B:228 | 112.0 | 0.498 | H | -57.9 | -44.4 | 112.0 | 0.498 | 0.0 |
HOH |
2.104 |
HE |
O |
|||||||||
ARG | C:249 | C:228 | 106.0 | 0.471 | H | -56.8 | -45.5 | NA | NA | NA | |||||||||||||
ARG | D:249 | D:228 | 127.0 | 0.564 | H | -58.4 | -44.1 | NA | NA | NA | |||||||||||||
ARG | E:249 | E:228 | 126.0 | 0.56 | H | -60.9 | -41.4 | NA | NA | NA | |||||||||||||
ARG | F:249 | F:228 | 124.0 | 0.551 | H | -58.6 | -46.0 | NA | NA | NA | |||||||||||||
ARG | G:249 | G:228 | 164.0 | 0.729 | H | -60.5 | -45.4 | NA | NA | NA | |||||||||||||
ARG | H:249 | H:228 | 142.0 | 0.631 | H | -58.6 | -44.2 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 155.0 | 0.689 | H | -64.2 | -34.5 | 155.0 | 0.689 | 0.0 |
HOH |
2.337 |
HH12 |
O |
||
ARG | B:250 | B:228 | 99.0 | 0.44 | H | -60.9 | -40.2 | 99.0 | 0.44 | 0.0 |
HOH |
2.541 |
HH12 |
O |
|||||||||
5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | ARG | A:250 | A:228 | 167.0 | 0.742 | H | -56.0 | -42.6 | 167.0 | 0.742 | 0.0 |
HOH |
3.247 |
CD |
O |
||
ARG | B:250 | B:228 | 118.0 | 0.524 | H | -59.2 | -42.9 | 118.0 | 0.524 | 0.0 |
HOH |
3.631 |
CB |
O |
|||||||||
6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | ARG | A:250 | A:228 | 132.0 | 0.587 | H | -59.9 | -40.7 | 132.0 | 0.587 | 0.0 |
HOH |
2.746 |
O |
O |
||
ARG | B:250 | B:228 | 150.0 | 0.667 | H | -54.6 | -44.9 | 150.0 | 0.667 | 0.0 |
HOH |
3.556 |
CB |
O |
|||||||||
6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 195.0 | 0.867 | H | -62.7 | -39.8 | 195.0 | 0.867 | 0.0 |
HOH |
2.504 |
HG3 |
O |
||
ARG | B:250 | B:228 | 114.0 | 0.507 | H | -63.2 | -38.8 | 114.0 | 0.507 | 0.0 |
HOH |
4.725 |
O |
O |
|||||||||
6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 109.0 | 0.484 | H | -60.4 | -42.2 | 109.0 | 0.484 | 0.0 |
HOH |
9.835 |
O |
O |
||
ARG | B:250 | B:228 | 95.0 | 0.422 | H | -61.3 | -41.3 | 95.0 | 0.422 | 0.0 |
HOH |
5.290 |
O |
O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 151.0 | 0.671 | H | -58.2 | -41.8 | 151.0 | 0.671 | 0.0 |
HOH |
2.500 |
HG2 |
O |
||
ARG | B:250 | B:228 | 128.0 | 0.569 | H | -60.9 | -41.3 | 128.0 | 0.569 | 0.0 |
HOH |
2.367 |
HG3 |
O |
|||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:250 | A:228 | 170.0 | 0.756 | H | -63.9 | -41.4 | 170.0 | 0.756 | 0.0 |
HOH |
6.246 |
H |
O |
||
ARG | B:250 | B:228 | 178.0 | 0.791 | H | -62.2 | -39.0 | 178.0 | 0.791 | 0.0 |
HOH |
6.651 |
HH22 |
O |
|||||||||
ARG | C:250 | C:228 | 97.0 | 0.431 | H | -62.3 | -44.1 | NA | NA | NA | |||||||||||||
ARG | D:250 | D:228 | 127.0 | 0.564 | H | -64.4 | -37.9 | NA | NA | NA | |||||||||||||
ARG | E:250 | E:228 | 185.0 | 0.822 | H | -67.4 | -37.2 | NA | NA | NA | |||||||||||||
ARG | F:250 | F:228 | 162.0 | 0.72 | H | -64.6 | -36.2 | NA | NA | NA | |||||||||||||
ARG | G:250 | G:228 | 151.0 | 0.671 | H | -64.3 | -38.6 | NA | NA | NA | |||||||||||||
ARG | H:250 | H:228 | 165.0 | 0.733 | H | -63.4 | -40.6 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | ARG | A:263 | A:263 | 121.0 | 0.538 | H | -60.4 | -39.8 |