Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107556068 | . | C | A | CCDS5749.1:NM_000108.3:c.802Cag>Aag_NP_000099.2:p.268Q>K | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLN | A:254 | A:233 | 55.0 | 0.306 | T | -74.7 | -10.7 | 55.0 | 0.306 | 0.0 |
HOH |
2.857 |
OE1 |
O |
||
GLN | B:254 | B:233 | 59.0 | 0.328 | H | -81.7 | -16.7 | 59.0 | 0.328 | 0.0 |
HOH |
2.708 |
OE1 |
O |
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GLN | C:254 | C:233 | 59.0 | 0.328 | H | -70.3 | -18.1 | NA | NA | NA | |||||||||||||
GLN | D:254 | D:233 | 55.0 | 0.306 | H | -79.2 | -16.8 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLN | A:233 | A:233 | 59.0 | 0.328 | H | -64.2 | -27.0 | 59.0 | 0.328 | 0.0 |
HOH |
3.288 |
NE2 |
O |
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GLN | B:233 | B:233 | 50.0 | 0.278 | H | -73.3 | -22.1 | 50.0 | 0.278 | 0.0 |
HOH |
2.713 |
NE2 |
O |
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GLN | C:233 | C:233 | 59.0 | 0.328 | H | -67.5 | -16.6 | NA | NA | NA | |||||||||||||
GLN | D:233 | D:233 | 57.0 | 0.317 | T | -80.1 | 9.2 | NA | NA | NA | |||||||||||||
GLN | E:233 | E:233 | 58.0 | 0.322 | T | -93.8 | 1.2 | NA | NA | NA | |||||||||||||
GLN | F:233 | F:233 | 54.0 | 0.3 | H | -80.3 | -9.9 | NA | NA | NA | |||||||||||||
GLN | G:233 | G:233 | 49.0 | 0.272 | T | -89.7 | -11.1 | NA | NA | NA | |||||||||||||
GLN | H:233 | H:233 | 47.0 | 0.261 | T | -89.0 | -17.2 | NA | NA | NA | |||||||||||||
GLN | I:233 | I:233 | 57.0 | 0.317 | H | -69.2 | -32.4 | NA | NA | NA | |||||||||||||
GLN | J:233 | J:233 | 48.0 | 0.267 | H | -86.2 | -18.0 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 55.0 | 0.306 | H | -70.5 | -21.2 | 55.0 | 0.306 | 0.0 |
SO4 HOH |
5.227 2.270 |
HA HE21 |
O1 O |
||
GLN | B:255 | B:233 | 54.0 | 0.3 | H | -70.1 | -19.6 | 54.0 | 0.3 | 0.0 |
SO4 HOH |
5.602 1.986 |
HA HE21 |
O3 O |
|||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 49.0 | 0.272 | H | -69.0 | -24.2 | 49.0 | 0.272 | 0.0 |
SO4 HOH |
5.224 2.416 |
HA HE21 |
O2 O |
||
GLN | B:255 | B:233 | 51.0 | 0.283 | H | -69.0 | -21.5 | 51.0 | 0.283 | 0.0 |
SO4 HOH |
5.687 2.080 |
HA HE21 |
O3 O |
|||||||||
1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLN | A:233 | A:233 | 51.0 | 0.283 | T | -98.8 | -16.4 | 51.0 | 0.283 | 0.0 |
SO4 HOH |
6.734 2.699 |
CA OE1 |
O1 O |
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GLN | B:233 | B:233 | 47.0 | 0.261 | T | -93.9 | -17.2 | 47.0 | 0.261 | 0.0 |
SO4 HOH |
6.076 2.834 |
O OE1 |
O4 O |
|||||||||
GLN | C:233 | C:233 | 49.0 | 0.272 | T | -90.6 | -18.0 | NA | NA | NA | |||||||||||||
GLN | D:233 | D:233 | 52.0 | 0.289 | T | -98.7 | -18.7 | NA | NA | NA | |||||||||||||
GLN | E:233 | E:233 | 45.0 | 0.25 | H | -77.3 | -17.5 | NA | NA | NA | |||||||||||||
GLN | F:233 | F:233 | 47.0 | 0.261 | H | -77.0 | -17.6 | NA | NA | NA | |||||||||||||
GLN | G:233 | G:233 | 49.0 | 0.272 | H | -74.8 | -23.8 | NA | NA | NA | |||||||||||||
GLN | H:233 | H:233 | 35.0 | 0.194 | H | -79.1 | -13.7 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLN | A:233 | A:233 | 46.0 | 0.256 | T | -81.6 | -12.5 | 46.0 | 0.256 | 0.0 |
SO4 HOH |
6.308 2.684 |
O OE1 |
O1 O |
||
GLN | B:233 | B:233 | 48.0 | 0.267 | H | -81.5 | -14.2 | 48.0 | 0.267 | 0.0 |
SO4 HOH |
6.375 2.692 |
O OE1 |
O4 O |
|||||||||
GLN | C:233 | C:233 | 48.0 | 0.267 | H | -77.9 | -14.6 | NA | NA | NA | |||||||||||||
GLN | D:233 | D:233 | 49.0 | 0.272 | H | -81.4 | -9.0 | NA | NA | NA | |||||||||||||
GLN | E:233 | E:233 | 48.0 | 0.267 | H | -77.9 | -17.5 | NA | NA | NA | |||||||||||||
GLN | F:233 | F:233 | 51.0 | 0.283 | H | -80.5 | -15.8 | NA | NA | NA | |||||||||||||
GLN | G:233 | G:233 | 47.0 | 0.261 | H | -80.9 | -17.4 | NA | NA | NA | |||||||||||||
GLN | H:233 | H:233 | 46.0 | 0.256 | H | -80.4 | -11.4 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLN | A:233 | A:233 | 54.0 | 0.3 | H | -77.6 | -14.2 | 54.0 | 0.3 | 0.0 |
SO4 HOH |
6.431 2.704 |
O O |
O4 O |
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GLN | B:233 | B:233 | 58.0 | 0.322 | H | -72.4 | -16.2 | 58.0 | 0.322 | 0.0 |
SO4 HOH |
6.195 2.715 |
O OE1 |
O3 O |
|||||||||
GLN | C:233 | C:233 | 58.0 | 0.322 | H | -77.8 | -18.0 | NA | NA | NA | |||||||||||||
GLN | D:233 | D:233 | 54.0 | 0.3 | H | -79.4 | -13.2 | NA | NA | NA | |||||||||||||
GLN | E:233 | E:233 | 57.0 | 0.317 | H | -78.8 | -15.4 | NA | NA | NA | |||||||||||||
GLN | F:233 | F:233 | 58.0 | 0.322 | H | -79.9 | -14.6 | NA | NA | NA | |||||||||||||
GLN | G:233 | G:233 | 58.0 | 0.322 | H | -74.3 | -19.6 | NA | NA | NA | |||||||||||||
GLN | H:233 | H:233 | 57.0 | 0.317 | H | -73.3 | -19.8 | NA | NA | NA | |||||||||||||
GLN | I:233 | I:233 | 48.0 | 0.267 | H | -87.3 | -11.3 | NA | NA | NA | |||||||||||||
GLN | J:233 | J:233 | 58.0 | 0.322 | H | -75.6 | -19.1 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLN | A:254 | A:233 | 51.0 | 0.283 | H | -70.2 | -21.0 | 51.0 | 0.283 | 0.0 |
HOH |
2.116 |
HE21 |
O |
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GLN | B:254 | B:233 | 56.0 | 0.311 | H | -70.2 | -20.8 | 56.0 | 0.311 | 0.0 |
HOH |
2.781 |
OE1 |
O |
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GLN | C:254 | C:233 | 52.0 | 0.289 | H | -70.8 | -21.7 | NA | NA | NA | |||||||||||||
GLN | D:254 | D:233 | 47.0 | 0.261 | H | -68.1 | -18.9 | NA | NA | NA | |||||||||||||
GLN | E:254 | E:233 | 50.0 | 0.278 | H | -69.3 | -17.1 | NA | NA | NA | |||||||||||||
GLN | F:254 | F:233 | 45.0 | 0.25 | H | -71.2 | -21.1 | NA | NA | NA | |||||||||||||
GLN | G:254 | G:233 | 43.0 | 0.239 | H | -69.8 | -19.9 | NA | NA | NA | |||||||||||||
GLN | H:254 | H:233 | 47.0 | 0.261 | H | -72.0 | -21.3 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 47.0 | 0.261 | H | -72.5 | -19.1 | 47.0 | 0.261 | 0.0 |
SO4 HOH |
5.236 2.212 |
HA HE21 |
O1 O |
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GLN | B:255 | B:233 | 51.0 | 0.283 | H | -72.3 | -17.7 | 51.0 | 0.283 | 0.0 |
SO4 HOH |
5.567 2.165 |
HA HE21 |
O3 O |
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5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLN | A:255 | A:233 | 53.0 | 0.294 | H | -70.5 | -15.0 | 53.0 | 0.294 | 0.0 |
HOH |
2.759 |
OE1 |
O |
||
GLN | B:255 | B:233 | 59.0 | 0.328 | T | -77.3 | -13.2 | 59.0 | 0.328 | 0.0 |
HOH |
2.903 |
OE1 |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLN | A:255 | A:233 | 47.0 | 0.261 | H | -72.0 | -17.9 | 47.0 | 0.261 | 0.0 |
SO4 HOH |
6.105 2.802 |
O OE1 |
O2 O |
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GLN | B:255 | B:233 | 55.0 | 0.306 | H | -71.8 | -23.8 | 55.0 | 0.306 | 0.0 |
SO4 HOH |
6.368 2.867 |
O OE1 |
O4 O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 51.0 | 0.283 | H | -70.2 | -22.6 | 51.0 | 0.283 | 0.0 |
SO4 HOH |
5.424 2.142 |
HA HE21 |
O1 O |
||
GLN | B:255 | B:233 | 52.0 | 0.289 | H | -69.6 | -22.5 | 52.0 | 0.289 | 0.0 |
SO4 HOH |
5.829 2.107 |
HA HE21 |
O3 O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 49.0 | 0.272 | H | -75.3 | -18.8 | 49.0 | 0.272 | 0.0 |
SO4 HOH |
5.647 2.662 |
HA OE1 |
O4 O |
||
GLN | B:255 | B:233 | 49.0 | 0.272 | H | -73.9 | -17.1 | 49.0 | 0.272 | 0.0 |
SO4 HOH |
5.868 2.152 |
HA HE21 |
O3 O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 52.0 | 0.289 | H | -70.8 | -21.9 | 52.0 | 0.289 | 0.0 |
SO4 HOH |
5.343 2.017 |
HA HE21 |
O2 O |
||
GLN | B:255 | B:233 | 54.0 | 0.3 | H | -71.9 | -21.3 | 54.0 | 0.3 | 0.0 |
SO4 HOH |
5.592 2.053 |
HA HE21 |
O3 O |
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6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLN | A:255 | A:233 | 53.0 | 0.294 | H | -76.7 | -13.7 | 53.0 | 0.294 | 0.0 |
SO4 HOH |
6.093 2.660 |
HA OE1 |
O2 O |
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GLN | B:255 | B:233 | 53.0 | 0.294 | H | -80.0 | -15.9 | 53.0 | 0.294 | 0.0 |
SO4 HOH |
6.953 2.901 |
HA OE1 |
O4 O |
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GLN | C:255 | C:233 | 54.0 | 0.3 | H | -76.2 | -15.2 | NA | NA | NA | |||||||||||||
GLN | D:255 | D:233 | 55.0 | 0.306 | H | -76.7 | -15.8 | NA | NA | NA | |||||||||||||
GLN | E:255 | E:233 | 54.0 | 0.3 | H | -78.2 | -15.0 | NA | NA | NA | |||||||||||||
GLN | F:255 | F:233 | 53.0 | 0.294 | H | -77.7 | -15.6 | NA | NA | NA | |||||||||||||
GLN | G:255 | G:233 | 50.0 | 0.278 | H | -76.7 | -14.9 | NA | NA | NA | |||||||||||||
GLN | H:255 | H:233 | 53.0 | 0.294 | H | -77.6 | -15.5 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLN | A:268 | A:268 | 46.0 | 0.256 | H | -75.0 | -13.2 |