Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107556092 . A C CCDS5749.1:NM_000108.3:c.826Aca>Cca_NP_000099.2:p.276T>P Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 THR A:262 A:241 19.0 0.136 E -126.5 141.0 19.0 0.136 0.0 HOH
 4.879
 OG1
 O
THR B:262 B:241 19.0 0.136 -129.1 136.8 19.0 0.136 0.0
THR C:262 C:241 18.0 0.129 E -138.9 131.3 NA NA NA
THR D:262 D:241 16.0 0.114 -118.8 135.9 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 THR A:241 A:241 18.0 0.129 E -146.7 135.7 18.0 0.129 0.0 HOH
 2.772
 OG1
 O
THR B:241 B:241 13.0 0.093 E -121.3 155.1 13.0 0.093 0.0 HOH
 7.559
 OG1
 O
THR C:241 C:241 13.0 0.093 E -130.8 134.2 NA NA NA
THR D:241 D:241 19.0 0.136 E -134.3 161.6 NA NA NA
THR E:241 E:241 17.0 0.121 E -123.7 164.9 NA NA NA
THR F:241 F:241 15.0 0.107 E -138.2 139.0 NA NA NA
THR G:241 G:241 16.0 0.114 E -128.8 116.0 NA NA NA
THR H:241 H:241 15.0 0.107 B -132.2 158.3 NA NA NA
THR I:241 I:241 16.0 0.114 E -131.5 150.7 NA NA NA
THR J:241 J:241 17.0 0.121 E -134.7 150.9 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 THR A:263 A:241 18.0 0.129 E -133.4 133.2 18.0 0.129 0.0 SO4
HOH
 8.324
3.364
 H
O
 O2
O
THR B:263 B:241 17.0 0.121 E -134.9 134.4 17.0 0.121 0.0 SO4
HOH
 8.382
3.024
 H
O
 O3
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:263 A:241 18.0 0.129 E -131.0 132.1 18.0 0.129 0.0 SO4
HOH
 8.429
5.302
 H
HG1
 O2
O
THR B:263 B:241 15.0 0.107 E -132.2 132.2 15.0 0.107 0.0 SO4
HOH
 8.352
4.476
 H
O
 O4
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 THR A:241 A:241 22.0 0.157 E -135.1 132.6 22.0 0.157 0.0 SO4
NAD
HOH
 9.097
3.355
3.840
 N
O
OG1
 O4
C2A
O
THR B:241 B:241 17.0 0.121 E -126.0 127.0 17.0 0.121 0.0 SO4
NAD
HOH
 8.799
3.225
4.180
 N
O
CG2
 O4
C2A
O
THR C:241 C:241 13.0 0.093 E -129.3 135.0 NA NA NA
THR D:241 D:241 22.0 0.157 B -139.0 136.9 NA NA NA
THR E:241 E:241 9.0 0.064 E -133.2 139.1 NA NA NA
THR F:241 F:241 13.0 0.093 E -138.4 127.9 NA NA NA
THR G:241 G:241 19.0 0.136 E -129.7 126.4 NA NA NA
THR H:241 H:241 13.0 0.093 E -123.7 129.8 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 THR A:241 A:241 21.0 0.15 E -131.8 137.6 21.0 0.15 0.0 NAI
HOH
 3.892
9.739
 O
N
 C2A
O
THR B:241 B:241 15.0 0.107 E -127.6 135.5 15.0 0.107 0.0 NAI
HOH
 4.448
4.276
 O
CG2
 C2A
O
THR C:241 C:241 13.0 0.093 E -125.8 141.5 NA NA NA
THR D:241 D:241 19.0 0.136 E -133.3 142.3 NA NA NA
THR E:241 E:241 12.0 0.086 E -147.9 139.2 NA NA NA
THR F:241 F:241 17.0 0.121 E -134.9 133.6 NA NA NA
THR G:241 G:241 19.0 0.136 E -125.9 128.4 NA NA NA
THR H:241 H:241 13.0 0.093 E -133.2 135.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 THR A:241 A:241 18.0 0.129 E -138.1 139.9 18.0 0.129 0.0 SO4
HOH
 9.117
3.284
 N
O
 O2
O
THR B:241 B:241 10.0 0.071 E -140.3 139.1 10.0 0.071 0.0 SO4
HOH
 8.799
3.582
 N
O
 O3
O
THR C:241 C:241 19.0 0.136 E -129.5 147.2 NA NA NA
THR D:241 D:241 17.0 0.121 E -128.8 139.0 NA NA NA
THR E:241 E:241 18.0 0.129 E -131.3 141.4 NA NA NA
THR F:241 F:241 20.0 0.143 E -130.3 137.8 NA NA NA
THR G:241 G:241 19.0 0.136 E -132.2 140.4 NA NA NA
THR H:241 H:241 17.0 0.121 E -136.8 145.0 NA NA NA
THR I:241 I:241 12.0 0.086 E -129.6 137.5 NA NA NA
THR J:241 J:241 16.0 0.114 E -136.9 137.2 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 THR A:262 A:241 15.0 0.107 E -127.2 135.6 15.0 0.107 0.0 HOH
 9.112
 HG21
 O
THR B:262 B:241 17.0 0.121 E -126.4 134.8 17.0 0.121 0.0 HOH
 7.742
 HG1
 O
THR C:262 C:241 19.0 0.136 E -127.2 133.3 NA NA NA
THR D:262 D:241 11.0 0.079 E -125.4 130.7 NA NA NA
THR E:262 E:241 20.0 0.143 E -127.0 134.3 NA NA NA
THR F:262 F:241 24.0 0.171 E -131.9 139.1 NA NA NA
THR G:262 G:241 16.0 0.114 E -125.5 135.0 NA NA NA
THR H:262 H:241 15.0 0.107 E -127.2 135.0 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:263 A:241 18.0 0.129 E -133.2 131.3 18.0 0.129 0.0 SO4
HOH
 8.516
3.512
 H
O
 O2
O
THR B:263 B:241 17.0 0.121 E -134.0 131.3 17.0 0.121 0.0 SO4
HOH
 8.432
4.878
 H
O
 O3
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 THR A:263 A:241 18.0 0.129 E -145.4 127.6 18.0 0.129 0.0 HOH
 4.725
 O
 O
THR B:263 B:241 18.0 0.129 E -139.2 135.2 18.0 0.129 0.0 HOH
 3.038
 O
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 THR A:263 A:241 18.0 0.129 E -142.4 132.9 18.0 0.129 0.0 SO4
HOH
 8.629
2.996
 N
OG1
 O1
O
THR B:263 B:241 17.0 0.121 E -131.0 136.5 17.0 0.121 0.0 SO4
HOH
 8.887
3.078
 N
OG1
 O4
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:263 A:241 19.0 0.136 E -134.7 134.7 19.0 0.136 0.0 SO4
HOH
 8.656
3.022
 H
OG1
 O1
O
THR B:263 B:241 18.0 0.129 E -135.4 134.9 18.0 0.129 0.0 SO4
HOH
 8.590
2.900
 H
OG1
 O4
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:263 A:241 16.0 0.114 E -134.5 131.3 16.0 0.114 0.0 SO4
HOH
 8.417
3.170
 H
O
 O2
O
THR B:263 B:241 13.0 0.093 E -133.7 134.2 13.0 0.093 0.0 SO4
HOH
 8.521
2.965
 H
O
 O4
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:263 A:241 19.0 0.136 E -136.1 132.4 19.0 0.136 0.0 SO4
HOH
 8.790
3.008
 H
O
 O2
O
THR B:263 B:241 16.0 0.114 E -137.0 133.0 16.0 0.114 0.0 SO4
HOH
 8.509
2.755
 H
OG1
 O3
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:263 A:241 20.0 0.143 E -135.6 136.1 20.0 0.143 0.0 SO4
HOH
 8.262
5.455
 H
HG1
 O2
O
THR B:263 B:241 20.0 0.143 E -137.1 141.6 20.0 0.143 0.0
THR C:263 C:241 21.0 0.15 E -134.8 135.9 NA NA NA
THR D:263 D:241 18.0 0.129 E -137.1 140.4 NA NA NA
THR E:263 E:241 11.0 0.079 E -137.2 140.4 NA NA NA
THR F:263 F:241 17.0 0.121 E -133.6 140.1 NA NA NA
THR G:263 G:241 17.0 0.121 E -135.4 138.3 NA NA NA
THR H:263 H:241 17.0 0.121 E -138.0 140.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 THR A:276 A:276 19.0 0.136 E -132.4 126.9