Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107556095 | . | A | C | CCDS5749.1:NM_000108.3:c.829Aag>Cag_NP_000099.2:p.277K>Q | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | LYS | A:263 | A:242 | 67.0 | 0.335 | E | -109.9 | 146.5 | 67.0 | 0.335 | 0.0 |
HOH |
8.618 |
N |
O |
||
LYS | B:263 | B:242 | 93.0 | 0.465 | E | -101.8 | 143.6 | 93.0 | 0.465 | 0.0 | |||||||||||||
LYS | C:263 | C:242 | 89.0 | 0.445 | E | -101.1 | 143.7 | NA | NA | NA | |||||||||||||
LYS | D:263 | D:242 | 83.0 | 0.415 | E | -99.7 | 139.3 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | LYS | A:242 | A:242 | 69.0 | 0.345 | E | -114.7 | 151.5 | 69.0 | 0.345 | 0.0 |
HOH |
5.153 |
CA |
O |
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LYS | B:242 | B:242 | 78.0 | 0.39 | E | -129.5 | 140.3 | 78.0 | 0.39 | 0.0 |
HOH |
9.503 |
O |
O |
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LYS | C:242 | C:242 | 89.0 | 0.445 | E | -106.7 | 157.3 | NA | NA | NA | |||||||||||||
LYS | D:242 | D:242 | 87.0 | 0.435 | E | -131.6 | 157.9 | NA | NA | NA | |||||||||||||
LYS | E:242 | E:242 | 63.0 | 0.315 | E | -135.5 | 140.0 | NA | NA | NA | |||||||||||||
LYS | F:242 | F:242 | 66.0 | 0.33 | E | -115.4 | 158.1 | NA | NA | NA | |||||||||||||
LYS | G:242 | G:242 | 79.0 | 0.395 | E | -90.7 | 145.5 | NA | NA | NA | |||||||||||||
LYS | H:242 | H:242 | 72.0 | 0.36 | -129.5 | 139.1 | NA | NA | NA | ||||||||||||||
LYS | I:242 | I:242 | 89.0 | 0.445 | E | -111.6 | 177.2 | NA | NA | NA | |||||||||||||
LYS | J:242 | J:242 | 74.0 | 0.37 | E | -121.8 | 162.0 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 92.0 | 0.46 | E | -105.8 | 142.3 | 92.0 | 0.46 | 0.0 |
HOH |
2.803 |
HG3 |
O |
||
LYS | B:264 | B:242 | 69.0 | 0.345 | E | -106.5 | 146.8 | 69.0 | 0.345 | 0.0 |
HOH |
2.706 |
HA |
O |
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6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 59.0 | 0.295 | E | -105.2 | 143.0 | 59.0 | 0.295 | 0.0 | ||||||
LYS | B:264 | B:242 | 67.0 | 0.335 | E | -105.1 | 145.7 | 67.0 | 0.335 | 0.0 |
HOH |
4.937 |
HA |
O |
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1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | LYS | A:242 | A:242 | 69.0 | 0.345 | E | -100.7 | 135.9 | 69.0 | 0.345 | 0.0 |
NAD HOH |
3.575 7.701 |
CA N |
N1A O |
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LYS | B:242 | B:242 | 74.0 | 0.37 | E | -94.0 | 133.0 | 74.0 | 0.37 | 0.0 |
NAD HOH |
3.934 5.851 |
CA O |
N1A O |
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LYS | C:242 | C:242 | 105.0 | 0.525 | E | -104.1 | 127.2 | NA | NA | NA | |||||||||||||
LYS | D:242 | D:242 | 63.0 | 0.315 | -115.1 | 133.6 | NA | NA | NA | ||||||||||||||
LYS | E:242 | E:242 | 92.0 | 0.46 | E | -102.1 | 132.0 | NA | NA | NA | |||||||||||||
LYS | F:242 | F:242 | 60.0 | 0.3 | E | -106.5 | 139.1 | NA | NA | NA | |||||||||||||
LYS | G:242 | G:242 | 76.0 | 0.38 | E | -106.0 | 126.7 | NA | NA | NA | |||||||||||||
LYS | H:242 | H:242 | 98.0 | 0.49 | E | -98.1 | 125.1 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | LYS | A:242 | A:242 | 58.0 | 0.29 | E | -116.9 | 140.0 | 58.0 | 0.29 | 0.0 |
NAI |
4.198 |
CA |
N1A |
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LYS | B:242 | B:242 | 76.0 | 0.38 | E | -99.9 | 146.4 | 76.0 | 0.38 | 0.0 |
NAI HOH |
5.271 3.593 |
CA CA |
N1A O |
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LYS | C:242 | C:242 | 90.0 | 0.45 | E | -110.8 | 136.5 | NA | NA | NA | |||||||||||||
LYS | D:242 | D:242 | 61.0 | 0.305 | E | -118.3 | 146.4 | NA | NA | NA | |||||||||||||
LYS | E:242 | E:242 | 91.0 | 0.455 | E | -112.9 | 152.1 | NA | NA | NA | |||||||||||||
LYS | F:242 | F:242 | 68.0 | 0.34 | E | -110.2 | 139.4 | NA | NA | NA | |||||||||||||
LYS | G:242 | G:242 | 81.0 | 0.405 | E | -104.1 | 128.9 | NA | NA | NA | |||||||||||||
LYS | H:242 | H:242 | 95.0 | 0.475 | E | -102.9 | 140.3 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | LYS | A:242 | A:242 | 69.0 | 0.345 | E | -112.8 | 152.0 | 69.0 | 0.345 | 0.0 |
HOH |
2.828 |
NZ |
O |
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LYS | B:242 | B:242 | 87.0 | 0.435 | E | -110.2 | 148.6 | 87.0 | 0.435 | 0.0 |
HOH |
4.263 |
CA |
O |
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LYS | C:242 | C:242 | 85.0 | 0.425 | E | -123.8 | 145.9 | NA | NA | NA | |||||||||||||
LYS | D:242 | D:242 | 67.0 | 0.335 | E | -109.9 | 138.3 | NA | NA | NA | |||||||||||||
LYS | E:242 | E:242 | 85.0 | 0.425 | E | -115.7 | 154.3 | NA | NA | NA | |||||||||||||
LYS | F:242 | F:242 | 107.0 | 0.535 | E | -104.8 | 142.9 | NA | NA | NA | |||||||||||||
LYS | G:242 | G:242 | 70.0 | 0.35 | E | -110.2 | 147.1 | NA | NA | NA | |||||||||||||
LYS | H:242 | H:242 | 81.0 | 0.405 | E | -118.7 | 151.9 | NA | NA | NA | |||||||||||||
LYS | I:242 | I:242 | 72.0 | 0.36 | E | -105.2 | 149.6 | NA | NA | NA | |||||||||||||
LYS | J:242 | J:242 | 113.0 | 0.565 | E | -104.6 | 134.1 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | LYS | A:263 | A:242 | 83.0 | 0.415 | E | -107.4 | 143.3 | 83.0 | 0.415 | 0.0 | ||||||
LYS | B:263 | B:242 | 67.0 | 0.335 | E | -108.8 | 142.6 | 67.0 | 0.335 | 0.0 |
HOH |
7.184 |
HD2 |
O |
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LYS | C:263 | C:242 | 77.0 | 0.385 | E | -107.5 | 145.4 | NA | NA | NA | |||||||||||||
LYS | D:263 | D:242 | 58.0 | 0.29 | E | -110.8 | 145.2 | NA | NA | NA | |||||||||||||
LYS | E:263 | E:242 | 70.0 | 0.35 | E | -108.7 | 145.6 | NA | NA | NA | |||||||||||||
LYS | F:263 | F:242 | 79.0 | 0.395 | E | -111.8 | 147.9 | NA | NA | NA | |||||||||||||
LYS | G:263 | G:242 | 75.0 | 0.375 | E | -108.4 | 142.8 | NA | NA | NA | |||||||||||||
LYS | H:263 | H:242 | 93.0 | 0.465 | E | -108.3 | 147.1 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 60.0 | 0.3 | E | -103.7 | 144.8 | 60.0 | 0.3 | 0.0 |
HOH |
2.850 |
HA |
O |
||
LYS | B:264 | B:242 | 72.0 | 0.36 | E | -104.2 | 145.0 | 72.0 | 0.36 | 0.0 |
HOH |
5.350 |
HA |
O |
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5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | LYS | A:264 | A:242 | 72.0 | 0.36 | E | -106.5 | 148.8 | 72.0 | 0.36 | 0.0 |
HOH |
5.856 |
CA |
O |
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LYS | B:264 | B:242 | 75.0 | 0.375 | E | -109.1 | 154.9 | 75.0 | 0.375 | 0.0 |
HOH |
3.464 |
CA |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | LYS | A:264 | A:242 | 74.0 | 0.37 | E | -103.5 | 143.1 | 74.0 | 0.37 | 0.0 |
HOH |
2.764 |
NZ |
O |
||
LYS | B:264 | B:242 | 71.0 | 0.355 | E | -112.5 | 146.6 | 71.0 | 0.355 | 0.0 |
HOH |
3.769 |
CA |
O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 86.0 | 0.43 | E | -105.6 | 141.2 | 86.0 | 0.43 | 0.0 |
HOH |
2.394 |
HE3 |
O |
||
LYS | B:264 | B:242 | 58.0 | 0.29 | E | -106.9 | 143.9 | 58.0 | 0.29 | 0.0 |
HOH |
3.021 |
HA |
O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 82.0 | 0.41 | E | -106.2 | 146.3 | 82.0 | 0.41 | 0.0 |
HOH |
2.823 |
HA |
O |
||
LYS | B:264 | B:242 | 59.0 | 0.295 | E | -106.0 | 146.4 | 59.0 | 0.295 | 0.0 |
HOH |
2.656 |
HA |
O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 63.0 | 0.315 | E | -107.3 | 147.1 | 63.0 | 0.315 | 0.0 |
HOH |
2.616 |
HA |
O |
||
LYS | B:264 | B:242 | 72.0 | 0.36 | E | -107.5 | 148.0 | 72.0 | 0.36 | 0.0 |
HOH |
2.911 |
HA |
O |
|||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:264 | A:242 | 67.0 | 0.335 | E | -114.8 | 160.3 | 67.0 | 0.335 | 0.0 |
HOH |
3.460 |
HB2 |
O |
||
LYS | B:264 | B:242 | 96.0 | 0.48 | E | -108.9 | 155.4 | 96.0 | 0.48 | 0.0 | |||||||||||||
LYS | C:264 | C:242 | 63.0 | 0.315 | E | -115.7 | 158.6 | NA | NA | NA | |||||||||||||
LYS | D:264 | D:242 | 78.0 | 0.39 | E | -114.0 | 165.1 | NA | NA | NA | |||||||||||||
LYS | E:264 | E:242 | 90.0 | 0.45 | E | -114.2 | 155.7 | NA | NA | NA | |||||||||||||
LYS | F:264 | F:242 | 98.0 | 0.49 | E | -112.4 | 150.5 | NA | NA | NA | |||||||||||||
LYS | G:264 | G:242 | 79.0 | 0.395 | E | -113.7 | 155.3 | NA | NA | NA | |||||||||||||
LYS | H:264 | H:242 | 77.0 | 0.385 | E | -113.8 | 153.6 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | LYS | A:277 | A:277 | 77.0 | 0.385 | E | -99.3 | 135.2 |