Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557261 . A C CCDS5749.1:NM_000108.3:c.898Aaa>Caa_NP_000099.2:p.300K>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 LYS A:286 A:265 163.0 0.815 44.2 33.6 163.0 0.815 0.0 HOH
 6.217
 O
 O
LYS B:286 B:265 168.0 0.84 -117.4 91.4 168.0 0.84 0.0
LYS C:286 C:265 159.0 0.795 80.0 30.3 NA NA NA
LYS D:286 D:265 165.0 0.825 62.7 74.8 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 LYS A:265 A:265 146.0 0.73 -87.4 53.8 146.0 0.73 0.0 HOH
 3.190
 O
 O
LYS B:265 B:265 148.0 0.74 -79.3 85.4 148.0 0.74 0.0
LYS C:265 C:265 161.0 0.805 -70.6 87.0 NA NA NA
LYS D:265 D:265 171.0 0.855 -78.6 68.4 NA NA NA
LYS E:265 E:265 148.0 0.74 -80.1 85.2 NA NA NA
LYS F:265 F:265 148.0 0.74 -86.0 78.3 NA NA NA
LYS G:265 G:265 141.0 0.705 -81.5 42.6 NA NA NA
LYS H:265 H:265 151.0 0.755 -100.2 74.6 NA NA NA
LYS I:265 I:265 169.0 0.845 -89.2 80.2 NA NA NA
LYS J:265 J:265 129.0 0.645 -101.4 92.3 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 136.0 0.68 -159.6 72.4 136.0 0.68 0.0 HOH
 7.501
 HZ3
 O
LYS B:287 B:265 158.0 0.79 55.1 68.5 158.0 0.79 0.0 HOH
 7.194
 HZ3
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 134.0 0.67 -112.5 66.2 134.0 0.67 0.0 HOH
 8.711
 HE2
 O
LYS B:287 B:265 129.0 0.645 -109.4 70.5 129.0 0.645 0.0 HOH
 7.420
 HZ1
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:265 A:265 142.0 0.71 -95.6 44.8 142.0 0.71 0.0 HOH
 4.068
 CA
 O
LYS B:265 B:265 146.0 0.73 53.3 47.5 146.0 0.73 0.0 HOH
 2.693
 O
 O
LYS C:265 C:265 132.0 0.66 52.5 35.0 NA NA NA
LYS D:265 D:265 158.0 0.79 49.1 33.9 NA NA NA
LYS E:265 E:265 123.0 0.615 35.3 62.3 NA NA NA
LYS F:265 F:265 137.0 0.685 61.1 45.7 NA NA NA
LYS G:265 G:265 147.0 0.735 59.8 54.6 NA NA NA
LYS H:265 H:265 126.0 0.63 52.9 43.3 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:265 A:265 154.0 0.77 49.9 17.0 154.0 0.77 0.0
LYS B:265 B:265 143.0 0.715 50.0 48.3 143.0 0.715 0.0 HOH
 2.762
 O
 O
LYS C:265 C:265 142.0 0.71 55.6 42.2 NA NA NA
LYS D:265 D:265 164.0 0.82 49.1 31.3 NA NA NA
LYS E:265 E:265 137.0 0.685 31.7 76.7 NA NA NA
LYS F:265 F:265 142.0 0.71 53.9 40.3 NA NA NA
LYS G:265 G:265 152.0 0.76 59.8 43.7 NA NA NA
LYS H:265 H:265 147.0 0.735 48.6 55.5 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 LYS A:265 A:265 176.0 0.88 49.0 45.7 176.0 0.88 0.0 HOH
 2.740
 O
 O
LYS B:265 B:265 138.0 0.69 47.5 52.4 138.0 0.69 0.0
LYS C:265 C:265 158.0 0.79 0.8 99.4 NA NA NA
LYS D:265 D:265 150.0 0.75 53.5 37.7 NA NA NA
LYS E:265 E:265 178.0 0.89 50.9 42.1 NA NA NA
LYS F:265 F:265 150.0 0.75 46.5 57.9 NA NA NA
LYS G:265 G:265 150.0 0.75 44.1 -176.6 NA NA NA
LYS H:265 H:265 165.0 0.825 52.2 40.9 NA NA NA
LYS I:265 I:265 156.0 0.78 360.0 91.7 NA NA NA
LYS J:265 J:265 150.0 0.75 60.3 35.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 LYS A:286 A:265 159.0 0.795 62.1 41.3 159.0 0.795 0.0 HOH
 8.236
 O
 O
LYS B:286 B:265 160.0 0.8 49.5 38.9 160.0 0.8 0.0 HOH
 9.909
 HE2
 O
LYS C:286 C:265 162.0 0.81 49.3 44.7 NA NA NA
LYS D:286 D:265 175.0 0.875 53.3 38.7 NA NA NA
LYS E:286 E:265 164.0 0.82 53.2 38.8 NA NA NA
LYS F:286 F:265 162.0 0.81 52.2 37.8 NA NA NA
LYS G:286 G:265 179.0 0.895 50.2 38.6 NA NA NA
LYS H:286 H:265 173.0 0.865 57.6 40.2 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 162.0 0.81 50.1 59.7 162.0 0.81 0.0 HOH
 9.845
 HZ3
 O
LYS B:287 B:265 174.0 0.87 48.5 57.9 174.0 0.87 0.0 HOH
 8.301
 HZ1
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 LYS A:287 A:265 153.0 0.765 42.0 56.0 153.0 0.765 0.0 HOH
 5.770
 O
 O
LYS B:287 B:265 157.0 0.785 74.6 40.3 157.0 0.785 0.0 HOH
 4.178
 CD
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 LYS A:287 A:265 159.0 0.795 31.6 71.3 159.0 0.795 0.0 HOH
 2.557
 N
 O
LYS B:287 B:265 158.0 0.79 55.4 39.3 158.0 0.79 0.0 HOH
 2.785
 O
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 163.0 0.815 51.4 49.3 163.0 0.815 0.0 HOH
 2.713
 O
 O
LYS B:287 B:265 155.0 0.775 51.2 49.8 155.0 0.775 0.0 HOH
 2.694
 O
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 163.0 0.815 47.5 57.9 163.0 0.815 0.0 HOH
 3.235
 HE2
 O
LYS B:287 B:265 150.0 0.75 47.6 59.4 150.0 0.75 0.0 HOH
 5.777
 O
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 160.0 0.8 55.5 54.2 160.0 0.8 0.0 HOH
 2.302
 HZ3
 O
LYS B:287 B:265 160.0 0.8 55.0 51.8 160.0 0.8 0.0 HOH
 2.746
 O
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:287 A:265 188.0 0.94 -64.0 136.1 188.0 0.94 0.0 HOH
 2.135
 H
 O
LYS B:287 B:265 169.0 0.845 43.4 70.0 169.0 0.845 0.0
LYS C:287 C:265 184.0 0.92 -66.0 137.8 NA NA NA
LYS D:287 D:265 179.0 0.895 29.2 64.6 NA NA NA
LYS E:287 E:265 192.0 0.96 46.8 71.2 NA NA NA
LYS F:287 F:265 183.0 0.915 39.4 69.5 NA NA NA
LYS G:287 G:265 189.0 0.945 40.7 52.3 NA NA NA
LYS H:287 H:265 178.0 0.89 54.7 69.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:300 A:300 198.0 0.99 -62.2 123.1