Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557299 . C A CCDS5749.1:NM_000108.3:c.936tgC>tgA_NP_000099.2:p.312C>* Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 CYS A:298 A:277 21.0 0.156 -136.3 53.3 21.0 0.156 0.0 BME
FAD
HOH
 2.036
6.590
3.111
 SG
SG
O
 S2
C7M
O
CYS B:298 B:277 17.0 0.126 -120.0 60.9 17.0 0.126 0.0 BME
FAD
 2.043
6.577
 SG
SG
 S2
C7M
CYS C:298 C:277 20.0 0.148 -134.7 52.7 NA NA NA
CYS D:298 D:277 21.0 0.156 -140.3 50.9 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 CYS A:277 A:277 20.0 0.148 -125.8 58.7 20.0 0.148 0.0 FAD
HOH
 6.714
4.088
 SG
SG
 C7M
O
CYS B:277 B:277 17.0 0.126 -144.6 90.3 17.0 0.126 0.0 FAD
HOH
 7.584
3.029
 CB
CB
 C7M
O
CYS C:277 C:277 16.0 0.119 -141.0 81.2 NA NA NA
CYS D:277 D:277 15.0 0.111 -134.8 83.3 NA NA NA
CYS E:277 E:277 23.0 0.17 -126.4 33.0 NA NA NA
CYS F:277 F:277 14.0 0.104 -129.4 87.4 NA NA NA
CYS G:277 G:277 10.0 0.074 -117.2 54.9 NA NA NA
CYS H:277 H:277 14.0 0.104 -129.7 47.5 NA NA NA
CYS I:277 I:277 16.0 0.119 -116.0 63.0 NA NA NA
CYS J:277 J:277 15.0 0.111 -158.1 78.3 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 16.0 0.119 -141.0 72.5 16.0 0.119 0.0 FAD
BTB
HOH
 6.347
9.914
2.567
 HB3
HA
HA
 HM72
HO1
O
CYS B:299 B:277 17.0 0.126 -141.3 73.2 17.0 0.126 0.0 FAD
HOH
 6.444
2.449
 HB3
HA
 HM72
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 15.0 0.111 -139.8 69.4 15.0 0.111 0.0 FAD
HOH
 6.031
2.544
 HB3
HA
 HM72
O
CYS B:299 B:277 17.0 0.126 -139.5 70.2 17.0 0.126 0.0 FAD
HOH
 6.127
2.510
 HB3
HA
 HM72
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 CYS A:277 A:277 17.0 0.126 -131.3 66.1 17.0 0.126 0.0 FAD
NAD
HOH
 6.600
3.426
3.225
 SG
O
SG
 C7M
C5B
O
CYS B:277 B:277 19.0 0.141 -129.9 56.0 19.0 0.141 0.0 FAD
NAD
HOH
 6.692
3.398
3.203
 SG
O
C
 C7M
C5B
O
CYS C:277 C:277 18.0 0.133 -135.4 59.9 NA NA NA
CYS D:277 D:277 18.0 0.133 -145.7 72.9 NA NA NA
CYS E:277 E:277 18.0 0.133 -140.7 58.5 NA NA NA
CYS F:277 F:277 20.0 0.148 -132.6 55.5 NA NA NA
CYS G:277 G:277 18.0 0.133 -130.5 56.0 NA NA NA
CYS H:277 H:277 17.0 0.126 -142.3 62.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 CYS A:277 A:277 13.0 0.096 -138.9 74.4 13.0 0.096 0.0 FAD
NAI
HOH
 7.805
3.553
2.939
 CB
O
O
 C7M
C5B
O
CYS B:277 B:277 12.0 0.089 -146.5 73.2 12.0 0.089 0.0 FAD
NAI
HOH
 8.021
3.498
3.080
 CB
O
O
 C7M
C5B
O
CYS C:277 C:277 11.0 0.081 -143.2 71.3 NA NA NA
CYS D:277 D:277 12.0 0.089 -143.3 76.4 NA NA NA
CYS E:277 E:277 11.0 0.081 -151.1 75.1 NA NA NA
CYS F:277 F:277 13.0 0.096 -147.0 76.8 NA NA NA
CYS G:277 G:277 13.0 0.096 -137.4 78.5 NA NA NA
CYS H:277 H:277 10.0 0.074 -145.8 71.8 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 CYS A:277 A:277 16.0 0.119 -148.5 64.9 16.0 0.119 0.0 FAD
HOH
 7.486
3.028
 CB
O
 C7M
O
CYS B:277 B:277 17.0 0.126 -147.9 71.3 17.0 0.126 0.0 FAD
HOH
 7.797
2.984
 CB
CA
 C7M
O
CYS C:277 C:277 18.0 0.133 -157.2 76.2 NA NA NA
CYS D:277 D:277 16.0 0.119 -143.3 72.2 NA NA NA
CYS E:277 E:277 17.0 0.126 -140.3 75.5 NA NA NA
CYS F:277 F:277 17.0 0.126 -142.5 71.3 NA NA NA
CYS G:277 G:277 16.0 0.119 -136.9 70.8 NA NA NA
CYS H:277 H:277 16.0 0.119 -140.1 68.5 NA NA NA
CYS I:277 I:277 19.0 0.141 -136.6 78.3 NA NA NA
CYS J:277 J:277 15.0 0.111 -148.5 72.9 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 CYS A:298 A:277 18.0 0.133 -139.4 67.2 18.0 0.133 0.0 FAD
HOH
 5.954
2.730
 HB3
HB3
 HM81
O
CYS B:298 B:277 21.0 0.156 -134.9 52.9 21.0 0.156 0.0 FAD
HOH
 5.801
2.839
 HG
HA
 HM73
O
CYS C:298 C:277 20.0 0.148 -132.8 55.5 NA NA NA
CYS D:298 D:277 17.0 0.126 -135.5 57.0 NA NA NA
CYS E:298 E:277 18.0 0.133 -133.1 56.3 NA NA NA
CYS F:298 F:277 19.0 0.141 -136.4 58.9 NA NA NA
CYS G:298 G:277 19.0 0.141 -134.2 57.6 NA NA NA
CYS H:298 H:277 14.0 0.104 -136.1 58.6 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 16.0 0.119 -138.0 67.3 16.0 0.119 0.0 FAD
HOH
 5.998
2.589
 HB3
HA
 HM72
O
CYS B:299 B:277 17.0 0.126 -139.9 69.7 17.0 0.126 0.0 FAD
HOH
 6.015
2.448
 HB3
HA
 HM72
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 CYS A:299 A:277 20.0 0.148 -142.3 68.8 20.0 0.148 0.0 HOH
 2.859
 O
 O
CYS B:299 B:277 20.0 0.148 -141.1 74.0 20.0 0.148 0.0 HOH
 2.862
 O
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 CYS A:299 A:277 16.0 0.119 -142.9 69.7 16.0 0.119 0.0 HOH
 3.255
 CA
 O
CYS B:299 B:277 19.0 0.141 -143.1 66.2 19.0 0.141 0.0 HOH
 3.188
 CA
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 19.0 0.141 -144.7 67.1 19.0 0.141 0.0 HOH
 2.797
 O
 O
CYS B:299 B:277 19.0 0.141 -144.7 65.2 19.0 0.141 0.0 HOH
 2.791
 O
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 19.0 0.141 -139.0 55.9 19.0 0.141 0.0 HOH
 5.020
 O
 O
CYS B:299 B:277 20.0 0.148 -140.0 53.5 20.0 0.148 0.0 HOH
 2.800
 O
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 19.0 0.141 -140.1 65.4 19.0 0.141 0.0 FAD
HOH
 6.207
2.644
 HB3
HA
 HM72
O
CYS B:299 B:277 19.0 0.141 -138.2 63.3 19.0 0.141 0.0 FAD
SO4
HOH
 6.169
9.212
2.687
 HB3
HA
HA
 HM72
O4
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 CYS A:299 A:277 21.0 0.156 -137.1 78.6 21.0 0.156 0.0 FAD
HOH
 5.955
2.439
 HB3
HA
 HM73
O
CYS B:299 B:277 17.0 0.126 -138.0 80.1 17.0 0.126 0.0 FAD
HOH
 6.283
8.226
 HB3
O
 HM71
O
CYS C:299 C:277 20.0 0.148 -137.4 79.2 NA NA NA
CYS D:299 D:277 19.0 0.141 -135.7 79.6 NA NA NA
CYS E:299 E:277 20.0 0.148 -136.6 80.6 NA NA NA
CYS F:299 F:277 18.0 0.133 -140.6 81.4 NA NA NA
CYS G:299 G:277 19.0 0.141 -137.3 61.4 NA NA NA
CYS H:299 H:277 17.0 0.126 -135.7 81.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 CYS A:312 A:312 18.0 0.133 -137.3 45.0