Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557307 . G A CCDS5749.1:NM_000108.3:c.944cGa>cAa_NP_000099.2:p.315R>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ARG A:301 A:280 54.0 0.24 E -135.1 159.7 54.0 0.24 0.0 BME
FAD
HOH
 2.867
3.581
2.482
 NH1
NH1
NH1
 O1
C8M
O
ARG B:301 B:280 42.0 0.187 E -139.6 159.9 42.0 0.187 0.0 BME
FAD
HOH
 3.174
3.432
9.440
 NH1
NH1
NE
 O1
C8M
O
ARG C:301 C:280 49.0 0.218 E -129.4 164.8 NA NA NA
ARG D:301 D:280 50.0 0.222 E -128.7 157.5 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ARG A:280 A:280 64.0 0.284 E -149.4 137.1 64.0 0.284 0.0 FAD
HOH
 3.783
3.666
 NE
CG
 C8M
O
ARG B:280 B:280 49.0 0.218 E -122.0 154.1 49.0 0.218 0.0 FAD
HOH
 4.001
4.349
 NE
NH2
 C8M
O
ARG C:280 C:280 56.0 0.249 E -127.6 164.3 NA NA NA
ARG D:280 D:280 52.0 0.231 E -136.2 162.6 NA NA NA
ARG E:280 E:280 55.0 0.244 E -143.8 113.3 NA NA NA
ARG F:280 F:280 53.0 0.236 E -142.6 142.8 NA NA NA
ARG G:280 G:280 71.0 0.316 E -122.8 162.1 NA NA NA
ARG H:280 H:280 43.0 0.191 E -116.7 172.2 NA NA NA
ARG I:280 I:280 61.0 0.271 E -134.8 152.9 NA NA NA
ARG J:280 J:280 64.0 0.284 E -122.5 144.2 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 53.0 0.236 E -132.8 157.0 53.0 0.236 0.0 FAD
BTB
SO4
HOH
 2.007
2.135
9.667
2.016
 HD2
HH22
O
HH12
 HM83
HO1
O4
O
ARG B:302 B:280 53.0 0.236 E -131.6 157.4 53.0 0.236 0.0 FAD
BTB
SO4
HOH
 2.027
3.017
9.692
1.978
 HD2
HH22
O
HH12
 HM82
H31
O2
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 46.0 0.204 E -133.0 156.6 46.0 0.204 0.0 FAD
SO4
HOH
 2.058
9.771
1.873
 HD2
O
HH12
 HM83
O4
O
ARG B:302 B:280 52.0 0.231 E -133.6 155.8 52.0 0.231 0.0 FAD
SO4
HOH
 2.151
9.569
2.008
 HD2
O
HH12
 HM82
O4
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:280 A:280 51.0 0.227 E -136.2 159.3 51.0 0.227 0.0 FAD
NAD
HOH
 3.564
2.763
2.864
 NH1
O
NH1
 C8M
O2D
O
ARG B:280 B:280 51.0 0.227 E -130.2 160.3 51.0 0.227 0.0 SO4
FAD
NAD
HOH
 9.913
3.660
4.894
2.928
 O
NH1
N
NH1
 O4
C8M
O1A
O
ARG C:280 C:280 52.0 0.231 E -132.8 153.4 NA NA NA
ARG D:280 D:280 50.0 0.222 E -137.5 163.5 NA NA NA
ARG E:280 E:280 51.0 0.227 E -124.2 161.0 NA NA NA
ARG F:280 F:280 51.0 0.227 E -140.0 150.0 NA NA NA
ARG G:280 G:280 51.0 0.227 E -137.6 151.9 NA NA NA
ARG H:280 H:280 50.0 0.222 E -122.1 164.1 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:280 A:280 58.0 0.258 E -128.7 164.3 58.0 0.258 0.0 SO4
FAD
NAI
HOH
 9.858
3.553
3.678
2.768
 O
NH1
CG
NH1
 O2
C8M
C5D
O
ARG B:280 B:280 57.0 0.253 E -133.2 162.2 57.0 0.253 0.0 SO4
FAD
NAI
HOH
 9.239
3.771
3.729
2.653
 O
NH1
CG
O
 O4
C8M
C5D
O
ARG C:280 C:280 57.0 0.253 E -131.9 162.0 NA NA NA
ARG D:280 D:280 55.0 0.244 E -129.7 165.2 NA NA NA
ARG E:280 E:280 55.0 0.244 E -128.7 160.7 NA NA NA
ARG F:280 F:280 56.0 0.249 E -131.9 160.4 NA NA NA
ARG G:280 G:280 57.0 0.253 E -130.4 157.0 NA NA NA
ARG H:280 H:280 51.0 0.227 E -134.5 162.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ARG A:280 A:280 54.0 0.24 E -135.6 154.5 54.0 0.24 0.0 SO4
FAD
HOH
 9.526
3.354
2.529
 O
NH1
NH1
 O2
C8M
O
ARG B:280 B:280 57.0 0.253 E -131.4 160.6 57.0 0.253 0.0 FAD
HOH
 3.383
2.844
 NH1
NH1
 C8M
O
ARG C:280 C:280 57.0 0.253 E -134.6 153.4 NA NA NA
ARG D:280 D:280 51.0 0.227 E -140.0 151.7 NA NA NA
ARG E:280 E:280 53.0 0.236 E -134.1 159.1 NA NA NA
ARG F:280 F:280 52.0 0.231 E -131.7 155.4 NA NA NA
ARG G:280 G:280 54.0 0.24 E -137.3 154.1 NA NA NA
ARG H:280 H:280 53.0 0.236 E -136.9 153.8 NA NA NA
ARG I:280 I:280 52.0 0.231 E -142.4 153.0 NA NA NA
ARG J:280 J:280 53.0 0.236 E -134.3 153.7 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ARG A:301 A:280 49.0 0.218 E -129.3 150.6 49.0 0.218 0.0 FAD
TRS
HOH
 2.235
3.542
2.147
 HD2
HH22
HH11
 HM82
C1
O
ARG B:301 B:280 53.0 0.236 E -131.2 149.9 53.0 0.236 0.0 FAD
HOH
 2.358
2.113
 HD2
HH11
 HM83
O
ARG C:301 C:280 51.0 0.227 E -131.4 150.2 NA NA NA
ARG D:301 D:280 55.0 0.244 E -131.2 151.8 NA NA NA
ARG E:301 E:280 54.0 0.24 E -130.6 149.7 NA NA NA
ARG F:301 F:280 55.0 0.244 E -130.1 152.3 NA NA NA
ARG G:301 G:280 51.0 0.227 E -133.6 151.1 NA NA NA
ARG H:301 H:280 61.0 0.271 E -133.2 151.5 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 52.0 0.231 E -133.9 155.5 52.0 0.231 0.0 FAD
SO4
HOH
 2.056
9.703
1.940
 HD2
O
HH12
 HM83
O4
O
ARG B:302 B:280 53.0 0.236 E -132.9 156.0 53.0 0.236 0.0 FAD
SO4
HOH
 2.098
9.617
2.121
 HD2
O
HH12
 HM82
O1
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ARG A:302 A:280 56.0 0.249 E -136.5 152.2 56.0 0.249 0.0 FAD
PO4
HOH
 3.506
9.976
2.801
 NH1
O
NH1
 C8M
O4
O
ARG B:302 B:280 52.0 0.231 E -135.3 154.2 52.0 0.231 0.0 FAD
PO4
HOH
 3.508
9.900
2.588
 NH1
O
O
 C8M
O1
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ARG A:302 A:280 57.0 0.253 E -137.2 155.3 57.0 0.253 0.0 FAD
SO4
HOH
 3.421
9.764
2.736
 NH2
O
NH2
 C8M
O4
O
ARG B:302 B:280 56.0 0.249 E -133.8 160.7 56.0 0.249 0.0 FAD
SO4
SO4
HOH
 3.529
5.302
9.759
2.745
 NH1
N
O
O
 C8M
O1
O1
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 56.0 0.249 E -132.0 158.9 56.0 0.249 0.0 FAD
SO4
BTB
HOH
 2.254
9.771
2.040
2.038
 HD2
O
HH22
HH12
 HM82
O4
HO1
O
ARG B:302 B:280 56.0 0.249 E -131.4 159.2 56.0 0.249 0.0 FAD
SO4
BTB
HOH
 2.301
9.768
2.137
2.113
 HD2
O
HH22
HH12
 HM81
O2
HO4
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 52.0 0.231 E -131.7 159.2 52.0 0.231 0.0 FAD
SO4
BTB
HOH
 2.304
9.743
2.333
1.992
 HD2
O
HH22
HH12
 HM83
O2
HO3
O
ARG B:302 B:280 53.0 0.236 E -128.7 160.3 53.0 0.236 0.0 FAD
SO4
BTB
HOH
 2.212
9.590
2.123
1.943
 HD2
O
HH22
HH12
 HM82
O2
HO4
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 55.0 0.244 E -134.7 155.4 55.0 0.244 0.0 FAD
SO4
HOH
 2.293
9.596
2.086
 HD2
O
HH12
 HM83
O4
O
ARG B:302 B:280 52.0 0.231 E -134.1 154.6 52.0 0.231 0.0 FAD
SO4
SO4
HOH
 2.193
9.703
3.658
2.077
 HD2
O
HH12
HH11
 HM82
O2
O4
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:302 A:280 50.0 0.222 E -135.9 156.3 50.0 0.222 0.0 FAD
SO4
HOH
 2.493
9.555
1.995
 HD2
O
HH12
 HM81
O1
O
ARG B:302 B:280 63.0 0.28 E -132.3 156.4 63.0 0.28 0.0 FAD
SO4
 2.668
9.046
 HD3
O
 HM83
O3
ARG C:302 C:280 53.0 0.236 E -133.4 159.5 NA NA NA
ARG D:302 D:280 59.0 0.262 E -135.0 157.6 NA NA NA
ARG E:302 E:280 66.0 0.293 E -135.6 155.3 NA NA NA
ARG F:302 F:280 60.0 0.267 E -134.0 157.2 NA NA NA
ARG G:302 G:280 63.0 0.28 E -135.0 155.6 NA NA NA
ARG H:302 H:280 62.0 0.276 E -133.5 154.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ARG A:315 A:315 55.0 0.244 E -125.7 154.2