Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557318 . A C CCDS5749.1:NM_000108.3:c.955Act>Cct_NP_000099.2:p.319T>P Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 THR A:305 A:284 18.0 0.129 -135.8 10.1 18.0 0.129 0.0 FAD
HOH
 6.239
2.406
 N
OG1
 N7A
O
THR B:305 B:284 21.0 0.15 -138.0 18.2 21.0 0.15 0.0 FAD
 6.093
 N
 N7A
THR C:305 C:284 21.0 0.15 -131.0 24.2 NA NA NA
THR D:305 D:284 26.0 0.186 -133.8 5.6 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 THR A:284 A:284 21.0 0.15 -133.9 5.1 21.0 0.15 0.0 FAD
HOH
 6.132
3.055
 N
N
 N7A
O
THR B:284 B:284 24.0 0.171 -155.9 31.6 24.0 0.171 0.0 FAD
HOH
 5.932
3.641
 N
C
 N7A
O
THR C:284 C:284 23.0 0.164 -137.2 10.7 NA NA NA
THR D:284 D:284 14.0 0.1 -135.3 6.7 NA NA NA
THR E:284 E:284 23.0 0.164 -144.0 9.4 NA NA NA
THR F:284 F:284 30.0 0.214 -142.2 6.4 NA NA NA
THR G:284 G:284 20.0 0.143 -130.8 27.3 NA NA NA
THR H:284 H:284 5.0 0.036 -151.1 30.1 NA NA NA
THR I:284 I:284 15.0 0.107 -109.7 -23.6 NA NA NA
THR J:284 J:284 11.0 0.079 -122.5 2.2 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 THR A:306 A:284 25.0 0.179 -138.5 15.3 25.0 0.179 0.0 FAD
BTB
SO4
HOH
 5.450
6.475
3.317
2.177
 HA
N
O
H
 H61A
H62
O3
O
THR B:306 B:284 25.0 0.179 -141.1 17.1 25.0 0.179 0.0 FAD
BTB
SO4
HOH
 5.202
6.342
3.464
2.124
 HA
N
O
H
 H62A
H82
O2
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:306 A:284 26.0 0.186 -136.1 17.4 26.0 0.186 0.0 FAD
SO4
HOH
 5.341
3.342
1.930
 HA
O
H
 H61A
O3
O
THR B:306 B:284 26.0 0.186 -137.2 17.9 26.0 0.186 0.0 FAD
SO4
HOH
 5.155
3.383
2.164
 HA
O
H
 H61A
O2
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 THR A:284 A:284 25.0 0.179 -132.2 20.8 25.0 0.179 0.0 SO4
FAD
HOH
 3.459
6.146
2.674
 O
CA
OG1
 O3
N7A
O
THR B:284 B:284 18.0 0.129 -143.1 4.0 18.0 0.129 0.0 FAD
HOH
 6.196
2.439
 N
OG1
 N7A
O
THR C:284 C:284 20.0 0.143 -141.4 14.9 NA NA NA
THR D:284 D:284 26.0 0.186 -137.9 23.2 NA NA NA
THR E:284 E:284 24.0 0.171 -142.9 3.2 NA NA NA
THR F:284 F:284 22.0 0.157 -139.9 20.9 NA NA NA
THR G:284 G:284 23.0 0.164 -137.9 12.5 NA NA NA
THR H:284 H:284 22.0 0.157 -142.0 4.6 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 THR A:284 A:284 23.0 0.164 -132.2 15.0 23.0 0.164 0.0 SO4
FAD
HOH
 3.354
6.189
2.650
 O
CA
OG1
 O3
N7A
O
THR B:284 B:284 24.0 0.171 -138.3 15.2 24.0 0.171 0.0 SO4
FAD
HOH
 3.745
6.156
2.440
 O
CA
OG1
 O3
N7A
O
THR C:284 C:284 27.0 0.193 -138.1 19.8 NA NA NA
THR D:284 D:284 24.0 0.171 -130.4 19.1 NA NA NA
THR E:284 E:284 25.0 0.179 -136.5 10.5 NA NA NA
THR F:284 F:284 22.0 0.157 -135.5 19.7 NA NA NA
THR G:284 G:284 24.0 0.171 -136.7 15.0 NA NA NA
THR H:284 H:284 22.0 0.157 -137.3 15.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 THR A:284 A:284 27.0 0.193 -142.1 17.3 27.0 0.193 0.0 SO4
FAD
HOH
 3.710
6.123
2.540
 O
CA
OG1
 O3
N7A
O
THR B:284 B:284 26.0 0.186 -132.7 12.9 26.0 0.186 0.0 SO4
FAD
HOH
 3.518
6.217
2.575
 O
CA
OG1
 O2
N7A
O
THR C:284 C:284 23.0 0.164 -139.8 17.1 NA NA NA
THR D:284 D:284 23.0 0.164 -140.1 23.8 NA NA NA
THR E:284 E:284 24.0 0.171 -135.9 3.6 NA NA NA
THR F:284 F:284 25.0 0.179 -140.9 21.0 NA NA NA
THR G:284 G:284 24.0 0.171 -140.5 17.2 NA NA NA
THR H:284 H:284 25.0 0.179 -139.5 17.3 NA NA NA
THR I:284 I:284 22.0 0.157 -142.1 22.6 NA NA NA
THR J:284 J:284 23.0 0.164 -141.5 22.7 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 THR A:305 A:284 27.0 0.193 -137.9 17.1 27.0 0.193 0.0 FAD
TRS
HOH
 5.172
7.549
2.503
 HA
N
HG23
 H61A
O3
O
THR B:305 B:284 29.0 0.207 -136.0 19.5 29.0 0.207 0.0 FAD
HOH
 5.366
2.687
 HA
HG1
 N7A
O
THR C:305 C:284 28.0 0.2 -135.7 19.4 NA NA NA
THR D:305 D:284 20.0 0.143 -134.8 21.1 NA NA NA
THR E:305 E:284 27.0 0.193 -135.3 16.5 NA NA NA
THR F:305 F:284 20.0 0.143 -135.6 21.0 NA NA NA
THR G:305 G:284 29.0 0.207 -137.3 19.0 NA NA NA
THR H:305 H:284 29.0 0.207 -136.1 15.5 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:306 A:284 26.0 0.186 -135.1 19.8 26.0 0.186 0.0 FAD
SO4
HOH
 5.311
3.360
2.009
 HA
O
H
 H61A
O3
O
THR B:306 B:284 27.0 0.193 -135.1 20.5 27.0 0.193 0.0 FAD
SO4
HOH
 5.332
3.458
1.980
 HA
O
H
 H61A
O1
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 THR A:306 A:284 28.0 0.2 -132.7 20.7 28.0 0.2 0.0 FAD
GOL
HOH
 6.348
2.647
2.632
 CA
O
OG1
 N7A
O1
O
THR B:306 B:284 30.0 0.214 -133.6 16.1 30.0 0.214 0.0 FAD
HOH
 6.162
2.721
 CA
OG1
 N7A
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 THR A:306 A:284 28.0 0.2 -131.9 18.5 28.0 0.2 0.0 FAD
SO4
HOH
 6.203
3.157
2.629
 CA
O
OG1
 N7A
O4
O
THR B:306 B:284 26.0 0.186 -129.2 21.8 26.0 0.186 0.0 FAD
SO4
HOH
 6.267
3.477
2.774
 CA
O
OG1
 N7A
O1
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:306 A:284 26.0 0.186 -136.2 20.4 26.0 0.186 0.0 FAD
SO4
BTB
HOH
 5.408
3.325
6.437
1.996
 HA
O
N
HG1
 H61A
O3
H62
O
THR B:306 B:284 26.0 0.186 -136.8 20.4 26.0 0.186 0.0 FAD
SO4
BTB
HOH
 5.441
3.302
6.552
1.977
 HA
O
N
H
 N7A
O2
H82
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:306 A:284 27.0 0.193 -136.8 18.1 27.0 0.193 0.0 FAD
SO4
BTB
HOH
 5.402
3.289
6.884
2.092
 HA
O
N
HG1
 H62A
O3
HO8
O
THR B:306 B:284 27.0 0.193 -139.2 18.1 27.0 0.193 0.0 FAD
SO4
BTB
HOH
 5.140
3.267
6.460
2.024
 HA
O
N
HG1
 H61A
O1
H82
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:306 A:284 26.0 0.186 -135.0 18.5 26.0 0.186 0.0 FAD
SO4
SO4
HOH
 5.394
3.295
9.839
1.977
 HA
O
H
HG1
 N7A
O3
O4
O
THR B:306 B:284 27.0 0.193 -133.6 18.7 27.0 0.193 0.0 FAD
SO4
HOH
 5.448
3.380
2.116
 HA
O
H
 N7A
O2
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 THR A:306 A:284 24.0 0.171 -138.8 21.4 24.0 0.171 0.0 FAD
SO4
HOH
 5.352
3.640
1.891
 HA
O
HG1
 H61A
O4
O
THR B:306 B:284 27.0 0.193 -136.2 19.0 27.0 0.193 0.0 FAD
HOH
 5.448
9.643
 HA
HG21
 H61A
O
THR C:306 C:284 25.0 0.179 -137.1 22.3 NA NA NA
THR D:306 D:284 23.0 0.164 -138.8 19.2 NA NA NA
THR E:306 E:284 26.0 0.186 -139.9 23.2 NA NA NA
THR F:306 F:284 27.0 0.193 -139.9 21.9 NA NA NA
THR G:306 G:284 26.0 0.186 -138.6 20.7 NA NA NA
THR H:306 H:284 26.0 0.186 -139.2 23.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 THR A:319 A:319 28.0 0.2 -130.9 7.8