Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107557346 | . | G | A | CCDS5749.1:NM_000108.3:c.983gGa>gAa_NP_000099.2:p.328G>E | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
---|---|---|---|---|---|---|---|
|
|
|
|
PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLY | A:314 | A:293 | 29.0 | 0.387 | T | 73.7 | 16.1 | 29.0 | 0.387 | 0.0 |
HOH |
6.813 |
O |
O |
||
GLY | B:314 | B:293 | 35.0 | 0.467 | T | 96.0 | 27.4 | 35.0 | 0.467 | 0.0 | |||||||||||||
GLY | C:314 | C:293 | 33.0 | 0.44 | T | 61.3 | 38.3 | NA | NA | NA | |||||||||||||
GLY | D:314 | D:293 | 38.0 | 0.507 | T | 81.8 | 16.6 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLY | A:293 | A:293 | 43.0 | 0.573 | T | 77.0 | 24.9 | 43.0 | 0.573 | 0.0 |
HOH |
9.997 |
O |
O |
||
GLY | B:293 | B:293 | 49.0 | 0.653 | T | 71.0 | 23.5 | 49.0 | 0.653 | 0.0 |
HOH |
4.817 |
O |
O |
|||||||||
GLY | C:293 | C:293 | 44.0 | 0.587 | T | 80.5 | 2.2 | NA | NA | NA | |||||||||||||
GLY | D:293 | D:293 | 48.0 | 0.64 | T | 73.0 | 12.6 | NA | NA | NA | |||||||||||||
GLY | E:293 | E:293 | 35.0 | 0.467 | T | 105.4 | 38.1 | NA | NA | NA | |||||||||||||
GLY | F:293 | F:293 | 49.0 | 0.653 | T | 69.8 | 31.3 | NA | NA | NA | |||||||||||||
GLY | G:293 | G:293 | 39.0 | 0.52 | T | 102.9 | 3.9 | NA | NA | NA | |||||||||||||
GLY | H:293 | H:293 | 41.0 | 0.547 | T | 87.3 | 12.6 | NA | NA | NA | |||||||||||||
GLY | I:293 | I:293 | 65.0 | 0.867 | S | 42.2 | 27.8 | NA | NA | NA | |||||||||||||
GLY | J:293 | J:293 | 51.0 | 0.68 | T | 82.0 | 13.8 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 31.0 | 0.413 | T | 89.2 | 11.7 | 31.0 | 0.413 | 0.0 |
SO4 HOH |
7.053 4.712 |
H O |
O1 O |
||
GLY | B:315 | B:293 | 32.0 | 0.427 | T | 87.7 | 11.6 | 32.0 | 0.427 | 0.0 |
SO4 HOH |
7.099 5.243 |
H O |
O4 O |
|||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 29.0 | 0.387 | T | 83.2 | 13.7 | 29.0 | 0.387 | 0.0 |
SO4 HOH |
7.065 4.640 |
H O |
O1 O |
||
GLY | B:315 | B:293 | 24.0 | 0.32 | T | 82.0 | 13.6 | 24.0 | 0.32 | 0.0 |
SO4 HOH |
6.913 4.841 |
H O |
O3 O |
|||||||||
1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLY | A:293 | A:293 | 25.0 | 0.333 | T | 103.1 | 12.2 | 25.0 | 0.333 | 0.0 |
SO4 HOH |
7.965 5.912 |
N C |
O1 O |
||
GLY | B:293 | B:293 | 39.0 | 0.52 | T | 101.7 | 2.7 | 39.0 | 0.52 | 0.0 | |||||||||||||
GLY | C:293 | C:293 | 44.0 | 0.587 | T | 105.5 | 29.8 | NA | NA | NA | |||||||||||||
GLY | D:293 | D:293 | 25.0 | 0.333 | T | 101.9 | 8.4 | NA | NA | NA | |||||||||||||
GLY | E:293 | E:293 | 42.0 | 0.56 | T | 98.9 | 16.7 | NA | NA | NA | |||||||||||||
GLY | F:293 | F:293 | 30.0 | 0.4 | T | 89.2 | 20.5 | NA | NA | NA | |||||||||||||
GLY | G:293 | G:293 | 31.0 | 0.413 | T | 93.0 | 20.2 | NA | NA | NA | |||||||||||||
GLY | H:293 | H:293 | 45.0 | 0.6 | T | 99.1 | 9.7 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLY | A:293 | A:293 | 27.0 | 0.36 | T | 89.1 | 14.7 | 27.0 | 0.36 | 0.0 |
SO4 HOH |
7.830 4.934 |
N O |
O1 O |
||
GLY | B:293 | B:293 | 39.0 | 0.52 | T | 103.4 | -1.7 | 39.0 | 0.52 | 0.0 |
SO4 |
8.014 |
N |
O4 |
|||||||||
GLY | C:293 | C:293 | 40.0 | 0.533 | T | 97.0 | 9.0 | NA | NA | NA | |||||||||||||
GLY | D:293 | D:293 | 27.0 | 0.36 | T | 92.5 | 12.1 | NA | NA | NA | |||||||||||||
GLY | E:293 | E:293 | 39.0 | 0.52 | T | 108.8 | 0.3 | NA | NA | NA | |||||||||||||
GLY | F:293 | F:293 | 31.0 | 0.413 | T | 87.9 | 16.2 | NA | NA | NA | |||||||||||||
GLY | G:293 | G:293 | 27.0 | 0.36 | T | 89.6 | 17.8 | NA | NA | NA | |||||||||||||
GLY | H:293 | H:293 | 39.0 | 0.52 | T | 90.7 | 9.5 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLY | A:293 | A:293 | 31.0 | 0.413 | T | 80.8 | 15.6 | 31.0 | 0.413 | 0.0 |
SO4 HOH |
7.273 4.674 |
N O |
O1 O |
||
GLY | B:293 | B:293 | 28.0 | 0.373 | T | 92.5 | 15.9 | 28.0 | 0.373 | 0.0 |
SO4 |
7.575 |
N |
O1 |
|||||||||
GLY | C:293 | C:293 | 19.0 | 0.253 | T | 87.3 | 9.5 | NA | NA | NA | |||||||||||||
GLY | D:293 | D:293 | 36.0 | 0.48 | T | 91.8 | 9.5 | NA | NA | NA | |||||||||||||
GLY | E:293 | E:293 | 45.0 | 0.6 | T | 88.9 | 11.7 | NA | NA | NA | |||||||||||||
GLY | F:293 | F:293 | 36.0 | 0.48 | T | 90.0 | 7.7 | NA | NA | NA | |||||||||||||
GLY | G:293 | G:293 | 35.0 | 0.467 | T | 87.5 | 33.2 | NA | NA | NA | |||||||||||||
GLY | H:293 | H:293 | 27.0 | 0.36 | T | 85.6 | 13.1 | NA | NA | NA | |||||||||||||
GLY | I:293 | I:293 | 35.0 | 0.467 | T | 100.1 | 7.8 | NA | NA | NA | |||||||||||||
GLY | J:293 | J:293 | 30.0 | 0.4 | T | 86.6 | 15.4 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLY | A:314 | A:293 | 44.0 | 0.587 | T | 81.7 | 15.6 | 44.0 | 0.587 | 0.0 |
HOH |
5.179 |
O |
O |
||
GLY | B:314 | B:293 | 27.0 | 0.36 | T | 83.4 | 12.9 | 27.0 | 0.36 | 0.0 |
HOH |
4.604 |
O |
O |
|||||||||
GLY | C:314 | C:293 | 32.0 | 0.427 | T | 84.3 | 16.3 | NA | NA | NA | |||||||||||||
GLY | D:314 | D:293 | 51.0 | 0.68 | T | 85.2 | 17.2 | NA | NA | NA | |||||||||||||
GLY | E:314 | E:293 | 41.0 | 0.547 | T | 84.6 | 15.1 | NA | NA | NA | |||||||||||||
GLY | F:314 | F:293 | 31.0 | 0.413 | T | 84.1 | 14.9 | NA | NA | NA | |||||||||||||
GLY | G:314 | G:293 | 40.0 | 0.533 | T | 86.3 | 16.7 | NA | NA | NA | |||||||||||||
GLY | H:314 | H:293 | 49.0 | 0.653 | T | 85.3 | 13.9 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 33.0 | 0.44 | T | 85.0 | 13.3 | 33.0 | 0.44 | 0.0 |
SO4 HOH |
6.949 4.794 |
H O |
O2 O |
||
GLY | B:315 | B:293 | 29.0 | 0.387 | T | 84.0 | 12.6 | 29.0 | 0.387 | 0.0 |
SO4 HOH |
6.599 5.083 |
H O |
O3 O |
|||||||||
5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLY | A:315 | A:293 | 30.0 | 0.4 | T | 88.4 | 13.1 | 30.0 | 0.4 | 0.0 |
GOL HOH |
7.351 3.535 |
N CA |
O3 O |
||
GLY | B:315 | B:293 | 32.0 | 0.427 | T | 70.0 | 44.9 | 32.0 | 0.427 | 0.0 |
HOH |
5.266 |
O |
O |
|||||||||
6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLY | A:315 | A:293 | 34.0 | 0.453 | T | 85.8 | 15.6 | 34.0 | 0.453 | 0.0 |
SO4 HOH |
7.688 3.702 |
N CA |
O2 O |
||
GLY | B:315 | B:293 | 29.0 | 0.387 | T | 84.3 | 15.2 | 29.0 | 0.387 | 0.0 |
SO4 HOH |
7.682 3.470 |
N CA |
O4 O |
|||||||||
6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 32.0 | 0.427 | T | 86.9 | 14.3 | 32.0 | 0.427 | 0.0 |
SO4 HOH |
7.103 2.642 |
H O |
O1 O |
||
GLY | B:315 | B:293 | 31.0 | 0.413 | T | 85.9 | 14.8 | 31.0 | 0.413 | 0.0 |
SO4 HOH |
7.052 4.987 |
H O |
O3 O |
|||||||||
6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 32.0 | 0.427 | T | 85.3 | 14.7 | 32.0 | 0.427 | 0.0 |
SO4 HOH |
6.994 4.659 |
H O |
O1 O |
||
GLY | B:315 | B:293 | 31.0 | 0.413 | T | 85.1 | 14.2 | 31.0 | 0.413 | 0.0 |
SO4 HOH |
6.960 4.869 |
H O |
O3 O |
|||||||||
6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 29.0 | 0.387 | T | 86.9 | 14.2 | 29.0 | 0.387 | 0.0 |
SO4 HOH |
7.036 4.943 |
H O |
O1 O |
||
GLY | B:315 | B:293 | 31.0 | 0.413 | T | 84.6 | 12.5 | 31.0 | 0.413 | 0.0 |
SO4 HOH |
6.751 4.975 |
H O |
O3 O |
|||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLY | A:315 | A:293 | 35.0 | 0.467 | T | 91.1 | 11.6 | 35.0 | 0.467 | 0.0 |
SO4 HOH |
7.200 4.680 |
H O |
O3 O |
||
GLY | B:315 | B:293 | 43.0 | 0.573 | T | 90.8 | 12.0 | 43.0 | 0.573 | 0.0 |
HOH |
6.668 |
O |
O |
|||||||||
GLY | C:315 | C:293 | 38.0 | 0.507 | T | 91.1 | 11.8 | NA | NA | NA | |||||||||||||
GLY | D:315 | D:293 | 38.0 | 0.507 | T | 93.2 | 10.9 | NA | NA | NA | |||||||||||||
GLY | E:315 | E:293 | 37.0 | 0.493 | T | 92.9 | 13.8 | NA | NA | NA | |||||||||||||
GLY | F:315 | F:293 | 39.0 | 0.52 | T | 95.9 | 15.2 | NA | NA | NA | |||||||||||||
GLY | G:315 | G:293 | 35.0 | 0.467 | T | 93.1 | 12.3 | NA | NA | NA | |||||||||||||
GLY | H:315 | H:293 | 29.0 | 0.387 | T | 93.8 | 14.0 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLY | A:328 | A:328 | 31.0 | 0.413 | T | 68.5 | 21.9 |