Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107557351 | . | G | A | CCDS5749.1:NM_000108.3:c.988Gaa>Aaa_NP_000099.2:p.330E>K | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLU | A:316 | A:295 | 130.0 | 0.684 | -90.7 | 152.3 | 130.0 | 0.684 | 0.0 |
HOH |
4.949 |
O |
O |
|||
GLU | B:316 | B:295 | 139.0 | 0.732 | -92.7 | 134.0 | 139.0 | 0.732 | 0.0 | ||||||||||||||
GLU | C:316 | C:295 | 148.0 | 0.779 | -92.6 | 142.7 | NA | NA | NA | ||||||||||||||
GLU | D:316 | D:295 | 139.0 | 0.732 | -81.5 | 151.9 | NA | NA | NA | ||||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLU | A:295 | A:295 | 149.0 | 0.784 | -79.1 | 148.2 | 149.0 | 0.784 | 0.0 |
HOH |
8.342 |
O |
O |
|||
GLU | B:295 | B:295 | 147.0 | 0.774 | -72.2 | 146.4 | 147.0 | 0.774 | 0.0 |
HOH |
2.957 |
O |
O |
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GLU | C:295 | C:295 | 142.0 | 0.747 | -91.7 | 142.7 | NA | NA | NA | ||||||||||||||
GLU | D:295 | D:295 | 156.0 | 0.821 | -111.1 | 130.9 | NA | NA | NA | ||||||||||||||
GLU | E:295 | E:295 | 136.0 | 0.716 | -91.9 | 150.1 | NA | NA | NA | ||||||||||||||
GLU | F:295 | F:295 | 154.0 | 0.811 | -74.7 | 144.6 | NA | NA | NA | ||||||||||||||
GLU | G:295 | G:295 | 144.0 | 0.758 | -83.2 | 140.3 | NA | NA | NA | ||||||||||||||
GLU | H:295 | H:295 | 152.0 | 0.8 | -71.5 | 145.4 | NA | NA | NA | ||||||||||||||
GLU | I:295 | I:295 | 126.0 | 0.663 | -67.4 | -172.9 | NA | NA | NA | ||||||||||||||
GLU | J:295 | J:295 | 153.0 | 0.805 | -109.6 | 121.9 | NA | NA | NA | ||||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 141.0 | 0.742 | -87.9 | 149.4 | 141.0 | 0.742 | 0.0 |
SO4 HOH |
7.478 2.520 |
HA H |
O1 O |
|||
GLU | B:317 | B:295 | 145.0 | 0.763 | -88.3 | 147.5 | 145.0 | 0.763 | 0.0 |
SO4 HOH |
7.512 2.629 |
HA HA |
O4 O |
||||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 153.0 | 0.805 | -83.8 | 147.7 | 153.0 | 0.805 | 0.0 |
SO4 HOH |
7.538 2.537 |
HA H |
O1 O |
|||
GLU | B:317 | B:295 | 158.0 | 0.832 | -83.1 | 145.0 | 158.0 | 0.832 | 0.0 |
SO4 HOH |
7.556 2.681 |
HA O |
O3 O |
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1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLU | A:295 | A:295 | 146.0 | 0.768 | -81.3 | 142.8 | 146.0 | 0.768 | 0.0 |
SO4 HOH |
8.219 3.833 |
CA CA |
O1 O |
|||
GLU | B:295 | B:295 | 145.0 | 0.763 | -84.7 | 129.7 | 145.0 | 0.763 | 0.0 |
HOH |
8.768 |
C |
O |
||||||||||
GLU | C:295 | C:295 | 141.0 | 0.742 | -83.6 | 133.0 | NA | NA | NA | ||||||||||||||
GLU | D:295 | D:295 | 148.0 | 0.779 | -78.6 | 139.9 | NA | NA | NA | ||||||||||||||
GLU | E:295 | E:295 | 134.0 | 0.705 | -79.8 | 146.8 | NA | NA | NA | ||||||||||||||
GLU | F:295 | F:295 | 144.0 | 0.758 | -77.3 | 142.0 | NA | NA | NA | ||||||||||||||
GLU | G:295 | G:295 | 149.0 | 0.784 | -77.4 | 145.7 | NA | NA | NA | ||||||||||||||
GLU | H:295 | H:295 | 138.0 | 0.726 | -79.2 | 143.3 | NA | NA | NA | ||||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLU | A:295 | A:295 | 143.0 | 0.753 | -90.5 | 142.3 | 143.0 | 0.753 | 0.0 |
SO4 HOH |
8.268 2.657 |
CA O |
O1 O |
|||
GLU | B:295 | B:295 | 152.0 | 0.8 | -90.4 | 130.1 | 152.0 | 0.8 | 0.0 |
SO4 HOH |
8.534 7.899 |
CA O |
O2 O |
||||||||||
GLU | C:295 | C:295 | 137.0 | 0.721 | -93.6 | 144.4 | NA | NA | NA | ||||||||||||||
GLU | D:295 | D:295 | 139.0 | 0.732 | -93.5 | 141.9 | NA | NA | NA | ||||||||||||||
GLU | E:295 | E:295 | 148.0 | 0.779 | -98.2 | 133.9 | NA | NA | NA | ||||||||||||||
GLU | F:295 | F:295 | 150.0 | 0.789 | -86.3 | 139.9 | NA | NA | NA | ||||||||||||||
GLU | G:295 | G:295 | 147.0 | 0.774 | -83.0 | 142.3 | NA | NA | NA | ||||||||||||||
GLU | H:295 | H:295 | 146.0 | 0.768 | -80.5 | 137.2 | NA | NA | NA | ||||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLU | A:295 | A:295 | 135.0 | 0.711 | -100.9 | 138.1 | 135.0 | 0.711 | 0.0 |
SO4 HOH |
8.868 2.981 |
N O |
O1 O |
|||
GLU | B:295 | B:295 | 145.0 | 0.763 | -89.5 | 113.1 | 145.0 | 0.763 | 0.0 |
SO4 HOH |
8.212 8.543 |
N C |
O1 O |
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GLU | C:295 | C:295 | 121.0 | 0.637 | -88.2 | 146.4 | NA | NA | NA | ||||||||||||||
GLU | D:295 | D:295 | 121.0 | 0.637 | -77.7 | 143.4 | NA | NA | NA | ||||||||||||||
GLU | E:295 | E:295 | 156.0 | 0.821 | -92.9 | 136.5 | NA | NA | NA | ||||||||||||||
GLU | F:295 | F:295 | 121.0 | 0.637 | -82.9 | 143.9 | NA | NA | NA | ||||||||||||||
GLU | G:295 | G:295 | 165.0 | 0.868 | -93.0 | 140.4 | NA | NA | NA | ||||||||||||||
GLU | H:295 | H:295 | 157.0 | 0.826 | -84.8 | 147.0 | NA | NA | NA | ||||||||||||||
GLU | I:295 | I:295 | 144.0 | 0.758 | -100.1 | 150.0 | NA | NA | NA | ||||||||||||||
GLU | J:295 | J:295 | 153.0 | 0.805 | -78.9 | 143.0 | NA | NA | NA | ||||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLU | A:316 | A:295 | 160.0 | 0.842 | -95.2 | 131.6 | 160.0 | 0.842 | 0.0 |
HOH |
2.667 |
H |
O |
|||
GLU | B:316 | B:295 | 145.0 | 0.763 | -101.5 | 137.7 | 145.0 | 0.763 | 0.0 |
HOH |
2.513 |
H |
O |
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GLU | C:316 | C:295 | 153.0 | 0.805 | -95.8 | 130.9 | NA | NA | NA | ||||||||||||||
GLU | D:316 | D:295 | 170.0 | 0.895 | -92.1 | 131.5 | NA | NA | NA | ||||||||||||||
GLU | E:316 | E:295 | 161.0 | 0.847 | -96.8 | 131.4 | NA | NA | NA | ||||||||||||||
GLU | F:316 | F:295 | 144.0 | 0.758 | -98.7 | 133.9 | NA | NA | NA | ||||||||||||||
GLU | G:316 | G:295 | 143.0 | 0.753 | -98.8 | 132.9 | NA | NA | NA | ||||||||||||||
GLU | H:316 | H:295 | 142.0 | 0.747 | -94.7 | 133.3 | NA | NA | NA | ||||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 152.0 | 0.8 | -86.7 | 144.5 | 152.0 | 0.8 | 0.0 |
SO4 HOH |
7.554 2.545 |
HA H |
O2 O |
|||
GLU | B:317 | B:295 | 162.0 | 0.853 | -85.4 | 143.0 | 162.0 | 0.853 | 0.0 |
SO4 HOH |
7.731 2.479 |
HA O |
O3 O |
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5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLU | A:317 | A:295 | 146.0 | 0.768 | -88.7 | 144.1 | 146.0 | 0.768 | 0.0 |
GOL HOH |
8.040 2.671 |
N O |
O3 O |
|||
GLU | B:317 | B:295 | 152.0 | 0.8 | -85.7 | 141.8 | 152.0 | 0.8 | 0.0 |
HOH |
2.572 |
O |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLU | A:317 | A:295 | 140.0 | 0.737 | -85.7 | 152.3 | 140.0 | 0.737 | 0.0 |
SO4 HOH |
8.345 2.729 |
CA O |
O2 O |
|||
GLU | B:317 | B:295 | 153.0 | 0.805 | -86.4 | 141.8 | 153.0 | 0.805 | 0.0 |
SO4 HOH |
8.411 2.674 |
N O |
O4 O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 153.0 | 0.805 | -86.1 | 151.3 | 153.0 | 0.805 | 0.0 |
SO4 HOH |
7.585 2.626 |
HA H |
O1 O |
|||
GLU | B:317 | B:295 | 155.0 | 0.816 | -86.0 | 148.4 | 155.0 | 0.816 | 0.0 |
SO4 HOH |
7.616 2.662 |
HA O |
O3 O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 147.0 | 0.774 | -86.2 | 148.3 | 147.0 | 0.774 | 0.0 |
SO4 HOH |
7.560 2.500 |
HA H |
O1 O |
|||
GLU | B:317 | B:295 | 145.0 | 0.763 | -86.1 | 146.6 | 145.0 | 0.763 | 0.0 |
SO4 HOH |
7.557 2.712 |
HA H |
O3 O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 149.0 | 0.784 | -84.1 | 149.4 | 149.0 | 0.784 | 0.0 |
SO4 HOH |
7.516 2.693 |
HA O |
O1 O |
|||
GLU | B:317 | B:295 | 143.0 | 0.753 | -83.5 | 144.2 | 143.0 | 0.753 | 0.0 |
SO4 HOH |
7.468 2.775 |
HA HA |
O3 O |
||||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:317 | A:295 | 165.0 | 0.868 | -80.9 | 143.0 | 165.0 | 0.868 | 0.0 |
SO4 HOH |
7.564 2.618 |
HA H |
O3 O |
|||
GLU | B:317 | B:295 | 141.0 | 0.742 | -80.2 | 143.8 | 141.0 | 0.742 | 0.0 |
HOH |
5.479 |
O |
O |
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GLU | C:317 | C:295 | 150.0 | 0.789 | -81.1 | 145.6 | NA | NA | NA | ||||||||||||||
GLU | D:317 | D:295 | 136.0 | 0.716 | -80.1 | 144.9 | NA | NA | NA | ||||||||||||||
GLU | E:317 | E:295 | 144.0 | 0.758 | -77.5 | 140.2 | NA | NA | NA | ||||||||||||||
GLU | F:317 | F:295 | 158.0 | 0.832 | -80.3 | 140.5 | NA | NA | NA | ||||||||||||||
GLU | G:317 | G:295 | 161.0 | 0.847 | -78.0 | 146.8 | NA | NA | NA | ||||||||||||||
GLU | H:317 | H:295 | 148.0 | 0.779 | -80.3 | 145.1 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLU | A:330 | A:330 | 148.0 | 0.779 | -73.3 | 145.0 |