Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107557399 | . | A | C | CCDS5749.1:NM_000108.3:c.1036Aaa>Caa_NP_000099.2:p.346K>Q | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | LYS | A:332 | A:311 | 155.0 | 0.775 | S | -50.3 | -23.0 | 155.0 | 0.775 | 0.0 |
HOH |
2.690 |
N |
O |
||
LYS | B:332 | B:311 | 174.0 | 0.87 | S | -55.3 | -35.7 | 174.0 | 0.87 | 0.0 | |||||||||||||
LYS | C:332 | C:311 | 153.0 | 0.765 | S | -53.3 | -36.2 | NA | NA | NA | |||||||||||||
LYS | D:332 | D:311 | 122.0 | 0.61 | S | -51.0 | -50.8 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | LYS | A:311 | A:311 | 169.0 | 0.845 | S | -56.4 | -33.9 | 169.0 | 0.845 | 0.0 |
HOH |
4.105 |
CD |
O |
||
LYS | B:311 | B:311 | 181.0 | 0.905 | S | -57.9 | -25.3 | 181.0 | 0.905 | 0.0 |
HOH |
3.567 |
CG |
O |
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LYS | C:311 | C:311 | 165.0 | 0.825 | S | -49.2 | -41.9 | NA | NA | NA | |||||||||||||
LYS | D:311 | D:311 | 147.0 | 0.735 | S | -43.6 | -38.4 | NA | NA | NA | |||||||||||||
LYS | E:311 | E:311 | 181.0 | 0.905 | S | -65.4 | -29.3 | NA | NA | NA | |||||||||||||
LYS | F:311 | F:311 | 188.0 | 0.94 | S | -49.2 | -43.0 | NA | NA | NA | |||||||||||||
LYS | G:311 | G:311 | 149.0 | 0.745 | S | -71.2 | -10.4 | NA | NA | NA | |||||||||||||
LYS | H:311 | H:311 | 179.0 | 0.895 | S | -42.0 | -33.2 | NA | NA | NA | |||||||||||||
LYS | I:311 | I:311 | 161.0 | 0.805 | S | -62.3 | -5.6 | NA | NA | NA | |||||||||||||
LYS | J:311 | J:311 | 172.0 | 0.86 | S | -65.3 | -29.6 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 138.0 | 0.69 | S | -63.1 | -18.1 | 138.0 | 0.69 | 0.0 |
SO4 HOH |
8.077 1.932 |
O H |
O1 O |
||
LYS | B:333 | B:311 | 119.0 | 0.595 | S | -61.7 | -19.8 | 119.0 | 0.595 | 0.0 |
HOH |
2.252 |
H |
O |
|||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 152.0 | 0.76 | S | -59.6 | -22.0 | 152.0 | 0.76 | 0.0 |
HOH |
2.084 |
H |
O |
||
LYS | B:333 | B:311 | 135.0 | 0.675 | S | -60.2 | -26.8 | 135.0 | 0.675 | 0.0 |
HOH |
2.128 |
H |
O |
|||||||||
1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | LYS | A:311 | A:311 | 149.0 | 0.745 | S | -55.3 | -31.0 | 149.0 | 0.745 | 0.0 |
HOH |
2.765 |
N |
O |
||
LYS | B:311 | B:311 | 153.0 | 0.765 | S | -63.3 | -46.5 | 153.0 | 0.765 | 0.0 | |||||||||||||
LYS | C:311 | C:311 | 148.0 | 0.74 | S | -64.9 | -33.9 | NA | NA | NA | |||||||||||||
LYS | D:311 | D:311 | 148.0 | 0.74 | S | -54.7 | -32.7 | NA | NA | NA | |||||||||||||
LYS | E:311 | E:311 | 157.0 | 0.785 | S | -62.7 | -9.8 | NA | NA | NA | |||||||||||||
LYS | F:311 | F:311 | 145.0 | 0.725 | S | -53.0 | -38.4 | NA | NA | NA | |||||||||||||
LYS | G:311 | G:311 | 154.0 | 0.77 | S | -52.4 | -36.1 | NA | NA | NA | |||||||||||||
LYS | H:311 | H:311 | 145.0 | 0.725 | S | -60.4 | -28.5 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | LYS | A:311 | A:311 | 144.0 | 0.72 | S | -54.4 | -34.1 | 144.0 | 0.72 | 0.0 |
HOH |
2.809 |
N |
O |
||
LYS | B:311 | B:311 | 150.0 | 0.75 | S | -62.8 | -45.2 | 150.0 | 0.75 | 0.0 | |||||||||||||
LYS | C:311 | C:311 | 150.0 | 0.75 | S | -67.7 | -31.6 | NA | NA | NA | |||||||||||||
LYS | D:311 | D:311 | 146.0 | 0.73 | S | -53.8 | -28.0 | NA | NA | NA | |||||||||||||
LYS | E:311 | E:311 | 149.0 | 0.745 | S | -59.7 | -26.5 | NA | NA | NA | |||||||||||||
LYS | F:311 | F:311 | 144.0 | 0.72 | S | -52.3 | -27.2 | NA | NA | NA | |||||||||||||
LYS | G:311 | G:311 | 149.0 | 0.745 | S | -51.7 | -34.3 | NA | NA | NA | |||||||||||||
LYS | H:311 | H:311 | 144.0 | 0.72 | S | -57.1 | -27.9 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | LYS | A:311 | A:311 | 145.0 | 0.725 | S | -55.5 | -50.1 | 145.0 | 0.725 | 0.0 |
HOH |
3.262 |
CD |
O |
||
LYS | B:311 | B:311 | 128.0 | 0.64 | S | -72.3 | -56.6 | 128.0 | 0.64 | 0.0 | |||||||||||||
LYS | C:311 | C:311 | 152.0 | 0.76 | S | -58.0 | -33.0 | NA | NA | NA | |||||||||||||
LYS | D:311 | D:311 | 152.0 | 0.76 | S | -66.6 | -15.2 | NA | NA | NA | |||||||||||||
LYS | E:311 | E:311 | 175.0 | 0.875 | S | -62.2 | -20.8 | NA | NA | NA | |||||||||||||
LYS | F:311 | F:311 | 129.0 | 0.645 | S | -55.9 | -21.6 | NA | NA | NA | |||||||||||||
LYS | G:311 | G:311 | 169.0 | 0.845 | S | -54.0 | -37.5 | NA | NA | NA | |||||||||||||
LYS | H:311 | H:311 | 146.0 | 0.73 | S | -65.1 | -21.6 | NA | NA | NA | |||||||||||||
LYS | I:311 | I:311 | 122.0 | 0.61 | S | -54.8 | -31.3 | NA | NA | NA | |||||||||||||
LYS | J:311 | J:311 | 135.0 | 0.675 | S | -62.9 | -13.9 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | LYS | A:332 | A:311 | 174.0 | 0.87 | S | -58.4 | -30.7 | 174.0 | 0.87 | 0.0 |
HOH |
3.520 |
HD2 |
O |
||
LYS | B:332 | B:311 | 139.0 | 0.695 | S | -54.1 | -34.9 | 139.0 | 0.695 | 0.0 |
HOH |
2.662 |
HD3 |
O |
|||||||||
LYS | C:332 | C:311 | 130.0 | 0.65 | S | -54.4 | -34.2 | NA | NA | NA | |||||||||||||
LYS | D:332 | D:311 | 163.0 | 0.815 | S | -59.4 | -31.3 | NA | NA | NA | |||||||||||||
LYS | E:332 | E:311 | 179.0 | 0.895 | S | -57.7 | -28.1 | NA | NA | NA | |||||||||||||
LYS | F:332 | F:311 | 125.0 | 0.625 | S | -56.5 | -31.5 | NA | NA | NA | |||||||||||||
LYS | G:332 | G:311 | 115.0 | 0.575 | S | -55.7 | -32.5 | NA | NA | NA | |||||||||||||
LYS | H:332 | H:311 | 148.0 | 0.74 | S | -60.4 | -24.2 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 152.0 | 0.76 | S | -63.5 | -18.9 | 152.0 | 0.76 | 0.0 |
HOH |
2.255 |
H |
O |
||
LYS | B:333 | B:311 | 156.0 | 0.78 | S | -65.2 | -19.5 | 156.0 | 0.78 | 0.0 |
HOH |
3.625 |
HD2 |
O |
|||||||||
5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | LYS | A:333 | A:311 | 137.0 | 0.685 | S | -56.7 | -19.5 | 137.0 | 0.685 | 0.0 |
HOH |
2.847 |
N |
O |
||
LYS | B:333 | B:311 | 154.0 | 0.77 | S | -61.7 | -19.5 | 154.0 | 0.77 | 0.0 |
HOH |
2.887 |
N |
O |
|||||||||
6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | LYS | A:333 | A:311 | 144.0 | 0.72 | S | -45.8 | -32.4 | 144.0 | 0.72 | 0.0 |
SO4 HOH |
7.633 3.012 |
O N |
O2 O |
||
LYS | B:333 | B:311 | 153.0 | 0.765 | S | -61.2 | -18.6 | 153.0 | 0.765 | 0.0 |
HOH |
2.998 |
N |
O |
|||||||||
6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 152.0 | 0.76 | S | -63.3 | -18.8 | 152.0 | 0.76 | 0.0 |
HOH |
1.689 |
HZ3 |
O |
||
LYS | B:333 | B:311 | 149.0 | 0.745 | S | -63.2 | -17.9 | 149.0 | 0.745 | 0.0 |
HOH |
2.181 |
H |
O |
|||||||||
6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 146.0 | 0.73 | S | -59.1 | -19.5 | 146.0 | 0.73 | 0.0 |
SO4 HOH |
7.647 2.145 |
O H |
O1 O |
||
LYS | B:333 | B:311 | 149.0 | 0.745 | S | -56.8 | -20.6 | 149.0 | 0.745 | 0.0 |
HOH |
2.182 |
H |
O |
|||||||||
6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 143.0 | 0.715 | S | -62.5 | -18.5 | 143.0 | 0.715 | 0.0 |
HOH |
2.335 |
H |
O |
||
LYS | B:333 | B:311 | 138.0 | 0.69 | S | -64.6 | -16.1 | 138.0 | 0.69 | 0.0 |
HOH |
2.224 |
H |
O |
|||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | LYS | A:333 | A:311 | 145.0 | 0.725 | S | -57.1 | -28.8 | 145.0 | 0.725 | 0.0 |
HOH |
1.858 |
H |
O |
||
LYS | B:333 | B:311 | 173.0 | 0.865 | S | -59.8 | -29.4 | 173.0 | 0.865 | 0.0 |
HOH |
2.008 |
H |
O |
|||||||||
LYS | C:333 | C:311 | 151.0 | 0.755 | S | -55.1 | -34.6 | NA | NA | NA | |||||||||||||
LYS | D:333 | D:311 | 134.0 | 0.67 | S | -58.6 | -32.5 | NA | NA | NA | |||||||||||||
LYS | E:333 | E:311 | 139.0 | 0.695 | S | -58.4 | -29.5 | NA | NA | NA | |||||||||||||
LYS | F:333 | F:311 | 177.0 | 0.885 | S | -59.3 | -32.6 | NA | NA | NA | |||||||||||||
LYS | G:333 | G:311 | 163.0 | 0.815 | S | -58.1 | -29.4 | NA | NA | NA | |||||||||||||
LYS | H:333 | H:311 | 127.0 | 0.635 | S | -56.1 | -30.2 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | LYS | A:346 | A:346 | 138.0 | 0.69 | S | -59.6 | -19.1 |