Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557759 . C A CCDS5749.1:NM_000108.3:c.1088gCt>gAt_NP_000099.2:p.363A>D Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ALA A:349 A:328 24.0 0.209 H -71.5 -38.7 13.0 0.113 0.096 B:P09622:0.096
 FAD
HOH
 2.787
5.100
 N
N
 O2
O
ALA B:349 B:328 27.0 0.235 H -64.9 -45.0 15.0 0.13 0.105 A:P09622:0.104
 FAD
HOH
 2.796
4.661
 N
CB
 O2
O
ALA C:349 C:328 26.0 0.226 H -59.6 -43.3 NA NA NA
ALA D:349 D:328 25.0 0.217 H -60.5 -44.5 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ALA A:328 A:328 26.0 0.226 H -79.7 -42.1 14.0 0.122 0.104 B:P09622:0.104
 FAD
HOH
 2.969
4.491
 N
N
 O2
O
ALA B:328 B:328 26.0 0.226 H -72.1 -41.3 14.0 0.122 0.104 A:P09622:0.104
 FAD
HOH
 2.903
4.879
 N
N
 O3'
O
ALA C:328 C:328 27.0 0.235 H -63.9 -42.9 NA NA NA
ALA D:328 D:328 29.0 0.252 H -58.6 -51.5 NA NA NA
ALA E:328 E:328 32.0 0.278 H -50.5 -47.2 NA NA NA
ALA F:328 F:328 30.0 0.261 H -71.2 -43.2 NA NA NA
ALA G:328 G:328 27.0 0.235 H -60.5 -41.5 NA NA NA
ALA H:328 H:328 28.0 0.243 H -57.7 -58.0 NA NA NA
ALA I:328 I:328 23.0 0.2 H -73.3 -40.6 NA NA NA
ALA J:328 J:328 28.0 0.243 H -71.8 -38.8 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 29.0 0.252 H -59.6 -49.5 13.0 0.113 0.139 B:P09622:0.139
 FAD
HOH
 2.021
3.737
 H
HB1
 O2
O
ALA B:350 B:328 24.0 0.209 H -60.4 -48.0 13.0 0.113 0.096 A:P09622:0.096
 FAD
HOH
 2.020
3.882
 H
HB1
 O2
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 28.0 0.243 H -62.4 -47.3 13.0 0.113 0.13 B:P09622:0.13
 FAD
1PE
HOH
 2.064
9.653
3.605
 H
O
HB1
 O2
H261
O
ALA B:350 B:328 28.0 0.243 H -63.2 -48.4 13.0 0.113 0.13 A:P09622:0.13
 FAD
HOH
 2.050
5.059
 H
HA
 O2
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ALA A:328 A:328 26.0 0.226 H -58.9 -50.4 12.0 0.104 0.122 B:P09622:0.122
 FAD
HOH
 2.676
4.929
 N
N
 O2
O
ALA B:328 B:328 24.0 0.209 H -59.5 -46.8 13.0 0.113 0.096 A:P09622:0.096
 FAD
HOH
 2.871
5.106
 N
N
 O2
O
ALA C:328 C:328 24.0 0.209 H -55.4 -54.9 NA NA NA
ALA D:328 D:328 23.0 0.2 H -72.1 -43.4 NA NA NA
ALA E:328 E:328 24.0 0.209 H -67.1 -47.3 NA NA NA
ALA F:328 F:328 22.0 0.191 H -71.2 -44.1 NA NA NA
ALA G:328 G:328 25.0 0.217 H -65.3 -52.2 NA NA NA
ALA H:328 H:328 23.0 0.2 H -65.0 -46.9 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ALA A:328 A:328 23.0 0.2 H -59.9 -46.3 13.0 0.113 0.087 B:P09622:0.087
 FAD
NAI
HOH
 2.816
6.508
4.426
 N
N
O
 O2
O7N
O
ALA B:328 B:328 24.0 0.209 H -67.1 -46.0 14.0 0.122 0.087 A:P09622:0.087
 FAD
NAI
HOH
 2.766
6.444
5.037
 N
N
N
 O2
O7N
O
ALA C:328 C:328 23.0 0.2 H -64.4 -47.6 NA NA NA
ALA D:328 D:328 23.0 0.2 H -67.4 -42.5 NA NA NA
ALA E:328 E:328 22.0 0.191 H -63.6 -46.2 NA NA NA
ALA F:328 F:328 24.0 0.209 H -67.8 -43.0 NA NA NA
ALA G:328 G:328 24.0 0.209 H -62.2 -47.1 NA NA NA
ALA H:328 H:328 24.0 0.209 H -61.2 -46.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ALA A:328 A:328 27.0 0.235 H -62.3 -50.6 14.0 0.122 0.113 B:P09622:0.113
 FAD
HOH
 2.825
5.109
 N
N
 O2
O
ALA B:328 B:328 25.0 0.217 H -63.0 -40.6 12.0 0.104 0.113 A:P09622:0.113
 FAD
HOH
 2.771
6.378
 N
N
 O2
O
ALA C:328 C:328 25.0 0.217 H -59.3 -50.4 NA NA NA
ALA D:328 D:328 23.0 0.2 H -59.1 -55.1 NA NA NA
ALA E:328 E:328 26.0 0.226 H -66.4 -45.1 NA NA NA
ALA F:328 F:328 24.0 0.209 H -64.6 -44.1 NA NA NA
ALA G:328 G:328 25.0 0.217 H -58.1 -50.2 NA NA NA
ALA H:328 H:328 26.0 0.226 H -60.2 -48.2 NA NA NA
ALA I:328 I:328 27.0 0.235 H -63.2 -54.1 NA NA NA
ALA J:328 J:328 24.0 0.209 H -61.0 -57.5 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ALA A:349 A:328 23.0 0.2 H -68.7 -46.6 13.0 0.113 0.087 B:P09622:0.087
 FAD
HOH
 1.943
5.078
 H
HA
 O2
O
ALA B:349 B:328 24.0 0.209 H -68.6 -47.0 15.0 0.13 0.079 A:P09622:0.078
 FAD
HOH
 1.976
4.950
 H
HA
 O2
O
ALA C:349 C:328 25.0 0.217 H -68.0 -46.9 NA NA NA
ALA D:349 D:328 23.0 0.2 H -68.3 -47.1 NA NA NA
ALA E:349 E:328 24.0 0.209 H -68.2 -46.8 NA NA NA
ALA F:349 F:328 22.0 0.191 H -69.8 -47.7 NA NA NA
ALA G:349 G:328 23.0 0.2 H -69.2 -47.0 NA NA NA
ALA H:349 H:328 24.0 0.209 H -69.4 -48.1 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 28.0 0.243 H -63.4 -48.5 14.0 0.122 0.121 B:P09622:0.122
 FAD
HOH
 2.074
4.974
 H
HA
 O2
O
ALA B:350 B:328 23.0 0.2 H -63.3 -50.0 13.0 0.113 0.087 A:P09622:0.087
 FAD
HOH
 2.069
4.812
 H
HA
 O2
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ALA A:350 A:328 24.0 0.209 H -64.4 -53.0 14.0 0.122 0.087 B:P09622:0.087
 FAD
HOH
 2.733
4.950
 N
N
 O2
O
ALA B:350 B:328 22.0 0.191 H -58.2 -50.2 12.0 0.104 0.087 A:P09622:0.087
 FAD
HOH
 2.783
4.874
 N
N
 O2
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ALA A:350 A:328 29.0 0.252 H -70.1 -41.1 13.0 0.113 0.139 B:P09622:0.139
 FAD
HOH
 2.824
3.416
 N
O
 O2
O
ALA B:350 B:328 29.0 0.252 H -63.7 -42.9 13.0 0.113 0.139 A:P09622:0.139
 FAD
HOH
 2.884
5.148
 N
N
 O2
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 29.0 0.252 H -66.7 -44.6 12.0 0.104 0.148 B:P09622:0.148
 FAD
HOH
 2.005
3.077
 H
HB1
 O2
O
ALA B:350 B:328 30.0 0.261 H -67.6 -46.3 13.0 0.113 0.148 A:P09622:0.148
 FAD
HOH
 2.026
4.013
 H
HB1
 O2
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 29.0 0.252 H -62.5 -47.2 14.0 0.122 0.13 B:P09622:0.13
 FAD
HOH
 2.046
3.730
 H
HB1
 O2
O
ALA B:350 B:328 29.0 0.252 H -62.1 -48.6 13.0 0.113 0.139 A:P09622:0.139
 FAD
HOH
 2.070
4.009
 H
HB1
 O2
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 24.0 0.209 H -62.4 -46.0 13.0 0.113 0.096 B:P09622:0.096
 FAD
HOH
 2.060
5.013
 H
HA
 O2
O
ALA B:350 B:328 22.0 0.191 H -63.3 -47.9 13.0 0.113 0.078 A:P09622:0.078
 FAD
HOH
 2.033
4.867
 H
HA
 O2
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ALA A:350 A:328 26.0 0.226 H -66.0 -45.0 15.0 0.13 0.096 B:P09622:0.096
 FAD
HOH
 1.995
5.010
 H
HA
 O2
O
ALA B:350 B:328 26.0 0.226 H -66.4 -44.2 16.0 0.139 0.087 A:P09622:0.087
 FAD
HOH
 1.999
8.472
 H
HB3
 O2
O
ALA C:350 C:328 33.0 0.287 H -66.3 -43.0 NA NA NA
ALA D:350 D:328 30.0 0.261 H -67.8 -44.6 NA NA NA
ALA E:350 E:328 25.0 0.217 H -67.1 -43.8 NA NA NA
ALA F:350 F:328 31.0 0.27 H -66.3 -45.2 NA NA NA
ALA G:350 G:328 26.0 0.226 H -66.8 -44.0 NA NA NA
ALA H:350 H:328 29.0 0.252 H -66.3 -43.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ALA A:363 A:363 26.0 0.226 H -64.5 -51.4