Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107557776 | . | G | A | CCDS5749.1:NM_000108.3:c.1105Gaa>Aaa_NP_000099.2:p.369E>K | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | GLU | A:355 | A:334 | 0.0 | 0.0 | H | -59.1 | -42.3 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.722 5.058 |
OE1 OE1 |
O2P O |
||
| GLU | B:355 | B:334 | 0.0 | 0.0 | H | -59.3 | -50.3 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.758 4.895 |
OE1 OE1 |
O2P O |
|||||||||
| GLU | C:355 | C:334 | 0.0 | 0.0 | H | -57.9 | -44.0 | NA | NA | NA | |||||||||||||
| GLU | D:355 | D:334 | 0.0 | 0.0 | H | -60.2 | -40.9 | NA | NA | NA | |||||||||||||
| 1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | GLU | A:334 | A:334 | 0.0 | 0.0 | H | -59.3 | -32.4 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.707 5.041 |
OE1 OE1 |
O2P O |
||
| GLU | B:334 | B:334 | 0.0 | 0.0 | H | -61.5 | -34.8 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.717 5.549 |
OE1 OE1 |
O2P O |
|||||||||
| GLU | C:334 | C:334 | 0.0 | 0.0 | H | -54.0 | -52.3 | NA | NA | NA | |||||||||||||
| GLU | D:334 | D:334 | 0.0 | 0.0 | H | -47.3 | -50.5 | NA | NA | NA | |||||||||||||
| GLU | E:334 | E:334 | 0.0 | 0.0 | H | -62.6 | -53.7 | NA | NA | NA | |||||||||||||
| GLU | F:334 | F:334 | 1.0 | 0.005 | H | -58.1 | -46.6 | NA | NA | NA | |||||||||||||
| GLU | G:334 | G:334 | 0.0 | 0.0 | H | -65.3 | -45.2 | NA | NA | NA | |||||||||||||
| GLU | H:334 | H:334 | 0.0 | 0.0 | H | -62.1 | -37.1 | NA | NA | NA | |||||||||||||
| GLU | I:334 | I:334 | 0.0 | 0.0 | H | -45.2 | -54.4 | NA | NA | NA | |||||||||||||
| GLU | J:334 | J:334 | 0.0 | 0.0 | H | -85.9 | -49.8 | NA | NA | NA | |||||||||||||
| 6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -61.5 | -42.5 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.909 8.693 3.692 |
OE1 OE2 OE2 |
O1P O4 O |
||
| GLU | B:356 | B:334 | 0.0 | 0.0 | H | -62.9 | -42.1 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.881 8.842 5.069 |
OE1 OE2 OE1 |
O1P O2 O |
|||||||||
| 6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -61.2 | -43.0 | 0.0 | 0.0 | 0.0 |
FAD SO4 1PE HOH |
6.816 8.549 5.802 3.346 |
OE1 OE2 N OE2 |
O1P O4 H161 O |
||
| GLU | B:356 | B:334 | 1.0 | 0.005 | H | -61.0 | -41.9 | 1.0 | 0.005 | 0.0 |
FAD SO4 HOH |
6.860 8.521 4.963 |
OE1 OE2 OE1 |
O2P O2 O |
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| 1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLU | A:334 | A:334 | 0.0 | 0.0 | H | -69.6 | -34.6 | 0.0 | 0.0 | 0.0 |
SO4 FAD HOH |
9.279 6.925 3.613 |
OE2 OE1 OE2 |
O2 O2P O |
||
| GLU | B:334 | B:334 | 0.0 | 0.0 | H | -62.6 | -36.6 | 0.0 | 0.0 | 0.0 |
SO4 FAD HOH |
8.909 6.969 4.636 |
OE2 OE1 OE1 |
O4 O2P O |
|||||||||
| GLU | C:334 | C:334 | 0.0 | 0.0 | H | -59.0 | -39.4 | NA | NA | NA | |||||||||||||
| GLU | D:334 | D:334 | 0.0 | 0.0 | H | -65.7 | -37.2 | NA | NA | NA | |||||||||||||
| GLU | E:334 | E:334 | 0.0 | 0.0 | H | -62.3 | -41.9 | NA | NA | NA | |||||||||||||
| GLU | F:334 | F:334 | 0.0 | 0.0 | H | -63.2 | -37.9 | NA | NA | NA | |||||||||||||
| GLU | G:334 | G:334 | 0.0 | 0.0 | H | -70.8 | -34.8 | NA | NA | NA | |||||||||||||
| GLU | H:334 | H:334 | 0.0 | 0.0 | H | -60.2 | -36.0 | NA | NA | NA | |||||||||||||
| 1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | GLU | A:334 | A:334 | 0.0 | 0.0 | H | -62.5 | -35.6 | 0.0 | 0.0 | 0.0 |
SO4 FAD HOH |
8.824 6.902 3.737 |
OE2 OE1 OE2 |
O2 O2P O |
||
| GLU | B:334 | B:334 | 0.0 | 0.0 | H | -67.1 | -35.8 | 0.0 | 0.0 | 0.0 |
SO4 FAD HOH |
8.888 6.887 4.874 |
OE2 OE1 OE1 |
O4 O2P O |
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| GLU | C:334 | C:334 | 0.0 | 0.0 | H | -62.1 | -39.5 | NA | NA | NA | |||||||||||||
| GLU | D:334 | D:334 | 0.0 | 0.0 | H | -60.6 | -37.5 | NA | NA | NA | |||||||||||||
| GLU | E:334 | E:334 | 0.0 | 0.0 | H | -58.8 | -41.1 | NA | NA | NA | |||||||||||||
| GLU | F:334 | F:334 | 0.0 | 0.0 | H | -61.7 | -39.5 | NA | NA | NA | |||||||||||||
| GLU | G:334 | G:334 | 0.0 | 0.0 | H | -65.7 | -40.1 | NA | NA | NA | |||||||||||||
| GLU | H:334 | H:334 | 0.0 | 0.0 | H | -63.8 | -36.5 | NA | NA | NA | |||||||||||||
| 2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | GLU | A:334 | A:334 | 2.0 | 0.011 | H | -55.3 | -49.0 | 2.0 | 0.011 | 0.0 |
SO4 FAD HOH |
8.544 7.168 5.141 |
OE2 OE1 OE2 |
O2 O2P O |
||
| GLU | B:334 | B:334 | 0.0 | 0.0 | H | -55.9 | -44.9 | 0.0 | 0.0 | 0.0 |
SO4 FAD HOH |
8.312 7.003 7.088 |
OE2 OE1 OE1 |
O4 O2P O |
|||||||||
| GLU | C:334 | C:334 | 0.0 | 0.0 | H | -63.8 | -41.2 | NA | NA | NA | |||||||||||||
| GLU | D:334 | D:334 | 0.0 | 0.0 | H | -64.7 | -39.6 | NA | NA | NA | |||||||||||||
| GLU | E:334 | E:334 | 1.0 | 0.005 | H | -64.6 | -40.0 | NA | NA | NA | |||||||||||||
| GLU | F:334 | F:334 | 0.0 | 0.0 | H | -60.1 | -44.8 | NA | NA | NA | |||||||||||||
| GLU | G:334 | G:334 | 1.0 | 0.005 | H | -71.1 | -41.1 | NA | NA | NA | |||||||||||||
| GLU | H:334 | H:334 | 0.0 | 0.0 | H | -62.0 | -42.1 | NA | NA | NA | |||||||||||||
| GLU | I:334 | I:334 | 0.0 | 0.0 | H | -61.9 | -45.4 | NA | NA | NA | |||||||||||||
| GLU | J:334 | J:334 | 0.0 | 0.0 | H | -62.9 | -37.8 | NA | NA | NA | |||||||||||||
| 5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | GLU | A:355 | A:334 | 0.0 | 0.0 | H | -60.1 | -39.8 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.860 5.127 |
OE1 OE1 |
O2P O |
||
| GLU | B:355 | B:334 | 0.0 | 0.0 | H | -59.8 | -39.1 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.796 5.087 |
OE1 OE1 |
O2P O |
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| GLU | C:355 | C:334 | 0.0 | 0.0 | H | -58.1 | -38.8 | NA | NA | NA | |||||||||||||
| GLU | D:355 | D:334 | 0.0 | 0.0 | H | -58.5 | -38.7 | NA | NA | NA | |||||||||||||
| GLU | E:355 | E:334 | 0.0 | 0.0 | H | -57.9 | -38.0 | NA | NA | NA | |||||||||||||
| GLU | F:355 | F:334 | 0.0 | 0.0 | H | -60.7 | -37.9 | NA | NA | NA | |||||||||||||
| GLU | G:355 | G:334 | 0.0 | 0.0 | H | -61.2 | -39.5 | NA | NA | NA | |||||||||||||
| GLU | H:355 | H:334 | 0.0 | 0.0 | H | -60.8 | -39.1 | NA | NA | NA | |||||||||||||
| 6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -61.3 | -41.5 | 0.0 | 0.0 | 0.0 |
FAD SO4 1PE HOH |
6.783 8.462 5.732 3.954 |
OE1 OE2 N OE2 |
O1P O4 H122 O |
||
| GLU | B:356 | B:334 | 1.0 | 0.005 | H | -61.9 | -40.5 | 1.0 | 0.005 | 0.0 |
FAD SO4 HOH |
6.880 8.578 5.103 |
OE1 OE2 OE1 |
O2P O1 O |
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| 5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -62.3 | -35.3 | 0.0 | 0.0 | 0.0 |
FAD PO4 GOL HOH |
6.911 8.665 6.165 3.401 |
OE1 OE2 N OE2 |
O2P O4 O1 O |
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| GLU | B:356 | B:334 | 0.0 | 0.0 | H | -60.6 | -43.3 | 0.0 | 0.0 | 0.0 |
FAD PO4 HOH |
6.923 8.731 3.396 |
OE1 OE2 OE2 |
O2P O1 O |
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| 6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -61.4 | -40.3 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.869 8.845 3.953 |
OE1 OE2 OE2 |
O2P O4 O |
||
| GLU | B:356 | B:334 | 0.0 | 0.0 | H | -62.6 | -41.3 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.950 9.022 3.930 |
OE1 OE2 OE2 |
O2P O1 O |
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| 6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -62.0 | -40.8 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.895 8.803 3.804 |
OE1 OE2 OE2 |
O2P O4 O |
||
| GLU | B:356 | B:334 | 0.0 | 0.0 | H | -60.9 | -41.2 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.985 8.943 3.402 |
OE1 OE2 OE2 |
O1P O2 O |
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| 6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -64.4 | -39.4 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.921 8.626 3.833 |
OE1 OE2 OE2 |
O2P O4 O |
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| GLU | B:356 | B:334 | 0.0 | 0.0 | H | -64.2 | -39.7 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.917 8.865 4.968 |
OE1 OE2 OE2 |
O1P O2 O |
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| 6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 1.0 | 0.005 | H | -63.2 | -42.2 | 1.0 | 0.005 | 0.0 |
FAD SO4 HOH |
6.912 8.721 3.447 |
OE1 OE2 OE2 |
O2P O4 O |
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| GLU | B:356 | B:334 | 1.0 | 0.005 | H | -64.8 | -41.8 | 1.0 | 0.005 | 0.0 |
FAD SO4 HOH |
7.040 8.932 5.040 |
OE1 OE2 OE1 |
O1P O1 O |
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| 6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:356 | A:334 | 0.0 | 0.0 | H | -61.1 | -39.8 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.686 8.895 3.748 |
OE1 OE2 OE2 |
O1P O4 O |
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| GLU | B:356 | B:334 | 0.0 | 0.0 | H | -61.8 | -37.8 | 0.0 | 0.0 | 0.0 |
FAD SO4 HOH |
6.915 9.236 6.787 |
OE2 OE1 O |
O1P O3 O |
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| GLU | C:356 | C:334 | 0.0 | 0.0 | H | -61.4 | -39.6 | NA | NA | NA | |||||||||||||
| GLU | D:356 | D:334 | 0.0 | 0.0 | H | -60.8 | -35.3 | NA | NA | NA | |||||||||||||
| GLU | E:356 | E:334 | 0.0 | 0.0 | H | -61.1 | -40.1 | NA | NA | NA | |||||||||||||
| GLU | F:356 | F:334 | 0.0 | 0.0 | H | -62.0 | -38.4 | NA | NA | NA | |||||||||||||
| GLU | G:356 | G:334 | 0.0 | 0.0 | H | -61.9 | -38.5 | NA | NA | NA | |||||||||||||
| GLU | H:356 | H:334 | 0.0 | 0.0 | H | -62.0 | -38.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | GLU | A:369 | A:369 | 0.0 | 0.0 | H | -56.4 | -39.1 | |