Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107557790 | . | T | A | CCDS5749.1:NM_000108.3:c.1119tgT>tgA_NP_000099.2:p.373C>* | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | CYS | A:359 | A:338 | 0.0 | 0.0 | H | -60.3 | -52.3 | 0.0 | 0.0 | 0.0 |
HOH |
2.505 |
O |
O |
||
CYS | B:359 | B:338 | 0.0 | 0.0 | H | -67.7 | -55.8 | 0.0 | 0.0 | 0.0 | |||||||||||||
CYS | C:359 | C:338 | 0.0 | 0.0 | H | -57.2 | -50.5 | NA | NA | NA | |||||||||||||
CYS | D:359 | D:338 | 0.0 | 0.0 | H | -56.9 | -48.0 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | CYS | A:338 | A:338 | 0.0 | 0.0 | H | -52.9 | -51.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.852 |
O |
O |
||
CYS | B:338 | B:338 | 0.0 | 0.0 | H | -70.4 | -53.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.047 |
O |
O |
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CYS | C:338 | C:338 | 0.0 | 0.0 | H | -44.4 | -63.3 | NA | NA | NA | |||||||||||||
CYS | D:338 | D:338 | 0.0 | 0.0 | H | -61.7 | -50.6 | NA | NA | NA | |||||||||||||
CYS | E:338 | E:338 | 0.0 | 0.0 | H | -64.1 | -46.3 | NA | NA | NA | |||||||||||||
CYS | F:338 | F:338 | 0.0 | 0.0 | H | -55.9 | -65.8 | NA | NA | NA | |||||||||||||
CYS | G:338 | G:338 | 0.0 | 0.0 | H | -57.2 | -58.8 | NA | NA | NA | |||||||||||||
CYS | H:338 | H:338 | 0.0 | 0.0 | H | -68.6 | -42.9 | NA | NA | NA | |||||||||||||
CYS | I:338 | I:338 | 1.0 | 0.007 | H | -72.8 | -50.0 | NA | NA | NA | |||||||||||||
CYS | J:338 | J:338 | 0.0 | 0.0 | H | -89.2 | -34.0 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -59.3 | -49.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.794 |
O |
O |
||
CYS | B:360 | B:338 | 0.0 | 0.0 | H | -59.5 | -51.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.934 |
O |
O |
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6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -56.4 | -47.7 | 0.0 | 0.0 | 0.0 |
1PE HOH |
6.637 2.749 |
H O |
H162 O |
||
CYS | B:360 | B:338 | 0.0 | 0.0 | H | -58.6 | -47.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.911 |
O |
O |
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1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | CYS | A:338 | A:338 | 0.0 | 0.0 | H | -64.7 | -44.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.800 |
O |
O |
||
CYS | B:338 | B:338 | 0.0 | 0.0 | H | -74.9 | -50.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.792 |
O |
O |
|||||||||
CYS | C:338 | C:338 | 0.0 | 0.0 | H | -77.1 | -44.4 | NA | NA | NA | |||||||||||||
CYS | D:338 | D:338 | 0.0 | 0.0 | H | -60.6 | -49.0 | NA | NA | NA | |||||||||||||
CYS | E:338 | E:338 | 0.0 | 0.0 | H | -77.9 | -38.0 | NA | NA | NA | |||||||||||||
CYS | F:338 | F:338 | 0.0 | 0.0 | H | -58.7 | -52.2 | NA | NA | NA | |||||||||||||
CYS | G:338 | G:338 | 0.0 | 0.0 | H | -64.6 | -48.1 | NA | NA | NA | |||||||||||||
CYS | H:338 | H:338 | 0.0 | 0.0 | H | -64.6 | -44.6 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | CYS | A:338 | A:338 | 0.0 | 0.0 | H | -62.2 | -48.3 | 0.0 | 0.0 | 0.0 |
HOH |
2.772 |
O |
O |
||
CYS | B:338 | B:338 | 0.0 | 0.0 | H | -62.3 | -50.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.634 |
O |
O |
|||||||||
CYS | C:338 | C:338 | 0.0 | 0.0 | H | -67.3 | -45.9 | NA | NA | NA | |||||||||||||
CYS | D:338 | D:338 | 0.0 | 0.0 | H | -62.4 | -47.1 | NA | NA | NA | |||||||||||||
CYS | E:338 | E:338 | 0.0 | 0.0 | H | -65.1 | -50.2 | NA | NA | NA | |||||||||||||
CYS | F:338 | F:338 | 0.0 | 0.0 | H | -60.0 | -49.1 | NA | NA | NA | |||||||||||||
CYS | G:338 | G:338 | 0.0 | 0.0 | H | -64.7 | -45.9 | NA | NA | NA | |||||||||||||
CYS | H:338 | H:338 | 0.0 | 0.0 | H | -63.0 | -52.4 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | CYS | A:338 | A:338 | 1.0 | 0.007 | H | -65.7 | -48.2 | 1.0 | 0.007 | 0.0 |
HOH |
7.722 |
N |
O |
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CYS | B:338 | B:338 | 1.0 | 0.007 | H | -67.9 | -52.3 | 1.0 | 0.007 | 0.0 | |||||||||||||
CYS | C:338 | C:338 | 0.0 | 0.0 | H | -64.6 | -41.8 | NA | NA | NA | |||||||||||||
CYS | D:338 | D:338 | 0.0 | 0.0 | H | -65.1 | -46.9 | NA | NA | NA | |||||||||||||
CYS | E:338 | E:338 | 0.0 | 0.0 | H | -65.0 | -48.6 | NA | NA | NA | |||||||||||||
CYS | F:338 | F:338 | 0.0 | 0.0 | H | -65.3 | -51.5 | NA | NA | NA | |||||||||||||
CYS | G:338 | G:338 | 0.0 | 0.0 | H | -62.0 | -57.0 | NA | NA | NA | |||||||||||||
CYS | H:338 | H:338 | 0.0 | 0.0 | H | -64.0 | -50.3 | NA | NA | NA | |||||||||||||
CYS | I:338 | I:338 | 0.0 | 0.0 | H | -61.2 | -50.4 | NA | NA | NA | |||||||||||||
CYS | J:338 | J:338 | 0.0 | 0.0 | H | -69.0 | -45.3 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | CYS | A:359 | A:338 | 0.0 | 0.0 | H | -62.3 | -48.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.619 |
O |
O |
||
CYS | B:359 | B:338 | 0.0 | 0.0 | H | -60.4 | -48.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.850 |
O |
O |
|||||||||
CYS | C:359 | C:338 | 1.0 | 0.007 | H | -61.7 | -48.4 | NA | NA | NA | |||||||||||||
CYS | D:359 | D:338 | 0.0 | 0.0 | H | -61.5 | -48.7 | NA | NA | NA | |||||||||||||
CYS | E:359 | E:338 | 0.0 | 0.0 | H | -61.5 | -45.6 | NA | NA | NA | |||||||||||||
CYS | F:359 | F:338 | 0.0 | 0.0 | H | -62.6 | -47.8 | NA | NA | NA | |||||||||||||
CYS | G:359 | G:338 | 0.0 | 0.0 | H | -60.3 | -49.6 | NA | NA | NA | |||||||||||||
CYS | H:359 | H:338 | 1.0 | 0.007 | H | -62.0 | -45.2 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -58.2 | -48.6 | 0.0 | 0.0 | 0.0 |
1PE HOH |
6.921 2.709 |
H O |
H222 O |
||
CYS | B:360 | B:338 | 0.0 | 0.0 | H | -60.0 | -51.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.884 |
O |
O |
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5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -59.4 | -45.0 | 0.0 | 0.0 | 0.0 |
GOL HOH |
8.321 2.793 |
N O |
O1 O |
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CYS | B:360 | B:338 | 0.0 | 0.0 | H | -54.7 | -53.0 | 0.0 | 0.0 | 0.0 |
HOH |
2.731 |
O |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -55.3 | -51.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.734 |
O |
O |
||
CYS | B:360 | B:338 | 0.0 | 0.0 | H | -58.6 | -49.5 | 0.0 | 0.0 | 0.0 |
HOH |
2.854 |
O |
O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -60.9 | -48.3 | 0.0 | 0.0 | 0.0 |
HOH |
2.826 |
O |
O |
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CYS | B:360 | B:338 | 0.0 | 0.0 | H | -62.5 | -49.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.880 |
O |
O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -62.2 | -47.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.828 |
O |
O |
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CYS | B:360 | B:338 | 0.0 | 0.0 | H | -60.8 | -48.8 | 0.0 | 0.0 | 0.0 |
HOH |
2.879 |
HA |
O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -59.1 | -50.2 | 0.0 | 0.0 | 0.0 |
HOH |
2.805 |
O |
O |
||
CYS | B:360 | B:338 | 0.0 | 0.0 | H | -60.2 | -51.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.791 |
O |
O |
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6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | CYS | A:360 | A:338 | 0.0 | 0.0 | H | -60.6 | -46.9 | 0.0 | 0.0 | 0.0 |
HOH |
6.801 |
O |
O |
||
CYS | B:360 | B:338 | 0.0 | 0.0 | H | -60.7 | -46.4 | 0.0 | 0.0 | 0.0 |
HOH |
2.426 |
O |
O |
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CYS | C:360 | C:338 | 1.0 | 0.007 | H | -60.8 | -45.9 | NA | NA | NA | |||||||||||||
CYS | D:360 | D:338 | 0.0 | 0.0 | H | -60.6 | -48.1 | NA | NA | NA | |||||||||||||
CYS | E:360 | E:338 | 1.0 | 0.007 | H | -60.5 | -48.0 | NA | NA | NA | |||||||||||||
CYS | F:360 | F:338 | 0.0 | 0.0 | H | -60.0 | -47.7 | NA | NA | NA | |||||||||||||
CYS | G:360 | G:338 | 0.0 | 0.0 | H | -60.9 | -46.6 | NA | NA | NA | |||||||||||||
CYS | H:360 | H:338 | 0.0 | 0.0 | H | -59.6 | -47.6 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | CYS | A:373 | A:373 | 0.0 | 0.0 | H | -61.7 | -48.3 |