Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 107557802 | . | G | A | CCDS5749.1:NM_000108.3:c.1131atG>atA_NP_000099.2:p.377M>I | Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3rnm | 1 | P09622 | 99.37 | 0.0 |
X-RAY |
2011-05-04 | MET | A:363 | A:342 | 25.0 | 0.135 | H | -60.4 | -21.3 | 25.0 | 0.135 | 0.0 |
HOH |
3.429 |
N |
O |
||
MET | B:363 | B:342 | 30.0 | 0.162 | H | -58.2 | -33.2 | 30.0 | 0.162 | 0.0 | |||||||||||||
MET | C:363 | C:342 | 28.0 | 0.151 | H | -64.1 | -27.6 | NA | NA | NA | |||||||||||||
MET | D:363 | D:342 | 31.0 | 0.168 | H | -48.8 | -39.2 | NA | NA | NA | |||||||||||||
1zy8 | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2005-11-15 | MET | A:342 | A:342 | 31.0 | 0.168 | H | -57.3 | -47.1 | 31.0 | 0.168 | 0.0 |
HOH |
3.506 |
N |
O |
||
MET | B:342 | B:342 | 26.0 | 0.141 | H | -58.9 | -30.5 | 26.0 | 0.141 | 0.0 |
HOH |
3.413 |
N |
O |
|||||||||
MET | C:342 | C:342 | 29.0 | 0.157 | H | -51.5 | -29.1 | NA | NA | NA | |||||||||||||
MET | D:342 | D:342 | 23.0 | 0.124 | T | -65.7 | 0.2 | NA | NA | NA | |||||||||||||
MET | E:342 | E:342 | 30.0 | 0.162 | H | -43.2 | -32.3 | NA | NA | NA | |||||||||||||
MET | F:342 | F:342 | 29.0 | 0.157 | H | -62.6 | -16.4 | NA | NA | NA | |||||||||||||
MET | G:342 | G:342 | 26.0 | 0.141 | H | -50.5 | -33.3 | NA | NA | NA | |||||||||||||
MET | H:342 | H:342 | 24.0 | 0.13 | H | -56.0 | -24.7 | NA | NA | NA | |||||||||||||
MET | I:342 | I:342 | 38.0 | 0.205 | T | -87.6 | -0.1 | NA | NA | NA | |||||||||||||
MET | J:342 | J:342 | 25.0 | 0.135 | G | -78.1 | -15.6 | NA | NA | NA | |||||||||||||
6i4q | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 31.0 | 0.168 | H | -58.6 | -35.3 | 31.0 | 0.168 | 0.0 |
SO4 HOH |
9.541 2.951 |
HA O |
O2 O |
||
MET | B:364 | B:342 | 29.0 | 0.157 | H | -59.1 | -37.0 | 29.0 | 0.157 | 0.0 |
HOH |
3.799 |
H |
O |
|||||||||
6i4t | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 29.0 | 0.157 | H | -58.0 | -33.1 | 29.0 | 0.157 | 0.0 |
1PE HOH |
9.070 3.036 |
H HA |
H132 O |
||
MET | B:364 | B:342 | 28.0 | 0.151 | H | -59.3 | -33.4 | 28.0 | 0.151 | 0.0 |
HOH |
3.693 |
H |
O |
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1zmc | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | MET | A:342 | A:342 | 29.0 | 0.157 | H | -59.6 | -30.1 | 29.0 | 0.157 | 0.0 |
HOH |
3.501 |
N |
O |
||
MET | B:342 | B:342 | 28.0 | 0.151 | H | -64.3 | -48.4 | 28.0 | 0.151 | 0.0 |
HOH |
3.412 |
N |
O |
|||||||||
MET | C:342 | C:342 | 28.0 | 0.151 | H | -56.6 | -34.3 | NA | NA | NA | |||||||||||||
MET | D:342 | D:342 | 29.0 | 0.157 | H | -60.2 | -27.1 | NA | NA | NA | |||||||||||||
MET | E:342 | E:342 | 26.0 | 0.141 | H | -70.3 | -31.0 | NA | NA | NA | |||||||||||||
MET | F:342 | F:342 | 30.0 | 0.162 | H | -58.7 | -31.7 | NA | NA | NA | |||||||||||||
MET | G:342 | G:342 | 29.0 | 0.157 | H | -59.0 | -29.9 | NA | NA | NA | |||||||||||||
MET | H:342 | H:342 | 29.0 | 0.157 | H | -67.5 | -40.4 | NA | NA | NA | |||||||||||||
1zmd | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2005-06-28 | MET | A:342 | A:342 | 29.0 | 0.157 | H | -57.8 | -28.2 | 29.0 | 0.157 | 0.0 |
HOH |
3.559 |
N |
O |
||
MET | B:342 | B:342 | 26.0 | 0.141 | H | -62.7 | -33.0 | 26.0 | 0.141 | 0.0 |
HOH |
3.482 |
N |
O |
|||||||||
MET | C:342 | C:342 | 28.0 | 0.151 | H | -59.5 | -24.6 | NA | NA | NA | |||||||||||||
MET | D:342 | D:342 | 29.0 | 0.157 | H | -62.6 | -27.6 | NA | NA | NA | |||||||||||||
MET | E:342 | E:342 | 26.0 | 0.141 | H | -62.8 | -30.9 | NA | NA | NA | |||||||||||||
MET | F:342 | F:342 | 28.0 | 0.151 | H | -64.5 | -31.1 | NA | NA | NA | |||||||||||||
MET | G:342 | G:342 | 29.0 | 0.157 | H | -59.5 | -28.7 | NA | NA | NA | |||||||||||||
MET | H:342 | H:342 | 29.0 | 0.157 | H | -57.0 | -36.6 | NA | NA | NA | |||||||||||||
2f5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2006-01-17 | MET | A:342 | A:342 | 28.0 | 0.151 | H | -61.6 | -22.3 | 28.0 | 0.151 | 0.0 | ||||||
MET | B:342 | B:342 | 28.0 | 0.151 | H | -61.6 | -32.6 | 28.0 | 0.151 | 0.0 | |||||||||||||
MET | C:342 | C:342 | 29.0 | 0.157 | H | -59.8 | -30.3 | NA | NA | NA | |||||||||||||
MET | D:342 | D:342 | 27.0 | 0.146 | H | -59.5 | -30.3 | NA | NA | NA | |||||||||||||
MET | E:342 | E:342 | 30.0 | 0.162 | H | -56.4 | -27.8 | NA | NA | NA | |||||||||||||
MET | F:342 | F:342 | 27.0 | 0.146 | H | -56.4 | -36.7 | NA | NA | NA | |||||||||||||
MET | G:342 | G:342 | 28.0 | 0.151 | H | -54.5 | -35.5 | NA | NA | NA | |||||||||||||
MET | H:342 | H:342 | 26.0 | 0.141 | H | -52.9 | -33.4 | NA | NA | NA | |||||||||||||
MET | I:342 | I:342 | 29.0 | 0.157 | H | -51.0 | -39.5 | NA | NA | NA | |||||||||||||
MET | J:342 | J:342 | 26.0 | 0.141 | H | -52.8 | -41.5 | NA | NA | NA | |||||||||||||
5nhg | 1 | P09622 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | MET | A:363 | A:342 | 28.0 | 0.151 | H | -60.6 | -28.2 | 28.0 | 0.151 | 0.0 |
HOH |
3.101 |
HA |
O |
||
MET | B:363 | B:342 | 26.0 | 0.141 | H | -58.5 | -29.7 | 26.0 | 0.141 | 0.0 |
HOH |
3.586 |
H |
O |
|||||||||
MET | C:363 | C:342 | 28.0 | 0.151 | H | -59.2 | -33.2 | NA | NA | NA | |||||||||||||
MET | D:363 | D:342 | 29.0 | 0.157 | H | -60.5 | -30.5 | NA | NA | NA | |||||||||||||
MET | E:363 | E:342 | 29.0 | 0.157 | H | -59.9 | -32.3 | NA | NA | NA | |||||||||||||
MET | F:363 | F:342 | 26.0 | 0.141 | H | -58.4 | -29.9 | NA | NA | NA | |||||||||||||
MET | G:363 | G:342 | 27.0 | 0.146 | H | -60.4 | -31.5 | NA | NA | NA | |||||||||||||
MET | H:363 | H:342 | 29.0 | 0.157 | H | -57.8 | -30.2 | NA | NA | NA | |||||||||||||
6i4u | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 29.0 | 0.157 | H | -57.0 | -34.4 | 29.0 | 0.157 | 0.0 |
1PE HOH |
9.809 2.963 |
H O |
H141 O |
||
MET | B:364 | B:342 | 29.0 | 0.157 | H | -57.4 | -33.5 | 29.0 | 0.157 | 0.0 |
HOH |
3.685 |
H |
O |
|||||||||
5j5z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2017-11-15 | MET | A:364 | A:342 | 27.0 | 0.146 | H | -58.9 | -27.8 | 27.0 | 0.146 | 0.0 |
HOH |
3.501 |
N |
O |
||
MET | B:364 | B:342 | 29.0 | 0.157 | H | -54.6 | -32.7 | 29.0 | 0.157 | 0.0 |
HOH |
2.935 |
O |
O |
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6hg8 | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-09-04 | MET | A:364 | A:342 | 29.0 | 0.157 | H | -50.7 | -38.8 | 29.0 | 0.157 | 0.0 |
SO4 HOH |
9.648 2.965 |
O O |
O1 O |
||
MET | B:364 | B:342 | 29.0 | 0.157 | H | -62.7 | -35.0 | 29.0 | 0.157 | 0.0 |
HOH |
3.705 |
N |
O |
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6i4r | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 31.0 | 0.168 | H | -56.2 | -33.1 | 31.0 | 0.168 | 0.0 |
HOH |
2.888 |
O |
O |
||
MET | B:364 | B:342 | 29.0 | 0.157 | H | -57.7 | -33.0 | 29.0 | 0.157 | 0.0 |
HOH |
2.850 |
O |
O |
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6i4p | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 30.0 | 0.162 | H | -57.3 | -33.3 | 30.0 | 0.162 | 0.0 |
SO4 HOH |
9.374 2.795 |
HA O |
O2 O |
||
MET | B:364 | B:342 | 30.0 | 0.162 | H | -58.6 | -32.4 | 30.0 | 0.162 | 0.0 |
HOH |
2.888 |
O |
O |
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6i4s | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 27.0 | 0.146 | H | -56.0 | -33.6 | 27.0 | 0.146 | 0.0 |
HOH |
2.825 |
HA |
O |
||
MET | B:364 | B:342 | 28.0 | 0.151 | H | -55.0 | -35.2 | 28.0 | 0.151 | 0.0 |
HOH |
3.267 |
HA |
O |
|||||||||
6i4z | 1 | P09622 | 99.79 | 0.0 |
X-RAY |
2019-11-20 | MET | A:364 | A:342 | 29.0 | 0.157 | H | -60.1 | -32.1 | 29.0 | 0.157 | 0.0 |
HOH |
3.720 |
HG2 |
O |
||
MET | B:364 | B:342 | 27.0 | 0.146 | H | -59.3 | -33.3 | 27.0 | 0.146 | 0.0 |
HOH |
2.957 |
H |
O |
|||||||||
MET | C:364 | C:342 | 29.0 | 0.157 | H | -59.3 | -33.2 | NA | NA | NA | |||||||||||||
MET | D:364 | D:342 | 31.0 | 0.168 | H | -60.0 | -35.1 | NA | NA | NA | |||||||||||||
MET | E:364 | E:342 | 29.0 | 0.157 | H | -61.0 | -32.2 | NA | NA | NA | |||||||||||||
MET | F:364 | F:342 | 29.0 | 0.157 | H | -59.5 | -32.9 | NA | NA | NA | |||||||||||||
MET | G:364 | G:342 | 26.0 | 0.141 | H | -61.1 | -31.8 | NA | NA | NA | |||||||||||||
MET | H:364 | H:342 | 28.0 | 0.151 | H | -59.2 | -32.5 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p09622-f1 | 1 | P09622 | 100.0 | 0.0 | MET | A:377 | A:377 | 29.0 | 0.157 | H | -63.0 | -32.9 |