Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557849 . T A CCDS5749.1:NM_000108.3:c.1178aTt>aAt_NP_000099.2:p.393I>N Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ILE A:379 A:358 0.0 0.0 E -117.1 120.8 0.0 0.0 0.0 FAD
HOH
 6.959
4.570
 CA
CA
 O4
O
ILE B:379 B:358 1.0 0.006 E -112.8 125.4 1.0 0.006 0.0 FAD
HOH
 7.127
4.380
 CA
CA
 O4
O
ILE C:379 C:358 0.0 0.0 E -116.5 124.5 NA NA NA
ILE D:379 D:358 0.0 0.0 E -116.0 123.6 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ILE A:358 A:358 1.0 0.006 E -110.0 123.5 1.0 0.006 0.0 FAD
HOH
 6.348
4.252
 CA
CA
 O4
O
ILE B:358 B:358 0.0 0.0 E -103.8 111.8 0.0 0.0 0.0 FAD
HOH
 6.448
4.191
 CA
CA
 O4
O
ILE C:358 C:358 0.0 0.0 E -105.9 110.4 NA NA NA
ILE D:358 D:358 0.0 0.0 E -111.0 121.1 NA NA NA
ILE E:358 E:358 0.0 0.0 E -92.2 125.4 NA NA NA
ILE F:358 F:358 0.0 0.0 E -116.7 112.4 NA NA NA
ILE G:358 G:358 0.0 0.0 E -115.8 121.1 NA NA NA
ILE H:358 H:358 1.0 0.006 E -111.2 124.2 NA NA NA
ILE I:358 I:358 2.0 0.011 E -128.6 107.6 NA NA NA
ILE J:358 J:358 0.0 0.0 E -109.9 120.8 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -116.9 119.3 0.0 0.0 0.0 FAD
HOH
 6.158
3.607
 HA
HA
 O4
O
ILE B:380 B:358 0.0 0.0 E -117.8 120.1 0.0 0.0 0.0 FAD
HOH
 6.274
3.667
 HA
HA
 O4
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -119.4 119.6 0.0 0.0 0.0 FAD
HOH
 6.245
3.432
 HA
HA
 O4
O
ILE B:380 B:358 0.0 0.0 E -119.9 120.2 0.0 0.0 0.0 FAD
HOH
 6.130
3.662
 HA
HA
 O4
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:358 A:358 0.0 0.0 E -114.0 112.4 0.0 0.0 0.0 FAD
NAD
HOH
 6.785
9.152
5.398
 N
CD1
N
 O4
O2N
O
ILE B:358 B:358 0.0 0.0 E -119.0 115.5 0.0 0.0 0.0 FAD
NAD
HOH
 6.670
8.369
5.501
 N
CD1
O
 O4
O5D
O
ILE C:358 C:358 0.0 0.0 E -117.5 113.6 NA NA NA
ILE D:358 D:358 0.0 0.0 E -117.0 113.1 NA NA NA
ILE E:358 E:358 0.0 0.0 E -113.5 115.0 NA NA NA
ILE F:358 F:358 0.0 0.0 E -119.7 114.0 NA NA NA
ILE G:358 G:358 0.0 0.0 E -117.2 120.1 NA NA NA
ILE H:358 H:358 0.0 0.0 E -114.2 113.9 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:358 A:358 0.0 0.0 E -117.2 120.4 0.0 0.0 0.0 FAD
NAI
HOH
 7.183
4.203
4.837
 CA
CA
CG1
 O4
N7N
O
ILE B:358 B:358 1.0 0.006 E -121.7 120.0 1.0 0.006 0.0 FAD
NAI
HOH
 7.232
4.384
4.966
 CA
CA
CG1
 O4
N7N
O
ILE C:358 C:358 0.0 0.0 E -118.5 120.4 NA NA NA
ILE D:358 D:358 1.0 0.006 E -119.4 116.6 NA NA NA
ILE E:358 E:358 0.0 0.0 E -121.7 119.7 NA NA NA
ILE F:358 F:358 1.0 0.006 E -119.3 118.0 NA NA NA
ILE G:358 G:358 0.0 0.0 E -119.0 121.2 NA NA NA
ILE H:358 H:358 1.0 0.006 E -126.9 118.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ILE A:358 A:358 0.0 0.0 E -117.7 117.3 0.0 0.0 0.0 FAD
HOH
 6.728
4.204
 CA
CA
 O4
O
ILE B:358 B:358 0.0 0.0 E -119.0 112.3 0.0 0.0 0.0 FAD
HOH
 6.659
5.767
 CA
O
 O4
O
ILE C:358 C:358 0.0 0.0 E -121.9 119.0 NA NA NA
ILE D:358 D:358 0.0 0.0 E -127.0 118.9 NA NA NA
ILE E:358 E:358 0.0 0.0 E -118.7 119.8 NA NA NA
ILE F:358 F:358 0.0 0.0 E -120.8 117.8 NA NA NA
ILE G:358 G:358 0.0 0.0 E -123.0 119.1 NA NA NA
ILE H:358 H:358 0.0 0.0 E -121.3 122.4 NA NA NA
ILE I:358 I:358 0.0 0.0 E -127.2 119.2 NA NA NA
ILE J:358 J:358 0.0 0.0 E -121.8 122.4 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ILE A:379 A:358 0.0 0.0 E -120.0 118.8 0.0 0.0 0.0 FAD
HOH
 6.215
3.486
 HA
HA
 O4
O
ILE B:379 B:358 0.0 0.0 E -118.9 118.3 0.0 0.0 0.0 FAD
HOH
 6.140
3.621
 HA
HA
 O4
O
ILE C:379 C:358 0.0 0.0 E -117.5 117.8 NA NA NA
ILE D:379 D:358 0.0 0.0 E -120.9 118.1 NA NA NA
ILE E:379 E:358 0.0 0.0 E -119.6 118.8 NA NA NA
ILE F:379 F:358 0.0 0.0 E -119.3 118.4 NA NA NA
ILE G:379 G:358 0.0 0.0 E -119.3 118.2 NA NA NA
ILE H:379 H:358 0.0 0.0 E -120.4 118.2 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -116.8 120.3 0.0 0.0 0.0 FAD
HOH
 6.141
3.527
 HA
HA
 O4
O
ILE B:380 B:358 0.0 0.0 E -115.7 118.1 0.0 0.0 0.0 FAD
HOH
 6.180
3.741
 HA
HA
 O4
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ILE A:380 A:358 0.0 0.0 E -116.8 120.6 0.0 0.0 0.0 FAD
HOH
 6.835
4.373
 CA
CA
 O4
O
ILE B:380 B:358 0.0 0.0 E -116.1 120.5 0.0 0.0 0.0 FAD
HOH
 6.881
4.450
 CA
CA
 O4
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ILE A:380 A:358 0.0 0.0 E -119.0 122.8 0.0 0.0 0.0 FAD
HOH
 6.916
4.419
 CA
CA
 O4
O
ILE B:380 B:358 0.0 0.0 E -119.9 125.7 0.0 0.0 0.0 FAD
SO4
HOH
 6.798
9.330
4.489
 CA
CD1
CA
 O4
O3
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -116.6 122.1 0.0 0.0 0.0 FAD
HOH
 6.245
3.564
 HA
HA
 O4
O
ILE B:380 B:358 0.0 0.0 E -117.8 122.2 0.0 0.0 0.0 FAD
HOH
 6.207
3.542
 HA
HA
 O4
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -116.2 122.3 0.0 0.0 0.0 FAD
HOH
 6.224
3.504
 HA
HA
 O4
O
ILE B:380 B:358 0.0 0.0 E -120.3 121.6 0.0 0.0 0.0 FAD
HOH
 6.271
3.530
 HA
HA
 O4
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -113.5 120.4 0.0 0.0 0.0 FAD
HOH
 6.233
3.501
 HA
HA
 O4
O
ILE B:380 B:358 0.0 0.0 E -113.7 120.8 0.0 0.0 0.0 FAD
HOH
 6.136
3.689
 HA
HA
 O4
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:380 A:358 0.0 0.0 E -115.9 121.2 0.0 0.0 0.0 FAD
HOH
 6.165
4.142
 HA
HG12
 O4
O
ILE B:380 B:358 0.0 0.0 E -113.9 120.3 0.0 0.0 0.0 FAD
HOH
 6.251
6.711
 HA
HG22
 O4
O
ILE C:380 C:358 0.0 0.0 E -114.6 121.7 NA NA NA
ILE D:380 D:358 0.0 0.0 E -113.1 121.6 NA NA NA
ILE E:380 E:358 0.0 0.0 E -113.0 121.0 NA NA NA
ILE F:380 F:358 1.0 0.006 E -114.1 122.1 NA NA NA
ILE G:380 G:358 0.0 0.0 E -114.6 120.4 NA NA NA
ILE H:380 H:358 0.0 0.0 E -113.8 121.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ILE A:393 A:393 0.0 0.0 E -111.5 116.8