Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557890 . G A CCDS5749.1:NM_000108.3:c.1219Gag>Aag_NP_000099.2:p.407E>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 GLU A:393 A:372 66.0 0.347 H -62.1 -41.3 66.0 0.347 0.0 HOH
 2.859
 OE1
 O
GLU B:393 B:372 69.0 0.363 H -47.3 -47.5 69.0 0.363 0.0 HOH
 2.940
 OE2
 O
GLU C:393 C:372 46.0 0.242 H -64.3 -41.8 NA NA NA
GLU D:393 D:372 61.0 0.321 H -57.0 -46.7 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 GLU A:372 A:372 45.0 0.237 H -74.6 -40.7 45.0 0.237 0.0 HOH
 8.135
 OE1
 O
GLU B:372 B:372 59.0 0.311 H -81.5 -22.8 59.0 0.311 0.0 HOH
 6.653
 OE2
 O
GLU C:372 C:372 64.0 0.337 H -57.7 -46.9 NA NA NA
GLU D:372 D:372 57.0 0.3 H -63.6 -43.4 NA NA NA
GLU E:372 E:372 55.0 0.289 H -70.1 -34.9 NA NA NA
GLU F:372 F:372 55.0 0.289 H -70.1 -30.6 NA NA NA
GLU G:372 G:372 47.0 0.247 H -59.4 -43.8 NA NA NA
GLU H:372 H:372 50.0 0.263 H -56.7 -36.3 NA NA NA
GLU I:372 I:372 57.0 0.3 H -49.5 -75.0 NA NA NA
GLU J:372 J:372 58.0 0.305 H -61.3 -68.6 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 57.0 0.3 H -63.2 -40.4 57.0 0.3 0.0 SO4
HOH
 7.104
2.674
 HG2
OE2
 O1
O
GLU B:394 B:372 58.0 0.305 H -62.1 -42.4 58.0 0.305 0.0 SO4
HOH
 7.343
2.690
 HG2
OE1
 O4
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 64.0 0.337 H -63.7 -41.3 64.0 0.337 0.0 SO4
HOH
 6.947
2.553
 HG2
OE2
 O1
O
GLU B:394 B:372 64.0 0.337 H -60.6 -40.5 64.0 0.337 0.0 SO4
HOH
 7.320
2.718
 HG2
OE2
 O3
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:372 A:372 70.0 0.368 H -57.0 -41.0 70.0 0.368 0.0 SO4
HOH
 7.731
3.002
 CG
OE1
 O3
O
GLU B:372 B:372 72.0 0.379 H -60.2 -39.7 72.0 0.379 0.0 SO4
HOH
 7.899
2.504
 CG
OE2
 O3
O
GLU C:372 C:372 75.0 0.395 H -60.0 -37.4 NA NA NA
GLU D:372 D:372 66.0 0.347 H -57.9 -38.8 NA NA NA
GLU E:372 E:372 72.0 0.379 H -62.9 -35.9 NA NA NA
GLU F:372 F:372 72.0 0.379 H -56.8 -47.3 NA NA NA
GLU G:372 G:372 70.0 0.368 H -54.6 -40.6 NA NA NA
GLU H:372 H:372 69.0 0.363 H -64.5 -40.3 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:372 A:372 70.0 0.368 H -64.4 -35.0 70.0 0.368 0.0 HOH
 2.624
 OE1
 O
GLU B:372 B:372 76.0 0.4 H -62.1 -42.1 76.0 0.4 0.0 HOH
 2.699
 OE2
 O
GLU C:372 C:372 73.0 0.384 H -62.2 -41.7 NA NA NA
GLU D:372 D:372 69.0 0.363 H -62.1 -36.5 NA NA NA
GLU E:372 E:372 73.0 0.384 H -62.9 -41.3 NA NA NA
GLU F:372 F:372 71.0 0.374 H -60.0 -41.9 NA NA NA
GLU G:372 G:372 66.0 0.347 H -63.4 -37.7 NA NA NA
GLU H:372 H:372 72.0 0.379 H -62.7 -39.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 GLU A:372 A:372 76.0 0.4 H -55.7 -42.9 76.0 0.4 0.0 SO4
HOH
 7.318
2.881
 CG
OE2
 O1
O
GLU B:372 B:372 71.0 0.374 H -66.9 -43.6 71.0 0.374 0.0 SO4
 7.603
 CG
 O1
GLU C:372 C:372 59.0 0.311 H -56.8 -46.0 NA NA NA
GLU D:372 D:372 63.0 0.332 H -60.6 -39.4 NA NA NA
GLU E:372 E:372 63.0 0.332 H -58.3 -48.3 NA NA NA
GLU F:372 F:372 69.0 0.363 H -61.7 -36.9 NA NA NA
GLU G:372 G:372 74.0 0.389 H -66.0 -34.4 NA NA NA
GLU H:372 H:372 65.0 0.342 H -63.2 -39.0 NA NA NA
GLU I:372 I:372 61.0 0.321 H -60.2 -41.3 NA NA NA
GLU J:372 J:372 73.0 0.384 H -63.4 -37.7 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 GLU A:393 A:372 69.0 0.363 H -62.9 -41.5 69.0 0.363 0.0 HOH
 2.514
 OE2
 O
GLU B:393 B:372 64.0 0.337 H -63.8 -41.2 64.0 0.337 0.0 HOH
 2.754
 OE2
 O
GLU C:393 C:372 77.0 0.405 H -62.3 -41.0 NA NA NA
GLU D:393 D:372 74.0 0.389 H -65.4 -42.8 NA NA NA
GLU E:393 E:372 76.0 0.4 H -64.3 -43.2 NA NA NA
GLU F:393 F:372 73.0 0.384 H -63.4 -41.9 NA NA NA
GLU G:393 G:372 71.0 0.374 H -65.9 -42.4 NA NA NA
GLU H:393 H:372 69.0 0.363 H -64.2 -42.3 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 55.0 0.289 H -64.7 -38.5 55.0 0.289 0.0 SO4
HOH
 6.704
2.710
 HG2
OE1
 O1
O
GLU B:394 B:372 55.0 0.289 H -64.1 -39.7 55.0 0.289 0.0 SO4
HOH
 7.194
2.670
 HG2
OE1
 O4
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 GLU A:394 A:372 62.0 0.326 H -52.7 -48.1 62.0 0.326 0.0 HOH
 2.493
 OE1
 O
GLU B:394 B:372 61.0 0.321 H -64.3 -43.0 61.0 0.321 0.0 HOH
 2.583
 OE1
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 GLU A:394 A:372 61.0 0.321 H -59.6 -44.8 61.0 0.321 0.0 SO4
HOH
 7.867
2.556
 CG
OE1
 O2
O
GLU B:394 B:372 74.0 0.389 H -61.8 -39.2 74.0 0.389 0.0 SO4
HOH
 7.858
2.664
 CG
OE2
 O3
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 60.0 0.316 H -64.6 -38.6 60.0 0.316 0.0 SO4
HOH
 7.031
2.720
 HG2
OE1
 O2
O
GLU B:394 B:372 73.0 0.384 H -64.8 -38.7 73.0 0.384 0.0 SO4
HOH
 7.222
2.628
 HG2
HB2
 O3
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 69.0 0.363 H -65.3 -39.1 69.0 0.363 0.0 SO4
HOH
 7.230
2.719
 HG2
OE2
 O4
O
GLU B:394 B:372 74.0 0.389 H -64.9 -40.0 74.0 0.389 0.0 SO4
HOH
 7.256
2.701
 HG2
HB2
 O3
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 63.0 0.332 H -65.4 -38.8 63.0 0.332 0.0 SO4
HOH
 6.154
2.482
 HG2
OE1
 O3
O
GLU B:394 B:372 69.0 0.363 H -64.6 -37.2 69.0 0.363 0.0 SO4
HOH
 6.864
2.698
 HG2
OE1
 O4
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:394 A:372 72.0 0.379 H -59.8 -44.2 72.0 0.379 0.0 SO4
HOH
 7.343
2.670
 HG2
OE2
 O1
O
GLU B:394 B:372 56.0 0.295 H -62.2 -44.0 56.0 0.295 0.0 HOH
 2.087
 HA
 O
GLU C:394 C:372 69.0 0.363 H -60.6 -42.6 NA NA NA
GLU D:394 D:372 74.0 0.389 H -61.7 -43.4 NA NA NA
GLU E:394 E:372 72.0 0.379 H -62.1 -44.4 NA NA NA
GLU F:394 F:372 58.0 0.305 H -62.0 -43.2 NA NA NA
GLU G:394 G:372 51.0 0.268 H -62.7 -42.3 NA NA NA
GLU H:394 H:372 62.0 0.326 H -61.7 -43.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 GLU A:407 A:407 50.0 0.263 H -63.1 -45.7