Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107558450 . A C CCDS5749.1:NM_000108.3:c.1318Aag>Cag_NP_000099.2:p.440K>Q Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 LYS A:426 A:405 0.0 0.0 E -127.0 123.5 0.0 0.0 0.0 NHE
HOH
 7.461
3.347
 N
NZ
 C3'
O
LYS B:426 B:405 0.0 0.0 E -116.1 123.6 0.0 0.0 0.0 NHE
HOH
 7.670
3.491
 CB
NZ
 C6'
O
LYS C:426 C:405 0.0 0.0 E -134.2 123.5 NA NA NA
LYS D:426 D:405 0.0 0.0 E -127.2 124.2 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 LYS A:405 A:405 0.0 0.0 E -104.9 123.5 0.0 0.0 0.0
LYS B:405 B:405 1.0 0.005 E -130.0 113.1 1.0 0.005 0.0 HOH
 7.132
 CD
 O
LYS C:405 C:405 0.0 0.0 E -127.1 118.5 NA NA NA
LYS D:405 D:405 0.0 0.0 E -134.4 118.9 NA NA NA
LYS E:405 E:405 0.0 0.0 E -140.3 131.7 NA NA NA
LYS F:405 F:405 0.0 0.0 E -121.1 122.2 NA NA NA
LYS G:405 G:405 0.0 0.0 E -132.9 116.2 NA NA NA
LYS H:405 H:405 1.0 0.005 E -124.0 112.0 NA NA NA
LYS I:405 I:405 0.0 0.0 E -138.1 117.4 NA NA NA
LYS J:405 J:405 0.0 0.0 E -128.0 123.1 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 1.0 0.005 E -119.8 127.1 1.0 0.005 0.0 HOH
 2.884
 HZ2
 O
LYS B:427 B:405 0.0 0.0 E -120.2 126.6 0.0 0.0 0.0 HOH
 3.082
 HZ3
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 0.0 0.0 E -120.1 126.6 0.0 0.0 0.0 HOH
 3.090
 HZ1
 O
LYS B:427 B:405 0.0 0.0 E -121.3 126.0 0.0 0.0 0.0 HOH
 2.978
 HZ3
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:405 A:405 0.0 0.0 E -127.8 115.7 0.0 0.0 0.0 HOH
 3.841
 NZ
 O
LYS B:405 B:405 0.0 0.0 E -127.1 121.5 0.0 0.0 0.0 HOH
 3.623
 NZ
 O
LYS C:405 C:405 0.0 0.0 E -126.7 119.4 NA NA NA
LYS D:405 D:405 0.0 0.0 E -117.1 123.9 NA NA NA
LYS E:405 E:405 0.0 0.0 E -121.3 123.1 NA NA NA
LYS F:405 F:405 0.0 0.0 E -114.6 130.4 NA NA NA
LYS G:405 G:405 0.0 0.0 E -129.1 126.0 NA NA NA
LYS H:405 H:405 0.0 0.0 E -126.3 122.4 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:405 A:405 0.0 0.0 E -127.4 124.1 0.0 0.0 0.0 HOH
 3.536
 NZ
 O
LYS B:405 B:405 0.0 0.0 E -122.6 123.9 0.0 0.0 0.0 HOH
 3.461
 NZ
 O
LYS C:405 C:405 1.0 0.005 E -120.0 121.6 NA NA NA
LYS D:405 D:405 0.0 0.0 E -115.9 124.7 NA NA NA
LYS E:405 E:405 0.0 0.0 E -125.8 121.7 NA NA NA
LYS F:405 F:405 0.0 0.0 E -118.7 124.8 NA NA NA
LYS G:405 G:405 0.0 0.0 E -131.5 126.4 NA NA NA
LYS H:405 H:405 0.0 0.0 E -125.7 125.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 LYS A:405 A:405 0.0 0.0 E -119.6 124.2 0.0 0.0 0.0 HOH
 3.626
 NZ
 O
LYS B:405 B:405 0.0 0.0 E -124.7 126.7 0.0 0.0 0.0 HOH
 7.578
 CG
 O
LYS C:405 C:405 0.0 0.0 E -125.1 121.7 NA NA NA
LYS D:405 D:405 0.0 0.0 E -123.0 122.2 NA NA NA
LYS E:405 E:405 0.0 0.0 E -122.1 124.8 NA NA NA
LYS F:405 F:405 0.0 0.0 E -123.7 126.8 NA NA NA
LYS G:405 G:405 0.0 0.0 E -124.1 122.2 NA NA NA
LYS H:405 H:405 1.0 0.005 E -123.4 124.1 NA NA NA
LYS I:405 I:405 1.0 0.005 E -127.0 119.2 NA NA NA
LYS J:405 J:405 0.0 0.0 E -126.7 123.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 LYS A:426 A:405 2.0 0.01 E -119.6 125.9 2.0 0.01 0.0 HOH
 3.124
 HZ1
 O
LYS B:426 B:405 1.0 0.005 E -118.7 127.8 1.0 0.005 0.0 HOH
 2.947
 HZ1
 O
LYS C:426 C:405 0.0 0.0 E -119.0 126.6 NA NA NA
LYS D:426 D:405 0.0 0.0 E -121.0 126.9 NA NA NA
LYS E:426 E:405 1.0 0.005 E -119.4 125.7 NA NA NA
LYS F:426 F:405 1.0 0.005 E -120.1 125.6 NA NA NA
LYS G:426 G:405 1.0 0.005 E -119.1 126.8 NA NA NA
LYS H:426 H:405 1.0 0.005 E -121.0 125.6 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 0.0 0.0 E -122.9 127.0 0.0 0.0 0.0 HOH
 2.742
 HZ3
 O
LYS B:427 B:405 0.0 0.0 E -121.8 127.2 0.0 0.0 0.0 HOH
 2.809
 HZ1
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 LYS A:427 A:405 0.0 0.0 E -122.2 128.4 0.0 0.0 0.0 HOH
 3.603
 NZ
 O
LYS B:427 B:405 0.0 0.0 E -123.0 127.7 0.0 0.0 0.0 HOH
 3.724
 NZ
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 LYS A:427 A:405 0.0 0.0 E -122.8 125.4 0.0 0.0 0.0 HOH
 3.348
 NZ
 O
LYS B:427 B:405 0.0 0.0 E -120.7 124.3 0.0 0.0 0.0 HOH
 3.760
 NZ
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 1.0 0.005 E -122.4 125.1 1.0 0.005 0.0 HOH
 2.908
 HZ1
 O
LYS B:427 B:405 1.0 0.005 E -122.3 125.5 1.0 0.005 0.0 HOH
 2.995
 HZ1
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 0.0 0.0 E -119.0 128.4 0.0 0.0 0.0 HOH
 3.155
 HZ2
 O
LYS B:427 B:405 0.0 0.0 E -118.7 128.6 0.0 0.0 0.0 HOH
 3.139
 HZ2
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 0.0 0.0 E -121.2 126.0 0.0 0.0 0.0 HOH
 2.825
 HZ1
 O
LYS B:427 B:405 0.0 0.0 E -122.3 123.6 0.0 0.0 0.0 HOH
 2.944
 HZ3
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:427 A:405 3.0 0.015 E -120.1 124.9 3.0 0.015 0.0 HOH
 3.295
 HZ2
 O
LYS B:427 B:405 0.0 0.0 E -120.3 125.2 0.0 0.0 0.0 HOH
 3.033
 HZ1
 O
LYS C:427 C:405 0.0 0.0 E -121.1 124.1 NA NA NA
LYS D:427 D:405 0.0 0.0 E -120.7 124.3 NA NA NA
LYS E:427 E:405 0.0 0.0 E -122.3 124.4 NA NA NA
LYS F:427 F:405 0.0 0.0 E -120.4 124.3 NA NA NA
LYS G:427 G:405 1.0 0.005 E -120.2 124.2 NA NA NA
LYS H:427 H:405 0.0 0.0 E -121.2 124.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:440 A:440 1.0 0.005 E -130.2 126.9