Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107559473 . A C CCDS5749.1:NM_000108.3:c.1393Aat>Cat_NP_000099.2:p.465N>H Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ASN A:451 A:430 81.0 0.506 H -74.7 -31.9 0.0 0.0 0.506 B:P09622:0.506
 HOH
 4.099
 CB
 O
ASN B:451 B:430 83.0 0.519 H -70.9 -30.2 0.0 0.0 0.519 A:P09622:0.519
 HOH
 4.137
 CB
 O
ASN C:451 C:430 83.0 0.519 H -72.5 -31.6 NA NA NA
ASN D:451 D:430 82.0 0.512 H -77.2 -30.9 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ASN A:430 A:430 80.0 0.5 H -80.4 -48.1 0.0 0.0 0.5 B:P09622:0.5
 HOH
 4.115
 CB
 O
ASN B:430 B:430 84.0 0.525 H -68.7 -43.3 0.0 0.0 0.525 A:P09622:0.525
 HOH
 5.851
 C
 O
ASN C:430 C:430 86.0 0.537 H -58.8 -38.3 NA NA NA
ASN D:430 D:430 84.0 0.525 H -77.1 -21.5 NA NA NA
ASN E:430 E:430 84.0 0.525 H -68.5 -28.8 NA NA NA
ASN F:430 F:430 84.0 0.525 H -84.3 -18.4 NA NA NA
ASN G:430 G:430 86.0 0.537 H -62.9 -41.2 NA NA NA
ASN H:430 H:430 82.0 0.512 H -70.3 -26.1 NA NA NA
ASN I:430 I:430 90.0 0.562 H -79.3 -25.2 NA NA NA
ASN J:430 J:430 88.0 0.55 H -60.6 -36.8 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 84.0 0.525 H -73.6 -34.0 0.0 0.0 0.525 B:P09622:0.525
 FAD
HOH
 9.399
3.239
 HD21
HB2
 HN3
O
ASN B:452 B:430 82.0 0.512 H -72.5 -30.8 0.0 0.0 0.512 A:P09622:0.512
 FAD
HOH
 9.317
3.308
 HD21
HB2
 HN3
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 84.0 0.525 H -71.1 -34.3 0.0 0.0 0.525 B:P09622:0.525
 FAD
HOH
 9.491
3.147
 HD21
HB2
 HN3
O
ASN B:452 B:430 81.0 0.506 H -70.9 -29.8 0.0 0.0 0.506 A:P09622:0.506
 FAD
HOH
 9.523
3.319
 HD21
HB2
 HN3
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ASN A:430 A:430 84.0 0.525 H -71.0 -30.1 0.0 0.0 0.525 B:P09622:0.525
 HOH
 5.092
 ND2
 O
ASN B:430 B:430 79.0 0.494 H -78.4 -19.5 0.0 0.0 0.494 A:P09622:0.494
 HOH
 4.198
 CB
 O
ASN C:430 C:430 82.0 0.512 H -80.6 -21.7 NA NA NA
ASN D:430 D:430 82.0 0.512 H -69.3 -31.7 NA NA NA
ASN E:430 E:430 83.0 0.519 H -72.7 -26.5 NA NA NA
ASN F:430 F:430 83.0 0.519 H -71.7 -29.6 NA NA NA
ASN G:430 G:430 79.0 0.494 H -78.8 -30.8 NA NA NA
ASN H:430 H:430 83.0 0.519 H -69.0 -26.1 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ASN A:430 A:430 81.0 0.506 H -74.1 -33.9 0.0 0.0 0.506 B:P09622:0.506
 HOH
 4.246
 CB
 O
ASN B:430 B:430 81.0 0.506 H -76.5 -28.5 0.0 0.0 0.506 A:P09622:0.506
 HOH
 4.369
 CB
 O
ASN C:430 C:430 83.0 0.519 H -77.7 -27.1 NA NA NA
ASN D:430 D:430 84.0 0.525 H -75.3 -30.6 NA NA NA
ASN E:430 E:430 82.0 0.512 H -75.1 -28.7 NA NA NA
ASN F:430 F:430 82.0 0.512 H -72.4 -28.4 NA NA NA
ASN G:430 G:430 79.0 0.494 H -72.2 -32.9 NA NA NA
ASN H:430 H:430 82.0 0.512 H -73.2 -29.9 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ASN A:430 A:430 81.0 0.506 H -77.7 -26.6 0.0 0.0 0.506 B:P09622:0.506
 HOH
 5.134
 ND2
 O
ASN B:430 B:430 84.0 0.525 H -71.4 -22.8 0.0 0.0 0.525 A:P09622:0.525
 HOH
 5.572
 ND2
 O
ASN C:430 C:430 80.0 0.5 H -72.5 -29.8 NA NA NA
ASN D:430 D:430 78.0 0.487 H -73.0 -33.0 NA NA NA
ASN E:430 E:430 80.0 0.5 H -75.0 -29.8 NA NA NA
ASN F:430 F:430 82.0 0.512 H -73.8 -31.8 NA NA NA
ASN G:430 G:430 81.0 0.506 H -73.1 -29.0 NA NA NA
ASN H:430 H:430 82.0 0.512 H -77.2 -27.5 NA NA NA
ASN I:430 I:430 82.0 0.512 H -78.3 -29.6 NA NA NA
ASN J:430 J:430 83.0 0.519 H -73.1 -32.7 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ASN A:451 A:430 86.0 0.537 H -74.0 -31.7 0.0 0.0 0.537 B:P09622:0.537
 FAD
HOH
 9.553
3.245
 HD21
HB2
 HN3
O
ASN B:451 B:430 84.0 0.525 H -72.6 -32.2 0.0 0.0 0.525 A:P09622:0.525
 FAD
HOH
 9.503
4.474
 HD21
HD22
 HN3
O
ASN C:451 C:430 84.0 0.525 H -72.7 -33.4 NA NA NA
ASN D:451 D:430 84.0 0.525 H -72.5 -34.0 NA NA NA
ASN E:451 E:430 84.0 0.525 H -72.7 -32.3 NA NA NA
ASN F:451 F:430 82.0 0.512 H -73.3 -33.3 NA NA NA
ASN G:451 G:430 86.0 0.537 H -72.6 -30.8 NA NA NA
ASN H:451 H:430 82.0 0.512 H -72.4 -34.5 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 82.0 0.512 H -74.0 -35.9 0.0 0.0 0.512 B:P09622:0.512
 FAD
HOH
 9.578
3.108
 HD21
HB2
 HN3
O
ASN B:452 B:430 82.0 0.512 H -73.6 -35.0 0.0 0.0 0.512 A:P09622:0.512
 FAD
HOH
 9.180
3.125
 HD21
HB2
 HN3
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ASN A:452 A:430 80.0 0.5 H -70.3 -35.3 0.0 0.0 0.5 B:P09622:0.5
 HOH
 4.022
 CB
 O
ASN B:452 B:430 84.0 0.525 H -70.1 -29.0 0.0 0.0 0.525 A:P09622:0.525
 HOH
 4.052
 CB
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ASN A:452 A:430 82.0 0.512 H -68.1 -37.7 0.0 0.0 0.512 B:P09622:0.512
 SO4
HOH
 8.969
3.940
 ND2
C
 O2
O
ASN B:452 B:430 83.0 0.519 H -71.0 -31.7 0.0 0.0 0.519 A:P09622:0.519
 HOH
 4.009
 CB
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 81.0 0.506 H -75.7 -33.2 0.0 0.0 0.506 B:P09622:0.506
 FAD
HOH
 9.505
3.263
 HD21
HB2
 HN3
O
ASN B:452 B:430 81.0 0.506 H -74.0 -30.3 0.0 0.0 0.506 A:P09622:0.506
 FAD
HOH
 9.558
3.136
 HD21
HB2
 HN3
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 84.0 0.525 H -75.7 -34.5 0.0 0.0 0.525 B:P09622:0.525
 FAD
HOH
 9.562
3.307
 HD21
HB2
 HN3
O
ASN B:452 B:430 80.0 0.5 H -73.6 -30.4 0.0 0.0 0.5 A:P09622:0.5
 FAD
HOH
 9.569
3.163
 HD21
HB2
 HN3
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 79.0 0.494 H -74.9 -33.1 0.0 0.0 0.494 B:P09622:0.494
 FAD
HOH
 9.403
3.279
 HD21
HB2
 HN3
O
ASN B:452 B:430 81.0 0.506 H -73.3 -28.6 0.0 0.0 0.506 A:P09622:0.506
 FAD
HOH
 9.439
3.161
 HD21
HB2
 HN3
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASN A:452 A:430 84.0 0.525 H -69.3 -35.1 0.0 0.0 0.525 B:P09622:0.525
 FAD
HOH
 9.941
7.838
 HD21
HD21
 HN3
O
ASN B:452 B:430 87.0 0.544 H -67.6 -38.2 1.0 0.006 0.538 A:P09622:0.537
 FAD
HOH
 9.537
8.362
 HD21
HD21
 HN3
O
ASN C:452 C:430 87.0 0.544 H -71.3 -35.5 NA NA NA
ASN D:452 D:430 86.0 0.537 H -68.6 -36.5 NA NA NA
ASN E:452 E:430 86.0 0.537 H -70.0 -34.9 NA NA NA
ASN F:452 F:430 81.0 0.506 H -72.2 -35.3 NA NA NA
ASN G:452 G:430 85.0 0.531 H -70.9 -35.9 NA NA NA
ASN H:452 H:430 85.0 0.531 H -72.8 -33.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ASN A:465 A:465 82.0 0.512 H -70.7 -31.7