Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107559476 . G A CCDS5749.1:NM_000108.3:c.1396Gaa>Aaa_NP_000099.2:p.466E>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 GLU A:452 A:431 66.0 0.347 H -62.7 -39.1 5.0 0.026 0.321 B:P09622:0.321
 HOH
 2.991
 OE1
 O
GLU B:452 B:431 65.0 0.342 H -68.1 -40.3 5.0 0.026 0.316 A:P09622:0.316
 HOH
 2.640
 OE1
 O
GLU C:452 C:431 66.0 0.347 H -63.9 -40.9 NA NA NA
GLU D:452 D:431 66.0 0.347 H -63.6 -44.2 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 GLU A:431 A:431 51.0 0.268 H -38.3 -54.0 3.0 0.016 0.252 B:P09622:0.253
 HOH
 3.697
 N
 O
GLU B:431 B:431 56.0 0.295 H -51.2 -41.8 4.0 0.021 0.274 A:P09622:0.274
 HOH
 3.011
 OE1
 O
GLU C:431 C:431 55.0 0.289 H -66.2 -46.1 NA NA NA
GLU D:431 D:431 64.0 0.337 H -81.2 -48.6 NA NA NA
GLU E:431 E:431 56.0 0.295 H -79.6 -34.3 NA NA NA
GLU F:431 F:431 50.0 0.263 H -74.7 -31.2 NA NA NA
GLU G:431 G:431 59.0 0.311 H -55.8 -52.3 NA NA NA
GLU H:431 H:431 57.0 0.3 H -63.6 -46.8 NA NA NA
GLU I:431 I:431 56.0 0.295 H -59.2 -60.7 NA NA NA
GLU J:431 J:431 58.0 0.305 H -69.0 -44.8 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 64.0 0.337 H -59.4 -41.3 6.0 0.032 0.305 B:P09622:0.305
 HOH
 2.509
 H
 O
GLU B:453 B:431 63.0 0.332 H -59.4 -43.0 6.0 0.032 0.3 A:P09622:0.3
 HOH
 2.759
 OE1
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 59.0 0.311 H -59.8 -39.3 6.0 0.032 0.279 B:P09622:0.279
 HOH
 2.331
 H
 O
GLU B:453 B:431 53.0 0.279 H -59.9 -41.0 5.0 0.026 0.253 A:P09622:0.253
 HOH
 2.771
 OE2
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:431 A:431 63.0 0.332 H -71.1 -42.4 6.0 0.032 0.3 B:P09622:0.3
 HOH
 2.961
 OE1
 O
GLU B:431 B:431 62.0 0.326 H -75.7 -33.8 5.0 0.026 0.3 A:P09622:0.3
 HOH
 4.611
 N
 O
GLU C:431 C:431 63.0 0.332 H -77.2 -36.3 NA NA NA
GLU D:431 D:431 63.0 0.332 H -67.7 -45.0 NA NA NA
GLU E:431 E:431 65.0 0.342 H -73.4 -35.0 NA NA NA
GLU F:431 F:431 64.0 0.337 H -67.7 -41.4 NA NA NA
GLU G:431 G:431 68.0 0.358 H -75.0 -30.1 NA NA NA
GLU H:431 H:431 60.0 0.316 H -71.3 -36.8 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:431 A:431 67.0 0.353 H -67.6 -34.5 6.0 0.032 0.321 B:P09622:0.321
 HOH
 3.025
 OE1
 O
GLU B:431 B:431 61.0 0.321 H -67.8 -36.5 5.0 0.026 0.295 A:P09622:0.295
 HOH
 2.933
 OE1
 O
GLU C:431 C:431 60.0 0.316 H -70.7 -39.1 NA NA NA
GLU D:431 D:431 63.0 0.332 H -67.0 -41.2 NA NA NA
GLU E:431 E:431 61.0 0.321 H -69.5 -40.1 NA NA NA
GLU F:431 F:431 60.0 0.316 H -70.3 -37.9 NA NA NA
GLU G:431 G:431 63.0 0.332 H -66.7 -34.7 NA NA NA
GLU H:431 H:431 62.0 0.326 H -66.9 -38.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 GLU A:431 A:431 65.0 0.342 H -70.6 -38.3 5.0 0.026 0.316 B:P09622:0.316
 HOH
 5.073
 OE1
 O
GLU B:431 B:431 60.0 0.316 H -73.0 -32.2 5.0 0.026 0.29 A:P09622:0.289
 HOH
 5.202
 OE1
 O
GLU C:431 C:431 63.0 0.332 H -66.3 -38.4 NA NA NA
GLU D:431 D:431 66.0 0.347 H -61.5 -45.6 NA NA NA
GLU E:431 E:431 61.0 0.321 H -67.6 -37.5 NA NA NA
GLU F:431 F:431 62.0 0.326 H -68.0 -36.9 NA NA NA
GLU G:431 G:431 63.0 0.332 H -67.7 -41.4 NA NA NA
GLU H:431 H:431 64.0 0.337 H -69.3 -40.6 NA NA NA
GLU I:431 I:431 63.0 0.332 H -64.6 -41.0 NA NA NA
GLU J:431 J:431 63.0 0.332 H -68.4 -30.3 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 GLU A:452 A:431 59.0 0.311 H -62.7 -43.3 4.0 0.021 0.29 B:P09622:0.289
 HOH
 4.378
 H
 O
GLU B:452 B:431 59.0 0.311 H -62.1 -41.4 5.0 0.026 0.285 A:P09622:0.284
 HOH
 2.835
 OE1
 O
GLU C:452 C:431 61.0 0.321 H -62.8 -43.0 NA NA NA
GLU D:452 D:431 61.0 0.321 H -61.1 -42.6 NA NA NA
GLU E:452 E:431 60.0 0.316 H -62.1 -41.1 NA NA NA
GLU F:452 F:431 58.0 0.305 H -60.9 -41.3 NA NA NA
GLU G:452 G:431 59.0 0.311 H -63.4 -42.5 NA NA NA
GLU H:452 H:431 64.0 0.337 H -61.6 -40.8 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 61.0 0.321 H -58.7 -41.0 4.0 0.021 0.3 B:P09622:0.3
 HOH
 2.193
 H
 O
GLU B:453 B:431 59.0 0.311 H -58.8 -41.9 3.0 0.016 0.295 A:P09622:0.295
 HOH
 2.760
 OE1
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 GLU A:453 A:431 62.0 0.326 H -61.6 -42.2 5.0 0.026 0.3 B:P09622:0.3
 HOH
 2.998
 OE1
 O
GLU B:453 B:431 61.0 0.321 H -66.2 -41.5 5.0 0.026 0.295 A:P09622:0.295
 HOH
 2.717
 OE1
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 GLU A:453 A:431 57.0 0.3 H -61.8 -41.0 6.0 0.032 0.268 B:P09622:0.268
 HOH
 2.885
 OE1
 O
GLU B:453 B:431 61.0 0.321 H -62.6 -42.4 5.0 0.026 0.295 A:P09622:0.295
 HOH
 2.828
 OE1
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 61.0 0.321 H -60.4 -40.8 6.0 0.032 0.289 B:P09622:0.289
 HOH
 2.421
 H
 O
GLU B:453 B:431 56.0 0.295 H -60.2 -41.5 6.0 0.032 0.263 A:P09622:0.263
 HOH
 2.813
 OE1
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 62.0 0.326 H -58.3 -40.0 5.0 0.026 0.3 B:P09622:0.3
 HOH
 2.323
 H
 O
GLU B:453 B:431 61.0 0.321 H -59.2 -42.1 6.0 0.032 0.289 A:P09622:0.289
 HOH
 2.835
 OE1
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 61.0 0.321 H -59.5 -42.3 5.0 0.026 0.295 B:P09622:0.295
 HOH
 2.427
 H
 O
GLU B:453 B:431 60.0 0.316 H -61.0 -42.7 5.0 0.026 0.29 A:P09622:0.289
 HOH
 2.848
 OE1
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:453 A:431 64.0 0.337 H -60.8 -42.3 6.0 0.032 0.305 B:P09622:0.305
GLU B:453 B:431 57.0 0.3 H -60.0 -40.3 4.0 0.021 0.279 A:P09622:0.279
 HOH
 9.970
 OE2
 O
GLU C:453 C:431 62.0 0.326 H -60.6 -42.3 NA NA NA
GLU D:453 D:431 60.0 0.316 H -60.0 -41.0 NA NA NA
GLU E:453 E:431 63.0 0.332 H -61.4 -42.0 NA NA NA
GLU F:453 F:431 59.0 0.311 H -59.5 -40.3 NA NA NA
GLU G:453 G:431 62.0 0.326 H -60.0 -42.9 NA NA NA
GLU H:453 H:431 62.0 0.326 H -55.7 -42.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 GLU A:466 A:466 64.0 0.337 H -65.3 -41.3