Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107559516 . A C CCDS5749.1:NM_000108.3:c.1436gAt>gCt_NP_000099.2:p.479D>A Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ASP A:465 A:444 89.0 0.593 H -56.4 -46.8 5.0 0.033 0.56 E:P11182:0.44
B:P09622:0.22
 HOH
 2.575
 OD2
 O
ASP B:465 B:444 94.0 0.627 H -58.1 -45.4 22.0 0.147 0.48 E:P11182:0.373
A:P09622:0.187
 HOH
 9.561
 O
 O
ASP C:465 C:444 99.0 0.66 H -55.8 -37.3 NA NA NA
ASP D:465 D:444 91.0 0.607 H -46.8 -52.0 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ASP A:444 A:444 93.0 0.62 H -50.1 -47.5 1.0 0.007 0.613 K:O00330:0.56
B:P09622:0.16
 HOH
 7.478
 OD2
 O
ASP B:444 B:444 86.0 0.573 H -48.2 -45.3 31.0 0.207 0.366 K:O00330:0.293
A:P09622:0.167
ASP C:444 C:444 89.0 0.593 H -62.6 -39.6 NA NA NA
ASP D:444 D:444 86.0 0.573 H -45.1 -54.1 NA NA NA
ASP E:444 E:444 84.0 0.56 H -66.7 -35.6 NA NA NA
ASP F:444 F:444 81.0 0.54 H -50.5 -45.9 NA NA NA
ASP G:444 G:444 96.0 0.64 H -56.7 -53.3 NA NA NA
ASP H:444 H:444 87.0 0.58 H -62.6 -49.7 NA NA NA
ASP I:444 I:444 88.0 0.587 H -42.5 -43.7 NA NA NA
ASP J:444 J:444 87.0 0.58 H -48.1 -46.7 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 94.0 0.627 H -46.7 -53.5 58.0 0.387 0.24 B:P09622:0.24
 HOH
 2.671
 OD2
 O
ASP B:466 B:444 88.0 0.587 H -45.7 -52.7 48.0 0.32 0.267 A:P09622:0.267
 HOH
 2.748
 OD1
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 76.0 0.507 H -48.5 -52.1 56.0 0.373 0.134 B:P09622:0.133
 HOH
 2.613
 OD1
 O
ASP B:466 B:444 85.0 0.567 H -45.8 -49.6 49.0 0.327 0.24 A:P09622:0.24
 1PE
HOH
 6.640
2.694
 O
OD1
 H262
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ASP A:444 A:444 96.0 0.64 H -54.3 -49.9 66.0 0.44 0.2 B:P09622:0.2
 HOH
 2.563
 O
 O
ASP B:444 B:444 91.0 0.607 H -51.0 -54.4 57.0 0.38 0.227 A:P09622:0.227
 HOH
 2.682
 OD1
 O
ASP C:444 C:444 88.0 0.587 H -49.7 -56.5 NA NA NA
ASP D:444 D:444 95.0 0.633 H -53.0 -43.2 NA NA NA
ASP E:444 E:444 85.0 0.567 H -53.8 -49.5 NA NA NA
ASP F:444 F:444 90.0 0.6 H -54.5 -52.8 NA NA NA
ASP G:444 G:444 91.0 0.607 H -60.2 -54.0 NA NA NA
ASP H:444 H:444 87.0 0.58 H -50.1 -48.9 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ASP A:444 A:444 90.0 0.6 H -53.7 -44.0 63.0 0.42 0.18 B:P09622:0.18
 HOH
 2.476
 OD2
 O
ASP B:444 B:444 87.0 0.58 H -50.0 -55.3 47.0 0.313 0.267 A:P09622:0.267
 HOH
 2.540
 OD1
 O
ASP C:444 C:444 89.0 0.593 H -51.5 -51.5 NA NA NA
ASP D:444 D:444 90.0 0.6 H -56.6 -45.4 NA NA NA
ASP E:444 E:444 87.0 0.58 H -50.7 -48.2 NA NA NA
ASP F:444 F:444 88.0 0.587 H -49.8 -52.4 NA NA NA
ASP G:444 G:444 92.0 0.613 H -51.4 -54.8 NA NA NA
ASP H:444 H:444 88.0 0.587 H -47.8 -51.8 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ASP A:444 A:444 87.0 0.58 H -48.2 -51.8 4.0 0.027 0.553 K:O00330:0.467
B:P09622:0.2
 HOH
 7.520
 OD2
 O
ASP B:444 B:444 85.0 0.567 H -49.6 -58.4 1.0 0.007 0.56 K:O00330:0.52
A:P09622:0.16
 HOH
 2.574
 OD2
 O
ASP C:444 C:444 93.0 0.62 H -58.9 -45.0 NA NA NA
ASP D:444 D:444 88.0 0.587 H -52.7 -46.3 NA NA NA
ASP E:444 E:444 89.0 0.593 H -54.0 -50.1 NA NA NA
ASP F:444 F:444 92.0 0.613 H -51.4 -48.7 NA NA NA
ASP G:444 G:444 93.0 0.62 H -53.7 -46.8 NA NA NA
ASP H:444 H:444 90.0 0.6 H -52.8 -49.7 NA NA NA
ASP I:444 I:444 91.0 0.607 H -51.9 -52.9 NA NA NA
ASP J:444 J:444 86.0 0.573 H -52.5 -49.1 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ASP A:465 A:444 87.0 0.58 H -57.3 -44.6 51.0 0.34 0.24 B:P09622:0.24
 TRS
HOH
 2.745
6.830
 OD2
OD2
 C1
O
ASP B:465 B:444 88.0 0.587 H -59.0 -43.8 53.0 0.353 0.234 A:P09622:0.233
 HOH
 7.242
 O
 O
ASP C:465 C:444 93.0 0.62 H -62.1 -43.7 NA NA NA
ASP D:465 D:444 90.0 0.6 H -59.3 -47.5 NA NA NA
ASP E:465 E:444 90.0 0.6 H -56.8 -45.1 NA NA NA
ASP F:465 F:444 92.0 0.613 H -57.7 -45.0 NA NA NA
ASP G:465 G:444 94.0 0.627 H -59.3 -44.0 NA NA NA
ASP H:465 H:444 92.0 0.613 H -61.1 -44.5 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 83.0 0.553 H -46.3 -54.5 45.0 0.3 0.253 B:P09622:0.253
 HOH
 2.735
 OD2
 O
ASP B:466 B:444 89.0 0.593 H -45.2 -53.1 56.0 0.373 0.22 A:P09622:0.22
 1PE
HOH
 6.882
2.690
 O
OD1
 H232
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 VAL A:466 A:444 53.0 0.342 H -66.1 -44.9 18.0 0.116 0.226 B:P09622:0.226
 HOH
 4.142
 CG2
 O
VAL B:466 B:444 78.0 0.503 H -53.0 -42.6 55.0 0.355 0.148 A:P09622:0.148
 GOL
HOH
 6.459
2.678
 O
O
 O2
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ASP A:466 A:444 87.0 0.58 H -48.7 -50.2 56.0 0.373 0.207 B:P09622:0.207
 HOH
 2.623
 OD1
 O
ASP B:466 B:444 93.0 0.62 H -48.0 -48.4 60.0 0.4 0.22 A:P09622:0.22
 HOH
 2.640
 OD1
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 94.0 0.627 H -51.5 -50.2 63.0 0.42 0.207 B:P09622:0.207
 HOH
 2.719
 OD2
 O
ASP B:466 B:444 89.0 0.593 H -51.3 -47.6 57.0 0.38 0.213 A:P09622:0.213
 HOH
 2.696
 OD1
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 93.0 0.62 H -46.0 -52.3 64.0 0.427 0.193 B:P09622:0.193
 HOH
 2.593
 OD2
 O
ASP B:466 B:444 92.0 0.613 H -45.3 -51.8 56.0 0.373 0.24 A:P09622:0.24
 HOH
 2.672
 OD1
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 85.0 0.567 H -54.3 -54.2 49.0 0.327 0.24 B:P09622:0.24
 HOH
 2.597
 OD2
 O
ASP B:466 B:444 92.0 0.613 H -55.0 -51.7 59.0 0.393 0.22 A:P09622:0.22
 HOH
 2.653
 OD1
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ASP A:466 A:444 88.0 0.587 H -54.3 -51.0 65.0 0.433 0.154 B:P09622:0.153
ASP B:466 B:444 86.0 0.573 H -53.2 -52.2 46.0 0.307 0.266 A:P09622:0.267
 HOH
 2.630
 HA
 O
ASP C:466 C:444 90.0 0.6 H -54.0 -50.3 NA NA NA
ASP D:466 D:444 86.0 0.573 H -51.5 -52.9 NA NA NA
ASP E:466 E:444 82.0 0.547 H -52.6 -51.1 NA NA NA
ASP F:466 F:444 87.0 0.58 H -51.7 -51.3 NA NA NA
ASP G:466 G:444 90.0 0.6 H -53.5 -51.9 NA NA NA
ASP H:466 H:444 90.0 0.6 H -51.5 -51.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ASP A:479 A:479 92.0 0.613 H -54.9 -51.4