Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107559524 . A C CCDS5749.1:NM_000108.3:c.1444Aga>Cga_NP_000099.2:p.482R>R Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ARG A:468 A:447 185.0 0.822 H -83.8 -17.4 73.0 0.324 0.498 E:P11182:0.187
B:P09622:0.316
 HOH
 3.779
 CD
 O
ARG B:468 B:447 186.0 0.827 T -95.9 -1.6 107.0 0.476 0.351 A:P09622:0.351
 HOH
 5.568
 O
 O
ARG C:468 C:447 183.0 0.813 T -95.6 0.4 NA NA NA
ARG D:468 D:447 189.0 0.84 T -84.1 0.2 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ARG A:447 A:447 191.0 0.849 T -71.7 8.4 58.0 0.258 0.591 K:O00330:0.28
B:P09622:0.369
 HOH
 3.761
 NH1
 O
ARG B:447 B:447 170.0 0.756 H -80.1 -31.7 90.0 0.4 0.356 A:P09622:0.356
ARG C:447 C:447 180.0 0.8 T -90.0 -4.5 NA NA NA
ARG D:447 D:447 194.0 0.862 T -83.5 -13.5 NA NA NA
ARG E:447 E:447 170.0 0.756 T -69.8 0.1 NA NA NA
ARG F:447 F:447 173.0 0.769 H -70.0 -32.6 NA NA NA
ARG G:447 G:447 171.0 0.76 T -96.8 10.3 NA NA NA
ARG H:447 H:447 183.0 0.813 H -66.2 -31.1 NA NA NA
ARG I:447 I:447 174.0 0.773 H -86.9 -35.5 NA NA NA
ARG J:447 J:447 189.0 0.84 T -96.7 -10.7 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ARG A:469 A:447 186.0 0.827 H -92.0 -6.1 115.0 0.511 0.316 B:P09622:0.316
 HOH
 5.435
 O
 O
ARG B:469 B:447 189.0 0.84 T -92.6 -1.1 116.0 0.516 0.324 A:P09622:0.324
 HOH
 2.161
 HH11
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:469 A:447 183.0 0.813 H -97.7 -8.3 107.0 0.476 0.337 B:P09622:0.338
 HOH
 2.626
 HG2
 O
ARG B:469 B:447 174.0 0.773 H -96.2 -5.9 105.0 0.467 0.306 A:P09622:0.307
 1PE
HOH
 1.824
2.818
 HH11
O
 OH7
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:447 A:447 179.0 0.796 H -88.7 -7.8 112.0 0.498 0.298 B:P09622:0.298
 HOH
 3.876
 CB
 O
ARG B:447 B:447 186.0 0.827 H -91.6 -5.3 114.0 0.507 0.32 A:P09622:0.32
 HOH
 2.930
 NH1
 O
ARG C:447 C:447 180.0 0.8 H -94.8 -3.5 NA NA NA
ARG D:447 D:447 182.0 0.809 H -83.4 -18.4 NA NA NA
ARG E:447 E:447 184.0 0.818 H -88.5 -4.8 NA NA NA
ARG F:447 F:447 188.0 0.836 H -94.8 -9.0 NA NA NA
ARG G:447 G:447 188.0 0.836 H -95.1 -6.7 NA NA NA
ARG H:447 H:447 188.0 0.836 T -89.5 -5.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:447 A:447 182.0 0.809 H -87.1 -10.3 116.0 0.516 0.293 B:P09622:0.293
 HOH
 3.215
 NH1
 O
ARG B:447 B:447 187.0 0.831 H -88.2 -4.7 116.0 0.516 0.315 A:P09622:0.316
 HOH
 2.781
 NH1
 O
ARG C:447 C:447 184.0 0.818 H -90.4 -5.0 NA NA NA
ARG D:447 D:447 184.0 0.818 T -87.4 -5.5 NA NA NA
ARG E:447 E:447 186.0 0.827 H -90.9 -7.5 NA NA NA
ARG F:447 F:447 185.0 0.822 H -87.6 -8.5 NA NA NA
ARG G:447 G:447 188.0 0.836 H -91.3 -7.1 NA NA NA
ARG H:447 H:447 184.0 0.818 T -91.1 -5.4 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ARG A:447 A:447 176.0 0.782 H -69.6 -43.5 72.0 0.32 0.462 K:O00330:0.102
B:P09622:0.364
 HOH
 7.717
 NH2
 O
ARG B:447 B:447 186.0 0.827 T -89.2 2.0 60.0 0.267 0.56 K:O00330:0.271
A:P09622:0.329
 HOH
 8.161
 O
 O
ARG C:447 C:447 189.0 0.84 T -85.6 2.4 NA NA NA
ARG D:447 D:447 187.0 0.831 H -77.7 -21.3 NA NA NA
ARG E:447 E:447 190.0 0.844 T -86.8 -3.2 NA NA NA
ARG F:447 F:447 183.0 0.813 T -84.3 -7.2 NA NA NA
ARG G:447 G:447 187.0 0.831 H -82.5 -15.8 NA NA NA
ARG H:447 H:447 185.0 0.822 H -86.1 -10.0 NA NA NA
ARG I:447 I:447 189.0 0.84 T -87.3 -3.4 NA NA NA
ARG J:447 J:447 177.0 0.787 H -76.1 -15.9 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ARG A:468 A:447 185.0 0.822 T -86.3 -5.5 110.0 0.489 0.333 B:P09622:0.333
 TRS
HOH
 7.332
8.459
 HD2
C
 O2
O
ARG B:468 B:447 185.0 0.822 T -85.3 -5.7 95.0 0.422 0.4 A:P09622:0.4
 HOH
 4.107
 O
 O
ARG C:468 C:447 183.0 0.813 T -88.2 -6.5 NA NA NA
ARG D:468 D:447 193.0 0.858 T -87.8 -2.6 NA NA NA
ARG E:468 E:447 182.0 0.809 T -87.5 -4.6 NA NA NA
ARG F:468 F:447 200.0 0.889 T -86.5 -6.1 NA NA NA
ARG G:468 G:447 184.0 0.818 T -88.0 -7.2 NA NA NA
ARG H:468 H:447 187.0 0.831 T -87.7 -6.2 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:469 A:447 187.0 0.831 T -92.7 -2.0 113.0 0.502 0.329 B:P09622:0.329
 HOH
 3.155
 HG2
 O
ARG B:469 B:447 172.0 0.764 T -91.2 -1.4 93.0 0.413 0.351 A:P09622:0.351
 1PE
HOH
 2.100
2.775
 HH11
O
 OH2
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ARG A:469 A:447 167.0 0.742 H -78.5 -24.6 132.0 0.587 0.155 B:P09622:0.156
 HOH
 3.075
 NH1
 O
ARG B:469 B:447 183.0 0.813 T -83.4 -8.5 112.0 0.498 0.315 A:P09622:0.316
 GOL
HOH
 2.530
2.894
 O
NH1
 O2
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ARG A:469 A:447 187.0 0.831 T -94.2 -1.3 102.0 0.453 0.378 B:P09622:0.378
 HOH
 2.840
 NH1
 O
ARG B:469 B:447 190.0 0.844 T -89.4 -2.4 105.0 0.467 0.377 A:P09622:0.378
 HOH
 2.735
 O
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:469 A:447 190.0 0.844 H -91.6 -2.8 103.0 0.458 0.386 B:P09622:0.387
 HOH
 2.450
 HD3
 O
ARG B:469 B:447 192.0 0.853 T -92.3 -1.6 107.0 0.476 0.377 A:P09622:0.378
 HOH
 2.164
 HH11
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:469 A:447 191.0 0.849 T -93.7 -3.3 116.0 0.516 0.333 B:P09622:0.333
 HOH
 2.913
 HB2
 O
ARG B:469 B:447 191.0 0.849 T -90.4 -0.8 110.0 0.489 0.36 A:P09622:0.36
 HOH
 2.103
 HH11
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:469 A:447 60.0 0.8 T -86.3 -5.4 47.0 0.627 0.173 B:P09622:0.173
 HOH
 3.173
 HA3
 O
GLY B:469 B:447 61.0 0.813 T -82.1 -7.2 45.0 0.6 0.213 A:P09622:0.213
 HOH
 2.850
 O
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:469 A:447 180.0 0.8 H -88.7 -7.1 105.0 0.467 0.333 B:P09622:0.333
 HOH
 8.468
 HH22
 O
ARG B:469 B:447 182.0 0.809 H -91.2 -9.3 113.0 0.502 0.307 A:P09622:0.307
 HOH
 2.287
 HH11
 O
ARG C:469 C:447 181.0 0.804 H -86.9 -6.1 NA NA NA
ARG D:469 D:447 186.0 0.827 H -91.0 -9.6 NA NA NA
ARG E:469 E:447 185.0 0.822 H -90.6 -6.2 NA NA NA
ARG F:469 F:447 184.0 0.818 H -89.9 -7.4 NA NA NA
ARG G:469 G:447 187.0 0.831 T -90.0 -5.5 NA NA NA
ARG H:469 H:447 185.0 0.822 H -91.2 -8.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ARG A:482 A:482 165.0 0.733 H -86.0 -10.2