Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107559657 . A C CCDS5749.1:NM_000108.3:c.1483Aga>Cga_NP_000099.2:p.495R>R Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ARG A:481 A:460 57.0 0.253 H -60.5 -52.8 19.0 0.084 0.169 B:P09622:0.169
 HOH
 6.827
 N
 O
ARG B:481 B:460 73.0 0.324 H -61.2 -45.7 28.0 0.124 0.2 A:P09622:0.2
 HOH
 4.899
 CD
 O
ARG C:481 C:460 69.0 0.307 H -61.2 -49.6 NA NA NA
ARG D:481 D:460 71.0 0.316 H -66.3 -44.0 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ARG A:460 A:460 61.0 0.271 H -71.6 -43.5 28.0 0.124 0.147 B:P09622:0.147
 HOH
 4.139
 NH2
 O
ARG B:460 B:460 73.0 0.324 H -64.8 -47.5 43.0 0.191 0.133 A:P09622:0.133
 HOH
 8.896
 N
 O
ARG C:460 C:460 78.0 0.347 H -49.1 -58.3 NA NA NA
ARG D:460 D:460 72.0 0.32 H -65.2 -49.8 NA NA NA
ARG E:460 E:460 73.0 0.324 H -57.2 -50.8 NA NA NA
ARG F:460 F:460 76.0 0.338 H -67.7 -50.6 NA NA NA
ARG G:460 G:460 74.0 0.329 H -88.8 -34.7 NA NA NA
ARG H:460 H:460 67.0 0.298 H -62.1 -53.9 NA NA NA
ARG I:460 I:460 70.0 0.311 H -94.8 -58.2 NA NA NA
ARG J:460 J:460 80.0 0.356 H -53.8 -45.2 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ARG A:482 A:460 71.0 0.316 H -56.0 -50.9 25.0 0.111 0.205 B:P09622:0.204
 HOH
 7.539
 H
 O
ARG B:482 B:460 83.0 0.369 H -51.9 -50.9 11.0 0.049 0.32 A:P09622:0.32
 HOH
 7.113
 H
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:482 A:460 71.0 0.316 H -57.0 -48.9 13.0 0.058 0.258 B:P09622:0.258
 HOH
 3.134
 HD3
 O
ARG B:482 B:460 71.0 0.316 H -54.5 -49.3 10.0 0.044 0.272 A:P09622:0.271
 1PE
HOH
 2.967
2.068
 HH22
HE
 H261
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:460 A:460 69.0 0.307 H -63.2 -49.4 30.0 0.133 0.174 B:P09622:0.173
 HOH
 6.751
 N
 O
ARG B:460 B:460 69.0 0.307 H -60.3 -44.7 29.0 0.129 0.178 A:P09622:0.178
 HOH
 3.443
 NH2
 O
ARG C:460 C:460 73.0 0.324 H -60.8 -42.2 NA NA NA
ARG D:460 D:460 68.0 0.302 H -71.7 -39.3 NA NA NA
ARG E:460 E:460 70.0 0.311 H -62.5 -39.2 NA NA NA
ARG F:460 F:460 73.0 0.324 H -62.9 -45.7 NA NA NA
ARG G:460 G:460 70.0 0.311 H -63.0 -51.3 NA NA NA
ARG H:460 H:460 70.0 0.311 H -66.7 -40.5 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ARG A:460 A:460 68.0 0.302 H -59.9 -54.6 26.0 0.116 0.186 B:P09622:0.187
 HOH
 3.473
 NH2
 O
ARG B:460 B:460 70.0 0.311 H -58.4 -44.9 27.0 0.12 0.191 A:P09622:0.191
 HOH
 2.744
 NH1
 O
ARG C:460 C:460 69.0 0.307 H -59.9 -47.2 NA NA NA
ARG D:460 D:460 69.0 0.307 H -59.0 -50.1 NA NA NA
ARG E:460 E:460 66.0 0.293 H -63.9 -42.3 NA NA NA
ARG F:460 F:460 73.0 0.324 H -56.8 -48.6 NA NA NA
ARG G:460 G:460 69.0 0.307 H -59.9 -50.3 NA NA NA
ARG H:460 H:460 68.0 0.302 H -58.6 -45.1 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ARG A:460 A:460 68.0 0.302 H -61.4 -49.0 23.0 0.102 0.2 B:P09622:0.2
 HOH
 8.399
 N
 O
ARG B:460 B:460 81.0 0.36 H -61.2 -49.3 39.0 0.173 0.187 A:P09622:0.187
 HOH
 8.431
 N
 O
ARG C:460 C:460 74.0 0.329 H -60.7 -43.0 NA NA NA
ARG D:460 D:460 74.0 0.329 H -64.8 -44.1 NA NA NA
ARG E:460 E:460 75.0 0.333 H -66.6 -46.7 NA NA NA
ARG F:460 F:460 77.0 0.342 H -62.8 -45.0 NA NA NA
ARG G:460 G:460 72.0 0.32 H -65.0 -46.7 NA NA NA
ARG H:460 H:460 74.0 0.329 H -65.0 -45.3 NA NA NA
ARG I:460 I:460 67.0 0.298 H -63.6 -43.8 NA NA NA
ARG J:460 J:460 75.0 0.333 H -65.8 -43.4 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ARG A:481 A:460 74.0 0.329 H -61.1 -49.2 27.0 0.12 0.209 B:P09622:0.209
 HOH
 2.066
 HH11
 O
ARG B:481 B:460 76.0 0.338 H -60.9 -47.8 29.0 0.129 0.209 A:P09622:0.209
 HOH
 6.526
 HH12
 O
ARG C:481 C:460 76.0 0.338 H -62.4 -47.4 NA NA NA
ARG D:481 D:460 74.0 0.329 H -60.4 -46.8 NA NA NA
ARG E:481 E:460 69.0 0.307 H -60.7 -51.9 NA NA NA
ARG F:481 F:460 75.0 0.333 H -60.4 -47.3 NA NA NA
ARG G:481 G:460 69.0 0.307 H -61.1 -47.3 NA NA NA
ARG H:481 H:460 72.0 0.32 H -61.7 -47.1 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:482 A:460 71.0 0.316 H -59.0 -49.7 25.0 0.111 0.205 B:P09622:0.204
 HOH
 7.878
 N
 O
ARG B:482 B:460 80.0 0.356 H -53.5 -49.7 11.0 0.049 0.307 A:P09622:0.307
 HOH
 7.649
 N
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ARG A:482 A:460 65.0 0.289 H -57.6 -46.6 22.0 0.098 0.191 B:P09622:0.191
 HOH
 2.662
 NH1
 O
ARG B:482 B:460 71.0 0.316 H -53.7 -50.5 33.0 0.147 0.169 A:P09622:0.169
 GOL
HOH
 4.709
2.886
 NH2
NH1
 C1
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 GLY A:482 A:460 8.0 0.107 H -55.6 -45.7 8.0 0.107 0.0 HOH
 3.274
 CA
 O
GLY B:482 B:460 7.0 0.093 H -57.5 -44.5 7.0 0.093 0.0 HOH
 3.893
 C
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLY A:482 A:460 7.0 0.093 H -59.4 -44.8 7.0 0.093 0.0 HOH
 2.768
 HA3
 O
GLY B:482 B:460 7.0 0.093 H -58.5 -43.5 7.0 0.093 0.0 HOH
 3.142
 HA3
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:482 A:460 80.0 0.356 H -55.9 -48.5 12.0 0.053 0.303 B:P09622:0.302
 HOH
 2.819
 HH22
 O
ARG B:482 B:460 84.0 0.373 H -52.1 -49.6 11.0 0.049 0.324 A:P09622:0.324
 HOH
 2.349
 HE
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:482 A:460 75.0 0.333 H -60.0 -46.1 29.0 0.129 0.204 B:P09622:0.204
 HOH
 1.908
 HH11
 O
ARG B:482 B:460 72.0 0.32 H -55.2 -48.8 29.0 0.129 0.191 A:P09622:0.191
 HOH
 7.213
 H
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ARG A:482 A:460 67.0 0.298 H -64.6 -47.9 22.0 0.098 0.2 B:P09622:0.2
 FAD
HOH
 9.737
8.614
 HH12
HB3
 O2
O
ARG B:482 B:460 65.0 0.289 H -65.3 -45.3 23.0 0.102 0.187 A:P09622:0.187
 HOH
 5.778
 HH21
 O
ARG C:482 C:460 78.0 0.347 H -63.6 -45.0 NA NA NA
ARG D:482 D:460 65.0 0.289 H -65.2 -46.4 NA NA NA
ARG E:482 E:460 77.0 0.342 H -64.8 -45.5 NA NA NA
ARG F:482 F:460 70.0 0.311 H -64.8 -46.1 NA NA NA
ARG G:482 G:460 73.0 0.324 H -64.5 -45.7 NA NA NA
ARG H:482 H:460 70.0 0.311 H -65.7 -44.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ARG A:495 A:495 78.0 0.347 H -57.3 -50.7